1.Three cases of nasal sinus foreign body caused by debris flow.
Yimei LI ; Zhu SHI ; Juxin WANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(9):495-496
A retrospective analysis of 3 patients with nasal sinus foreign body caused by debris flow admitted to our department. All of the three patients showed foreign odor and mucopurulent discharge in nasal cavity after the debris flow blast injury. CT examination found high density soft tissue shadow or calcification in the nasal sinus. All the diagnoses were nasal sinus foreign body in three patients. The nasal sinus foreign bodies was dislodged through endoscopic sinus surgery. Three patients are all well-healed.
Adult
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Female
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Foreign Bodies
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etiology
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Humans
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Male
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Paranasal Sinuses
2.Association of methionine synthase reductase gene polymorphism with unexplained recurrent spontaneous abortion
Qiannan GUO ; Shixiu LIAO ; Bing KANG ; Juxin ZHANG ; Ruili WANG ; Xuebing DING ; Weihua ZHANG
Chinese Journal of Obstetrics and Gynecology 2012;47(10):742-746
Objective To explore the relationship between the polymorphism of methionine synthase reductase(MTRR) A66G and the susceptibility to unexplained repeated spontaneous abortion (URSA).Methods Total of 200 Henan Han couples with URSA (URSA group) and 76 Henan Han healthy couples without URSA (control group)were enrolled in this study.Their MTRR A66G genotypes were determined by PCR restriction fragment length polymorphism (PCR-RFLP).Results (1) The allele frequencies of MTRR A66G:the frequencies of allele A and allele G in URSA group were 76.5% (153/200)in husband and 72.8% (146/200) in wife,23.5% (47/200) in husband and 27.2% (54/200) in wife,respectively.The frequencies of allele A and allele G in control group were 78.9% (60/76) in husband and 78.3% (59/76) in wife,21.1% (16/76) in husband and 21.7% (16/76) in wife,respectively.The frequencies of allele A and allele G were not significantly different between female and male subjects within the same experimental group (P > 0.05),and also there were not significantly different between the same gender subjects at URAS and control groups(P > 0.05).(2) The genotype frequencies of MTRR A66G:the frequencies of genotype AA,AG and GG in URSA group were 57.0% (114/200) in husband and 52.0% (104/200) in wife,39.0% (78/200) in husband and 41.5% (83/200) in wife,4.0% (8/200) in husband and 6.5% (13/200) in wife,prepectively.The frequencies of genotype AA,AG and GG in control group were 59.2% (45/76) in husband and 59.2% (50/76) in wife,39.5% (30/76) in husband and 38.2% (29/76) in wife;1.3 % (1/76) in husband and 2.6% (2/76) in wife,prepectively.The frequencies of genotype AA,AG and GG were not significantly different between female and male subjects within the same group (P > 0.05),and also there were not significantly different between the same gender subjects at URSA and control groups (P >0.05).(3) Combined genotype of couples:the combined genotype frequencies of GG + GG,GG + AG,GG +AA,AG + AG,AG + AA and AA + AA in URSA group were 1.0% (2/200),2.5% (5/200),6.0% (12/200),20.0% (40/200),38.0% (76/200),and 32.5 % (65/200),prepectively ; the combined genotype frequencies in control group were 0,1.3% (1/76),2.6% (2/76),17.1% (13/76),42.1% (32/76),36.8% (28/76),prepectively.The combined genotype analysis between the two groups were also not significantly different (P > 0.05).Conclusion The polymorphism of MTRR A66G gene was not associated with the susceptibility to URSA (P > 0.05),and so it was not the inherited genetic risk factor of URSA.
3.Effect of eletroacupuncture for Z syndrome without organic lesion and serum leptin.
Minghui LI ; Juxin SHEN ; Yongchun RUAN ; Luojie CAI ; Hua WANG ; Meixia SU ; Lixia YU
Chinese Acupuncture & Moxibustion 2016;36(4):376-378
OBJECTIVETo explore the effect and mechanism of electroacupuncture (EA) for Z syndrome without organic lesion (metabolic syndrome combined with obstructive sleep apnea hypopnea syndrome).
METHODSFifty-eight patients with Z syndrome were divided into three groups according to mild,moderate and severe degree. Acupuncture and EA were used at Daimai (GB 26), Zhongwan (CV 12), Xiawan (CV 10), Zusanli ST 36), Qihai (CV 6) and Huaroumen (ST 24), etc., once a day and five times a week. The treatment of ten times was a course, and two courses were acquired continuously. Sleep respiration monitoring (PSG) was done before EA and in one week after treatment respectively. Triacylglycerol (TG) fasting blood glucose (FBG) fasting insulin (INS) and serum leptin (Lep) were tested before and after treatment in the three groups.
RESULTSAfter treatment apnea hypopnea index (AHI) and the percentage of the time of arterial oxygen saturation (SaO₂) less than 90% taken in the total sleep time (SLT 90%) were improved apparently than those before treatment in the three groups (all P < 0.05). The levels of TG, FPG, INS and Lep were decreased after treatment in all groups (all P < 0.05).
CONCLUSIONEA can improve AHI and nocturnal hypoxia of Z syndrome, and the mechanism may be related to decreasing the indices of metabolism syndrome and leptin.
Acupuncture Therapy ; Adult ; Female ; Humans ; Insulin ; blood ; Leptin ; blood ; Male ; Metabolic Syndrome ; blood ; physiopathology ; therapy ; Middle Aged ; Sleep ; Sleep Apnea, Obstructive ; blood ; physiopathology ; therapy ; Treatment Outcome ; Triglycerides ; blood ; Young Adult
4.Effect of Yiqi Tongluo Anshen Recipe combined with statins on coronary blood flow and blood pressure in patients with coronary heart disease and hypertension
Jinxia WANG ; Juxin WANG ; Jing LIU ; Chang GENG
Journal of Clinical Medicine in Practice 2023;27(23):43-46,53
Objective To explore the effect of Yiqi Tongluo Anshen Recipe combined with statins on coronary blood flow and blood pressure in patients with coronary heart disease complicated with hy-pertension.Methods A total of 120 patients with coronary heart disease combined with hypertension were selected as study objects,and were divided into two groups according to treatment methods,with 60 patients in each group.The conventional group was treated with amlodipine tablets combined with atorvastatin calcium tablets,and the Anshen prescription group was treated with Yiqi Tongluo Anshen Recipe on the basis of the conventional group.The levels of Salusin-β,lipoprotein-associated phospho-lipase A2(LP-PLA2),high-sensitivity C-reactive protein(hs-CRP),pentamylin 3(PTX3),tumor necrosis factor-α(TNF-α)and blood pressure of the two groups were recorded before and after treat-ment,and the TIMI3 rate of coronary blood flow in myocardial infarction thrombolysis test(TIMI)and the adverse reaction rate during treatment were analyzed.Results The total effective rate of TCM syn-drome in the Anshen prescription group was higher than that in conventional group(P<0.05).After treatment,systolic blood pressure(SBP)and diastolic blood pressure(DBP)in two groups were lower than before treatment,and SBP and DBP in the Anshen prescription group were lower than those in the conventional group(P<0.05).The rate of coronary blood flow TIMI3 in the Anshen prescrip-tion group was higher than that in the conventional group(P<0.05).After treatment,levels of Sa-lusin-β,LP-PLA2,PTX3,hs-CRP and TNF-α in two groups were decreased compared with those before treatment,and levels of Salusin-β,LP-PLA2,PTX3,hs-CRP and TNF-α levels of in the Anshen prescription group after treatment were lower than those in the conventional group(P<0.05).There was no significant difference in the incidence of adverse reactions between the Anshen prescription group and the conventional group(P>0.05).Conclusion Yiqi Tongluo Anshen Recipe combined with statins in the treatment of coronary heart disease with hypertension can reduce the expression of related factors,improve coronary blood flow and the curative effect.
5.Effect of Yiqi Tongluo Anshen Recipe combined with statins on coronary blood flow and blood pressure in patients with coronary heart disease and hypertension
Jinxia WANG ; Juxin WANG ; Jing LIU ; Chang GENG
Journal of Clinical Medicine in Practice 2023;27(23):43-46,53
Objective To explore the effect of Yiqi Tongluo Anshen Recipe combined with statins on coronary blood flow and blood pressure in patients with coronary heart disease complicated with hy-pertension.Methods A total of 120 patients with coronary heart disease combined with hypertension were selected as study objects,and were divided into two groups according to treatment methods,with 60 patients in each group.The conventional group was treated with amlodipine tablets combined with atorvastatin calcium tablets,and the Anshen prescription group was treated with Yiqi Tongluo Anshen Recipe on the basis of the conventional group.The levels of Salusin-β,lipoprotein-associated phospho-lipase A2(LP-PLA2),high-sensitivity C-reactive protein(hs-CRP),pentamylin 3(PTX3),tumor necrosis factor-α(TNF-α)and blood pressure of the two groups were recorded before and after treat-ment,and the TIMI3 rate of coronary blood flow in myocardial infarction thrombolysis test(TIMI)and the adverse reaction rate during treatment were analyzed.Results The total effective rate of TCM syn-drome in the Anshen prescription group was higher than that in conventional group(P<0.05).After treatment,systolic blood pressure(SBP)and diastolic blood pressure(DBP)in two groups were lower than before treatment,and SBP and DBP in the Anshen prescription group were lower than those in the conventional group(P<0.05).The rate of coronary blood flow TIMI3 in the Anshen prescrip-tion group was higher than that in the conventional group(P<0.05).After treatment,levels of Sa-lusin-β,LP-PLA2,PTX3,hs-CRP and TNF-α in two groups were decreased compared with those before treatment,and levels of Salusin-β,LP-PLA2,PTX3,hs-CRP and TNF-α levels of in the Anshen prescription group after treatment were lower than those in the conventional group(P<0.05).There was no significant difference in the incidence of adverse reactions between the Anshen prescription group and the conventional group(P>0.05).Conclusion Yiqi Tongluo Anshen Recipe combined with statins in the treatment of coronary heart disease with hypertension can reduce the expression of related factors,improve coronary blood flow and the curative effect.