1.INITIAL USE OF MONOCLONAL ANTIBODIES (McAbs) FOR THE TYPING OF ACUTE NON-LyMPHOID I.EUKEMIA(ANLL) AND CHRONIC MyELOCyTIC LEUKEMIA(CML)
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(04):-
The leukemic cellular surface antigens of 45 cases for ANLL and 36 cases of CML were detected and classified with a series of the domestic McAbs by immunoflurescent technique. The immunophenotype of ANLL was compared with its cellular morphologic classification. The difference of the surface antigens between the CML instable phase and the CML in blast crisis was analyzed. Four cases of acute leukemias (AL) which could not be classified morphologically were classified by McAbs. FAB M_1~M_5 could be divided into 3 phenotype groups: myeloblastic, promylocytic and promoncytic phenotype. The immunophenotype of ANLL tended to agree with its cellular morphologic classification. All 28 cases of CML in stable phase reacted with a neutrophil-McAb. However, there was no this antigen expression in 8 cases of CML in blast crisis. The immunophenotype of 4 cases of AL could be made with McAbs . Of these 4 cases. 3 were AL and 1 ANLL.
2.Construction of the assessment index system for department general nursing goals management
Ying CUI ; Ling GUO ; Kaijun HAO ; Xiaoning ZHANG ; Kefang WANG
Chinese Journal of Practical Nursing 2017;33(6):458-465
Objective To construct the assessment index system for general nursing goals management based on the performance structure theory. Methods Expert interviews and Delphi expert enquiry were used to complete the construction of index system, and SPSS17.0 was used to do data statistics and reliability analysis. Results The assessment index system for general nursing goals management was constructed which contained 6 level-Ⅰindicators such as nursing quality, nursing safety, nursing service, teaching and training, the contribution of department and the communication skills and 22 level- Ⅱ indicators. The department monthly examination scores calculation method and feedback mechanism were also established. The expert positive coefficients were 97.6%and 98.8%respectively, the authority coefficients were 0.85 and 0.86, the importance and feasibility mean scores of every index were 3.86-4.98 and 3.98-4.88, and coefficients of variation were 0.03-0.27 and 0.05-0.25 in 2 rounds of enquiry. The importance of level-Ⅰor level-Ⅱ indicators and operability coordination coefficients were 0.10-0.36, the significance test showed P<0.05. Conclusions The design of each dimension of the index system gives full consideration to 3 dimensions of performance: task-adaptive-relationship. Representative of key indicators is strong. The Delphi method used in building is scientific and the results are reliable. The maneuverability of calculate Method is strong, easy to quantify. The feedback mechanism has a strong incentive by combining the assessment results closely with the individual interests. The establishment of the index system can provide scientific and objective basis for the full implementation of the general nursing goals management.
3.Relationship between serum uric acid and dietary patterns in Tianjin residents
Li LIU ; Qing ZHANG ; Kun SONG ; Xiaoyan GONG ; Jing CUI ; Ying GAO ; Kaijun NIU
Chinese Journal of Health Management 2017;11(1):40-46
Objective To investigate the relationships between different dietary patterns and serum uric acid in Tianjin residents. Method By cross-sectional study design, 11282 subjects were studied via lifestyle questionnaires (including a valid food frequency questionnaire), physical examination and laboratory tests. Using factor analysis method to establish the dietary patterns, and relationships between different dietary patterns and serum uric acid were analyzed. Results Factor analysis showed 3 kinds of dietary patterns, including eastern dietary pattern, vegetable diets and Tianjin dietary pattern. There were more males in hyperuricemic population, who have a higher BMI, waist circumference, blood lipids, blood pressure and blood sugar levels, and also higher proportion of metabolic syndrome, smokers and alcohol drinkers. In addition, hyperuricemia patients had a higher level of social status and income. After adjustments for age, sex, BMI, smoking habits, alcohol consumption, hypertension, hyperlipidemia, education level, occupational status, energy intake, physical activity and metabolic syndrome, logistic regression analysis showed the odds ratio (95%confidence interval) for hyperuricemia across the quartiles of 3 dietary patterns as follows: 1.00, 1.07 (0.91, 1.25), 0.96 (0.82, 1.14), 1.12 (0.94, 1.33);1.00, 1.03 (0.88, 1.21), 1.04 (0.88, 1.23), 1.00 (0.84, 1.19); 1.00, 1.28 (1.08, 1.52), 1.40 (1.22, 1.71), 1.37 (1.15, 1.63), respectively. Significantly positive correlation was shown between Tianjin dietary pattern and hyperuricemia. Conclusion Tianjin residents' Tianjin dietary pattern is closely related to serum uric acid levels. Tianjin dietary patterns have characteristics of high calorie, high fat, high protein. Healthy eating habits have significant importance to prevent occurrence of hyperuricemia.