The elbow region is the most common site at which the ulnar nerve is prone to a localized neuropathy. Diagnosis of ulnar nerve entrapment at elbow is made on the basis of history, lacal neurologic finding, nerve conduction studies and electromyography. Electrophysiologic test is simple, relatively quick, and accurate method for the diagnosis of peripheral nerve lesion. Therefore, electrodisgnosis makes it possible to identify and localize the early stage of entrapment lesion. Definitive diagnosis of ulnar nerve entrapment at elbow requires electromyographic demonstration of decreased ulnar nerve conduction velocity across the elbow and depressed sensory nerve action potentials. The purpose of this study were to analyze the electrophysiologic findings of patients with an established ulnar nerve entrapment at elbow compared to normal eonduction velocity of our laboratory. And we evaluate the correlation of clinical symptom with the electromyographic findings. Twenty five subjects were studied, 22 men and 3 women, aged from 5 to 62 years. The results were as follows . 1. The mean motor conduction velocity of ulnar nerve across elbow were 32.85±10.21 m/sec. The longer duration of symptom were, the slower conduction veloctity across elbow were. 2. Among the 25 patients, motor conduction velocity of ulnar nerve at forearm segment decreased in 15 patients(60%). As the motor conduction velocity of the ulnar nerve across elbow became slower, thst of forearm segment were slower. 3. In 19 patients (76%) among the 25 patients, sensory evoked potentials revealed prolonged distal latency or were not evoked. 4. On needle electrodiagnostic study, positive sharp wave or fibrillation potentials could be found in abductor digiti minimi first dorsal interosseus and/or flexor carpi ulnaris muscles in 22 patients(88%).
Action Potentials ; Diagnosis ; Elbow ; Electromyography ; Evoked Potentials ; Female ; Forearm ; Humans ; Male ; Methods ; Muscles ; Needles ; Neural Conduction ; Neurologic Manifestations ; Peripheral Nerves ; Ulnar Nerve Compression Syndromes ; Ulnar Nerve

No abstract available.

No abstract available.
Urinary Retention*

We have experienced a case of neurofibromatosis with unusual giant pigmentation, which presents itself as a 28 cm x 40 cm sized, serrated bordered light brownish patch speckled with small dark hyperpigmented macules on his back. Histopathologic examinations of light brown patch and speckles showed only an increase in basal melanin pigmentation.
Melanins ; Neurofibromatoses* ; Pigmentation*

The effect of androgen in the development of the normal prostate and the evolution of benign prostatic hypertrophy (BPH), and prostatic adenocarcinoma has been proven. In addition to androgen, estrogen and progesterone are also thought to play a role in the pathogenesis of BPH and carcinoma. However, their exact roles are not yet known because there is no conclusive evidence. Thirty cases of prostatic adenocarcinoma and 16 cases of BPH were studied. Immunohistochemical staining for estrogen receptor (ER) and progesterone receptor (PR) in epithelial and stromal cells, respectively was performed and the results were assessed semiquantitatively based on the number of positive cells per 100 total cells. Slides were scored as negative; less than 5% of cells, 1 ; 6~15% of cells, 2 ; 16~25% of cells, and 3 ; more than 26% of cells. The relationship between ER and PR expression and the patient's age, histologic grade, and clinical stage was evaluated in prostatic adenocarcinomas. ER was negative in epithelial and in stromal cells for all prostatic adenocarcinomas and BPH cases. The PR expression in epithelial cells and in stromal cells of BPH was noted in 15 (93.8%) and 16 (100.0%) out of 16, respectively. The PR expression of carcinoma cells and stromal cells in prostatic adenocarcinoma was found in 28 (93.3%) and 23 out of 30 (76.7%), respectively. The PR immunoreactivities of stromal cells around carcinoma were 3 in 18 cases, 2 in one case, and 1 in 4 cases, but those of epithelial and stromal cells of BPH and carcinoma cells of prostatic carcinoma were similar to each other with a value of 3 in most cases. The PR expression rate of stromal cells around carcinoma was significantly correlated with the patient's age (p=0.044), but not with histologic grade and clinical stage. In summary, estrogen does not have a direct effect on the biological behavior of BPH and prostatic adenocarcinoma, but progesterone appears to play a role in the pathogenesis of BPH and prostatic adenocarcinoma. Further studies should clarify the biological role of progesterone in the human prostate.
Adenocarcinoma* ; Epithelial Cells ; Estrogens* ; Humans ; Progesterone* ; Prostate ; Prostatic Hyperplasia* ; Receptors, Progesterone* ; Stromal Cells

No abstract available.
Humans ; Temporomandibular Joint Disorders* ; Temporomandibular Joint*

Detailed mechanism of uterine cervical cancer progression still remains unclear. Altered programmed cell death (apoptosis) and cellular proliferation are associated with the development of neoplasia. The authors investigated the expressions of bcl-2, which inhibit apoptosis, and caspase-3, which is involved in the induction of apoptosis and has been considered to be correlated with apoptosis, and proliferating activity according to the degree of malignancy in the squamous neoplasia of the uterine cervix. Correlation between bcl-2 and caspase-3 expression and proliferating activity was done. The materials were low grade squamous intraepithelial lesions (LSIL, n=15), high-grade squamous intraepithelial lesions (HSIL, n=15), microinvasive squamous cell carcinoma (n=15), and squamous cell carcinoma (n=15). Immunohistochemical stainings for bcl-2, caspase-3, and MIB-1 were done. bcl-2 and MIB-1 expressions were progressively increased in accordance with the increasing degree of malignancy, but caspase-3 immunoreactivity was higher in LSIL than invasive cancers. There was an inverse relationship between bcl-2 and caspase-3 expression, but the difference did not reach statistical significance. No significant correlation between MIB-1, bcl-2, and caspase-3 expressions was observed. These results suggest that an inhibition of apoptosis and the augmentation of proliferating activity of tumor cells might be separately involved in the development of the cervical squamous neoplasia.
Apoptosis ; Carcinoma, Squamous Cell ; Caspase 3* ; Cell Death ; Cell Proliferation ; Cervix Uteri* ; Female ; Uterine Cervical Neoplasms

No abstract available.
Hand* ; Thoracic Outlet Syndrome*

No abstract available.
Elbow*

A case of gouty polyarthropathy accompanied with carpal tunnel syndrom is reporte, in a 70 year old man. The patient was treated by removal of tophaceous materials surgically in both knee and right wrist joints for the relief of pain. There was a relatively good result postoperatively in the aspect of pain free motion of joints, but he was died of the complication of gouty nephropathy 4 months later after discharge.
Arthritis ; Gout ; Humans ; Joints ; Knee ; Wrist ; Wrist Joint