Objective To explore the effects of home-based 6-minute walk test on self-management in patients after percutaneous coronary intervention (PCI). Methods Eighty-four patients who admitted for PCI in the past five years in Cardiovascular Medicine of Zhujiang Hospital of Southern Medical University were recruited from the three major communities and were divided into intervention group and control group by random digits table method with 42 cases each. The intervention group had the home-based 6-minute walk test and monthly telephone follow-up while the control group was followed up by telephone and keep daily activities. Six months after the intervention,the changes of chronic disease self-management in-ventory were compared. Results There were significant differences the overall health self-assessment, fa-tigue,chest pain, time of aerobic exercise, the increase of self-efficacy between intervention group and control group[ (0.62±1.28) points vs. (0.20±1.71) points, (-0.84±3.27) points vs. (0.36±2.71) points, (0.04 ±3.56) points vs. (0.34 ±3.56) points, (30.47 ±123.29) min/week vs. (6.62 ±84.82) min/week, (0.42±3.01) points vs. (-0.29±2.94) points ], and there were significant differences, F=9.15, 7.42, 5.24, 3.91, 12.18, P<0.01. But there were no significant differences for other 9 aspects between two groups (P>0.05). Conclusions Home-based 6-minute walk test can be a simple self-assessment tool used at home for patients after PCI.

OBJECTIVE: To explore the pathogenesis and genetic characteristics of a fetus with a der(X)t(X;Y)(p22.3;q11.2) karyotype. METHODS: G-banding karyotyping analysis, BoBs (BACs-on-Beads) assay, and single nucleotide polymorphism array (SNP-array) were used to delineate the structural chromosomal aberration of the fetus. The parents of the fetus were also subjected to karyotyping analysis. RESULTS: The fetus and its mother were both found to have a karyotype of 46,X,add(X)(p22), while the father was normal. BoBs assay indicated that there was a lack of Xp22 but a gain of Yq11 signal. SNP-array confirmed that the fetus and its mother both had a 7.13 Mb deletion at Xp22.33p22.31 (608 021-7 736 547) and gain of a 12.52 Mb fragment at Yq11.221q11.23 (16 271 151-28 788 643). CONCLUSION The fetus was determined to have a karyotype of 46,X,der(X)t(X;Y)(p22.3;q11.2)mat. The combined use of various methods has facilitated delineation of the fetal chromosomal aberration and prediction of the risk prediction for subsequent pregnancy.
Chromosome Banding ; Chromosome Deletion ; Chromosomes, Human, X/genetics* ; Chromosomes, Human, Y/genetics* ; Female ; Fetus ; Humans ; Karyotyping ; Male ; Pregnancy ; Prenatal Diagnosis ; Translocation, Genetic