Objective To investigate the clinical effect of atorvastatin combined with lopidogrel in patients with transient ischemic attack.Methods Totally 92 cases of patients with transient ischemic attack in Xingyuan Hospital of Yulin City from January 2013 to August 2015 were divided into observation group and control group,46 cases in each group.Patients in observation group were treated with atorvastatin combined with lopidogrel,and patients in control group were treated with lopidogrel.The differences in short term effect,long-term effect,and adverse reaction between two groups were compared.Results The total effective rate of observation group was significantly higher than that of control group (P ＜ 0.05);After treatment,the levels of hs-CPR,Lp-PLA2TC,TG,and LDL,the recurrence rate of transient ischemic attack and the incidence of cerebral infarction of the observation group were significantly lower than that of the control group and before treatment (P ＜ 0.05),but the differences in PLT,PT,and APTT between two groups before and after treatment were not significant.Conclusion The clinical effect of atorvastatin combined with lopidogrel in patients with transient ischemic attack were remarkable,and the incidence of adverse events do not increase.

Based on the structure of TCM tongue image recognition system,digital image processing technology in tongue objectiveness research is analyzed,especially on the methods and principles of color correction,image segmentation,pattern recognition,etc.The future development is also discussed.

Eight-year medical education has been run in some of the unversities in China,which has made some effective trials in personnel training mode according to the training purposes sent by Ministry of Education,but there still exists weaknesses in curriculum provision and reasearch training.This article briefly analyzed the major construction of the eight-year medical education and displayed several views.

Recent advances in medical ultrasonic instrumentation are introduced in this review, including the progresses in transducer, diagnostic and therapeutic applications. Future development is also discussed.
Equipment Design ; Image Enhancement ; instrumentation ; methods ; Imaging, Three-Dimensional ; instrumentation ; methods ; Transducers ; Ultrasonic Therapy ; instrumentation ; trends ; Ultrasonics ; Ultrasonography ; instrumentation ; trends

[Objective]To evaluate the value of clinical examination and magnetic resonance imaging in diagnosing chronic anterior cruciate ligament injury.[Method]Sixty-five patients with the diagnosis of chronic anterior cruciate ligament injury were retrospectively analyzed about the course of diagnosis and treatment.To gain the primary diagnosis through clinical examination,8 patients were performed magnetic resonance imaging.Finally all the patients were carried out arthroscopic surgery to make a final diagnosis.[Result]Arthroscopy found 53 cases with complete anterior cruciate ligament tears,12 cases with partial anterior cruciate ligament tears.In the complete anterior cruciate ligament tears cases,79.2% patients had positive anterior drawer test,96.2% had positive Lachman test and 92.5 % had positive pivot shift test.In the partial anterior cruciate ligament tears cases,16.7% patients had positive anterior drawer test,50.0% had positive Lachman test and 33.3 % had positive pivot shift test.The accuracy of MRI in diagnosing anterior cruciate ligament tears was 100%.[Conclusion]Clinical examination and magnetic resonance imaging can diagnose chronic anterior cruciate ligament effectively.

Objective To study the effect of CO2 pneumoperitoneum on migration of GFP-labeled living cells into the liver through blood route in rat model.Methods SD rats was inoculated intraportally with high-dose(5?106) GFP-labeled liver cells from C57BL/6 mice after cutting belly open.Pneumoperitoneum was established immediately after closing the abdominal wall.The rats were randomly divided into four groups(n=10 in each) to receive CO2 pneumoperitoneum at 5,10,or 15 mmHg,or no treatment other than cells inoculation(control).The pneumoperitoneum was maintained for 30 min.Afterwards,the rats were euthanized by cervical dislocation,and the liver of the rats was removed for fast frozen section biopsy.The expression of GFP-labeled living cells in rat livers was compared between the groups.Results No significant difference was detected in the positive expression of GFP-labeled cells between the groups(8 rats in the control group,9 in the 5 mm Hg group,9 in the 10 mm Hg group,and 10 in the 15 mm Hg group,?2=2.222,P=0.528).The mean number of GFP-positive cells in the four groups was 6.63?2.45(control),7.67?2.83(5 mm Hg),13.89?4.37(10 mm Hg),and 15.50?6.29(15 mm Hg).There was significant differences between the four groups(F=10.78,P=0.000).In addition,the numbers of GFP-positive cells in the high pressure groups(15 mm Hg and 10 mm Hg) were significantly higher than that in the low pressure group(5 mm Hg) and the control(P

Through the improvement on determination of rhTNF-? bioassay, we established the formal procedure . Methods; We choose L929 cell for rhTNF-? bioassay determination. To identify the influence of rhTNF-? on the growth of HL-60 cells, various concentration and effecting time were studied. Results: The results showed that the inhibition of rhTNF-? on HL-60 cells based on dose and time. Northern Dot Blot and DNA electrophoresis showed c-myc gene was surpressed, and DNA was damaged by rhTNF-?. Conclusion: Autometic calculation is responsible for bioassay of rhTNF-?. rhTNF-? could inhibit the proliferation of HL-60 cells and its mechanism is different from doxirubicin.

Objective: To establish National Standard of rhTNF-? complying with the requirements of research and quality control. Methods: National Standard of rhTNF-? were assayed against international standard (NIBSC) of rhTNF-? by cytotoxicity bioassay (L929 ) in vitro. The collaborative study has been carried out among four laboratories. Results: Based on the statistical analysis the results show that mean pf 95 % confidence interval is 3 289 ~ 4 266 IU per ampoule; the 95 % reference range is 1 735 ~ 8 087 IU per ampoule. Based on this study, the potency of rhTNF-? standard is defined as 3500 IU per ampoule. Stability tests indicate that the bioactivity has not been changed significandy under the storage of four different temperautres for 27 monthes. Conclusion: The preparation of rhTNF-? met the requirement of quality and could be used as a National Standard.

Objective To study the optimum inclusion process for volatile oil from Tongketing capsules. Methods The study was carried out with orthogonal test at different levels. The utilization ratio of volatile oil was used as the index to optimize the inclusion process. Results The optimum preparation conditions for inclusion were: oil: ?-cyclodextrin: water was 1: 4: 40 (V: V: V). The inclusion time was 10rain and inclusion complexes was dried at 70℃. Conclusion This optimized process is simple, efficient and can be used for the production of Tongketing Capsule on a large scale.