Objective To master the characteristics of the outbreak of diarrhea,so as to provide evidences for formulat-ing the measures of control and prevention. Methods Epidemiological data and laboratory data of registered patients were investigated,and descriptive epidemiological method was applied to statistically analyze the data. Results A total of 235 patients were infected, and the morbidity rate was 7.66%. Morbidity rate in cooks was significantly higher than that in students, teaching staff and family members, males higher than females, and on-campus students higher than off-campus students; the water plant supplied drinking water not conforming to the standard of hygiene,and the cooks were not detected timely and transferred from the current position after being infected with bacillary dysentery and di-arrhea. The bacteria was transmitted via water and food,combined with the transmission via intimate contact and carri-ers by flies. Conclusion Management on the hygiene of food and drinking water in the school should be strengthened,environment disinfection and insecticide should be carried out,and the population in epidemic focus of diarrhea should be orally given norfloxacin for prevention; the supervising mechanism of infectious diseases in the school is estab-lished,potential safety hazard is timely dealt with,and water-borne communicable diseases can be prevented.