1.Clinical characteristics of acute myocardial infarction with leukocytosis and their significances
Clinical Medicine of China 2000;0(11):-
Objective To study the relationship between the white blood cell (WBC) count of peripheral blood at the early stage of acute myocardial infarction (AMI) and the prognosis.Methods 100 cases of AMI were divided into normal WBC counts and elevated WBC counts group.Clinical characteristics of the two groups were compared.Results The cases of AMI with leukocytosis is apt to complicate left ventricular failure,arrhythmia and excitable hyperglycemia.The peak value of CK and ECG QRS scoring as well as mortality were elevated.Conclusion The WBC has an important prognostic significance in AMI.
2.Advances in tissue and organ engineering
Yang WU ; Junsheng YE ; Zheng ZHANG
Chinese Journal of Hepatobiliary Surgery 2012;18(10):805-808
Tissue engineering has evolved as a dynamic research field that encompasses multidisciplinary approaches involving cytology,material science,bioreactor engineering,and medicine.The overarching goal is to construct human tissue and organs in the laboratory for tissue regeneration or replacement.It offers a potential solution to the donor shortage in organ transplantation and to the difficulties in regenerative medicine.The basic components for tissue engineering include seed cell selection,bio-scaffold construction,and ex vivo tissue formation via a bioreactor. Over the past decade,tremendous progress has been made in bioengineering cartilage,trachea,urinary bladder,heart valve and endocrine tissues. However,there remain significant challenges in creating complex and human-sized tissues and organs for clinical use.In this article,we review the basic components and strategies for bioengineering organs. We attempt to provide an overview of current progress and challenges in developing organ-level tissue engineering and in the successful translation of bioengineered tissue and organ products into daily clinical practice.
3.Analyzing the Benefit Equity in China’s Basic Health Insurance System
Zhongliang ZHOU ; Jianmin GAO ; Junsheng ZHANG
Chinese Health Economics 2013;(7):21-23
Objective: To analyze the equity of benefit which residents with different income get from Urban Employee Medical Insurance ( UEMI) and New Rural Cooperative Medical System (NCMS). Methods: Data used in this study is based on the forth household health service survey in Shanxi province. The indirectly standardization method and concentration index were employed to analyze the horizontal inequity index of benefit rate and benefit degree. Results:The horizontal inequity index of benefit rate and benefit degree in UEMI are 0.0524 and 0.0025, and the horizontal inequity index of benefit rate and benefit degree in NCMS are 0.2312 and 0.3228. Conclusion: The urban residents get the equal benefit from UEM, and there were pro-rich horizontal inequities of benefit rate and benefit degree in NCMS.
4.Introduction of a new invented spondylolisthesis reduction system for treatment of lumbar spondylolisthesis
Dacheng ZHU ; Qiang ZHANG ; Junsheng CHEN
Orthopedic Journal of China 2006;0(23):-
[Objective]To assess the effect of a new invented spondylolisthesis reduction system:elevating-pull reduction system for surgical treatment of lumbar spinal spondylolisthesis associated with isthmic spondylolysis.[Method]Sixty-two patients with lumbar spinal spondylolisthesis were treated with elevating-pull reduction system combined with SRS(spondylolisthesis reduction system),after surgery the patients were evaluated for symptom improvement,intervertebral bone graft fusion,and internal fixation.[Result]The patients were followed up from 1 to 6 years(average 2 years and 5 months) in 62 patients.According to the criterion,excellent results were in 43 patients,good in 16,moderate in 3.No patient showed worse.No internal fixation loosening and breakage were found.[Conclusion]The new invented spondylolisthesis elevating-pull reduction system combined with SRS are more effective and reliable,especially for those osteoporosis patients and serious cases,the reduction and fixation are more effectively.In this procedure the pedicle entrance mouth can be seen straightly and the pedicle screw is inserted more easily.It can prevent the nerve injury,save the operation time,reduce the blood lossing,and excellent outcome can be obtained.
5.Clinical study on treatment of Jing Kang Yin decoction for cervical spondylosis neuiodynia
Junsheng CHEN ; Jidong ZHANG ; Fuzhang GU
Orthopedic Journal of China 2006;0(17):-
[Objective]To observe the clinical therapeutic effect of Jing Kang Yin decoction on nerve-root cervical spondylosis.[Method]152 patients with Cervical Spondylosis neuiodynia were selected and divided into two groups;treatment group with Jing kang Yin decoction(87 cases) and control group with Jingfukang(65 cases).Pain degree(VAS methods),hemorheological indexes,serum cytokine IL-10 and adhesion molecule were observed before and after treatment and the clinical therapeutic effect of two groups were compared.[Result]Pain scores of two groups were lower after treatment than treatment before(P
6.Radiographic Index Analysis of the Cervical Spine Curvature and the Range of Flexion-extension
Junsheng MAO ; Huayi ZHANG ; Yuhua LU
Journal of Chinese Physician 2001;0(02):-
Objective To provide a new method for measuring cervical spine curvature and the range of flexion-extension and to analyse the radiographic features of the cervical degeneration.Methods The study included 78 patients with cervical spondylosis,90 patients with neck symptoms and 86 normal volunteers.The three groups were compared with each other by the indexes of the cervical spine curvature and the range of flexion-extension.Results There was significantly difference among three groups in the cervical vertebrae lordosis at neutral position.The range of flexion-extension of cervical spondylosis in the patients was smaller than that of the normal volunteers.Conclusions The index method can accurately depict the cervical spine curvature and the range of flexion-extension.There is definitive order in symptom appearance,alterations of physiologic curvature and flexion-extension in the cervical degeneration.
7.Statistical analysis on the publication of SCI papers written by the staff of Third Military Medical University from 2010 to 2012 and discussion of assessment with SCI
Zhu ZHANG ; Jun DENG ; Hongjun ZHANG ; Yong YANG ; Junsheng JI
Chinese Journal of Medical Science Research Management 2014;27(6):693-695
The quality and quantity of published SCI papers written by the Third Military Medical University from 2010 to 2012 were analyzed to provide information for the scientific research administration.The problems of assessment with SCI was discussed.At last,suggestions were proposed to improve scientific research administration,innovation ability and scientific and technological level.
8.THE PROTECTIVE EFFECTS OF VITAMIN C ON OXIDATIVE DAMAGE OF ALEVEOLAR MACROPHAGE INDUCED BY Ni2O3 IN VITRO
Jing ZHANG ; Jun ZHANG ; Hongjun SHI ; Junsheng GUO
Acta Nutrimenta Sinica 2004;0(06):-
Objective:To study the effects of vitamin C (VC) on the injury of alveolar macrophages exposed to Ni2O3 in vitro and the expression of inducible nitric oxide synthase (iNOS). Method:The alveolar macrophages were cultured with exposure to Ni2O3 in vitro. Meanwhile,VC with different concentrations (25,50 and 100 ?mol/L) were added to the medium, respectively. The cell activity,nitric oxide(NO),reactive oxygen species (ROS), malondialdehyde (MDA) and activities of SOD, GSH-Px,CAT and iNOS were detected. iNOS mRNA expression was detected by using RT-PCR. Results:VC could decrease mortality and increase survival activity of alveolar macrophages. VC could also decrease ROS,NO and NOS activity,increase SOD,GSH-Px, CAT activities and downregulate the expression of iNOS mRNA. Conclusion:The lipid peroxidation of alveolar macrophage could be induced by Ni2O3. VC could downregulate the expression of iNOS mRNA and reduce the production of ROS and NO through increasing the activity of antioxidative enzymes and antagonize the oxidative damage induced by Ni2O3.
9.Clinical outcomes after redo coronary artery bypass grafting
Junsheng MU ; Jianqun ZHANG ; Deville CLOUD ; Giorgio COLONNO
Chinese Journal of Thoracic and Cardiovascular Surgery 2010;26(1):23-25
Objective Evaluate the clinical outcomes of redo coronary revascularization performed with CABG techniques. Methods During the past 10 years, 51 patients (2.5% in the patients who underwent CABG and OPCABG) received redo coronary revascularization in our hospital. The period between the first and the redo surgeries was ( 15.1±5.8)years. Two different procedures were performed with or without cardiopulmonary bypass for the redo CABG: off-pump procedure (OPCABG) in 10 patients and on-pump procedure (CABG) in 41 patients. Two types of surgical approaches were used: me-dian sternotomy in 43 patients and left thoracotomy in 8 patients. Results Respiratory failure requiring mechanical ventilation occurred in 3 of the 51 patients after the operation, as compared with none in the patients who underwent OPCABG. The mean duration treated in the ICU was (2.2±0.7 ) days and that of hospital admission was( 9.2±2.4) days. Two patients (3.9%)died in hospital, one ease was in the off-pump group and the other was in the on-pump group. The causes of death were thought to be acute myocardial infarction with low output syndrome in 1 case and severe respiratory failure in the other. Complications occurred in 11 patients, including re-thoracotomy for hemostasis in 1 patient, respiratory failure in 3 patients and other complications 7. Postoperative EF was 0.60±0. 06. Complete revascularization was achieved in 44 patients, 6 patients in the offpump group and 38 patients in the on-pump group. Partial revascularization was observed in the additional 7 patients. Conclusion Redo CABG performed with or without cardiopuimonary bypass may provide favorable effects with acceptable safety profile and complete revascularization is achievable.
10.Application of the system safety theory in medical safety management
Junsheng JI ; Yong ZHANG ; Hao WU ; Jiang LIU
Chinese Journal of Hospital Administration 2009;25(5):328-331
A description of the concept,origin and development,and key contents of the system safety theory,and an analysis of the presence and future of China's medical safety management,holding that such a theory enjoys a promising perspective in medical safety managemenL Medical safety management needs to follow such a theory as fl guideline,and its principles to set system safety objectives,and to determine the scope of the safety system_By building a comprehensive feedback mechanism,clarifying the responsibility borders and advocating a safety culture,medical safety management can be significantly upgraded.