As an attempt to evaluate the influence of various external factors to the formation of urinary stone, age, sex, resident area, level of education, smoking, daily amount of water drinking and past history of all patients admitted to the Department of Urology, Severance Hospital, Yonsei Univereity, from November, 1970 to October, 1971 were studied according to the designed questionaires. Prevalence rates of urinary stone cases were obtained against total number of patients admitted by the various epidemiological factors. The results are summarized briefly as follows: 1. Prevalence rate of the urinary stone by sex was somewhat higher in female than in male. 2. Urinary stone was most prevalent in the age of 21~40 and bladder stones were seen in the middle and older age groups among male 3. The hot weather from July to October showed the highest rates in prevalence and the cold weather from December to March showed the lowest prevalence rates. 4. Urinary stone was more prevalent among intellectuals or among high level of education. 5. Urinary stones were more prevalent among residents in the large city than the residents in the middle city or rural area. 6. Smoking seemed to be not related to the stone formation. 7. The prevalence rate of urinary stone was related to the water drinking. 8. Patient with history of immobilization had more prevalence rate than those without history of immobilization.
Drinking ; Education ; Epidemiologic Studies* ; Epidemiology ; Female ; Humans ; Immobilization ; Male ; Prevalence ; Smoke ; Smoking ; Urinary Bladder Calculi ; Urinary Calculi* ; Urology ; Water ; Weather

No abstract available.
Child* ; Diagnosis* ; Humans ; Urinary Tract Infections* ; Urinary Tract*

In the previous review, the physical aspect of heavy particles, with a focus on the carbon beam was introduced. Particle beam therapy has many potential advantages for cancer treatment without increasing severe side effects in normal tissue, these kinds of radiation have different biologic characteristics and have advantages over using conventional photon beam radiation during treatment. The relative biological effectiveness (RBE) is used for many biological, clinical endpoints among different radiation types and is the only convenient way to transfer the clinical experience in radiotherapy with photons to another type of radiation therapy. However, the RBE varies dependent on the energy of the beam, the fractionation, cell types, oxygenation status, and the biological endpoint studied. Thus this review describes the concerns about RBE related to particle beam to increase interests of the Korean radiation oncologists' society.
Carbon ; Cell Fractionation ; Oxygen ; Photons ; Population Characteristics ; Protons ; Relative Biological Effectiveness

BACKGROUND: Ultraviolet light induces sunburn, ageing of the skin, pigmentation and even promotes skin cancers. As there has been a recent decrease in the ozone layer surrounding the earth, increasing attention has been given to the effects of ultraviolet light on the skin. Through human epidermis, ultraviolet light is reflected, scattered, absorbed or transmitted. In caucacians, the rate of transmitted ultraviolet light A from the epidermis to the dermis is 50% and the rate of transmitted ultraviolet light B is below 10%. OBJECTIVE: The purpose of this study was to evaluate the transmittance of UVA and UVB on Korean normal epidermis. METHODS: Pure epidermis was obtained from normal human epidermis by suction of blisters in 12 patients with vitiligo. All specimens were irradiated respectively with UVA and UVB and the amount of transmitted energy was measured. RESULTS: 1. The transmittance of UVA energy density by normal epidermis was 47.7+11.2% of irradiated UVA energy. 2. The transmittance of UVB energy density by normal epidermis was 32.4+3.4% of irradiated UVB energy. CONCLUSION: UVA energy transmission through normal epidermis of Korean is less than those of Caucacians but UVB energy transmission through nor mal epidermis of Korean is more than those of Caucacians. It is suggested that this could be an important basic data to study for photoaging and photoprotection in Korean population.
Blister ; Dermis ; Epidermis* ; Humans* ; Pigmentation ; Skin ; Skin Neoplasms ; Stratospheric Ozone ; Suction ; Sunburn ; Ultraviolet Rays ; Vitiligo

No Abstract available.

BACKGROUND: The relationship and differentiation among various dendritic cells of the dermis are unclear. Recently it has hecome possible to identify different subpopulat,ions of dermal dendritic cells using anti-CD34 and anti-factor XIIIa antibodies. OBJECTIVE: To elucidate which cell types the fibrous dermal turnors consist of we compared the staining patterns of these antibodies as well as of anti-Mac 387 antibody which are labeled as inflammatory cells of the monocyte-macrophage lineage. METHODS: Tumors studied included dermatofibrosarcoma protuberans(DFSP, n=2), dermato-fibroma(n=22), neurofibroma, n=27), acrochordon(n=15), keloid, hypertrophic scar(n=10), juvenile xanthogranuloma(n=1, and malignant fibrous histiocytoma (MFH, n=1). We performed immunoperoxidase staining(AUSC technique) with polyclonal anti FXIIIa antibody, monoclonal anti-CD34 antibody, and monoclonal anti-Mac 387 antibody on the formalin-fixed-paraffin-embedded tissue specimens of these fibrous tumors. The intensity of staining was graded as negative, weakly staining, or strongly stainiring. RESULTS: FXIIIa reactivity was strongly present in dendritic and spindle-shaped cells of all dermatofibromas and some nurofibromas(11 of 27 specimens), but absent from the other fibrous tumors. Among these tumors, one of the two DFSPs was uniquely expressed CD34. Dendritic and spindle-shaped cells within tiese tumors were MAC 387 negative. In inflammatory conditions, variable numbers of MAC 38 positive cells were observed, corresponding to histiocytes and mac-rophages, but the labeling of ipithelioid cells and multinucleated foreign body giant cells were variable. CONCLUSION: The findings of significant numbers of FXIIIa positive cells in dermal fibrous tumors studied suggest that thet may be diagnostic utility associated with the use of this antit)ody. In addition, CD 34 expression by the tumor cells can be an extremely useful marker in establishing a definitive diagnosis of IFSP.
Antibodies ; Dendritic Cells ; Dermatofibrosarcoma ; Dermis ; Diagnosis ; Factor XIIIa* ; Giant Cells, Foreign-Body ; Histiocytes ; Histiocytoma, Benign Fibrous ; Histiocytoma, Malignant Fibrous ; Keloid ; Langerhans Cells ; Neurofibroma

This study demonstrates that prophylactic effect of plaster and cataplasm contained ketoprofen in adjuvant arthritis therapy by X-ray. Adjuvant arthritis was induced by a single injection of Freund's complete adjuvant. Mature female Sprague-Dawley rats were designated to 3 groups such as nontreated control, plaster-treated (PT) and cataplasm-treated (CT), each of which was composed of ten animals. The PT and the CT groups showed reduced primary paw swelling, but secondary paw swelling was not affected. Bony changes were observed in all regions of the femur and tibia of the nonadjuvant-injected leg and the adjuvant-injected leg. The mean radiographic scores of the PT and the CT groups were significantly lower than those of the control group from day 0 to 7 of the experimental period (p<0.05, p<0.01). The CT rats showed reduced poly-arthritis development than the PT rats. Our results suggest that radiographic assessment of bony changes is more suitable for measuring changes in long bones such as femur or tibia than in vertebrae. The prophylactic effect of CT prominently suppressed edematous swelling and bony changes in arthritic limb compared with PT.
Animals ; Anti-Inflammatory Agents, Non-Steroidal/*pharmacology ; Arthritis, Experimental/*prevention & control ; Calcium Sulfate ; Drug Carriers/administration & dosage ; Excipients/*administration & dosage ; Female ; Freund's Adjuvant ; Ketoprofen/*administration & dosage/analogs & derivatives/therapeutic use ; Rats ; Rats, Sprague-Dawley

Diffuse alveolar hemorrhage (DAH) is an uncommon complication in patients with systemic lupus erythematosus (SLE), and mortality remains high. In recent years, cases of DAH due to SLE treated with extracorporeal membrane oxygenation (ECMO) have rarely been reported. The authors present a case of a 43-year-old woman with SLE who had rapidly aggravating dyspnea and hemoptysis. She was diagnosed as having DAH with refractory respiratory failure and was successfully managed with veno-venous ECMO. We propose ECMO as a useful salvage therapy in patients with alveolar hemorrhage secondary to SLE who are failing conventional ventilatory support.
Adult ; Dyspnea ; Extracorporeal Membrane Oxygenation* ; Female ; Hemoptysis ; Hemorrhage* ; Humans ; Lupus Erythematosus, Systemic* ; Mortality ; Respiratory Distress Syndrome, Adult ; Respiratory Insufficiency ; Salvage Therapy

Pelvic Bones* ; Sex Differentiation*

The usefulness of two-dimensional echocardiography to measure the right ventricular volume was assessed in 58 normal children (mean age 5 years and 3 months). From the apical 4-chamber view (A4CV), the subcostal RV sagittal view (SCRVSV), the subcostal right anterior oblique view (SCRAOV), and the subcostal RV coronal view (SCRVCV), the dimensions and areas of the right ventricle were measured. The right ventricular volumes and ejection fractions were calculated from these data by pyramid model and single plane area/length method. We could obtain subcostal right ventricular sagittal view in 98%, apical 4-chamber view in 90%, subcostal right anterior oblique view in 79%, and subcostal right ventricular coronal view in 71% of our children. The areas and dimensions correlated with all growth indices, such as age, height, weight, and body surface area. In general the areas showed higher correlation with body surface area, and dimensions with height. correlations of parameters obtained from the subcostal right anterior oblique view and subcostal right ventricular sagittal view with the growth indices were better than those of the subcostal right ventricular coronal view. The calculated right ventricular volume and ejection fraction showed a great varibility depending on the model used. The right ventricular volume calculated by pyramid model correlated better with the growth indices than that by single plane area/length method. the right ventricular volume calculated from the apical 4-chamber view dimension and the subcostal right ventricular sagittal view area by pyramid model is the model which showed the best correlation with growth indices. Right ventricular ejection fraction did not change with any growth indices. Among the right ventricular volumes and ejection fractions by single plane area/length method, the volume(59.9+/-29.9 ml/m(2)) and ejection fracton (58.7+/-10.9%) from the subcostal right anterior oblique view were similar to those (51.0+/-17.3ml/m(2), 51.3+/-10.2%) calculated from the apical 4-chamber view dimension and the subcostal right ventricular sagittal view area by pyramid model. The subcostal right anterior oblique view reflects three parts of the right ventricle. Its area and dimension are well correlated with growth indices. Also the right ventricular volume and ejection fraction obtained by single plane area/length method using the subcostal right anterior oblique view correlate with the growth indices. Therefore the subcostal right anterior oblique view is the most valuable single view representing the right ventricle.
Body Surface Area ; Child* ; Echocardiography* ; Heart Ventricles ; Humans ; Stroke Volume