Objective To study the clinical application of dynamic monitoring of mainstream endtidal carbon dioxide in neonatal respiratory distress syndrome.Methods All of 23 premature neonates diagnosed with NRDS and placed on mechanical ventilation were admitted in this study.Their PetCO_2 was continuously monitored and paired with PaCO_2 at 112 different time points.The correlation between PetCO_2and PaCO_2 was compared.Results This study showed that the average PaCO_2 measured for 112 times was(38.2±5.6)mm Hg(1 mm Hg=0.133kPa)and the corresponding PetCO_2 was,(32.4±4.9)mm Hg;it also showed that PetCO_2 was positively correlated with PaCO_2 and PetCO_2 was even more closely correlated with PaCO_2 in infants with second degree of NRDS than in patients with third and fourth degree of NRDS.Conclusions Dynamically monitoring mainstream PetCO_2 is applicable in mechanically ventilated premature infants with NRDS,it can accurately reflect the level of PaCO_2;Thereby reducing the blood gas analysis,thus reducing the suffering of nursing workload and children.But it has limited significance in cases of severe NRDS.

ObjectiveTo discuss the effects of targeted nursing intervention on pregnancy outcome and neonatal weight in patients with gestational diabetes mellitus (GDM). MethodsTotally 108 GDM patients treated in our hospital from July 2017 to February 2019 were selected and divided into intervention (n=54) and control (n=54) groups according to the random number table. Patients in the control group received conventional nursing care, while patients in the intervention group received targeted care on this basis. Patient＇s blood glucose level, pregnancy outcome, neonatal weight and satisfaction with nursing before and after nursing care were compared between the two groups. ResultsThere was no statistically significant difference in blood glucose levels between the two groups before nursing intervention (P＞0.05). Fasting blood glucose, 2 h postprandial blood glucose and glycosylated hemoglobin levels were lower after nursing intervention in both groups. The levels of the intervention group were even lower than those of the control group, and there were statistically significant differences between the two groups (P＜ 0.05). The incidence of malignant pregnancy outcome and neonatal complications of the intervention group were lower than those of the control group after nursing intervention, and patient＇s satisfaction with nursing was higher in the intervention group than in the control group, and there were statistically significant differences between the two groups (P＜ 0.05). ConclusionsTargeted nursing intervention can effectively reduce blood glucose levels of GDM patients and the incidence rate of adverse maternal and neonatal outcome, and improve patient＇s satisfaction, which is worth promoting in clinical practice.