Objective To verify the pattern characteristics of optical coherance tomography (OCT) images in diabetic maculopathy (DM). Methods OCT were performed in sixty cases of DM and 30 cases of normal control group,and in 54 cases of DM,fundus fluorescein angiography (FFA) was performed simutaneously.The results from 2 kinds of examinations were compared each other. Results The average retinal thickness at the central fovea was (314.54?154.13) ?m in DM group.The macular edema in the cases of DM accounted to 57.1% on OCT examination The rate of retinal swelling associated with cystoid macular edema (CME) was 38.5%,with retinal detachment (RD) 9.2%,and with both CME and RD was 16.9% Those with mormal macular thickness and mild macular edema primarily showed focal leakage in FFA exam,while those with moderate and severe macular edema showed diffuse leakage in FFA exam.The rate of CME was 28.6% presented in FFA and 58.9% in OCT examination (t=3.39,P

Objective To verifying the characteristics of optical coherence tomography(OCT) in exudative age related macular degeneration (AMD). Methods The patients being investigated in this series included 16 cases (19 eyes) of exudative age related macular degeneration diagnosed by FFA and OCT examinations, among them 4 cases (6 eyes) were examined with ICGA. The color photographs of ocular fundi, FFA, ICGA and OCT were investigated by contrasting each other. Results As compared with the FFA and ICGA examinations, the characteristic findings found in OCT in patients with exudative AMD in this series were as the following:①serous detachment of neurosensory epithelium in 11 eyes,②retinal hemorrhage in 2 eyes,③serous detachment of retinal pigment epithelium in 5 eyes,④hemorrhagic detachment of retinal pigment epithelium in 10 eyes,⑤disciform scar in 4 eyes,⑥fibrovascular pigment epithelial detachment and occult CNV in 12 eyes. Conclusion OCT can supply a comprehensive survey of exudative AMD, in making the diagnosis as an important complementary examination of FFA and ICGA.

Objective To investigate whether the patients of stroke in basal ganglia have the selective deficit of recognition of disgust expression and to test the hypothesis that basal ganglia is involved in emotion processing, especially in disgust processing. Methods We developed six typical facial emotions (happiness, surprise, fear, sadness, disgust and anger) and a neutral facial emotion. A labeling task with these emotional faces measured the ability to recognize emotional faces in 32 stroke patients in basal ganglia and in 30 normal controls.Results Compared with normal controls, patients of stroke in basal ganglia impaired in perception of facial emotion (correct identification scores, 106.73?7.62, P

Objective To investigate the effects of Hedan tablet on serum adipocytokines and inflammatory factors in rats with metabolic syndrome.Methods The 24-rat model of metabolic syndrome were randomly divided into three groups(n=8,each):normal group were given normal diet,model group were given high-lipid and high-salt diet and intervention group were given high lipid and high salt dict plus Hedan tablet 6.0 g · kg-1 · d-1 by intragastric administration for 3 weeks.Body weight,blood pressure,blood levels of glucose,lipid,leptin,visfatin,adiponectin and CRP were measured in all rats at the beginning and the end of the study.Results Compared with normal group,model group (model versus normal) showed significantly increased serum levels (P ＜ 0.05) of weight,total cholesterol(TC),triglyceride (TG),low-density lipoprotein cholesterol (LDL-C),glucose,leptin(5.5±0.1 vs.5.2±0.0 mmol/L),visfatin(17.5±0.5 vs.16.6±0.0 mmol/L and CRP(1 676.6 ± 74.8 vs.1 642.3 ± 52.2 mmol/L),and showed significantly decreased (P ＜ 0.05) serum level of adiponectin(74.6±2.4 vs.81.3±2.1 mmol/L).Compared with 20 weeks of age group,the 23 weeks of age group(23 weeks versus 20 weeks)showed significantly decreased levels of weight,TC,TG,LDL-C,serum leptin(5.4±0.1 mmol/L vs.5.9±0.2 mmol/L),visfatin(16.7±0.4 mmol/L vs.17.7±0.6 mmol/L)and CRP(1 498.8±51.0 mmol/L vs.1 682.1±76.6 mmol/L(all P＜0.05),and showed significantly increased serum adiponectin level(81.2±3.0 mmol/L vs.73.9±3.1 mmol/L)(P＜0.05).But there was no significant change in model group between 20 weeks and 23 weeks of age.Conclusions Hedan tablet reduces the body weight and ameliorates blood lipid level in rats with metabolic syndrome.These effects may be related to regulation of Hedan tablet on adipocytokines and inflammatory factors.

Objective To study the preventive and therapeutic effect of dexamethasone on communicating hydrocephalus following subarachnoid hemorrhage (SAH), and explore the mechanism of communicating hydrocephalus following SAH. Methods SAH rat model was constructed by injecting auto blood through foramen magnum into subarachnoid space. There were two groups ( one control group and one experimental group) in this study with 16 rats each group. Sufficient doses of auto blood were injected into subarachnoid space of the rats of the control group and sufficient dose of auto blood together with sufficient dose of dexamethasone into subarachnoid space of the rats of the experimental group. The changes of rats transforming growth factor bata-1 (TGF-β_1 )in the cerebrospinal fluid (CSF)and thickness of pia mater collagen fibrosis( CF) following SAH were observed after 1 day and 20 days. The levels of TGF-β_1, in the CSF were quantitatively detected by the way of ABC-ELISA. The brain tissues were dyed through Massions technique, and then the average thicknesses of meningina CF were measured by the software of micrograph collection and analysis computer system. Results In later stage after SAH, TGF-β_1, concentrations of the experimental group was lower than control group( P <0. 01). At the same time, the average thicknesses of meningina CF of experimental groups was thinner than control group( P <0. 01). Moreover, the relationship between the level of TGF-β_1 in the CSF and the thickness of the CF of the rat's cerebral pia mate had positive correlation. Conclusions In the later stage after SAH, dexamethasone can inhibit the over expression of TGF-β_1 in rat CSF following SAH and also can inhibit the accrementition of rat collagenous fibers. Therefore, this study provided experimental and theoretical evidence for preventing and treating communicating hydrocephalus following SAH.

Objective To predict the length of peripherally inserted central venous catheters(PICC) with electronic chest radiograph scale measurement techniques, and observe its clinical effect. Methods A total of 185 breast cancer patients from October 2012 to December 2013 who were treated by PICC combined with MST guided by ultrasonic technology were as control group. A total of 192 breast cancer patients from January to November 2014 were as observation group. Control group adopted from the puncture point to right sternoclavicular joints impreaaion nip down again to the third floor of PICC in vitro measurement method. Observation group used to right sternoclavicular joints from the puncture point plus right sternoclavicular joints to subcarinal 1 vertebral body length, right sternoclavicular joints to subcarinal 1 vertebral body length measurement by electronic chest radiograph scale technology directly measured from the electronic chest radiographs. The accuracy rates and complications between the two measurement methods were compared. Results The accuracy rate in observation group was 97.92%(188/192), which was higher than that in control group (68.11%,126/185 ),and there was significant differencek,χ2=60.15, P<0.01. The complication rate in observation group was 6.77%(13/192), which was lower than that in control group (20.54%, 38/185) ,and there was significant difference,χ2=9.58, P<0.01. Conclusions The electronic chest radiograph scale measurement techniques could effectively improve the accuracy of PICC catheter placed, improve the quality of venipuncture, decrease the complications .

Super-selective transcatheter prostatic arterial embolization is a newly-developed minimally invasive treatment for benign prostatic hyperplasia with good maneuverability, safety and fewer complications. The short-term and mid-term follow-up has proved that it has higher clinical efficacy in improving the quality of life by alleviating lower urinary tract symptoms. It emerges as an innovative technology in urology and interventional radiology. In order to ensure a successful procedure with satisfactory clinical outcome the most important considerations when performing prostatic arterial embolization are to precisely identify the prostatic artery, to correctly differentiate the anastomoses with surrounding arteries, and to properly select embolic agents. This paper aims to make a comprehensive review on the progress and current situation of prostatic arterial embolization with a focus on the clinical issues and technical challenges.

The acetabular fractures are technically challenging due to the deep location in the pelvis and low degree of exposure.Although the classic ilioinguinal approach could treat most anterior acetabulum fractures,the limited surgical field and difficulty in exposure is the main obstacle surgeons should overcome.Various approaches including extended approaches and combined anterior and posterior approaches ensure adequate exposure,but high rate of complications impede it from clinical use.The Stoppa approach has been favored by the orthopedic surgeons in recent years for the minimized surgical dissection and good exposure.It allows for extensive visualization of the pelvic brim and direct manipulation of quadrilateral plate.This approach is indicated in all anterior column and wall fractures,combined anterior column and posterior hemi-transverse fractures,selected both-column fractures,transverse and T-fractures.The utilization of the Stoppa approach developed along with the evolution of the relevant theory of acetabular fractures in the past years.The development such as the precise measurement of “safe zone” and the application of new apparatus could do great help in decreasing the complications and improving the surgical results.This article summarizes the relevant literatures and provides a review of the advances in the Stoppa approach in acetabular fractures.

The expression and possible role of integrin-focal adhesion kinase signal pathway in invasive pituitary adenomas were explored. Forty-nine human pituitary adenomas were detected for the expression of integrinbeta1 (INTbeta1) and focal adhesion kinase (FAK) by immunohistochemistry, and their correlation with the invasiveness of pituitary adenomas as well as between themselves was analyzed. The results showed that INTbeta1 was expressed in 46 cases (93.9%) and FAK in 36 cases (73.5%), respectively, and their expression levels were highly correlated with tumor invasiveness, but not with the tumor types. It was suggested that the integrin-focal adhesion kinase signal pathway plays a role in the invasiveness of pituitary adenomas.