Purpose: : This study is a descriptive research study to identify factors that influence the career preparation behavior of nursing students. Methods: : The subjects were 153 students attending nursing school. The data were analyzed using the SPSS Statistics 25.0 program with descriptive statistics, t-test, ANOVA, Scheffé test and Pearson’s correlation coefficients and stepwise multiple regression analysis. Results: : The degree of career preparation behavior of the subjects differed depending on their interpersonal relationships(F=3.093, p=.029). The subject’s career preparation behavior had a positive correlation with nursing professionalism and self-efficacy. As a result of stepwise regression analysis, factors related to the subject’s career preparation behavior were found to be in the order of self-efficacy and nursing professionalism. These variables were found to explain 14.7% of career preparation behavior (F=12.903, p<.001). Nursing professionalism (t=3.283, p=.001), professor trust (t=2.148, p=.033), and self-efficacy (t=2.745, p=.007) of subjects with high career preparation behavior scores were higher than those of subjects with low career preparation behavior scores. Conclusion : It was found that nursing students’ nursing professional intuition and self-efficacy influenced career preparation behavior. In addition, nursing students with a high level of career preparation behavior were found to have higher nursing professional intuition, trust in professors, and self-efficacy than nursing students with a low level of career preparation behavior. Based on the results of this study, efforts are needed to improve nursing professional intuition and self-efficacy in order to promote career preparation behavior among nursing students.

Primary aldosteronism is a group of disorders in which the autonomous secretion of aldosterone is associated with hypertension and hypokalemia. It is crucial to determine the laterality of aldosterone hypersecretion because treatment options differ accordingly. Adrenal venous sampling (AVS) is considered the most reliable method for assessing the laterality of primary aldosteronism. This procedure is often technically challenging because of the small size and varied locations of the adrenal veins. A better understanding of anatomical variations and careful review of imaging studies would improve sampling success. This report presents three cases of anatomical variations encountered during AVS.

Purpose: : This study is a descriptive research study to identify factors that influence the career preparation behavior of nursing students. Methods: : The subjects were 153 students attending nursing school. The data were analyzed using the SPSS Statistics 25.0 program with descriptive statistics, t-test, ANOVA, Scheffé test and Pearson’s correlation coefficients and stepwise multiple regression analysis. Results: : The degree of career preparation behavior of the subjects differed depending on their interpersonal relationships(F=3.093, p=.029). The subject’s career preparation behavior had a positive correlation with nursing professionalism and self-efficacy. As a result of stepwise regression analysis, factors related to the subject’s career preparation behavior were found to be in the order of self-efficacy and nursing professionalism. These variables were found to explain 14.7% of career preparation behavior (F=12.903, p<.001). Nursing professionalism (t=3.283, p=.001), professor trust (t=2.148, p=.033), and self-efficacy (t=2.745, p=.007) of subjects with high career preparation behavior scores were higher than those of subjects with low career preparation behavior scores. Conclusion : It was found that nursing students’ nursing professional intuition and self-efficacy influenced career preparation behavior. In addition, nursing students with a high level of career preparation behavior were found to have higher nursing professional intuition, trust in professors, and self-efficacy than nursing students with a low level of career preparation behavior. Based on the results of this study, efforts are needed to improve nursing professional intuition and self-efficacy in order to promote career preparation behavior among nursing students.

Primary aldosteronism is a group of disorders in which the autonomous secretion of aldosterone is associated with hypertension and hypokalemia. It is crucial to determine the laterality of aldosterone hypersecretion because treatment options differ accordingly. Adrenal venous sampling (AVS) is considered the most reliable method for assessing the laterality of primary aldosteronism. This procedure is often technically challenging because of the small size and varied locations of the adrenal veins. A better understanding of anatomical variations and careful review of imaging studies would improve sampling success. This report presents three cases of anatomical variations encountered during AVS.

Purpose: : This study is a descriptive research study to identify factors that influence the career preparation behavior of nursing students. Methods: : The subjects were 153 students attending nursing school. The data were analyzed using the SPSS Statistics 25.0 program with descriptive statistics, t-test, ANOVA, Scheffé test and Pearson’s correlation coefficients and stepwise multiple regression analysis. Results: : The degree of career preparation behavior of the subjects differed depending on their interpersonal relationships(F=3.093, p=.029). The subject’s career preparation behavior had a positive correlation with nursing professionalism and self-efficacy. As a result of stepwise regression analysis, factors related to the subject’s career preparation behavior were found to be in the order of self-efficacy and nursing professionalism. These variables were found to explain 14.7% of career preparation behavior (F=12.903, p<.001). Nursing professionalism (t=3.283, p=.001), professor trust (t=2.148, p=.033), and self-efficacy (t=2.745, p=.007) of subjects with high career preparation behavior scores were higher than those of subjects with low career preparation behavior scores. Conclusion : It was found that nursing students’ nursing professional intuition and self-efficacy influenced career preparation behavior. In addition, nursing students with a high level of career preparation behavior were found to have higher nursing professional intuition, trust in professors, and self-efficacy than nursing students with a low level of career preparation behavior. Based on the results of this study, efforts are needed to improve nursing professional intuition and self-efficacy in order to promote career preparation behavior among nursing students.

Primary aldosteronism is a group of disorders in which the autonomous secretion of aldosterone is associated with hypertension and hypokalemia. It is crucial to determine the laterality of aldosterone hypersecretion because treatment options differ accordingly. Adrenal venous sampling (AVS) is considered the most reliable method for assessing the laterality of primary aldosteronism. This procedure is often technically challenging because of the small size and varied locations of the adrenal veins. A better understanding of anatomical variations and careful review of imaging studies would improve sampling success. This report presents three cases of anatomical variations encountered during AVS.

Purpose: NUT carcinoma (NC) is a solid tumor caused by the rearrangement of NUTM1 that usually develops in midline structures, such as the thorax. No standard treatment has been established despite high lethality. Thus, we investigated whether targeting the junction region of NUTM1 fusion breakpoints could serve as a potential treatment option for NC. Materials and Methods: We designed and evaluated a series of small interfering RNAs (siRNAs) targeting the junction region of BRD4-NUTM1 fusion (B4N), the most common form of NUTM1 fusion. Droplet digital polymerase chain reaction using the blood of patients was also tested to evaluate the treatment responses by the junction sequence of the B4N fusion transcripts. Results: As expected, the majority of NC fusion types were B4N (12 of 18, 67%). B4N fusion-specific siRNA treatment on NC cells showed specific inhibitory effects on the B4N fusion transcript and fusion protein without affecting the endogenous expression of the parent genes, resulting in decreased relative cell growth and attenuation of tumor size. In addition, the fusion transcript levels in platelet-rich-plasma samples of the NC patients with systemic metastasis showed a negative correlation with therapeutic effect, suggesting its potential as a measure of treatment responsiveness. Conclusion This study suggests that tumor-specific sequences could be used to treat patients with fusion genes as part of precision medicine for a rare but deadly disease.

Background: Axillary bromhidrosis is a disease characterized by malodor caused by the interaction between apocrine gland secretions and bacteria. Current treatment modalities include topical treatment, liposuction curettage, microwave therapy, and surgical intervention. Objective: This retrospective study aimed to evaluate the clinical outcomes and quality of life over a 3-year follow-up period of the 1,444-nm Nd:YAG laser and surgical treatment for bromhidrosis. Methods: Forty-five patients participated in the study, with 20 patients receiving laser treatment and 25 patients undergoing surgery using the modified Inaba method. The degree of remaining axillary malodor, pain, reduced mobility, and overall patient satisfaction were assessed retrospectively through medical records and direct or indirect patient interviews at 7 days, 1 month, 2 months, 6 months, 1 year, and 3 years after each treatment. The modified Dermatology Life Quality Index (DLQI) was used to evaluate the quality of life. Results: Over the course of all the assessed time periods, the remaining odor and overall satisfaction scores did not differ significantly between the two groups. However, the laser-treated group reported significantly lower pain scores, reduced mobility, and total DLQI score. There were no significant differences in adverse events between the two groups. Conclusion In our study, laser treatment for bromhidrosis showed comparable efficacy to surgery. Moreover, fewer adverse events occurred in the laser group. In addition, patient quality of life was better after laser treatment. In conclusion, subdermal coagulation treatment with the 1,444-nm Nd:YAG laser may be a less invasive and effective therapy for bromhidrosis.

Objectives: The number of reported cases of Legionnaires’ disease (LD) in the Republic of Korea surged nationally in 2016; however, in 2022, this number was higher in Jeju Province than the previous national peak. A descriptive epidemiological study was conducted to analyze trends in the incidence of reported LD cases in Jeju Island from 2015 to 2022. Methods: The data for this study were obtained from case reports submitted to the Korea Disease Control and Prevention Agency through its Disease and Health Integrated Management System. The selection criteria were cases or suspected cases of LD reported among Jejuresidents between 2015 and 2022. The 95% confidence interval of the crude incidence rate wascalculated using the Poisson distribution. Results: Since 2020, the incidence rate of LD in Jeju has risen sharply, showing a statistically significant difference from the national incidence rate. A particular medical institution in Jeju reported a significant number of LD cases. Screening with the urine antigen test (UAT) also increased significantly. Conclusion Our findings indicate that the rapid increase in cases of LD in Jeju Province since 2020 was due to the characteristics of medical-care use among Jeju residents, which were focused on a specific medical institution. According to their clinical practice guidelines, this medical institution conducted UATs to screen patients suspected of pneumonia.