Objective To understanding the distribution and variation of children zinc level in Kaifeng to provide guid-ance for the prevention of children's lack of trace elements. Methods All 2054 cases of healthy children aged 0 month to 6 years old were randomly sampled in 2014 in the region, among which 1205 cases were male and 849 cases were female. Their Zinc levels were tested with atomic absorption spectrometry. Results Peripheral blood zinc levels of the boys and girls in 2014 was positively related to age (P<0.01), and there were no significant gender differences in the same age group (P>0.05). The overall deficiency rate was 26.5% in the sample and was similar among different age groups. Conclusion As people become more aware of the need of prenatal and postnatal care and have deeper under-standing of zinc, zinc deficiency rate in children has decreased. However, the rate is still high among preschoolers. At-tention should be paid to promote balanced diet among them to increase zinc supplement and absorption.