1.Clinical Outcomes and Satisfaction with Laser Treatment and Surgery of Axillary Bromhidrosis Patients: A Retrospective Analysis
Jong Heon PARK ; Juyoung JO ; Il-Hwan KIM
Korean Journal of Dermatology 2023;61(4):209-216
Background:
Axillary bromhidrosis is a disease characterized by malodor caused by the interaction between apocrine gland secretions and bacteria. Current treatment modalities include topical treatment, liposuction curettage, microwave therapy, and surgical intervention.
Objective:
This retrospective study aimed to evaluate the clinical outcomes and quality of life over a 3-year follow-up period of the 1,444-nm Nd:YAG laser and surgical treatment for bromhidrosis.
Methods:
Forty-five patients participated in the study, with 20 patients receiving laser treatment and 25 patients undergoing surgery using the modified Inaba method. The degree of remaining axillary malodor, pain, reduced mobility, and overall patient satisfaction were assessed retrospectively through medical records and direct or indirect patient interviews at 7 days, 1 month, 2 months, 6 months, 1 year, and 3 years after each treatment. The modified Dermatology Life Quality Index (DLQI) was used to evaluate the quality of life.
Results:
Over the course of all the assessed time periods, the remaining odor and overall satisfaction scores did not differ significantly between the two groups. However, the laser-treated group reported significantly lower pain scores, reduced mobility, and total DLQI score. There were no significant differences in adverse events between the two groups.
Conclusion
In our study, laser treatment for bromhidrosis showed comparable efficacy to surgery. Moreover, fewer adverse events occurred in the laser group. In addition, patient quality of life was better after laser treatment. In conclusion, subdermal coagulation treatment with the 1,444-nm Nd:YAG laser may be a less invasive and effective therapy for bromhidrosis.
2.Transvenous Coil Embolization for Dural Arteriovenous Fistulas of the Ophthalmic Sheath: Report of Two Cases and Review of the Literature.
Juyoung HWANG ; Kyung Il JO ; Je Young YEON ; Seung Chyul HONG ; Jong Soo KIM
Journal of Cerebrovascular and Endovascular Neurosurgery 2016;18(2):135-140
We present two patients with a dural arteriovenous fistula (dAVF) of the ophthalmic sheath who developed progressive exophthalmos, conjunctival chemosis, and visual loss. These symptoms mimic those of cavernous sinus dAVFs. Dural AVFs of the ophthalmic sheath are extremely rare and their clinical management is controversial. We successfully treated these two patients by transvenous coil embolization. Transvenous embolization appears to be a safe and effective method to treat dAVFs of the ophthalmic sheath.
Cavernous Sinus
;
Central Nervous System Vascular Malformations*
;
Embolization, Therapeutic*
;
Exophthalmos
;
Humans
;
Methods
3.Health-related Quality of Life Instrument With 8 Items for Use in Patients With Type 2 Diabetes Mellitus: A Validation Study in Korea
Juyoung KIM ; Hyeon-Jeong LEE ; Min-Woo JO
Journal of Preventive Medicine and Public Health 2022;55(3):234-242
Objectives:
This study assessed the validity and reliability of the Health-related Quality of Life Instrument with 8 Items (HINT-8) in patients with diabetes. HINT-8 is a newly-developed, generic health-related quality of life (HRQoL) instrument.
Methods:
Three HRQoL instruments—HINT-8, EuroQoL 5-Dimension 5-Level (EQ-5D-5L), and Short Form Health Survey version 2.0 (SF-36v2)—were provided to 300 patients with diabetes visiting a tertiary hospital for follow-up visits in Korea. The HRQoL scores obtained using the HINT-8 were evaluated for subgroups with known differences based on demographics and diabetes-related characteristics (known-group validity). The mean scores of the instruments were compared between groups segmented by their responses to the HINT-8 (discriminatory ability). Correlation coefficients of the HINT-8 with other instruments were calculated (convergent and divergent validity). The Cohen kappa and intra-class correlation coefficient (ICC) were also evaluated (test-retest reliability).
Results:
The average HINT-8 indexes were lower among women, older, and less-educated subjects. Subjects who did not list any problems on the HINT-8 had significantly higher HRQoL scores than those who did. The correlation coefficients of the HINT-8 with the EQ-5D-5L index and EuroQoL visual analogue scale were 0.715 (p<0.001) and 0.517 (p<0.001), respectively. The correlation coefficients between the HINT-8 index and the scores of 8 domains of the SF-36v2 ranged from 0.478 (p<0.001) to 0.669 (p<0.001). The Cohen kappa values for the HINT-8 ranged from 0.268 to 0.601, and the ICC of the HINT-8 index was 0.800 (95% confidence interval [CI], 0.720 to 0.860).
Conclusions
This study showed that the HINT-8 is a valid and reliable HRQoL instrument for patients with diabetes.
4.Knowledge and Acceptability about Adult Pertussis Immunization in Korean Women of Childbearing Age.
Hyun Sun KO ; Yun Seong JO ; Yeun Hee KIM ; Yong Gyu PARK ; Jeong Ha WIE ; Juyoung CHEON ; Hee Bong MOON ; Young LEE ; Jong Chul SHIN
Yonsei Medical Journal 2015;56(4):1071-1078
PURPOSE: The adult tetanus, reduced diphtheria, and acellular pertussis (Tdap) vaccine has been introduced in order to provide individual protection and reduce the risk of transmitting pertussis to infants. We assessed the knowledge and acceptability of the Tdap vaccine around pregnancy. MATERIALS AND METHODS: This study was a cross-sectional survey of women of childbearing age (20-45 years) who visited obstetrics and gynecologic units of primary, secondary, or tertiary hospitals. They were asked to fill in a questionnaire assessing their knowledge, attitudes, and acceptability of Tdap. RESULTS: The questionnaire was completed by 308 women; 293 (95.1%) had not received information from doctors about Tdap, and 250 (81.2%) did not know about the need for vaccination. A significantly important factor related to subjects' intention to be vaccinated, identified by stepwise multiple logistic regression, was the knowledge (OR 13.5, CI 3.92-46.33) that adult Tdap is effective in preventing pertussis for infants aged 0-6 months. Additionally, 276 (89.6%) considered the recommendation of obstetric doctors as the most influencing factor about Tdap vaccination. CONCLUSION: In Korea, most women of childbearing age seem to be neither recommended nor adequately informed about the vaccination, although our population was not a nationwide representative sample. Information given by healthcare workers may be critical for improving awareness and preventing pertussis.
Adult
;
Cross-Sectional Studies
;
Diphtheria
;
Diphtheria-Tetanus-acellular Pertussis Vaccines/*administration & dosage
;
Female
;
Health Knowledge, Attitudes, Practice/*ethnology
;
Humans
;
Immunization/*statistics & numerical data
;
Infant
;
Logistic Models
;
Multivariate Analysis
;
Patient Acceptance of Health Care/*ethnology/statistics & numerical data
;
Pregnancy
;
Republic of Korea/epidemiology
;
Risk
;
Surveys and Questionnaires
;
Tetanus
;
Vaccination
;
Whooping Cough/diagnosis/ethnology
5.A case of HELLP syndrome accompanied by retinal detachment.
Soo Yeon JUNG ; Juyoung SHIN ; Eun Jung JEON ; Jung Hwan OH ; Jeong Jo JEONG ; Nam Ik HAN ; Sang WooK CHOI
Korean Journal of Medicine 2009;76(Suppl 1):S22-S25
Weinstein et al. first described the HELLP (hemolytic anemia, elevated liver enzymes, and low platelets) syndrome in 1982. The incidence of HELLP syndrome is 0.2~0.6% in normal pregnant women and 4~12% in women with preeclampsia. This syndrome is accompanied by serious medical complications, including hepatic and renal failure, coagulopathy, hypertension, and pulmonary edema. Retinal detachment is an unusual, but well documented, complication of hypertensive disorder in pregnancy affecting 0.2~2% of patients with severe preeclampsia and 0.9% of patients with HELLP syndrome. This paper reports on a patient with HELLP syndrome accompanied by retinal detachment who recovered after controlling the blood pressure and receiving systemic steroids.
Anemia
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Blood Pressure
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Female
;
HELLP Syndrome
;
Humans
;
Hypertension
;
Incidence
;
Liver
;
Pre-Eclampsia
;
Pregnancy
;
Pregnant Women
;
Pulmonary Edema
;
Renal Insufficiency
;
Retinal Detachment
;
Retinaldehyde
;
Steroids
6.Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients
Juyoung KIM ; Min-Woo JO ; Hyeon-Jeong LEE ; Sei-Hyun AHN ; Byung Ho SON ; Jong Won LEE ; Sae Byul LEE
Osong Public Health and Research Perspectives 2021;12(4):254-263
Objectives:
This study evaluated the validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in postoperative breast cancer patients in South Korea.
Methods:
The study included 300 breast cancer patients visiting a tertiary hospital. We measured health-related quality of life (HRQoL) using the HINT-8, the 5-level EQ-5D version (EQ-5D-5L), and the Functional Assessment of Cancer Therapy-Breast (FACT-B). Discriminatory ability, known-group validity, and convergent validity were assessed. Reliability was evaluated with the Cohen kappa, weighted kappa, and intraclass correlation coefficient (ICC).
Results:
The EQ-5D-5L indexes (p<0.001) and EQ visual analogue scale (VAS) scores (p<0.001) were significantly higher in subjects with no problems in each item of the HINT-8 than in those with problems. The FACT-B total scores were also higher in subjects without problems on the HINT-8. Older age, lower education level, and comorbidities were associated with a lower HINT-8 index. The HINT-8 index was correlated with the EQ-5D-5L index and the EQ VAS, with correlation coefficients of 0.671 (p<0.001) and 0.577 (p<0.001), respectively. The correlation coefficients between the HINT-8 and the FACT-B ranged from 0.390 to 0.714. The ICC was 0.690 (95% confidence interval, 0.580–0.780).
Conclusion
The HINT-8 showed appropriate validity for capturing HRQoL in postoperative breast cancer patients.
7.Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients
Juyoung KIM ; Min-Woo JO ; Hyeon-Jeong LEE ; Sei-Hyun AHN ; Byung Ho SON ; Jong Won LEE ; Sae Byul LEE
Osong Public Health and Research Perspectives 2021;12(4):254-263
Objectives:
This study evaluated the validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in postoperative breast cancer patients in South Korea.
Methods:
The study included 300 breast cancer patients visiting a tertiary hospital. We measured health-related quality of life (HRQoL) using the HINT-8, the 5-level EQ-5D version (EQ-5D-5L), and the Functional Assessment of Cancer Therapy-Breast (FACT-B). Discriminatory ability, known-group validity, and convergent validity were assessed. Reliability was evaluated with the Cohen kappa, weighted kappa, and intraclass correlation coefficient (ICC).
Results:
The EQ-5D-5L indexes (p<0.001) and EQ visual analogue scale (VAS) scores (p<0.001) were significantly higher in subjects with no problems in each item of the HINT-8 than in those with problems. The FACT-B total scores were also higher in subjects without problems on the HINT-8. Older age, lower education level, and comorbidities were associated with a lower HINT-8 index. The HINT-8 index was correlated with the EQ-5D-5L index and the EQ VAS, with correlation coefficients of 0.671 (p<0.001) and 0.577 (p<0.001), respectively. The correlation coefficients between the HINT-8 and the FACT-B ranged from 0.390 to 0.714. The ICC was 0.690 (95% confidence interval, 0.580–0.780).
Conclusion
The HINT-8 showed appropriate validity for capturing HRQoL in postoperative breast cancer patients.
8.A Case of Retrograde Jejunogastric Intussusception Diagnosed by Gastroscopy.
Hyeug LEE ; Eun Ok KIM ; Juyoung SHIN ; Seung Hyun OH ; Hong Seok SONG ; Eun Jung JEON ; Jung Hwan OH ; Jeong Jo JEONG ; Sang Wook CHOI ; Sung Geun KIM ; Sang Seob YUN ; Seong LEE
Korean Journal of Gastrointestinal Endoscopy 2008;37(2):112-115
Retrograde intussusception of the jejunum into the stomach through the stroma of a gastroenterostomy is a very rare, but potentially fatal complication after gastrectomy. Once symptoms develop, the mortality rate is high if this is not treated within 48 hours, so making an early diagnosis with a high index of suspicion and administering prompt treatment are mandatory. Gastroscopy could be a useful diagnostic tool for patients with a history of gastrectomy and who present with abdominal pain and hematemesis, and with considering the possibility of intussusception. A 65-year-old man with a history of Billroth II gastrectomy that was done 35 years ago due to gastric ulcer perforation was admitted with abdominal pain and hematemesis. A necrotic mucosa that was suspicious of an intussuscepted small bowel tissue was detected on gastroscopy. Subsequent open reduction and small bowel resection was performed with successful results. We report here on a case of postoperative retrograde jejunogastric intussusception that occurred 35 years after Billroth II gastrectomy, and it was first diagnosed by performing gastroscopy.
Abdominal Pain
;
Aged
;
Early Diagnosis
;
Gastrectomy
;
Gastroenterostomy
;
Gastroscopy
;
Hematemesis
;
Humans
;
Intussusception
;
Jejunum
;
Mucous Membrane
;
Stomach
;
Stomach Ulcer
9.Effect of antiviral therapy in reducing perinatal transmission of hepatitis B virus and maternal outcomes after discontinuing them.
Kwang Il SEO ; Si Hyun BAE ; Pil Soo SUNG ; Chung Hwa PARK ; Hae Lim LEE ; Hee Yeon KIM ; Hye Ji KIM ; Bo Hyun JANG ; Jeong Won JANG ; Seung Kew YOON ; Jong Young CHOI ; In Yang PARK ; Juyoung LEE ; Hyun Seung LEE ; Sa Jin KIM ; Jung Hyun KWON ; U Im CHANG ; Chang Wook KIM ; Se Hyun JO ; Young LEE ; Fisseha TEKLE ; Jong Hyun KIM
Clinical and Molecular Hepatology 2018;24(4):374-383
BACKGROUND/AIMS: There have been numerous efforts to reduce mother-to-child transmission (MTCT) of hepatitis B virus (HBV) with antiviral agents during pregnancy. However, there are limited data regarding the outcomes of pregnant women after delivery. This study was performed to evaluate the efficacy of antiviral agents in preventing MTCT of HBV and maternal long-term outcomes. METHODS: The HBV-infected pregnant women treated with antiviral agents to prevent MTCT were retrospectively reviewed. Forty-one pregnant women who received telbivudine or tenofovir during late pregnancy (28-34 week) were analyzed. Hepatitis B virus surface antibody (HBsAb) positivity was tested in 43 infants after 7 months of birth. Eleven mothers were followed >1 year after delivery. RESULTS: The mean HBV DNA titer before antiviral therapy was 8.67 (6.60–9.49) log copies/mL, and the median age at delivery was 32 years (range, 22–40). Eleven patients were treated with tenofovir and 30 with telbivudine. The median duration was 57 days (range, 23–100), and the median HBV DNA titer at birth was 5.06 log copies/mL (range, 2.06–6.50). Antiviral treatments were associated with significant HBV DNA reduction (P < 0.001). Among 43 infants (two cases of twins), HBsAb was not detected in two, subsequently confirmed to have HBV infection. Biochemical flare was observed in two of 11 mothers followed >12 months, and an antiviral agent was administered. CONCLUSIONS: Antiviral treatment during late pregnancy effectively reduced MTCT. Long-term follow-up should be required in such cases. In addition, given that maternal biochemical flare occurred in 18% of mothers, re-administration of antiviral agents might be required.
Antiviral Agents
;
DNA
;
Female
;
Follow-Up Studies
;
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
;
Humans
;
Infant
;
Mothers
;
Parturition
;
Postpartum Period
;
Pregnancy
;
Pregnant Women
;
Retrospective Studies
;
Tenofovir