Objective To explore the effects of music therapy combined with acupuncture and auricular acupoint pressing in childbirth of primipara. Methods From June to December 2017,this study selected 90 primiparas with childbirth in Obstetrics Department at Zhejiang University Zhoushan Hospital as subjects by convenience sampling. All of primiparas were divided into intervention group and control group with the method of random number table,45 cases in each group. Control group adopted music therapy in which patients listened to their favorite music. On the basis of that in control group,intervention group carried out the acupuncture and auricular acupoint pressing. This study compared the Numerical Rating Scale(NRS),the time when the orifice of uterus ranged from 3 to 10 cm,neonatal Apgar score and blood loss two hours after childbirth of delivery women. Results There was no statistical difference in the score of NRS of primiparas between two groups when the orifice of uterus ≥3 cm(P>0.05). The scores of NRS of intervention group were lower than those of control group with statistical differences 30 min after analgesia and when uterus opened to the full(P<0.05). The time when the orifice of uterus ranged from 3 to 10 cm in intervention group was shorter than that in control group with a statistical difference(P< 0.05). There were no statistical differences in the neonatal Apgar score and blood loss two hours after childbirth of patients between two groups(P> 0.05). Conclusions Music therapy combined with acupuncture and auricular acupoint pressing can ease the labor pain,shorten the time when uterus opens to the full,and is safe for mother and baby and has better effects compared with simply music therapy which is worthy of being popularized and applied.