1.Endoscopic mucosal resection for sub-pedicle or non gastrointestinal tract polyps in primary hospital
Chinese Journal of Postgraduates of Medicine 2014;37(21):23-25
Objective To evaluate the efficacy of endoscopic mucosal resection (EMR) for sub-pedicle or non gastrointestinal tract polyps in primary hospital.Methods Retrospectively analyzed the data of 43 patients of EMR from November 2011 to December 2013.Results In 43 patients,84 lesions were resected,2 cases of hemorrhage during EMR immediately,1 case delaying hemorrhage,no complications such as perforation or infection occurred.Length of operation time was (6.73 ± 1.24) min per focus,hospital stay was (5.50 ± 0.61) d,there was no recurrence in any patient by endoscope during a follow-up of 6-24 months.Conclusions The technique of EMR is simple,less trauma,no pain,fast recovery for patients.As long as selecting suitable patient,EMR can be carried out widely in primary hospital.
2.Association of COX_2 with P38MAPK in late phase of ischemic preconditioning in rat cardiomyocyte
Journal of Chongqing Medical University 1986;0(04):-
0.05).Conclusion:In late phase of ischemic preconditioning,the P38MAPK activity and COX 2 expression increase significantly in rat cardiomyocyte,P38MAPK mediated COX 2 expression,and may be an up-stream of COX 2.
3.Development of ischemic preconditioning model of cultured neonatal rat cardiomyocyte in vitro
Journal of Chongqing Medical University 1987;0(01):-
0.05).Conclusion:The isehemic preconditioning model in vitro may be induced easily by oxygen deprivation in cultured neonatal cardiomyocytes,and can be used to further studyon the mechanism of the late phase of preconditioning.
4.Association among COX_2, iNOS and p38MAPK in late phase of preconditioning in rat cardiomyocytes
Chinese Journal of Pathophysiology 2000;0(10):-
0.05). The LDH was lower ,and cell viability was higher in group IPC than those in control group. The LDH was higher ,and cell viability was lower in grou p SMT, group NS 398 and group SB than those in group IPC. CONCLUSIONS: In late p hase of preconditioning ,the p38MAPK activity and expression of iNOS and COX 2 increase significantly in rat cardiomyocytes, activited p38MAPK mediates iNOS ,then promotes COX 2 expression.
5.Tension-free herniorrhaphy using Kugel patch in groin hernia
Chinese Journal of Primary Medicine and Pharmacy 2006;0(01):-
Objective To review the clinical experiences of Kugel herniorrhaphy.Methods Fifty-eight patients with sixty-two groin hernia were performed with Kugel patch.Results Mean operating time was 25min.The patients could walk in fifty hours and work in five days after operation,respectively.No recurrence or discomfort was found during a fellow-up of 1~36 months.Conclusions Kugel herniorrhaphy is a minimally invasive,tension-free,almost sutureless,and total inguinal repair.The leaning curve is about 10 Kugel herniorrhaphy.
6.Role and mechanism of Kupffer cells in anti-tumor immunity of hepatocellular carcinoma
Wuyong YU ; Junyong ZHANG ; Jianping GONG
International Journal of Surgery 2016;43(4):285-288,封4
As the biggest macrophage cells population in human body and the most important immune cells in the liver,Kupffer cells play a very important role in infection,inflammation,lipid metabolism and liver transplantation,and regulates various physiological and pathological processes.However,little is known about the role and mechanism in the tumorigenesis and tumor progression of Kupffer cells which as a kind of such important immune cells.In this paper,we summarized published researches and our experimental results about Kupffer cells,and reviewed the relationship between Kupffer cells and hepatocellular carcinoma from aspects of phagocytosis,secretary and antigen presentation.We hold that,at the early age of liver diseases,Kupffer cells inhibit tumorigenesis of hepatocellular carcinoma by its functions of phagocytosis,secretary and antigen presentation;however,when inflammation persists,Kupffer cells could induce tumorigenesis of hepatocellular carcinoma by secretary mechanism.
7.Effects of individualized nursing on the negative mood and quality of life of patients with hemoptysis
Lian LI ; Junyong WU ; Caifeng CHEN
Chinese Journal of Practical Nursing 2010;26(35):14-16
Objective To study the effects of individualized nursing on the anxiety, depression mood, quality of life of patients with hemoptysis. Methods Sixty patients with hemoptysis were randomized into the intervention group and the control group with 25 cases in each. The control group received single conventional therapy while the intervention group was given individualized nursing intervention besides the conventional therapy. Using SDS, SAS and SF-36 Life Quality Measuring Scale to evaluate the effects of the patients in both groups on admission and prior to discharge. Results The scores of anxiety and depression among the intervention group were lower than those of the control group after intervention.The dimensions of quality of life besides the physical function and bodily pain in the intervention group were significantly different after intervention. Conclusions The individualized nursing intervention can improve quality of care, the state of anxiety, depression and the quality of life of patients with hemoptysis.
8.THE CHANGES OF SERUM PROTEIN IN ELECTROPHORESIS IN UREMIA AND NEPHROTIC SYNDROME PATIENTS
Junyong ZHAO ; Xueliang FENG ; Zhicheng LIU
Journal of Xi'an Jiaotong University(Medical Sciences) 1981;0(02):-
It is reported in this article that ?-lipoprotein and partial ?_1-and X_2-globulin in scrum are apparently lower, but haptoglobin and ?-lipoprotein are apparently higher by polyacryamide gel clectrophoresis in 50 cases of uremi(?) patients, and that albumin and partial ?_1-and ?_2-globulin in scrum are apparently lower, but partial ?_2-globulin and ?-lipoproteinare apparently higher by polyacryamide gel clectrophoresis in 50 cases of nephrotic syndrome patients. The mechanism and clinical significance of these changes are discussed.
9.The procedure for the prolapse and haemorrhoids in the management of severe haemorrhoids
Junyong CHEN ; Ronglun YU ; Yuangang LIN
Chinese Journal of Primary Medicine and Pharmacy 2006;0(07):-
Objective The aim of this study was to demonstrate the effectiveness of the procedure for the prolapse and haemorrhoids in management of haemorrhodis.Methods Analyze the data of sixty-two consecutive patients with third or fourth degree hameorrhoids treated by the procedure for the prolapse and haemorrhoids.Results The median surgical time was 15 minutes,the median postoperative hospital stay was 2.3 days,median time to retum to normal activity was 6.8 days.Five patients need postoperative analgesic,on postoperative bleeding,eighteen patients had acute urinary retention.Fifty-six(90.32%) of the patinets had been followed up to 6 weeks,fifty patients were satisfied with the results of the procedure.Conclusion The procedure for the prolapse and haemorrhoids is a safe and effective treatment for severe haemorrhoids and with the advantages of shorter time of operation and inpatient stay,earlier return to normal activity.
10.Determination of hesperidin and salvianolic acid B in Xiaopikang Capsule by HPLC
Junxiang WANG ; Dongying WANG ; Junyong LI
Chinese Traditional Patent Medicine 1992;0(09):-
AIM: To determine the contents of hesperidin and salvianolic acid B in Xiaopikang Capsule(Folium Citri reticulatae,Radix et Rhizoma Salviae miltiorrhizae,etc.) by HPLC. METHODS: The HPLC system consisted of Diamonsil C_(18) column(250 mm?4.6 mm,5 ?m), metanol-acetonitrile-formicacid-water(30∶10∶1∶59) mixture as mobile phase,detection wavelength at 284 nm,flow rate of 1.0 mL/min. RESULTS: The ca-(libration) curves of two ingredients were linear within the ranges of 0.22 ?g-2.2 ?g(r=0.999 6,hesperidin),(1.62 ?g-10.2 ?g)(r=0.999 9,salvianolic acid B),respectively.The average recoveries of hesperidin was(98.9%)(RSD=1.60%),salvianolic acid B for 99.02%(RSD=0.97%). CONCLUSION: The method is rapid,sensitive and accurate.