1.Acne Conglobata Induced by Anabolic Androgenic Steroids.
Jungyoon OHN ; Jungyoon MOON ; Seon Yong PARK ; Dae Hun SUH
Korean Journal of Dermatology 2017;55(1):71-72
No abstract available.
Acne Conglobata*
;
Acne Vulgaris*
;
Steroids*
2.Acquired Reactive Perforating Collagenosis Treated by Doxycycline: A Case Report.
Jungyoon OHN ; Yun Seon CHOE ; Je Byeong CHAE ; Kyu Han KIM
Korean Journal of Dermatology 2016;54(10):828-829
No abstract available.
Doxycycline*
3.Morgellons Disease.
Jungyoon OHN ; Seon Yong PARK ; Jungyoon MOON ; Yun Seon CHOE ; Kyu Han KIM
Annals of Dermatology 2017;29(2):223-225
Morgellons disease is a rare disease with unknown etiology. Herein, we report the first case of Morgellons disease in Korea. A 30-year-old woman presented with a 2-month history of pruritic erythematous patches and erosions on the arms, hands, and chin. She insisted that she had fiber-like materials under her skin, which she had observed through a magnifying device. We performed skin biopsy, and observed a fiber extruding from the dermal side of the specimen. Histopathological examination showed only mild lymphocytic infiltration, and failed to reveal evidence of any microorganism. The polymerase chain reaction for Borrelia burgdorferi was negative in her serum.
Adult
;
Arm
;
Asian Continental Ancestry Group
;
Biopsy
;
Borrelia burgdorferi
;
Chin
;
Female
;
Hand
;
Humans
;
Korea
;
Morgellons Disease*
;
Nerve Fibers, Myelinated
;
Polymerase Chain Reaction
;
Rare Diseases
;
Skin
4.A Case of Sebaceoma on the Right Earlobe.
Jungyoon OHN ; Seong Jin JO ; Kwang Hyun CHO
Korean Journal of Dermatology 2016;54(5):381-384
Sebaceoma, also known as sebaceous epithelioma, is a rare, benign, adnexal tumor with sebaceous differentiation. It usually appears as a yellowish papule, nodule, or plaque on the scalp and face, on which there are abundant sebaceous glands. Histologically, it is a well-circumscribed lesion composed of undifferentiated basaloid cells and mature sebaceous cells in relatively preserved lobulated architectures. A 31-year-old woman presented with a 1.3-cm ×1.1-cm nodule on the right earlobe. Mohs micrographic surgery was performed to completely remove it. Histopathological examination revealed that mature sebaceous cells with scalloped nuclei and focal cystic change were present in the lobule.
Adult
;
Carcinoma
;
Female
;
Humans
;
Mohs Surgery
;
Pectinidae
;
Scalp
;
Sebaceous Glands
5.Systemic Sarcoidosis Diagnosed through Plantar Skin Lesion in a Chronic Cough Patient.
Jungyoon OHN ; Young Woon PARK ; Dong Young KIM ; Gyeong Yul PARK ; Hyun Sun PARK ; Hyun Sun YOON ; Soyun CHO
Korean Journal of Dermatology 2015;53(7):572-573
No abstract available.
Cough*
;
Humans
;
Sarcoidosis*
;
Skin*
6.Lichen Striatus: Clinical Features and Treatment Outcomes of Topical Agent Use in 60 Pediatric Patients
Da-Ae YU ; Jungyoon OHN ; Ohsang KWON ; Kyu Han KIM
Korean Journal of Dermatology 2020;58(5):318-323
Background:
Lichen striatus (LS) is a linear, inflammatory dermatosis that mainly affects children. To date, there are limited data comparing treatment outcomes between topical agents for pediatric LS.
Objective:
To investigate the clinical features and treatment outcomes associated with the use of topical agents for pediatric LS.
Methods:
We retrospectively reviewed the medical records and clinical photographs of 60 pediatric patients classified into three groups according to the topical agent used. Treatment response was evaluated by comparing subjective symptoms and clinical photographs obtained at each visit.
Results:
A good response (>75% clinical improvement from baseline) was achieved in 55%, 46.2%, and 42.9% of patients from the calcipotriol, corticosteroid, and calcineurin inhibitor groups, respectively. There were no statistically significant differences in treatment duration among groups. However, when compared to other drugs, calcipotriol showed a trend towards shortening the disease course duration.
Conclusion
Topical use of calcipotriol, as well as corticosteroids and calcineurin inhibitors, may represent useful treatment options for pediatric LS, although further studies are required to confirm their efficacy and long-term safety.
7.Venous Leg Ulcer in a Sarcoidosis Patient: A Case Report.
Jungyoon OHN ; Sang Young BYUN ; In Su KIM ; Kyoung Chan PARK
Annals of Dermatology 2015;27(6):744-747
Venous leg ulcers, the most common form of leg ulcers, are relevant to the pathogenicity of pericapillary fibrin cuff. Sarcoidosis, a multiorgan granulomatous disease, causes fibrin deposition in tissues. We report a case of a 50-year-old man with venous leg ulcers coexisting with sarcoidosis. On the basis of the histologic findings, we propose the hypothesis that sarcoidosis patients are prone to the development of venous leg ulcers.
Capillaries
;
Fibrin
;
Humans
;
Leg Ulcer*
;
Leg*
;
Middle Aged
;
Sarcoidosis*
;
Virulence
8.Methotrexate in a Real-World Psoriasis Treatment: Is It Really a Dangerous Medication for All?.
Bo Ri KIM ; Jungyoon OHN ; Chong Won CHOI ; Sang Woong YOUN
Annals of Dermatology 2017;29(3):346-348
No abstract available.
Methotrexate*
;
Psoriasis*
9.The Advantage of Cyclosporine A and Methotrexate Rotational Therapy in Long-Term Systemic Treatment for Chronic Plaque Psoriasis in a Real World Practice.
Chong Won CHOI ; Bo Ri KIM ; Jungyoon OHN ; Sang Woong YOUN
Annals of Dermatology 2017;29(1):55-60
BACKGROUND: Psoriasis is a chronic inflammatory disease. In the treatment of psoriasis, cyclosporine is commonly prescribed systemic agents. However, long-term use of cyclosporine is not recommended because of side effects such as nephrotoxicity or hypertension. OBJECTIVE: To ascertain the improved safety of rotational therapy using cyclosporine and methotrexate, we investigated the frequency of abnormal results in laboratory test after long term rotational therapy using cyclosporine and methotrexate. METHODS: From January 2009 to June 2014, patients who were treated with cyclosporine or methotrexate were enrolled. The clinical data and usage of medications were reviewed. Laboratory tests were conducted before starting the treatment and regularly follow-up. The occurrences of any laboratory abnormalities during the treatments were investigated. RESULTS: A total of 21 psoriatic patients were enrolled. The mean of medication period and cumulative dose of cyclosporine and methotrexate were 497.81±512.06 days and 115.68±184.34 g in cyclosporine and 264.19±264.71 days and 448.71±448.63 mg in methotrexate. Laboratory abnormalities were found in total two patients after rotational therapy: two patients (9.5%) in aspartate aminotransferase/alanine aminotransferase and one patient (4.8%) in uric acid. No laboratory abnormalities were found in renal function test. CONCLUSION: We found that the rotational approaches using cyclosporine and methotrexate reduced the possibility of the development of nephrotoxicity. In addition to other advantage such as quick switching from one agent to another, the rotational therapy using cyclosporine and methotrexate can minimize the adverse events during the systemic treatment of chronic plaque psoriasis.
Aspartic Acid
;
Clinical Chemistry Tests
;
Combined Modality Therapy
;
Cyclosporine*
;
Follow-Up Studies
;
Humans
;
Hypertension
;
Methotrexate*
;
Psoriasis*
;
Uric Acid
10.The Advantage of Cyclosporine A and Methotrexate Rotational Therapy in Long-Term Systemic Treatment for Chronic Plaque Psoriasis in a Real World Practice.
Chong Won CHOI ; Bo Ri KIM ; Jungyoon OHN ; Sang Woong YOUN
Annals of Dermatology 2017;29(1):55-60
BACKGROUND: Psoriasis is a chronic inflammatory disease. In the treatment of psoriasis, cyclosporine is commonly prescribed systemic agents. However, long-term use of cyclosporine is not recommended because of side effects such as nephrotoxicity or hypertension. OBJECTIVE: To ascertain the improved safety of rotational therapy using cyclosporine and methotrexate, we investigated the frequency of abnormal results in laboratory test after long term rotational therapy using cyclosporine and methotrexate. METHODS: From January 2009 to June 2014, patients who were treated with cyclosporine or methotrexate were enrolled. The clinical data and usage of medications were reviewed. Laboratory tests were conducted before starting the treatment and regularly follow-up. The occurrences of any laboratory abnormalities during the treatments were investigated. RESULTS: A total of 21 psoriatic patients were enrolled. The mean of medication period and cumulative dose of cyclosporine and methotrexate were 497.81±512.06 days and 115.68±184.34 g in cyclosporine and 264.19±264.71 days and 448.71±448.63 mg in methotrexate. Laboratory abnormalities were found in total two patients after rotational therapy: two patients (9.5%) in aspartate aminotransferase/alanine aminotransferase and one patient (4.8%) in uric acid. No laboratory abnormalities were found in renal function test. CONCLUSION: We found that the rotational approaches using cyclosporine and methotrexate reduced the possibility of the development of nephrotoxicity. In addition to other advantage such as quick switching from one agent to another, the rotational therapy using cyclosporine and methotrexate can minimize the adverse events during the systemic treatment of chronic plaque psoriasis.
Aspartic Acid
;
Clinical Chemistry Tests
;
Combined Modality Therapy
;
Cyclosporine*
;
Follow-Up Studies
;
Humans
;
Hypertension
;
Methotrexate*
;
Psoriasis*
;
Uric Acid