The orthopaedic treatment regarding to the residual deformity secondary to epiphyseal plate injury is the most important thing. Author particularily interested in the microscopic finding upon the repair of damaged transepiphyseal fracture of the distal femoral end of growing rabbits. Experimentally this type of fracture is produced surgically and fixation is achieved by two Kirshner wires; one Kirshner wire is inserted obliquely through the metaphysis. A total of 10 growing rabbits were fed with normal diet, and each 5 rabbits were psacrified by 8 and 10 weeks after the surgical procedure respectively and histological change is examined. No rabbit had infection for those experiment. The results of observation were summarized as follows:1. The ruptured epiphyseal plate due to osteotomy through epiphyseal plate was found to be healed by new bone and fibrotic tissue, not by cartilage regeneration. 2. The epiphyseal plate in the small part of fracture fragments revealed as follows; a. The arrangement of cartilage zones revealed marked irregularity. b. The form and the character of cartilage cells revealed an abnormality such as the hyperophy or the atrophy of cells or both. c. The necrotic area revealed at the several places. d. The thickness of epiphyseal plate revealed more narrowing and irregularity. 3. The effect on the kirschner wires were seen as follows; a. There was no evidence of cartilage regeneration on the margin of the damaged epiphyseal plate. due to Kirschner-wire insertion b. The adjacent tissues around the both kirschner Wires revealed pretty heavy new bone formation.
Atrophy ; Bone Wires ; Cartilage ; Congenital Abnormalities ; Diet ; Femur ; Growth Plate ; Osteogenesis ; Osteotomy ; Rabbits ; Regeneration

A case report on the ABO-type imcompatible transfusion has been made. The case was O-type, 51 year old male who has been transfused 1,000ml of A-type whole blood during and after the intramedullary nailing of the left femur. He had fall in acute hemoglobinuric renal failure immediately after the transfusion. He has been received peritoneal dialysis (P.D.) at eighth day after mismatched transfusion, to correct the uremic condition. His pre-P.D. labaratory findings were Hb. 4.5gm%, BUN 85mg%, creatinine 12. 2mg% and K 7.0mEq/1. He was well recovering after the P.D. but worse again in 16th day after mismatched transfusion with BUN 114mg%, creatinine 12.4mg% and pulmonary edema. An-other P.D. was performed at 16th day and recovered gradually since then. He had marked maximum amount of urine was 9, 100ml at 36 th day after mismatch transfusion. Following the second P.D. his conditions improved gradually and electrolyte imbalance was controlled caused from polyuric state properly. His renal condition was recovered completely at the ten weeks after the mismatch transfusion.
Acute Kidney Injury ; Blood Transfusion ; Creatinine ; Femur ; Fracture Fixation, Intramedullary ; Humans ; Male ; Peritoneal Dialysis ; Pulmonary Edema ; Renal Insufficiency

No abstract available.
Anesthesia* ; Humans

Glomus tumor arises from the subcutaneous glomus body, which is an arteriovenous anastomosis involved in the regulation of cutaneous blood circulation and are widely distributed in the body, especially the hand. Twelve patients (male 3, female 9) with glomus tumors of the hand, who were operated from Jan. 1986 to Dec. 1994 were selected. The lesions were distributed in the distal phalanges of the thumb (6 cases), the index (3 cases), the ring finger (2 cases) and the little finger (1 case). All patients had the classic triad of symtoms: pain, tenderness and temperature sensitivity. Palpable mass (4 cases) and bluish purple discoloration in the skin (6 cases) were also presented. They had no trauma history and on the roentgenography, bone change detected in 2 cases. A simple excision with partial nail extraction was done in all cases. The symtoms were disappeared in all cases and no recurrence was found. For a complete cure, meticulous complete excision is the only recommended treatment.
Arteriovenous Anastomosis ; Blood Circulation ; Female ; Fingers ; Glomus Tumor* ; Hand* ; Humans ; Radiography ; Recurrence ; Skin ; Thumb

Primary pulmonary hemangiopericytoma is a rare, potentially malignant tumor and assumes more malignant course than that originated in the soft tissue. It can be asymtomatic until attaining a large size within the lung. We report a case of malignant hemangiopericytoma of the lung in a 29 year old man. It represented as a sharply demarcated, huge homogeneous opaque mass in the right upper lobe. The cytologic and histologic features were that of malignant hemangiopericytoma.

BACKGROUND: Hemoptysis is a common clinical symptom, responsible for 11% of admission to the hospital chest service. Correct diagnosis, accurate localization of the bleeding source and proper management are imperative to reduce the risk of massive hemoptysis. We performed the study to define the optimal time of fiberoptic bronchoscopy in 63 patients with hemoptysis admitted to Kyung Hee University Hospital between Aug 1989 and Aug1992. METHODS: Retrospective analysis of medical records concerning the cause, amount, duration of hemoptysis and the timing of fiberoptic bronchoscopy in 63(M:F=36:27) patients. RESULTS: 1) The main causes of hemoptysis were pulmonary tuberculosis(52.4%) bronchiectasis(27.0%) and lung cancer(11.1%). 2) The bleeding sites were localized in 26 Patients(41.3%). 3) The rates of localization of bleeding site were not related to the amount and duration of hemoptysis. 4) The rates of localization of bleeding site were 61.8%(21/34) during hemoptysis,18.2%(122) within 24hr after resolution of hemoptysis, 14.3%(1/7) thereafter. CONCLUSION: Early bronchoscopy, especially during hemoptysis may show higher rates of successful localization than delayed bronchoscopy.
Bronchoscopy* ; Diagnosis ; Hemoptysis* ; Hemorrhage* ; Humans ; Lung ; Medical Records ; Retrospective Studies ; Thorax

BACKGROUND: This study was aimed at defining the varying responses of porcine coronary artery(PCA) to various wavelengths of ultraviolet irradiation, and at relating them to the changes in cyclic GMP contents. METHODS: The ring preparations of PCA with intact or removed endothelium were irradiated with the ultraviolet or visible light of wavelengths(240-520mm) from xenon lamp of a spectrofluorometer, and the changes in vascular tension were recorder on polygraph. For cyclic GMP assay, rat thoracic aorta was frozen after irradiation and homogenated. The supernatant was extracted with water-saturated ether and the cyclic GMP contents were measured with radioimmunoassay. RESULTS: Ultraviolet irradiation relaxed the preparations(UVR-relaxation) in resting state and those precontracted by prostaglandin F2alpha, the maximal relaxation occurring at 410nm, and the magnitude depending on the duration of irradiation. The UVR-relaxation was not affected by removing the endothelium, while it was markedly potentiated by pretreatment with Bay K 8644. The Bay K 8644-induced potentiation of UVR-relaxation was abolished by hemoglobin and slightly reduced by wrapping the rings with aluminum foil. Cyclic GMP contents in the increase was markedly potentiated by pretreatment with Bay K 8644. CONCLUSION: The observations suggest that UVR-relaxation in procine coronary artery is caused by activating the nitric oxide-cyclic GMP system, which is most sensitively activated by UVR of 410nm and that its potentiation induced by Bay K 8644 may be related nitrous substance released from the agent upon UVR.
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester* ; Aluminum ; Animals ; Aorta, Thoracic ; Bays* ; Coronary Vessels* ; Cyclic GMP ; Dinoprost ; Endothelium ; Ether ; Light* ; Passive Cutaneous Anaphylaxis ; Radioimmunoassay ; Rats ; Relaxation* ; Ultraviolet Rays ; Vasodilation ; Xenon

Granular cell tumor is not uncommon and is a well recognized entity which may arise at virtually any site of the body. However, occurrence in the thyroid is extremely rare and has not been described well. Only three cases could be found in the English literatures. We report a case of granular cell tumor of the thyroid in a 30 year-old woman. The tumor was illdefined, infiltrative and was composed of diffuse sheets of polygonal to fusiform cells with abundant eosinophilic granular cytoplasm. The tumor showed evidence of Schwann cell differentiation in immunohistochemical and ultrastructural examinations. Differentiation from more common thyroid tumors having oncocytic granular cytoplasm should be made by immunohistochemistry or electron microscopy.
Adult ; Cell Differentiation ; Cytoplasm ; Eosinophils ; Female ; Granular Cell Tumor* ; Humans ; Immunohistochemistry ; Microscopy, Electron ; Thyroid Gland*

No abstract available.
Follow-Up Studies* ; Prostheses and Implants*

No abstract available.
Blood Cells* ; Leukemia*