1.Erratum: A Case of Acute Pyogenic Sacroiliitis and Bacteremia Caused by Community-Acquired Methicillin-Resistant Staphylococcus aureus.
Suyoung KIM ; Kang Lock LEE ; Hae Lim BAEK ; Seung Jun JANG ; Song Mi MOON ; Yong Kyun CHO
Infection and Chemotherapy 2014;46(1):66-66
We found an error in our published article. Figure 2 should be corrected.
2.A Case of Acute Pyogenic Sacroiliitis and Bacteremia Caused by Community-Acquired Methicillin-Resistant Staphylococcus aureus.
Suyoung KIM ; Kang Lock LEE ; Hae Lim BAEK ; Seung Jun JANG ; Song Mi MOON ; Yong Kyun CHO
Infection and Chemotherapy 2013;45(4):441-445
Pyogenic sacroiliitis is a rare osteoarticular infection, occurring most frequently in children and young adults. Diagnosis of the disease is challenging because of a general lack of awareness of the disease and its nonspecific signs and symptoms. Staphylococcus aureus is the most common causative bacteria in pyogenic sacroiliitis. Methicillin-resistant S. aureus (MRSA) has typically been considered a hospital-associated pathogen; however, community-acquired (CA)-MRSA infections are becoming increasingly common in Korea. We report the first domestic case of acute pyogenic sacroiliitis with abscess and bacteremia caused by CA-MRSA. The pathogen carried the type IV-A staphylococcal cassette chromosome mec (SCCmec) without the Panton-Valentine leukocidin (PVL) gene, and was identified as sequence type (ST) 72 by multilocus sequence typing.
Abscess
;
Bacteremia*
;
Bacteria
;
Child
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Community-Acquired Infections
;
Diagnosis
;
Humans
;
Korea
;
Leukocidins
;
Methicillin Resistance*
;
Methicillin-Resistant Staphylococcus aureus*
;
Multilocus Sequence Typing
;
Sacroiliitis*
;
Staphylococcus aureus
;
Young Adult
3.Erratum: A Case of Acute Pyogenic Sacroiliitis and Bacteremia Caused by Community-Acquired Methicillin-Resistant Staphylococcus aureus.
Su Young KIM ; Kang Lock LEE ; Hae Lim BAEK ; Seung Jun JANG ; Song Mi MOON ; Yong Kyun CHO
Infection and Chemotherapy 2015;47(4):303-303
We found an error in our published article. Author name should be corrected.
4.Genetic Analysis of Multiple Endocrine Neoplasia Type 1 (MEN1) Leads to Misdiagnosis of an Extremely Rare Presentation of Intrasellar Cavernous Hemangioma as MEN1.
Dong Min LEE ; Seung Hee YU ; Hyun Hwa YOON ; Kang Lock LEE ; Young Sil EOM ; Kiyoung LEE ; Byung Joon KIM ; Yeun Sun KIM ; Ie Byung PARK ; Kwang Won KIM ; Sihoon LEE
Endocrinology and Metabolism 2014;29(2):146-153
BACKGROUND: Multiple endocrine neoplasia type 1 (MEN1) is a rare inherited disorder characterized by the simultaneous occurrence of endocrine tumors in target tissues (mainly the pituitary, endocrine pancreas, and parathyroid glands). MEN1 is caused by mutations in the MEN1 gene, which functions as a tumor suppressor and consists of one untranslated exon and nine exons encoding the menin protein. This condition is usually suspected when we encounter patients diagnosed with tumors in multiple endocrine organs, as mentioned above. METHODS: A 65-year-old woman who underwent surgery for a pancreatic tumor (serous cystadenoma) 5 years previously was referred to our hospital due to neurologic symptoms of diplopia and left ptosis. Brain magnetic resonance imaging revealed a 3.4-cm lesion originating from the cavernous sinus wall and extending into the sellar region. It was thought to be a nonfunctioning tumor from the results of the combined pituitary function test. Incidentally, we found that she also had a pancreatic tumor, indicating the necessity of genetic analysis for MEN1. RESULTS: Genomic analysis using peripheral leukocytes revealed a heterozygous c.1621G>A mutation in the MEN1 gene that was previously reported to be either a pathogenic mutation or a simple polymorphism. We pursued a stereotactic approach to the pituitary lesion, and microscopic findings of the tumor revealed it to be an intrasellar cavernous hemangioma, a rare finding in the sellar region and even rarer in relation to oculomotor palsy. The patient recovered well from surgery, but refused further evaluation for the pancreatic lesion. CONCLUSION: There is great emphasis placed on genetic testing in the diagnosis of MEN1, but herein we report a case where it did not assist in diagnosis, hence, further discussion on the role of genetic testing in this disease is needed. Also, in cases of pituitary tumor with cranial nerve palsy, despite its low prevalence, intrasellar cavernous hemangioma could be suspected.
Aged
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Brain
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Cavernous Sinus
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Cranial Nerve Diseases
;
Diagnosis
;
Diagnostic Errors*
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Diplopia
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Exons
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Female
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Genetic Testing
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Hemangioma, Cavernous*
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Humans
;
Islets of Langerhans
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Leukocytes
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Magnetic Resonance Imaging
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Multiple Endocrine Neoplasia Type 1*
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Neurologic Manifestations
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Paralysis
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Pituitary Function Tests
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Pituitary Neoplasms
;
Prevalence
5.Nocardia Brain Abscess in an Immunocompetent Patient.
Suyoung KIM ; Kang Lock LEE ; Dong Min LEE ; Ji Hun JEONG ; Song Mi MOON ; Yiel Hae SEO ; Chan Jong YOO ; Dongki YANG ; Yong Kyun CHO ; Yoon Soo PARK
Infection and Chemotherapy 2014;46(1):45-49
Nocardia cerebral abscess is rare, constituting approximately 1-2% of all cerebral abscesses. Mortality for a cerebral abscess of Nocardia is three times higher than that of other bacterial cerebral abscesses, therefore, early diagnosis and therapy is important. Nocardia cerebral abscess is generally occur among immunocompromised patients, and critical infection in immunocompetent patients is extremely rare. We report on a case of a brain abscess by Nocardia farcinica in an immunocompetent patient who received treatment with surgery and antibiotics. This is the second case of a brain abscess caused by N. farcinica in an immunocompetent patient in Korea.
Anti-Bacterial Agents
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Brain Abscess*
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Brain*
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Early Diagnosis
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Humans
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Immunocompetence
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Immunocompromised Host
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Korea
;
Mortality
;
Nocardia Infections
;
Nocardia*
6.Erratum: Nocardia Brain Abscess in an Immunocompetent Patient.
Su Young KIM ; Kang Lock LEE ; Dong Min LEE ; Ji Hun JEONG ; Song Mi MOON ; Yiel Hae SEO ; Chan Jong YOO ; Dongki YANG ; Yong Kyun CHO ; Yoon Soo PARK
Infection and Chemotherapy 2015;47(4):304-304
We found an error in our published article. Author name should be corrected.