Objective:To make animal model of chronic heart failure(CHF)resulting from pressure overload in juvenile rats,and discuss its pathophysiology.Methods:The animal model of CHF was established by constriction of abdominal aorta.After four weeks of operation,the high frequency ultrasonography,the hemodynamic study,the pathologic analysis of hearts were undergone,the cardiac myocyte apoptosis,and serum contents of lipid peroxidation(LPO) and superoxide dismutase(SOD) were investigated.Results:Compared with the sham-operated group,inner diameter,wall thickness of left ventricule,LVRW,RVRW,SBP,DBP,LVSP,LVEDP,AI,LPO increased significantly( P

BACKGROUND: Studies concerning trunk muscles mainly focus on muscle strength changes in patients with low back pain,which is rare regarding angle ranges that easily lead,to spinal injury.OBJECTIVE: To explore the mechanics characteristic of flexor-extensor and angle ranges easily lead to spinal injury. METHODS: Fourteen healthy, male, post-graduates of Soochow University were selected. Flexor-extensor strength and spinal angle of participants were measured using CON-TREX isokinetic testing system. All participants took isokinetic centrifugal exercise maximally at the speeds of 30, 60, 90, 120, 180 (°)/s, respectively, with a 5 minutes interval. Main outcome measures:①Lumbar range of motion; ②Peak torque, flexor/extensor, the angle at peak torque at isokinetic centripetal exercise; ③Average power and total work at isokinetic centripetal exercise.RESULTS AND CONCLUSION: ①During isokinetic centripetal exercise, the peak torque of extensor were decreased as the geniovelocity increased (P ＜ 0.05), however, no inerratic changes could be found in flexor peak torque. Though the flexor/extensor was increased with geniovelocity increased, the difference had no significance (P ＞ 0.05). ②Dudng slow isokinetic centripetal exercise underwent different geniovelocity, the angle at peak torque of flexor and extensor distributed discretely, -48.56° at 30 (°)/s; -46.18° at 90 (°)/s; when underwent fast isokinetic exercise, the angles at peak torque of flexor and extensor were very close, which were -48.71° and -51.61° at 120 (°)/s, and -54.86° and -53.11° at 180 (°)/s. ③During isokinetic centripetal exercise, when underwent different geniovelocity, total work of flexor and extensor was reduced with geniovelocity expedited, extensor total work was more than that of flexor (P < 0.05); the average power of flexor and extensor was increased linearly with geniovelocity expedited, and the average power of flexor was less than that of extensor all along (P ＜ 0.01). During isokinetic centripetal exercise, trunk muscle strength descended with the geniovelocity expedited, and the stability of trunk is preferable in slow exercise. During fast isokinetic centripetal exercise, angles at flexor and extensor peak torque are more discrete, which easily result in muscle damages and spine unstable when suffered a suddenly outside attack. Total work of flexor and extensor are descended with the geniovelocity expediting during isokinetic exercise, but the intramuscular eruption increased.

This year an outbreak of influenza in Mexico comes from a new epidemic of influenza viruses:A/H1N1 influenza virus.This virus is a kind of virus mixture,including human,avian and swine influenza virus gene fragments.The pathogenic mechanism of avian,swine and human influenza virus in its natural host were compared.The main purpose is to assess the risk of which pigs and poultry has the possibility to become one of zoonotic disease and to assess the possible role in process of avian flu transmission from pigs to people.As zoonotic disease,avian influenza and swine influenza virus have the key role in the process of human infection.But the influenza virus spread of crossing species barrier is not sufficient to cause a large outbreak of human influenza.Animal influenza viruses must have a significant genetic variation before they could live for a long term in the crowd.

Branding has become a core competitiveness for hospitals.They are faced with the question of how to build and maintain their brand,how to apply PDCA cycle in the management of hospital branding strategy,how to keep up the branding with constant analysis,evaluation and adjustment,for the purpose of sustained development.

Wtth the development of imaging technique,particularly the use of magnetic resonance diffusion weighted imaging,it can easily detect silent stroke lesiom.Both the prevalence and incidence of asyrrotomatic stroke were higher than those of symptomatic stroke.Age,hypertemion and atrial fibrillation are its accepted risk factors.Although silent stroke lacks clinically overt stroke-like symptoms by definition,it often has mild physical and cognitive impairment with careful examination.Furthermore,asymptomatic stroke is also correlated with the occurrence of subsequent symptomatic stroke.decreased cognitive function and dementia.Therefore,clinicians should pay more attention to it,positively control its risk factors and improve its prognosis.

Acupuncture Therapy ; Adolescent ; Humans ; Male ; Superior Mesenteric Artery Syndrome ; therapy

Objective To investigate whether emergency rooms in major general public hospitals are reasonably designed and convenient for patients. Methods 78 major public hospitals were selected from all over China, except Hong Kong, Macau and Taiwan, for emergency room convenience analysis. The standards in use were the "Standards of Hospitals" of Joint commission International Accreditation. Results The investigation found in such hospitals the following: poor road conditions outside the clinic and insufficient guides in the clinic; long-than-expected distance (normally over 50 meters) from ER to imaging departments (such as X-ray and CT scan service); ERs in provincial capital cities are significantly more convenient than those in non-capital cities; distance from ERs to CT service is significantly shorter in hospitals in eastern China than those middle and western China. Conclusions Parameters on ER's service quality from "Standards of Hospitals" could serve as a guideline to emergency medicine in China. ERs in China need to improve with conspicuous ER signs, unblocked passageways, and convenient access to inspection departments.

Adult ; Antiretroviral Therapy, Highly Active ; Female ; HIV Infections ; drug therapy ; Humans ; Lamivudine ; administration & dosage ; Male ; Middle Aged ; Treatment Outcome ; Zidovudine ; administration & dosage

Fetal Heart ; Heart Failure ; Heart Rate, Fetal ; Humans

ObjectiveTo investigate the association between endothelial NO synthase (eNOS) gene G10T polymorphism and the susceptibility of sporadic congenital heart disease (CHD).MethodsThe genotype oneNOS G10T locus was detected and compared in 1323 children with sporadic CHD and 1323 non-CHD children.ResultsCompared with the CC genotype, the AA genotype signiifcantly increased the risk of CHD (adjustedOR=1.42, 95%CI=1.01-2.04). Compared with the CC/AC geno-type, the AA genotype signiifcantly increased the risk of CHD (adjustedOR=1.39, 95%CI=1.08-1.92). Based on stratiifed analy-sis, the AA genotype was associated with the susceptibility of perimembranous ventricular septal defects (adjustedOR=1.56, 95%CI=1.17-2.47).ConclusionsIn Chinese population, theeNOS G10T polymorphism may increase the susceptibility of sporadic CHD.