1.Characteristics of Yersinia enterocolitica in Ningxia,China,2008-2013
Xiang LIU ; Yangbo LIU ; Bangcheng GUO ; Liqiong YAN ; Mei SHEN ; Qiong WEI ; Junrong LIANG ; Xin WANG ; Qiong HAO
Chinese Journal of Zoonoses 2015;(3):260-263,271
We investigated the distribution characteristics of Yersinia enterocolitica in Ningxia ,China .In accordance with the requirements of the National Yersinia enterocolitica Disease Monitoring Scheme ,Y .enterocolitica were isolated from differ‐ent kinds of specimens collected in Ningxia in 2008 to 2013 .Then they were serotyped and detected for virulence gene and ana‐lyzed the pulsed‐field gel electrophoresis (PFGE) in Chinese CDC .It was found that 173 strains were isolated from various types of 9 643 specimens ,and the detection rate was 1 .79% .There were statistical differences among detection rates in differ‐ent years and in different specimens (P<0 .01) .Pathogenic serotypes O∶3 and O∶9 carried ail gene and ystA gene were de‐tected from specimens of pigs and diarrhea patient .Non‐pathogenic serotypes O∶5 and O∶8 and non‐typeable strains didn't carry ail gene and ystA gene ,and also can't be detected from swine ,cattle ,sheep ,chickens and dogs .In conclusion ,Y .en‐terocolitica was widely distributed in Ningxia and pigs were the dominant animal host .In all pathogenic serotypes ,the highest proportion was O∶3 following by O∶9 .It was no time and regional difference in the distribution of that in Ningxia ,China .
2. Etiological study of diarrhea in children under 5 years old in Dongcheng district of Beijing
Lianjun WANG ; Ying ZHOU ; Liang QI ; Junrong LIANG ; Hao SUN ; Baolin XU ; Jing WANG ; Xin WANG ; Huaiqi JING
Chinese Journal of Preventive Medicine 2018;52(9):936-940
Objective:
To analyze the etiological characteristics of infectious diarrhea among people under 5 years old in Dongcheng District, Beijing.
Methods:
The age, time of infection, clinical symptoms and laboratory test results of the cases who didn't used antibiotics within 3 days in the second maternal and child health care hospital were collected from 2012 to 2015, through the information management system of infectious disease monitoring technology platform. To compare the detection rate of virus and bacteria in children with different sex, time and age,and the difference of clinical characteristics between virus detection group and bacteria detection group by chi square test.
Results:
1 977 cases of infectious diarrhea were collected, the median of the month age (
3.Effects of Niaoduqing Granule on quality of life and TGF- β1/Smad signalling in chronic renal failure rats received peritoneal dialysis
Jinxiu CHENG ; Junrong HAO ; Linlin WANG ; Cuilan LIU ; Xing PAN ; Sheng-Jun LIU ; Hua LIU
The Journal of Practical Medicine 2018;34(5):725-728
Objective To investigate the effect of Niaoduqing Granule on the quality of life and the activa-tion of TGF-β1/Smad signalling in chronic renal failure rats received peritoneal dialysis. Methods Thirty SD rats were used to establish peritoneal dialysis models and were randomly divided into the model group(group M),the low dose group(group L),and the high dose group(group H).The dosage of group L and group H was 2 and 4 g/(kg·d),respectively. The body mass,the number of independent activities,the index of renal hypertrophy, Scr,BUN,experssion of TGF-β1 and p-Samd2/3 were determined. Results The body weight growth rate was shown decreased as follows:group N>group H>group L>group M.The number of spontaneous activity of group M decreased significantly than those in other groups. Scr,BUN and kidney hypertrophy index were significantly different among the four groups.Compared with group M,BUN,Scr,kidney hypertrophy index,levels of TGF-β 1 and p-Samd2/3 were significantly decreased in group L and H. Levels of TGF-β1 and p-Samd2/3 were signifi-cant different between group L and H. Conclusions Niaoduqing Granule can improve the quality of life and re-duce the level of serum creatinine and urea nitrogen in chronic renal failure rats received peritoneal dialysis,and the mechanism may be associated with the regulation of TGF-β1/Smad signaling pathway.