Fixed assets management is an important part of hospital operation management. At present, the fixed asset management of public hospitals in China lacks integrity and needs further improvement. In May 2022, a tertiary public hospital in Shanghai explored a fixed asset bubble management mode from an integrated perspective based on a bubble management strategy. The main approach included building a hospital′s fixed asset management organizational structure, equipping it with fixed asset sorting cards, setting up large, medium and small fixed asset bubbles respectively, implementing such management measures as bubble flow management, bubble rupture plans, and bubble internal and external environmental risk control mechanisms.In March 2023, the hospital had constructed 104 fixed asset management bubbles, including 17 large bubbles, 58 medium bubbles and 29 small bubbles. The fixed asset bubble management mode effectively reduced the loss rate of hospital fixed assets and achieved a preliminary success, providing reference for improving the efficiency and quality of fixed asset management in public hospitals in China.