1.Pregnancy-related osteoporosis and spinal fractures.
Ka Yeong YUN ; Si Eun HAN ; Seung Chul KIM ; Jong Kil JOO ; Kyu Sup LEE
Obstetrics & Gynecology Science 2017;60(1):133-137
Pregnancy-related osteoporosis is a very rare condition characterized by the occurrence of fracture during pregnancy or the puerperium. Despite its relative rarity, it can be a dangerous condition that causes severe back pain, height loss and disability. Normal physiologic changes during pregnancy, genetic or racial difference, obstetrical history and obstetrical disease, such as preterm labor or pregnancy-induced hypertension, are presumed risk factors of pregnancy-related osteooporosis. However, exact etiology and pathogenesis are uncertain. The management and natural history are still poorly defined. Traditional medications for osteoporosis are calcium/vitamin D and bisphosphonate. Concerns with bisphosphonate include accumulation in bone and fetal exposure in subsequent pregnancies. The newly developed medication, teriparatide, has shown good results. We report six cases of pregnancy-related osteoporosis and spinal fracture with literature review.
Back Pain
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Female
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Hypertension, Pregnancy-Induced
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Natural History
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Obstetric Labor, Premature
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Osteoporosis*
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Postpartum Period
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Pregnancy
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Risk Factors
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Spinal Fractures*
;
Teriparatide
2.The Relationship between Renal Function and Bone Marrow Density in Healthy Korean Women.
Byung Kyu PARK ; Ka Yeong YUN ; Seung Chul KIM ; Jong Kil JOO ; Kyu Sup LEE ; Ook Hwan CHOI
Journal of Menopausal Medicine 2017;23(2):96-101
OBJECTIVES: The relationship between renal function and bone mineral density (BMD) is controversial. We evaluated the relationship between markers of renal function and BMD in healthy Korean women. METHODS: A total of 1,093 women who visited the health promotion center at Pusan National University hospital were included in the cross-sectional study. We divided the study population into two groups by BMD: osteopenia-osteoporosis and normal in the lumbar and femur regions, respectively. We compared the relationship between renal function and BMD using a logistic regression model and used SAS 9.3 (SAS Institute, Inc., Cary, NC, USA) for all statistical analysis. RESULTS: Blood urea nitrogen (BUN), creatinine, and cystatin C (Cys-C) were correlated with BMD in both the normal and osteopenia-osteoporosis groups, and in logistic regression analysis, BUN and Cys-C were correlated with lumbar and femur BMD. However, after we adjusted for age, menopause, and body mass index, only creatinine showed a negative correlation with lumbar BMD, and estimated glomerular filtration rate (eGFR) was related positively with femur BMD. CONCLUSIONS: Serum creatinine could be a marker for lumbar BMD and eGFR for femur BMD in Korean women without overt nephropathy.
Blood Urea Nitrogen
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Body Mass Index
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Bone Density
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Bone Marrow*
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Busan
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Creatinine
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Cross-Sectional Studies
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Cystatin C
;
Female
;
Femur
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Glomerular Filtration Rate
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Health Promotion
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Humans
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Logistic Models
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Menopause
;
Osteoporosis
3.Management of Proteus Syndrome with Craniofacial Hemihyperostosis: Case Report
Yeong Eun YUN ; Ka Young SEOL ; Min Seok OH ; Jung Goo CHOI ; Sang Jung KIM ; Dong Keun LEE ; Ji Yeon KANG
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 2011;33(6):540-548
Congenital Abnormalities
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Extremities
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Gigantism
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Hemangioma
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Humans
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Hyperostosis
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Hyperplasia
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Lipoma
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Lymphangioma
;
Macrocephaly
;
Male
;
Mouth
;
Nevus
;
Osteotomy
;
Proteus
;
Proteus Syndrome