Objective: This study aims to validate the Korean version of Geriatric Suicide Ideation Scale-Screen (K-GSIS-Screen) and evaluate its clinical utility for screening suicidal ideation and risk among older adults across clinical and community settings. Methods: GSIS-Screen was translated into Korean and administered to 50 community-residing older adults and 49 elderly patients attending a depression clinic in the psychiatric department of a hospital. Reliability and validity were assessed by Cron-bach’s α and exploratory factor analysis. Then, clinical utility was further examined through receiver operating characteristic(ROC) curve analysis. Results: Exploratory factor analysis confirmed a single-factor structure. Overall findings demonstrated moderate to strong in-ternal consistency, convergent validity, and discriminant validity across community and clinical settings. Additionally, K-GSISScreen differentiated between older adults with and without suicidal ideation, with those in the former group scoring higher.ROC analysis confirmed an area under curve of 0.81. Conclusion The K-GSIS-Screen appears to be a useful primary screening tool for detecting suicidal ideation among older adults. It has the potential to facilitate rapid identification of suicidal ideation in clinical and community settings, thereby sup-porting early and appropriate interventions.

Objective: This study aims to validate the Korean version of Geriatric Suicide Ideation Scale-Screen (K-GSIS-Screen) and evaluate its clinical utility for screening suicidal ideation and risk among older adults across clinical and community settings. Methods: GSIS-Screen was translated into Korean and administered to 50 community-residing older adults and 49 elderly patients attending a depression clinic in the psychiatric department of a hospital. Reliability and validity were assessed by Cron-bach’s α and exploratory factor analysis. Then, clinical utility was further examined through receiver operating characteristic(ROC) curve analysis. Results: Exploratory factor analysis confirmed a single-factor structure. Overall findings demonstrated moderate to strong in-ternal consistency, convergent validity, and discriminant validity across community and clinical settings. Additionally, K-GSISScreen differentiated between older adults with and without suicidal ideation, with those in the former group scoring higher.ROC analysis confirmed an area under curve of 0.81. Conclusion The K-GSIS-Screen appears to be a useful primary screening tool for detecting suicidal ideation among older adults. It has the potential to facilitate rapid identification of suicidal ideation in clinical and community settings, thereby sup-porting early and appropriate interventions.

Objective: This study aims to validate the Korean version of Geriatric Suicide Ideation Scale-Screen (K-GSIS-Screen) and evaluate its clinical utility for screening suicidal ideation and risk among older adults across clinical and community settings. Methods: GSIS-Screen was translated into Korean and administered to 50 community-residing older adults and 49 elderly patients attending a depression clinic in the psychiatric department of a hospital. Reliability and validity were assessed by Cron-bach’s α and exploratory factor analysis. Then, clinical utility was further examined through receiver operating characteristic(ROC) curve analysis. Results: Exploratory factor analysis confirmed a single-factor structure. Overall findings demonstrated moderate to strong in-ternal consistency, convergent validity, and discriminant validity across community and clinical settings. Additionally, K-GSISScreen differentiated between older adults with and without suicidal ideation, with those in the former group scoring higher.ROC analysis confirmed an area under curve of 0.81. Conclusion The K-GSIS-Screen appears to be a useful primary screening tool for detecting suicidal ideation among older adults. It has the potential to facilitate rapid identification of suicidal ideation in clinical and community settings, thereby sup-porting early and appropriate interventions.

Objective: This study aims to validate the Korean version of Geriatric Suicide Ideation Scale-Screen (K-GSIS-Screen) and evaluate its clinical utility for screening suicidal ideation and risk among older adults across clinical and community settings. Methods: GSIS-Screen was translated into Korean and administered to 50 community-residing older adults and 49 elderly patients attending a depression clinic in the psychiatric department of a hospital. Reliability and validity were assessed by Cron-bach’s α and exploratory factor analysis. Then, clinical utility was further examined through receiver operating characteristic(ROC) curve analysis. Results: Exploratory factor analysis confirmed a single-factor structure. Overall findings demonstrated moderate to strong in-ternal consistency, convergent validity, and discriminant validity across community and clinical settings. Additionally, K-GSISScreen differentiated between older adults with and without suicidal ideation, with those in the former group scoring higher.ROC analysis confirmed an area under curve of 0.81. Conclusion The K-GSIS-Screen appears to be a useful primary screening tool for detecting suicidal ideation among older adults. It has the potential to facilitate rapid identification of suicidal ideation in clinical and community settings, thereby sup-porting early and appropriate interventions.

PURPOSE: Single nucleotide polymorphisms (SNPs) are considered very promising genetic markers for a better understanding of the genetic basis for complex diseases. Recently, various mutations have been described in the gene encoding the androgen receptor (AR) in a variety of disease, including male pattern baldness and prostate cancer. Analyzing the SNPs among different population or races shows unpredictable different expression patterns or diseases incidences. Because the incidence and mortality of prostate cancer varies worldwide, the SNPs may explain the differences among races. It has been reported that a synonymous A/G variant in exon I of the AR (NM_000044) at position 1754 showed different expression patterns in male pattern baldness. These observations raise important questions regarding the functional and clinical significances of the AR polymorphism. First, does the A/G variation of the AR have significance in prostate cancer? Second, if not, is the variation ethnogeographically specific in Koreans? To date, no studies have given answers to the above questions. MATERIALS AND METHODS: A total 120 unrelated subjects were enrolled between May and July 2004. Of the 120 patients, 80 had pathologically confirmed prostate cancer, 20 benign prostate hyperplasia (BPH) and 20 were non-bald men. Genomic DNAs were procured from the blood of the patients. A 416bp fragment in exon I of the AR was amplified, and the polymerase chain reaction (PCR) products digested with Stu I enzyme. RESULTS: All the prostate cancer and BPH patients, and even the controls, showed the Stu I restriction enzyme site at position 1754 in the AR. CONCLUSIONS: The Stu I polymorphism in the AR is not related to the occurrence of prostate cancer in Koreans. This suggests that the high incidence of the Stu I polymorphism may be from racial differences in the AR gene. (Korean J Urol 2005;46:561-564)
Alopecia ; Continental Population Groups ; DNA ; Exons ; Genetic Markers ; Humans ; Hyperplasia ; Incidence ; Male ; Mortality ; Polymerase Chain Reaction ; Polymorphism, Single Nucleotide ; Prostate* ; Prostatic Neoplasms ; Receptors, Androgen*