2.Giant cell tumor of distal femur treated by allograft: a case report.
The Journal of the Korean Orthopaedic Association 1992;27(1):412-416
No abstract available.
Allografts*
;
Femur*
;
Giant Cell Tumors*
;
Giant Cells*
3.A clinical study of the carpal tunnel syndrome.
The Journal of the Korean Orthopaedic Association 1993;28(2):654-660
No abstract available.
Carpal Tunnel Syndrome*
4.Expression of p53 Protein and Proliferating Cell Nuclear Antigen in Epstein - Barr Virus-associated Gastric Adenocarcinoma.
Jeong Hee KANG ; Chang Hoon LEE ; Kang Suek SUH
Journal of the Korean Cancer Association 1999;31(3):429-440
PURPOSE: Recently, it has been reported that Epstein-Barr virus (EBV) is associated with some gastric cancers. But EBVs role in EBV-associated gastric carcinomas (EBVaGCs) has not been fully elucidated. This study was undertaken to evaluate the characteristics of EBVaGCs and to compare those with non-EBVaGCs. MATERIALS AND METHODS: EBV infection was studied using paraffin-embedded tissue blocks of 119 cases of gastric adenocarcinomas by in situ hybridization for EBV-encoded small RNAs (EBERs). In EBVaGCs and non-EBVaGCs, molecular characteristics were evaluated by immunohistochemical staining for latent membrane protein (LMP)-1, p53 protein, and proliferating cell nuclear antigen (PCNA). RESULTS: EBERs were detected in 12 cases (10.1%) of 119 gastric adenocarcinomas. LMP-1 was negative in all carcinomas tested, p53 protein was positive in 7 cases (58.3%) of 12 EBVaGCs and in 51 (47.7%) of 107 non-EBVaGCs, the difference between two groups being not significant. Mean PCNA index was 38.2+-26.1% in EBVaGCs and 22.8 +- 20.0% in non-EBVaGCs. The index was significantly higher in the former than in the latter. CONCLUSION: These results suggested that neoplastic progression in EBVaGCs was implicated with high expression of PCNA, but not consistently with overexpression of p53 protein or LMP-1.
Adenocarcinoma*
;
Epstein-Barr Virus Infections
;
Herpesvirus 4, Human
;
In Situ Hybridization
;
Membrane Proteins
;
Proliferating Cell Nuclear Antigen*
;
RNA
;
Stomach Neoplasms
5.Evaluation of disabled patients with 10 ADLs.
Soon Ho KUEON ; Bang Hoon LEE ; Kang Mok LEE
Journal of the Korean Academy of Rehabilitation Medicine 1991;15(2):48-55
No abstract available.
Activities of Daily Living*
;
Humans
6.Bone Densitometry in Rheumatoid Arthritis
Sang Hoon LEE ; Shin Young KANG ; Jong Seok LEE
The Journal of the Korean Orthopaedic Association 1988;23(3):841-848
Rheumatoid arthritis is considered to be a collagen disease which mainly involves articular structures, sometimes has extraarticular manifestations. It is generally accepted now that periarticular osteoporosis develops in early phase of rheumatoid arthritis and generalized osteoporosis in late period. Of several methods of non-invasive measurement of bone mass, single photon absorptiometry was introduced by Cameron and Sorenson(1963) and it has been used for measuring bone mass by many authors with its precision, reproducibility and objective quantification. We tried to observe the quantitative changes of bone mass in rheumatoid arthritis patients with single photon absorptiometry technique. Through the study of bone densitometry in 30 rheumatoid arthritic women compared with age-matched 60 healthy controls, we obtained follow results. 1. Bone mineral density of the rheumatoid arthritis group was lower than that of the control group, but had no significant statistical difference. 2. Bone mineral density of the 40–49-year-old group and 50–59-year-old group was considerablely different in the rheumatoid arthritis group and control group. 3. Bone mineral density of the group whose rheumatoid arthritis history was over 2 year was lower than that of the group below 2 year.
Absorptiometry, Photon
;
Arthritis, Rheumatoid
;
Bone Density
;
Collagen Diseases
;
Densitometry
;
Female
;
Humans
;
Osteoporosis
7.Molecular genetic study of primary malignant brain tumors:loss of heterozygosity on chromosome 10, 13q, 17q and 22q.
Seung Hoon LEE ; Jong Hyun KIM ; Chang Hoon LEE ; Young Soon KANG ; Je Ho LEE
Journal of the Korean Cancer Association 1993;25(5):717-724
No abstract available.
Brain*
;
Chromosomes, Human, Pair 10*
;
Molecular Biology*
8.A Study on the T Lymphocyte Subsets and Serum IgE in Patients with Atopic Dermatitis.
Seung Joo KANG ; Seon Hoon KIM ; Yoo Shin LEE
Korean Journal of Dermatology 1987;25(2):169-175
This study was undertaken to elucidate any quantitative abnormalities of Tlymphocyte subsets (helper/inducer T cell; T cell and suppressor/cytotoxic T cell: T cell) and IgE levels in the peripheraI blood in atopic dermatitis patients by using monoclonal antibodies and enzyme immunoassay, respectively. In addition we have tried to ascertain whether there are any correlations betveen such immuiiologic abnormalities and the severity of the disease. The results showed that there were significant decrease in the mean percentage of T Cells and increase in the mean value of T/T cell ratios in patients with atopic dermatitis. These changes seem to relate to the severity of the disease when evaluated as groups. A significant increase in the mean value of serum IgE was found in atopic dermatitis patients and the change was related to the severity of the disease. But increase of serum IgE level did not correlated closely with the T cell abnormalities in each patients.
Antibodies, Monoclonal
;
Dermatitis, Atopic*
;
Humans
;
Immunoenzyme Techniques
;
Immunoglobulin E*
;
T-Lymphocyte Subsets*
;
T-Lymphocytes
9.Systemic Lupus Erythematosus Showing Vesiculobullous Eruptions: Report of Two Cases.
Young Jin KOH ; Kwang Hoon LEE ; Won Hyoung KANG
Korean Journal of Dermatology 1986;24(6):853-858
l6-year-old male and 48-year-old female with systemic lupus erythematosus (SLE) and renal disease presented with vesiculobullous eruptions during severe attack of the disease. They showed hypocomplementernia, and high ANA titers. Histopathologic findings revealed subepidermal blister and leukocytoclastic vasculitis, Direct immunofluorescence demonstratedlinear deposits of IgG, IgA and lgM at the dermoepidermal junction. The vesiculobullous eruption of SLE may be an important marker reflecting disease activity and prognosis.
Blister
;
Female
;
Fluorescent Antibody Technique, Direct
;
Humans
;
Immunoglobulin A
;
Immunoglobulin G
;
Lupus Erythematosus, Systemic*
;
Male
;
Middle Aged
;
Prognosis
;
Vasculitis
10.The function of frontal lobe of schizophrenics on the neuropsychological test.
Hyeun Sook KANG ; Sung Hoon LEE ; Eun Sun HAN
Journal of Korean Neuropsychiatric Association 1992;31(2):267-274
No abstract available.
Frontal Lobe*
;
Neuropsychological Tests*