1.Progress and hot topics in clinical management of desmoid tumor
China Oncology 2010;20(3):227-231
Desmoid tumor also known as aggressive fibromatosis,are rare fibroblastic tumors which are derived from deep fascia planes or muscuofascia structures.Resectable extra-abdominal and abdominal desmoid tumor should always be treated with the aim of achieving a negative margin through wide radical resection with margins above 2 cm.Ifthis is not feasible,function-sparing surgical resection is suggested.Adjuvant radiation should be considered for patients with positive margins,recirrent tumors or unresectable diseases.Intra-abdominal desmoid tumor is common in patients with familial adenomatous polyposis.It has a high recurring rate after surgical resection and therefore a high dosage of tamoxifen and sulindac are recommended as first-line treatment.Due to the variable nature of the outcome and vague reaction to drug therapy,individualized treatments,including the wait and see policy,has been widely investigated and thought to be a promising strategy for the future.
2.Determination of Sulfuric Acid Mist in Air by Ion Chromatography
Journal of Environment and Health 2007;0(12):-
Objective To develop a quick, simple and sensitive method for determination of sulfuric acid mist in the air by ion chromatography. Methods The samples were collected by Nillipore filter, Na2CO3-NaHCO3 solution was used and the samples were analyzed by using ion-chromatography as well as external standard curve. Results The linear range of the method was 0.5-10.0 ?g/ml and the correlation coefficient was 0.999 8. The RSD for the test accuracy and variation of repeat tests within one day or between the different days was
3.Vascular endothelial growth factor and its effect on bone formation
Kai CAO ; Hong AN ; Dianming JIANG
Chinese Journal of Tissue Engineering Research 2005;9(2):248-251
OBJECTIVE: To review the outcomes of experiments about vascular endothelial growth factor(VEGF) and the effect of it on bone formation, and to make sure whether VEGF can promote bone formation or not.DATA SOURCES: Electronic data searches were performed to obtain data from the databases of http://www.ncbi. nlm. nih. gov/pubmed and http://www. zglckf.com. DATA SELECZION: Nearly 30 articles about VEGF and the role of VEGF affecting bone formation were selected, regardless of the randomized design,blind method involved in or not.DATA EXTRACTION: These researches proved the structures, biologic properties and expression of VEGF and vascular endothelial growth factor receptor(VEGFR), and showed that VEGF plays an important role in endochondral ossification by promoting angiogenesis, bone turnover and preventing apoptosis of chondrocyte. In intramembranous ossification, absence of cartilage, osteoblasts are likely producing, and responding to, VEGF. VEGF also acts to recruit and activate osteoclasts as well as stimulate osteoblast chemotaxis, differentiation and matrix mineralization. It is debatable whether local application of exogenous VEGF can promote bone repair or not. However, in certain situation such as ischemia, the increase of VEGF locally may promote bone repair.DATA SYNTHESIS: Compared with the control group, VEGF can promote osteogenesis, bone formation and remodeling through the effect of VEGF on endochondral ossification and intramembranous ossification.CONCLUSION: One possible advantage of local VEGF therapy may be its ability to couple angiogenesis with bone formation and remodeling. If we can ultimately apply VEGF to treat osteonecrosis, bone defect and nonunion, we will find a new therapy for these diseases.
4.Update on classification of precancerous lesions of larynx.
Hong-kai ZHANG ; Hong-gang LIU
Chinese Journal of Pathology 2010;39(8):570-573
Alcohol Drinking
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Carcinoma in Situ
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pathology
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Epithelium
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pathology
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Gastroesophageal Reflux
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complications
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Humans
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Hyperplasia
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Laryngeal Neoplasms
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classification
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etiology
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pathology
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therapy
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Larynx
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pathology
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Papillomavirus Infections
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Precancerous Conditions
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classification
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etiology
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pathology
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therapy
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Prognosis
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Smoking
5.Laparoscopy in treatment of renal cysts
Hong-Yi DING ; Kai-Hen LI ; Zheng-Kai WU ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(09):-
Objective To evaluate the effect of laparoscopy in treatment of renal cysts.Methods Twenty- eight and thirty-five patients with renal cysts were performed with transperituneal and retroperitonel laparoscopy,re- spectively.Results A total of 62 patients were treated successfully,the average operation time was 60 minutes,no complications presented,and there was no recurrence in follow-up.Conclusion Laparoseopy survey had the advan- tages of less trauma and fewer complications and rapid recovery in treatment of renal cysts,which was suggested for clinical applications.
6.Developmental and Experimental Study of Bionic Bone MHA-bBMP
Kai-fang ZHANG ; Hong-wei YAN ; Kai LIU ; Tao LIU
Chinese Journal of Rehabilitation Theory and Practice 2006;12(8):689-691
ObjectiveTo investigate the effort of MHA-bBMP implantation combined with limited contacted titanium net duct fixation on femoral shaft bone defect of rabbit.Methods48 rabbits were divided into the experimental group (treated with bionic bone MHA-bBMP plus titanium net duck) and control group (treated with iliac autograft plus titanium net duct) with 24 animals in each group. The rabbit femoral shaft bone defect model was established by cutting 10 mm bone fragment off. After operation, bionic bone MHA-bBMP/iliac autograft was implanted into bone defect area and fixed with limited contacted titanium net duck. The general condition, serum alkaline phosphatase, X-ray, histopathologic examination and electron microscope were performed.ResultsThe fixation stability of titanium net duck in two groups was good. The bone defect of two groups was repaired. The results of phosphatase, X-ray, histopathologic examination and electron microscope of two groups were not significantly different.ConclusionBionic bone MHA-bBMP is a high bioactivity substitute, and can obtain therapeutic effect equal to iliac autograft when repairing rabbit's femoral shaft defect.
7.The ambitious but achievable goal: to end preventable childhood deaths due to pneumonia by 2025.
Chinese Journal of Contemporary Pediatrics 2014;16(10):967-969
Globally, pneumonia is the leading cause of childhood mortality. Pneumonia is the second killer of children less than 5 years of age in China. The World Heath Organization and United Nations Children′s Fund launched the integrated Global Action Plan for the Prevention and Control of Pneumonia and Diarrhea (GAPPD) in 2013. The ambitious goal is to end preventable childhood deaths due to pneumonia by 2025. Countries or regions should achieve the following goals: (1) reduce mortality from pneumonia in children less than 5 years of age to fewer than 3 per 1 000 live births; (2) reduce the incidence of severe pneumonia by 75% in children less than 5 years of age compared to 2010 levels. If the implementation of key interventions is accelerated, the mortality rate of childhood pneumonia will drop substantially every year, which makes the goal achievable.
Child Mortality
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trends
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Child, Preschool
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China
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epidemiology
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Humans
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Infant
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Infant, Newborn
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Pneumonia
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mortality
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Time Factors
10.Cytophagic histiocytic panniculitis.
Jie SHI ; Hong-rui LIU ; Kai FANG
Chinese Journal of Pathology 2005;34(1):59-60
Adult
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Antineoplastic Combined Chemotherapy Protocols
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administration & dosage
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therapeutic use
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Cyclophosphamide
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administration & dosage
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Diagnosis, Differential
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Female
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Humans
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Panniculitis
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drug therapy
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pathology
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Panniculitis, Nodular Nonsuppurative
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pathology
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Prednisone
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administration & dosage
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Vincristine
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administration & dosage