The performance evaluation of science and technology management personnels could stimulate their enthusiasm and advance the development of science.In this article,a 3-dimensional model was set up based on the evaluating criteria,the evaluating objects & the familiarity between the appraiser and the objects,which was simplified from several complicated factors necessary in the process of evaluation.Compared with the traditional methods,this 3D model sheds more light on choosing the critical factors,which helps improve the accuracy and rationality of scientific evaluation.

Military medicine has to restructure itself to meet military needs and e-Science patterns of the information age.This restructuration is known asinformationization of military medicine ( IMM).IMM is a process of vision refresh-ing into information thinking, mission expansion to the information field and paradigm shift to normal forms of information. The result is the emergence of military med-information technologies, military med-information research fields, and military med-informatics disciplines.

Taking Science Citation Index Expanded (SCI-Expanded) as information source,and using methods of bibliometric analysis,Chinese Medicine international co-authored articles which published from 1998 to 2010 were statistically analyzed on publish year,document growth,active fields,etc.,aiming to look for status and trends in International Collaboration of the Traditional Chinese Medicine,and to be a reference for researchers.

Objective To study the diagnostic value of computed tomographic virtual endoscopy versus electronic colonoscopy for colon cancer in elderly patients.Methods The 69 cases of elderly patients with colon cancer received CTVE and electronic colonoscopy before surgery to compare achievement rates,sensitivities,and endoscopy coincidence rate with pathologic classification between the two methods.Results For a definite diagnosis of colon cancer in elderly patients,achievement ratio was 98.6％ (68/69) in CTVE and 62.3％ (43/69) in electronic colonoscopy(x2 =14.72,P＜ 0.05);sensitivity was 95.6％ (65/68) in CTVE and 97.7％ (42/43) in electronic eolonoscopy(x2=0.003,P ＞ 0.05);endoscopy coincidence rate with pathologic classification was 95.4％ (62/65) in C-TVE and 95.2％(40/42) in electronic colonoscopy.Conclusions CT virtual endoscopy may be one of examination methods in elderly patients with colon cancer.

This study was aimed to search and analyze patents of Chinese herb published both at home and abroad in 2010. The Derwent World Patents Index (DWPI) was used as database source. A total of 8 704 Chinese herb patent records were retrieved. And the geographical distribution was concentrated in China. The technological field was mainly on hepatitis, liver cirrhosis, lower back pain, cough and other diseases. Innovations on formulation and preparation method also required special attention. In addition, through the analysis on patent attribution agency, some well-known Chinese enterprises, who aim to gain the initiative in specific technical areas, have actively applied a number of patents in specific areas.

OBJECTIVE To investigate the site of nosocomial infection in ICU,distribution and resistance of bacteria in order to make the intervention strategy.METHODS Antimicrobial susceptibility of pathogenic bacteria isolated from nosocomial infection patients in ICU from Jul 2006 to Jul 2008 was performed by Kirby-Bauer method.RESULTS The main pathogens of nosocomial infection in ICU were Gram-negative organisms(48.09%),Gram-positives(38.93%),and fungi(12.98%).The most common pathogens were Staphylococcus aureus,Acinetobacter baumannii,Pseudomonas aeruginosa,fungi,and S.haemolyticus.All strains of S.aureus and S.haemolyticas were antimicrobial sensitive to vancomycin,teicoplanin and linezolid.All A.baumannii strains were antimicrobial sensitive to cefoperazone/sulbactam.They were resistant to other antimicrobial agents.CONCLUSIONS Gram-negative organisms are the main pathogenic bacteria of nosocomial infection in ICU,but the percentage of Gram-positives and fungi is increasing,S.aureus is the most main pathogenic bacterium of nosocomial infection in ICU.S.haemolyticus is also a main pathogenic bacterium.The pathogenic bacteria of nosocomial infection in ICU are highly resistant to the most antimicrobial agents.

This survey included 59 secondary researches of traditional pharmaceutical patent literatures. The analysis was made on statistical indicator of the amount of annual papers, authors, institutions, published journals and re-search contents. The survey revealed that in the field of traditional Chinese medicine (TCM), the number of sec-ondary research of patent literature was on the increase, and the degree of concern of TCM patent was far more than others. This survey not only assisted the understanding of current condition of TCM patent literatures, but also held its development trend in order to apply it in the studies.

New registry classifications of chemical drugs redefined the concepts of new drugs and generic drugs. New drugs emphasize the international innovation including innovate new drugs and modified new drugs. Modified new drugs are improvement of drugs already on the market to achieve superior efficacy. With the advantages of high success rate,high return,low risk and long life cycle,modified new drugs have become the mainstream of new drugs research and development in the world. Modified new drugs R&D in China should be based on clinical demand and focused on the differentiation research in order to obtain new preparations with signif-icant clinical advantages to better serve the clinical practise. This paper states the concept and characteristics of modified new drugs in China,makes case analysis and shares the development history of blockbuster modified new drugs in the world,clarifies the opportuni-ties and challenges and provides ideas for the future development of modified new drugs in China.

Objective To investigate the clinical application of 99mTc-DTPA renography in evaluating the glomerular filtration rate (GFR) in living donor kidney transplantation and to assess the dependence of GFR on age and gender in living kidney donors. Methods There were 212 consecutive potential donors in the study. The potential donor evaluation process included as follows: general health status, liver and kidney ultrasound, hepatitis virus infection and HLA-DR matching. If the results met the general requirements for the donor selection criteria, the GFR was measured using the 99mTc-IDTPA renography according to standard procedure (gates method). The GFR ≥ 1.33 ml/s was considered normal, ＜ 1.17 ml/s was defined as the lower limit for donor GFR, and 1.17 ml/s ≤GFR ＜ 1.33 ml/s further underwent measurement of creatinine clearance (CCr). If the CCr was normal, the GFR was considered normal, and otherwise, potential donors gave up kidney donation.All the donors meeting the donor selection criteria were divided into four age groups. On the other hand, the total donors were divided into the groups aged ＞ 55 years and aged ≤ 55 years. The impact of gender and age on GFR was evaluated preoperation due to age-related changes and gender using Kendall's tau-b correlation coefficient. Results In 212 potential donors, 137 cases had a GFR ≥ 1.33ml/s, 55 cases 1.17 ml/s ≤ GFR ＜ 1.33 ml/s and 20 cases GFR ＜ 1.17 ml/s. Thirty-one cases of potential donors with 1.17 ml/s ≤ GFR ＜ 1.33 ml/s gave up kidney donation due to abnormal CCr or other security considerations. 161 (56 females, 105 males) were qualified as successful donors, and the donor age was 42. 91 ± 11.90 years (range 20 to 62 years). The preoperative total GFR (ml/s) in living kidney donors was calculated as 1.51 ± 0.22 for males, it was 1.45 ± 0.18 for females respectively (P＞0.05). Among the four age groups, there was no significant difference in GFR (P＞0.05). The GFR in the donors aged ＞ 55 years and aged ≤ 55 years was 1.48 ± 0.22 and 1.49 ±0.17 respectively (P＞0.05). Correlation analysis revealed that the GFR in all the donors was not related with age (r = -0. 033, P = 0. 69). Also, there was no correlation between age and GFR in men and women(r= -0.053, P=0.571; r= -0.019, P=0.754). Conclusion 99mTc-DTPA renography is reliable and reproducible for the determination of GFR in living kidney donors. In view of acute donor shortage and if properly screened, kidneys with 1.17 ml/s≤ GFR ＜ 1.33 ml/s can be used without increasing the risk to donor. The GFR is not correlated with the age and gender.

For the effectiveness in disease treatment and prevention, traditional medicine (TM)has been widely used around the world. Many governments have accepted TM as part of their health system. Meanwhile, the regulation became strict. This paper analyzed the regulation mode of TM and Complementary & Alternative Medicine (CAM) in foreign countries. The regulation mode mainly included: independent legislation for TM, comprehensive legislation as CAM, and self-discipline regulation by trade association. We also analyzed the existing problems and prospected the developing trends in future.