1.5 6 cases analysis of treatment for varicocele with transumbilical laparoscopic technique
Chongqing Medicine 2014;(34):4618-4619
Objective To evaluate the efficacy and safety of modified and simplified transumbilical laparoscopic technique in the treatment of varicocele.Methods Modified and simplified transumbilical laparoscopic technique was applied in the treatment of 5 6 patients with primary varicocele from July 2011 to January 2013.Then analyzing the operation time,amount of bleeding,hospitaliza-tion time and evaluating scrotal ultrasonography,semen quality and symptoms.Results All surgeries were successful,and the oper-ative time was 15-50 min,an average of(25.7±9.2)min;average amount of bleeding was less than 10 mL;hospital stays was 2~5 days,an average of(3.5±1.2)days.Patients were followed up for 3-24 months after operation.All patients′symptoms and sign significantly alleviated and semen quality in 46 patients was improved,no serious complications occurred during the follow-up peri-od.Conclusion Modified and simplified transumbilical laparoscopic technique is safe and effective in the treatment of varicocele. Moreover,it can reduce the cost of equipment and the difficulty of operation.
2.The co-infection of human papillomavirus, herpes simple virus-2 and cytomegalovirus in cervical diseases
Junjie YE ; Li MA ; Shuhua ZHAO ; Junjie LI ; Lijuan YANG
Chinese Journal of Laboratory Medicine 2013;(3):238-241
Objective To investigate infection rate of human papillomavirus as well as the correlation between cervical precancerous lesions and co-infection of human HPV,herpes simple virus-2 (HSV-2) and cytomegalovirus (CMV) in Chinese women of childbearing age in Kunming,Yunnan province.Methods A total of 2128 women (18-24,25-34,35-49 years of age),who had healthy care examination in our institute from January 2010 to March 2011,were selected prospectively in this study.The infection of HPV,HSV-2 and CMV were detected by real-time fluorescence quantitative polymerase chain reaction (FQ-PCR) and cervical precancerous lesions were determined by the ThinPrep liquid-based cytology test (TCT).Results The overall infection rates of high risk HPV (HR-HPV),HSV-2,CMV were 11.04%(235/2128),3.52% (75/2128) and 5.26% (112/2128),respectively.The HR-HPV infection rates in groups of Negative for Intraepithelial Lesion or Malignancy (NILM),Atypical Squamous Cells of Undetermined Significance (ASCUS),Low grade Squamous Intraepithelial Lesion (LSIL),High grade Squamous Intraepithelial Lesion(HSIL),and Squamous Cell Carcinoma (SCC) were 4.29% (82/1912),55.93% (66/118),84.62% (44/52),93.19% (41/44) and 2/2,respectively.HR-HPV infection rates was increased with the development of cervical lesion (r =0.644,P =0.000).No significant difference on the infection rates of HR-HPV and HSV-2 was identified between different age groups (x2 =2.979,P =0.226; x2 =0.798,P =0.671).The peak age groups for CMV infection (7.62%) were 18 to 24 years old and the infection rates of CMV decrease with age.No significant difference of HSV-2 and HR-HPV coinfection was found between the TCT-abnormal (3.24%,7/216) and control groups (2.41%,46/1912,x2 =0.557,P=0.455),and no relationship was found between HSV-2 and HR-HPV infection groups (OR =0.56,95% CI:0.17-1.82).The infection of HR-HPV were related significantly with CMV infection (OR =3.14,95% CI:1.25-7.86).Conclusion HR-HPV infection appears to be the key risk factor for cervical cancer and synergistic interaction may occur between CMV and HPV infections in the development of cervical lesion.
3.Identification of onset and offset of QRS complexes based on the characteristics of angle and amplitude.
Yang LI ; Yue HONG ; Junjie WANG
Journal of Biomedical Engineering 2014;31(3):572-576
In order to quickly and accurately identify the onset and offset of the QRS complex in electrocardiogram (ECG) signal with different forms, a triple local transform method was employed in the present study to detect the suspected onset and offset points of QRS. The accurate onset and offset points of QRS complexes were selected according to the rules drawn by the trial process based on the characteristics of angle and amplitude constituted within these suspected points. The method makes full advantage of the angle and amplitude characteristics of the QRS complex, by which the results can be acquired with some simple arithmetic quickly, accurately and adaptively. The method was investigated with data from the MIT-BIH arrhythmia database and satisfactory results were obtained.
Algorithms
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Arrhythmias, Cardiac
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diagnosis
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Databases, Factual
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Electrocardiography
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Humans
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Signal Processing, Computer-Assisted
4.Troubleshooting for Carestream GC1.5 Workstation.
Liangning YU ; Junjie ZHANG ; Zhicheng YANG
Chinese Journal of Medical Instrumentation 2015;39(6):463-466
This paper is maintenance of four kinds of failures of Carestream GC1.5 the workstation used several years to summarize, workstation software, change the host, burn, workstations transmission, and four kinds of failures of the specific case of itemized elimination steps are introduced.
Computers
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standards
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Maintenance
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Software
5.Pathogenic analysis in children with community acquired pneumonia in Jiaxing city
Suhong YANG ; Junjie FENG ; Shunfeng MAO
Chinese Pediatric Emergency Medicine 2011;18(6):508-510
Objective To study the etiology of comumunity acquired pneumonia (CAP) in children of Jiaxing city and provide the basis for the clinical diagnosis and treatment.Methods An etiological study was performed on 800 young children with CAP in Jinxing First Hospital from Jan 2008 to Dec 2010.Sputum samples were collected for isolating bacteria and checking the antigen of respiratory syncytial virus ( RSV),adenovirus ( ADV),influenza virus (IV) and parainfluenza virus ( PIV ).IgM antibodies of mycoplasma pneumoniae (MP),ADV,W and PIV paired serum samples were detected.The 202 cases with positive etiology were divided into three groups:bacteria group ( 109 cases),virus group (54 cases) and MP group (39 cases).The leukocyte,C-reactive protein (CRP) and procalcitonin (PCT) were detected.Results The etiology of CAP was identified in 202 (25.25%) children of all the 800 cases,the distribution of causal agents was as follows:Streptococcus pneumoniae in 46 cases (22.77%,46/202 ),Haemophilus influenzae in 32 cases (15.84%,32/202),Staphylococcus in 5 cases (2.48%,5/202),Klebsiella pneumoniae in 8 cases (3.96%,8/202),Escherichia coli in 12 cases (5.94%,12/202),MP in 39 cases ( 19.31%,39/202),RSV in 48 cases (23.76%,48/202),ADV in 1 case (0.50%,1/202),IV in 3 cases ( 1.49%,3/202),and PIV in 2 cases ( 0.99%,2/202 ),Streptococcus pneumoniae and RSV mixed infection in 3 cases ( 1.49%,.3/202),Streptococcus pneumoniae and MP mixed infection in 3 cases ( 1.49%,3/202).RSV infection occured mainly in infants less than 1-year-old,Streptococcus pneumoniae oceured in all ages but was mostly in 1 ~ 3years,Haemophilus influenzae infection occured mainly in infants less than 3-year-old,MP infection occured mainly in infants more than six years.The PCT levels of the three groups were (7.78 ±6.14) ng/ml,(0.39 ±0.56) ng/ml,and (0.20 ±0.34) ng/ml,respectively.There were significant differences among the three groups ( P < 0.05 ).Conclusion RSV infection occurs mainly in infants of age less than 1 year,Streptococcus pneumoniae and Haemophilus influenzae infection occur mainly in infants of age 1 ~3 years,while MP is the leading cause of pneumonia in children of age more than 6 years in Jiaxing city.We can decide pathogen on ages,clinical manifestation and PCT level to guide the rational use of drugs.
6.Effect Comparative Analysis of Sodium Hyaluronate and Chitosan in the Prevention of Thyroid Postopera-tive Adhesion
Qiang SHEN ; Quan WANG ; Junjie YANG
China Pharmacist 2014;(2):266-268
Objective:To investigate and compare the effect of sodium hyaluronate and chitosan in the prevention of thyroid post-operative adhesion. Methods:Totally 84 patients with thyroid operation in our hospital from August 2012 to August 2013 were select-ed, and according to the admission time, the patients were respectively divided into group A and B with 42 cases each. In order to pre-vent postoperative adhesion, group A was treated with sodium hyaluronate, and group B was treated with chitosan. The clinical curative effect of the two groups was compared. Results: The adhesion rate in group A was 14. 3%(6/42), which was higher than that in group B (3/42 7. 1%), while the difference was not statistically significant (P>0. 05). All the patients showed no bleeding, aller-gies and other adverse reactions, only in group A, 2 mild infection (4. 8%) occurred. The adverse reactions in the two groups were without significant difference (P>0.05). Conclusion: Sodium hyaluronate and chitosan both have the preventive effect on thyroid postoperative adhesion with similar efficiency and adverse reactions.
7.The change of T-lymphocyte subgroup in children with infectious mononucleosis
Suhong YANG ; Junjie FENG ; Aizhong MA
Chinese Pediatric Emergency Medicine 2012;19(2):166-167
Objective To investigate the change of T-lymphocyte subgroup in children with infectious mononucleosis (IM).Methods Sixty young children with IM caused by Epstein-Barr virus (EBV) were recruited for this study in Jiaxing First Hospital from Jan 2005 to Dec 2010.Thirty-six normal children were chosen as control group.Both of the two groups were detected blood test,blood smear,T-lymphocyte subgroup ( including CD3,CD4,CD8,CD4/CD8 ),liver and kidney function test,IgM antibodies of EBV,cytomegalovirus,adenovirus,and hepatitis virus.Results Compared with the control group (53.58% ± 5.97%,31.22%±8.72% ),the ratio of CD3 (81.55% ±9.04% ) and CD8(58.13% ± 13.35% ) were significantly higher in IM group( P <0.05 ).And the ratio of CD4 ( 18.19% ± 7.61% ) and CD4/CD8 (0.37 ± 0.33) were significantly lower in IM group,compared with the control group (36.98% ± 5.32%,1.98 ± 0.41 )(P < 0.05 ).While the leukocyte count,the ratio of abnormal leukomonocyte,and alanine transaminase had no correlation with the decrease of CD4/CD8 ( P > 0.05 ).Conclusion Children with IM caused by EBV have bad immunocompetence,and we can treat them with immunotherapy early.
8.Dosimetric study of permanent prostate brachytherapy utilizing 131Cs,125 I and103Pd seeds
Ruijie YANG ; Hongzhi ZHANG ; Junjie WANG
Chinese Journal of Radiation Oncology 2009;18(1):22-25
Objective To compare the dosimetric differences of permanent prostate braehytherapy utilizing 131Cs,125 I and 103 Pd seeds.Methods Twenty-five patients with T1-T2c prostate cancer who had previously implanted with 125I seeds were randomly selected in our study.The patients were re-planned with 131 Cs,125 I and 103 Pd seeds by using the Prowess Brachytherpay 3.1 planning system to the prescription doses of 115 Gy,145 Gy and 125 Gy,respectively.The seed strengths were 1.8 U,0.5 U and 1.8 U,respeetively. The prostate,prostatic urethra and anterior wall of the rectum were contoured on trans-rectal ultrasound ima ges.PTV was outlined based on the prostate volume with no margin applied.The attempted planning goals were that V100(tbe percentage volume of the prostate receiving at least 100% of the prescription doses)= 95%,D90 (the minimum percentage dose covering 90% of the prostate volume) ≥100% ,and prostatic ure thra UD10 (the maximum percentage dose receiving by 10% of the contoured urethra)≤150%.For the plan comparison,we also computed prostate V150,prostatic urethra UV120,rectum RV100,and the number of implan ted seeds and needles.The significance of the differences was tested using one way analysis of variance. Results The average V200 in the 103pd,125 I and 131 Cs plans were 28.7% ,20.9% and 19.6% (F=42.50, P =0.000) ;the average V150 were 51.9% ,42.1% and 39.4% (F=26.15,P =0.000) ;the average UV120 were 26.9% ,29.5% and 23.8% (F = 0.37,P =0.691) ; and the average rectum RV100 were 0.31 cm3, 0.22 cm3 and 0.19 cm3(F=0.43,P=0.652).For 103 Pd,124 I and 131 Cs,the average number of implanted seeds per cm3 prostate were 2.02,2.01 and 1.87(F = 1.92 ,P =0.154) ,and the average number of needles were 33.6,32.9 and 31.6(F=0.26,P=0.772). Conclusions Comparing to 124 I and 103 pd seeds used in permanent prostate brachytherapy ,131 Cs seeds has better dose homogeneity,and possible better sparing of the urethra and rectum,with comparable or less implanted seeds and needles.
9.Antibody response in mice after gastric larvae immunized with live and inactive attenuated Hepatitis A vaccine
Chen CHEN ; Junjie TANG ; Zhijun YANG
Chinese Journal of Immunology 1985;0(03):-
Objective:To survey the antibody response to live and inactive attenuated hepatitis A vaccine immunized by gastrogavage in mice.Methods:The mice were immunized by gastrogavage with live or inactive vaccine of hepatitis virus A with or without gelatin.The sera and intestinal fluid were collected after two weeks at last immunization.The specific IgG,IgA were assayed by ELISA.Results:Both of live and inactive HAV vaccine can induce the antibody response in local and system after gastrogavage immunization,the level of antibody in serum of mice is higher than that immunized by intramuscularly injection (P
10.The perfection and operation of medical quality control system.
Feng YANG ; Guanxian HE ; Junjie FAN ;
Chinese Journal of Hospital Administration 1996;0(07):-
The core of hospital management is to strengthen and upgrade medical quality and secure satisfactory medical service through the mobilization of manpower,fund and materiel.The Lanzhou Aumy Hospital has gradually perfected the medical quality control system of a general hospital in combi- nation with the hospital's management system and in consideration of the development of modern hospi- tal administration in recent years.The operational law of the system is also studied and formulated.