OBJECTIVE: To systematically understand natural philosophical medical mode that is the important component part of theoretical medicine studies, to further explain its theoretical values and application significance, so as to promote the constant improvement of medical mode.DATA SOURCES: Based on Social Medicine---Evolution of Medical Mode---Empirical Medical Mode, synthesized the features of TCM, Chinese thought history, Chinese cultural history and the research method features, puts forward to the systematic understanding of natural philosophical medical mode.STUDY SELECTION: Data was selected from social medical data, TCM data, Chinese cultural data and thought history data. The selected data can embody outlook of nature, abstract thinking features and mode features.The data was analyzed and grouped to reveal the application of the thoughts and methods of natural philosophy in the understanding of health and diseases.DATA EXTRACTION: Among 23 papers, the data was mainly selected from 6 papers including Shanggu Tianzhen Lun, Shengqi Tongtian Lun and Zangqi Fa Shi Lun. The thoughts, theory and understanding from these materials are used to expound the natural and social phenomena of the human body, and get the conclusion that the qualitative analysis is sufficient,while the quantitative concepts are scanty; subjective experiences and clinical disproof theory are plentiful while concrete proof analysis and morphological injury principles are scarce.DATA SYNTHESIS: Based on the influences of holism and methodology of natural philosophy, the natural philosophical medical mode can only grasp the life phenomena organically. It attaches importance to the generalization of the relationships and phenomena above the level of the human body, but pays less attention to the concrete structure analysis below the level of human body. Therefore it emphasizes the interactive roles of the four-dimension structure of the heaven, earth, people and ethics in human health and diseases, invented many difficult material concepts to specify the physiological and pathological concepts. The life principles are invariable, the content of qi mechanism remains constant. All diseases can be understood, syndrome-differentiated and presc ribed. However the medical concepts are mostly cited from ancient philosophical concepts and the general level of medical theory remains in this level of thoughts.CONCLUSION: Natural philosophical medical mode centers upon social science, social phenomena and social psychology as its main tool. It attaches more importance to the essential attribute of man, namely the social attribute. By contrast the biological medical mode attaches importance to the natural attribute of man. namely the biological attribute. The two factors constitute the two sides of one thing. Compared with the present medical mode of biology---psychology---society, the natural philosophical medical mode not only has its systematic nature and holism, but also clinical therapeutic theory and more operational nature. It may enlighten people's wisdom and is an art of understanding health and diseases. Thus it possesses very important research significance and clinical application values.

Acute Disease ; Adult ; Arsenic Poisoning ; Female ; Humans ; Male ; Middle Aged ; Young Adult

Castleman Disease ; therapy ; Humans ; Medicine, Chinese Traditional ; Syndrome

Objective: To provide reference for on-site medical emergency preparedness and response to nuclear facilities of our country. Methods: On the basis of laws, regulations and standards as well as our experience and research in this field. Results: To provide effective advice for on-site medical emergency preparedness and response. Conclusion:Introduce unclear accident influence, unclear accident emergency system and so on.

Objective To establish human neural stem cells(HNSCs) model for further basic research and clinical application. Methods Cells from human fetal cerebral cortex were collected and cultured with serum free midium and then identified for nestin immunocytochemical staning;The cells were induced to differentiate by 5% fetal bovin serum and identified by neurofilament-200(NF-200) and glial fibrillary acidic protein(GFAP) immunocytochemical staning. Results The harvested cells appeared as clusters in suspension and both NF-200 and GFAP positive cells were observed after induction.After 12 generations of culture,these cells retained the main characteristics of NSCs.Conclusions The HNSCs were harvested from human fetal cerebral cortex and this HNSCs model can be used for futher basic research and clinical applications.;

Adenocarcinoma ; drug therapy ; immunology ; Aged ; Aged, 80 and over ; Carcinoma, Squamous Cell ; drug therapy ; immunology ; Drugs, Chinese Herbal ; therapeutic use ; Female ; Humans ; Killer Cells, Natural ; immunology ; Lung Neoplasms ; drug therapy ; immunology ; Male ; Middle Aged ; Phytotherapy ; Quality of Life ; T-Lymphocyte Subsets ; immunology

Antigens, CD19 ; analysis ; Asthma ; blood ; Child ; Child, Preschool ; Female ; Flow Cytometry ; Humans ; Immunoglobulin E ; blood ; Lymphocytes ; immunology ; Male ; Receptors, IgE ; analysis

As the basis of the health management of the elderly, weight management should receive attention from medical practitioners.However, there is an ongoing debate on the ideal range of body mass index for elderly in China.This article aimed to find the suitable body mass index for Chinese old people by reviewing the literature regarding the body mass and obesity of the elderly.Lots of evidence show that overweight and mild obesity appear to be the optimal weight status for the elderly.

Objective To investigate the effect of platelet-rich plasma (PRP) on starting of wnt3 gene and klotho gene of adipose-derived stem cells (ADSCs) of rabbit.Methods Epididymal adipose tissue stem cells were obtained from New Zealand white rabbits,and the cells identified by morphology and inducing differentiation,and the cells were cultured to the fourth generation,PRP and PPP (platelet-poor plasma) were prepared by traditional centrifugal method from abdominal aortic of rabbit; ADSCs were cultured in culture medium containing PRP (experimental group),PPP (control group) and all medium (blank group) for each 5％ for 24h,48h and 72h.Cells of each group were dissociated and total RNA extracted.Effects of the starting of wnt3 gene and klotho gene were detected by RT-PCR.Results Primary ADSCs of rabbit grew in the way of long spindle swirly.The results of oil red O and alizarin red staining of the ADSCs were positive.Expression of wnt3 gene and klotho gene in the experimental group significantly increased from the results of RT-PCR (P＜0.05).Conclusions PRP can promote proliferation of the ADSCs of rabbit and increase the expression of wnt3 gene and klotho gene significantly.

Objective To study the effect of Src tyrosine kinase inhibition on subcutaneously transplanted tumor of human lung adenocarcinoma in mice and its mechanism. Methods For the subcutaneously transplanted tumor model, A549 cells or PC-9 cells were inoculated into SCID mice by subcutaneous injection. Immunohistochemistry was used to show the effect of Src tyrosine kinase inhibition on proliferation index (Ki-67 staining) and microvessel density (CD31 staining) of subcutaneously transplanted tumor of human lung adenocarcinoma in mice. Results Subcutaneously transplanted tumor of PC-9 cells was sensitive to src tyrosine kinase inhibitor. There was significant difference between treatment group and control group (P <0.01). There was significant difference between the two treatment group too (P <0.01). Stopping treatment for 1 week, the inhibition rate of tumor growth were 33.19 % and 84.79 % in 10 mg·kg-1·d-1 and 50 mg·kg-1·d-1 treatment group, respectively. The same treatment was less effective to subcutaneous tumors produced by A549 cells. Treatment with 50 mg·kg-1·d-1 Src tyrosine kinase inhibitor significantly reduced the proliferation index of subcutaneously transplanted tumor produced by PC-9 cells (P<0.01) and tended to reduce the proliferation index of subcutaneously transplanted tumor produced by A549 cells (P >0.05). Treatment with 50 mg·kg-1·d-1 Src tyrosine kinase inhibitor significantly reduced micro vascular density in both PC-9 and A549 induced subcutaneous tumors (P <0.05). Conclusion Inhibition of Src tyrosine kinase could suppress the progression of subcutaneously transplanted tumor, not only by the inhibition of cell proliferation of lung adenocarcinoma cells directly, but also by the inhibition of angiogenesis indirectly.