1.Clinical observation of conventional surgical treatment of tibial plateau fractures and traditional Chinese medicine intervention
Juqin HONG ; Guobiao PAN ; Wei WANG
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):64-65
Objective To explore the clinical effect of conventional surgical treatment of tibial plateau fractures and traditional Chinese medicine intervention. Methods Sixty-eight patients with tibial plateau fractures who had received medical treatment from Hangzhou Cancer Hospital (May 23, 2015 to May 23, 2016) were randomized to the surgical group and the combined group as the subjects of this study. 34 patients in the operation group were treated with surgical treatment. 34 patients in the combined group were treated with traditional Chinese medicine on the basis of operation. The clinical efficacy and knee function scores of the patients with tibial plateau fractures were compared. Results The total effective rate was 91.18% in the combined group, which was significantly higher than that in the operation group (73.53%) (P<0.05). The knee function score of the combined group was (25.36±3.85) The operation group (21.24 ± 3.89) was significantly higher (P<0.05). Conclusion The intervention of traditional Chinese medicine combined with traditional Chinese medicine can significantly improve the function of knee joint in patients with tibial plateau fractures.
2.Nosocomial Infections of Inpatients: A Clinical Investigation and Analysis with Large Sample Size from 2000 to 2004
Zhihui YANG ; Jing MU ; Juqin RUAN ; Hong LIU ; Fanghui CHEN ; Bing ZHAO
Chinese Journal of Nosocomiology 2006;0(07):-
OBJECTIVE To investigate the clinical feature of nosocomial infections in general hospital,based on which effective methods are taken.METHODS An analysis was made on the basis of the survey,the data came from 73 690 hospitalized cases from 2000 to 2004.Bacterium appraise adopted French VITEK-32 fully automatic Expression.RESULTS Their prevalence rate was 5.34%,the main infection site was lower respiratory tract,and followed by upper respiratory tract and urinary tract.Among bacteria isolated from clinical cases,49.24% were G~-,(25.30%) were G~+,and 25.46% were fungi.The proportion of conditional bacteria showed an increasing trend from 2000 to 2004.CONCLUSIONS The conditional bacteria show an increasing trend in the nosocomial(infections.) Strengthening the nosocomial infection management,treating underlying disease actively,lessing(invasive) process,supervising towards bacteria,and using antibacterial drug rationally are effective methods to(reducing) the rate of nosocomial infections.
3.Dynamic changes of tear fluid matrix metralloproteinase-9 within 1 year after laser in situ keratomileusis.
Hongpei JI ; Aiwei CHEN ; Weiwei ZHANG ; Hong GU ; Zhiling ZHANG ; Juqin FU
Journal of Southern Medical University 2014;34(8):1079-1082
OBJECTIVETo investigate the dynamic changes of matrix metalloproteinase-9 (MMP-9) level in tear fluid within 12 months after laser in situ keratomileusis (LASIK).
METHODSTwenty-two myopic patients undergoing uneventful LASIK were enrolled in this study. Tear fluid samples were collected from the patients for measurements of MMP-9 level using Western blotting preoperatively, at 7 and 14 days, and at 1, 2, 3, 6, and 12 months after the surgery.
RESULTSMMP-9 concentrations in the tear fluid of post-LASIK patients showed a time-dependent variation pattern. MMP-9 reached its peak level in the tear fluid at 14 days postoperatively, which was 2.70 times the preoperative level; it gradually decreased thereafter but was still 1.38 times the preoperative level at 12 months after the surgery.
CONCLUSIONSMMP-9 concentrations in the tear fluid of post-LASIK patients show a time-dependent variation pattern and remains higher than the preoperative level even at 12 months after the surgery, suggesting that corneal wound healing after LASIK lasts for more than 12 months.
Cornea ; Humans ; Keratomileusis, Laser In Situ ; Matrix Metalloproteinase 9 ; chemistry ; Myopia ; surgery ; Postoperative Period ; Prospective Studies ; Tears ; chemistry ; Wound Healing