Objective To investigate plasma soluble intercellular adhesion molecule-1 ( sICAM-1) concentration in women with polycystic ovary syndrome (pcos)and their clinic significance. Methods The level of sICAM-1 in serum in 41 patients with pcos and in 39 healthy persons were measured by ELASA.The possible relationship between sICAM-1 and clinical materials were analyzed by multiple linear regression analysis.Results ①The sICAM-1level in women with PCOS was higher than of that healthy persons(P