1.A Survey on the Use of External Medications and Injection Drugs Conducted by Persons Visiting in a Health Insurance Pharmacy
Kana HASHIMOTO ; Narumi TOYA ; Mihee PARK ; Akihiko IKEMOTO ; Hirohumi OHNISHI ; Masahiro MURAKAMI ; Masako OHNO ; Manabu AMANO
Japanese Journal of Social Pharmacy 2018;37(2):102-108
Since attention is sometimes required with regard to the use and handling of external medications or injection drugs in drug therapy, patients may have a feeling of “inconvenience”. We, therefore, focused on a feeling of “inconvenience when using” external medications and injection drugs, and conducted a questionnaire survey to investigate the level of awareness and current status of using assist devices that can effectively reduce such inconvenience. The survey took place at a pharmacy, and involved interviews using a questionnaire. Of the 197 respondents, valid responses were obtained from 147 individuals (74.6%). As the results, 25.9% of individuals using external medications or injection drugs responded ‘yes’ concerning the feeling of “inconvenience when using” them. In addition, 39.4% of individuals using eye drops and 10.5% of those using insulin similarly responded. However, only 10.9% knew of the availability of assist devices that are expected to reduce the inconvenience. The results revealed that a certain number of people feel the “inconvenience” of external dosage forms investigated in this study, suggesting the need for pharmacists to consider that patients may have problems using their medications, and to recommend and support the use of assist devices that can be operated by patients.
2.Analysis of Awareness and Perception Alteration of Simple Suspension Method by a Workshop for Hospital Pharmacists
Kana HASHIMOTO ; Yoshiko TAKAHASHI ; Hiroshi SUZUKI ; Takeshi KIMURA ; Atsushi KINOSHITA ; Tadashi SHIMIZU ; Manabu AMANO
Japanese Journal of Social Pharmacy 2021;40(1):50-58
The conventional crushing method for administration of drugs to patients with feeding tubes has been commonly used at the Hyogo College of Medicine College Hospital. Compared with this conventional method, the simple suspension method can reduce drug degradation due to light and moisture absorption as well as avoid drug loss and contamination. We conducted a workshop to introduce this method to pharmacists. We asked the participants to fill a questionnaire-based survey both before and after the workshop to determine the effects of the workshop on the change in the degree of awareness among participants about these methods. The awareness of participants about the simple suspension method was approximately 80% before the workshop. Approximately 60% of participants answered that they had questions about simple suspension method from individuals from other occupations, suggesting a high awareness of this method. After the workshop, approximately 98% of participants answered that they were “satisfied” or “slightly satisfied,” suggesting that they were in favor of introducing the suspension method. The results of text mining indicated a requirement for participants to consider incompatibilities and to educate the nursing department. Participants who actively considered the proposal of simple suspension method had an altered perception toward the introduction and utilization of this method. Therefore, this survey suggested that workshops could alter the perception and behavior of pharmacists about the methods of drug administration via feeding tube.
3.A Survey on the Use of External Medications and Injection Drugs Conducted by Persons Visiting in a Health Insurance Pharmacy
Kana HASHIMOTO ; Narumi TOYA ; Mihee PARK ; Akihiko IKEMOTO ; Hirohumi OHNISHI ; Masahiro MURAKAMI ; Masako OHNO ; Manabu AMANO
Japanese Journal of Social Pharmacy 2018;37(2):102-108
Since attention is sometimes required with regard to the use and handling of external medications or injection drugs in drug therapy, patients may have a feeling of “inconvenience”. We, therefore, focused on a feeling of “inconvenience when using” external medications and injection drugs, and conducted a questionnaire survey to investigate the level of awareness and current status of using assist devices that can effectively reduce such inconvenience. The survey took place at a pharmacy, and involved interviews using a questionnaire. Of the 197 respondents, valid responses were obtained from 147 individuals (74.6%). As the results, 25.9% of individuals using external medications or injection drugs responded ‘yes’ concerning the feeling of “inconvenience when using” them. In addition, 39.4% of individuals using eye drops and 10.5% of those using insulin similarly responded. However, only 10.9% knew of the availability of assist devices that are expected to reduce the inconvenience. The results revealed that a certain number of people feel the “inconvenience” of external dosage forms investigated in this study, suggesting the need for pharmacists to consider that patients may have problems using their medications, and to recommend and support the use of assist devices that can be operated by patients.
4.The albumin to globulin ratio is associated with clinical outcome in Japanese patients with ulcerative colitis
Sen YAGI ; Shinya FURUKAWA ; Kana SHIRAISHI ; Teruki MIYAKE ; Kazuhiro TANGE ; Yu HASHIMOTO ; Shogo KITAHATA ; Tomoe KAWAMURA ; Tomoyuki NINOMIYA ; Kenichirou MORI ; Seiyuu SUZUKI ; Naozumi SHIBATA ; Hidehiro MURAKAMI ; Katsuhisa OHASHI ; Aki HASEBE ; Hideomi TOMIDA ; Yasunori YAMAMOTO ; Eiji TAKESHITA ; Yoshio IKEDA ; Yoichi HIASA
Annals of Coloproctology 2023;39(2):155-163
Purpose:
The albumin-to-globulin ratio (AGR) is a recognized chronic inflammation marker. No evidence regarding the relationship between AGR level and ulcerative colitis (UC) exists. The aim of this study was to evaluate the association between AGR and clinical outcomes among Japanese subjects with UC.
Methods:
The study subjects consisted of 273 Japanese individuals with UC. AGR was divided into 4 categories (low, moderate, high, and very high). The definition of complete mucosal healing (MH) was based on the Mayo endoscopic subscore of 0. Clinical remission (CR) was defined as no rectal bleeding and no abnormally high stool frequency (<3 times per day).
Results:
The percentage of MH was 26.4%. High AGR and very high AGR were significantly positively correlated with CR (adjusted odds ratio [OR], 5.85; 95% confidence interval [CI], 2.52–14.18 and adjusted OR, 4.97; 95% CI, 2.14–12.04) and complete MH (adjusted OR, 4.03; 95% CI, 1.56–11.51 and adjusted OR, 5.22; 95% CI, 1.97–14.89), respectively after adjustment for confounding factors (P for trend=0.001). Only in the low C-reactive protein (CRP) group (≤0.1 mg/dL), very high AGR was significantly positively correlated with complete MH but not CR (adjusted OR, 4.38; 95% CI, 1.06–21.77; P for trend=0.017). In the high CRP group, no correlation between AGR and complete MH was found.
Conclusion
Among Japanese patients with UC, AGR may be independently positively correlated with complete MH. In particular, among UC patients with low CRP, AGR might be a useful complementary marker for complete MH.