1.Hidroacanthoma Simplex Clinically Mimicking Squamous Cell Carcinoma.
Jungsoo LEE ; Na Young YOON ; Seok Yong AHN ; Won Soo LEE
Korean Journal of Dermatology 2014;52(4):274-275
No abstract available.
Carcinoma, Squamous Cell*
2.Clinical Outcomes of Robot-assisted Arm Rehabilitation in Stroke Patients.
Jungsoo KIM ; Si Woon PARK ; Yongseok LEE ; Hyojin SEO
Brain & Neurorehabilitation 2015;8(1):46-52
OBJECTIVE: We conducted a retrospective data analysis to review the results of robot-assisted arm rehabilitation in post stroke patients during past 2 years and find out positive influences of the outcomes. METHOD: We measured improvements of arm function longitudinally in a group of sixty-four stroke patients, who participated in the robot-assisted arm therapy from January 2012 to December 2013. Treatment session lasted 30 to 40 minutes, 2 to 5 times a week. For at least more than one month, we used the InMotion2.0 (Interactive Motion Technologies, Watertown, MA, USA) and measured outcomes with the Fugl-Meyer assessment-upper extremity (FMA-UE), Korea-modified Barthel index (K-MBI) and InMotion robot arm evaluation index. Also, analysis on the subgroup was carried out. RESULTS: Following the robot-assisted arm rehabilitation, FMA-UE, K-MBI and InMotion robot arm evaluation index were significantly improved compared to baseline. Mean FMA-UE and K-MBI gain were 4.22 +/- 0.76, 7.63 +/- 1.18 in each. However, in the subgroup analysis, the group with less intensity treatment (640 repetition) did not show any significant improvement. CONCLUSION: This is an observational study showing improvements in arm function following robot-assisted arm rehabilitation compared to baseline, which was significant only in the subgroup who received the intervention longer and more intensity.
Arm*
;
Extremities
;
Humans
;
Observational Study
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Rehabilitation*
;
Retrospective Studies
;
Statistics as Topic
;
Stroke*
;
Upper Extremity
3.Analytical Performance of INNOVANCE Free Protein S Antigen on Sysmex CS-5100.
Sholhui PARK ; Sanghee PARK ; Jungsoo LEE ; Jungwon HUH
Laboratory Medicine Online 2019;9(1):1-5
BACKGROUND: Protein S deficiency is a common cause of thrombophilia. Free protein S has been suggested as one of the best screening tests for this deficiency. We evaluated an immunoturbidimetric free protein S reagent, INNOVANCE Free Protein S Antigen (Free PS Ag; Siemens Healthcare Diagnostics, Germany), using a CS-5100 coagulation analyzer (Sysmex, Japan). METHODS: The performance of INNOVANCE Free PS Ag was evaluated according to the CLSI guidelines. Precision, linearity, and verification of reference intervals were examined. The INNOVANCE Free PS Ag was also compared by the STA-Liatest Free Protein S immunoturbidimetric assay (Diagnostica Stago, France). RESULTS: The repeatability and within-laboratory imprecision of INNOVANCE Free PS Ag were 0.8% CV and 2.0% CV at the normal level, and 1.3% CV and 2.3% CV at the abnormally low level, respectively. This assay showed linearity from 4.0% to 151.9% (correlation coefficient r=1, P < 0.0001). Reference intervals for males and females were verified as acceptable. INNOVANCE Free PS Ag was comparable with STA-Liatest Free Protein S with a very high correlation (r=0.935, P < 0.0001). The results for the INNOVANCE antigen were higher. CONCLUSIONS: The INNOVANCE Free PS Ag on a Sysmex CS-5100 coagulation analyzer has excellent analytical performance and is comparable with the STA-Liatest Free Protein S assay.
Delivery of Health Care
;
Female
;
Humans
;
Male
;
Mass Screening
;
Protein S Deficiency
;
Protein S*
;
Thrombophilia
4.Characteristics of Atopic Dermatitis in a Post-childhood Atopic March Group.
Hemin LEE ; Jung U SHIN ; Jungsoo LEE ; Howard CHU ; Kwang Hoon LEE
Korean Journal of Dermatology 2017;55(2):110-115
BACKGROUND: Little knowledge is available on the characteristic differences between patients with atopic dermatitis (AD) with and without atopic march after childhood. OBJECTIVE: To observe and compare the phenotypes of patients with AD in regards to atopic march tendency at a single point. METHODS: We enrolled patients with AD aged between 10 and 30 years. The patients were divided into the atopic march and non-atopic march groups on the basis of an investigator-designed survey questionnaire, and their serum-specific immunoglobulin E (IgE) levels or results of the skin prick test were compared. RESULTS: In a total of 182 patients enrolled in the study, 93 patients with atopic march and 89 patients with non-atopic march were observed. When their serum-specific IgE levels or results of the skin prick test were compared between the two groups, there was no significant difference, except for a in the atopic march group. Analysis of AD severity, family history of allergic diseases, and total IgE levels between the two groups showed no statistically significant differences. CONCLUSION: Our findings suggest that although no apparent phenotype characteristics could differentiate the presence of atopic march, the history of the patient's allergic diseases should be revalidated, and clinicians should watch out for future developments of atopic march when a patient shows a high-class sensitization rate to dust mite.
Dermatitis, Atopic*
;
Dust
;
Humans
;
Immunoglobulin E
;
Immunoglobulins
;
Mites
;
Phenotype
;
Skin
5.A Case of Atypical Divided Nevus of the Penis
Jinsu LEE ; Gi-Wook LEE ; Jun-Oh SHIN ; Dongyoung ROH ; Yeona KIM ; Jungsoo LEE ; Kihyuk SHIN ; Hoonsoo KIM ; Hyunchang KO ; Byungsoo KIM ; Moon-Bum KIM ; Sang-Hyeon WON
Korean Journal of Dermatology 2024;62(10):569-571
6.A Case of Atypical Divided Nevus of the Penis
Jinsu LEE ; Gi-Wook LEE ; Jun-Oh SHIN ; Dongyoung ROH ; Yeona KIM ; Jungsoo LEE ; Kihyuk SHIN ; Hoonsoo KIM ; Hyunchang KO ; Byungsoo KIM ; Moon-Bum KIM ; Sang-Hyeon WON
Korean Journal of Dermatology 2024;62(10):569-571
7.A Case of Atypical Divided Nevus of the Penis
Jinsu LEE ; Gi-Wook LEE ; Jun-Oh SHIN ; Dongyoung ROH ; Yeona KIM ; Jungsoo LEE ; Kihyuk SHIN ; Hoonsoo KIM ; Hyunchang KO ; Byungsoo KIM ; Moon-Bum KIM ; Sang-Hyeon WON
Korean Journal of Dermatology 2024;62(10):569-571
8.A Case of Atypical Divided Nevus of the Penis
Jinsu LEE ; Gi-Wook LEE ; Jun-Oh SHIN ; Dongyoung ROH ; Yeona KIM ; Jungsoo LEE ; Kihyuk SHIN ; Hoonsoo KIM ; Hyunchang KO ; Byungsoo KIM ; Moon-Bum KIM ; Sang-Hyeon WON
Korean Journal of Dermatology 2024;62(10):569-571
9.Specific Immunotherapy in Atopic Dermatitis.
Jungsoo LEE ; Chang Ook PARK ; Kwang Hoon LEE
Allergy, Asthma & Immunology Research 2015;7(3):221-229
Allergen specific immunotherapy (SIT) using house dust mite (HDM) extracts has been performed mainly with patients of asthma and allergic rhinitis. In the meanwhile, there has been a long debate on the efficacy of SIT in atopic dermatitis (AD) with only a few double-blind placebo-controlled trials. However, several randomized controlled trials of SIT in AD revealed significant improvement of clinical symptoms and also, positive result was shown by a following meta-analysis study of these trials. In order to predict and evaluate the treatment outcome, finding a biomarker that can predict treatment responses and treatment end-points is critical but it is very challenging at the same time due to the complexity of causes and mechanisms of AD. Other considerations including standardization of the easiest and safest treatment protocol and optimizing the treatment preparations should be studied as well. This review summarizes the basics of SIT in AD including the brief mechanisms, treatment methods and schedules, and also highlights the clinical efficacy of SIT in AD along with mild, controllable adverse reactions. Immunologic effects and studies of various biomarkers are also introduced and finally, future considerations with upcoming studies on SIT were discussed.
Appointments and Schedules
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Asthma
;
Biomarkers
;
Dermatitis, Atopic*
;
Humans
;
Immunotherapy*
;
Pyroglyphidae
;
Rhinitis
;
Treatment Outcome
10.Clinical Efficacy and Safety of Naltrexone Combination Therapy in Older Patients with Severe Pruritus.
Jungsoo LEE ; Jung U SHIN ; Seongmin NOH ; Chang Ook PARK ; Kwang Hoon LEE
Annals of Dermatology 2016;28(2):159-163
BACKGROUND: Severe pruritus is a challenging condition, and it is more difficult to deal with in older patients due to their limitations in taking oral medication because of underlying diseases, possible interaction with concurrent medications, and poor general condition. OBJECTIVE: We evaluated the efficacy and safety of naltrexone (Revia®), an opioid antagonist, in elderly patients with severe pruritus that was not easily controlled with conventional antipruritics. METHODS: Eighteen patients were enrolled, with a mean age of 73 years. They additionally received 50 mg of naltrexone per day for an average of 2 months. RESULTS: Using the visual analogue scale, 13 (72.2%) of 18 patients showed a "much improved" condition, reporting more than a 50% decrease in pruritus intensity. Sixteen (88.9%) showed symptomatic improvement, and only 2 (11.1%) had persistent pruritus. Five patients reported side effects including insomnia, fatigue, constipation, and anorexia. However, reactions were either limited to the first 2 weeks or well managed. CONCLUSION: Naltrexone could be an effective and safe alternative treatment option to control severe pruritus in older patients.
Aged
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Anorexia
;
Antipruritics
;
Constipation
;
Fatigue
;
Humans
;
Naltrexone*
;
Pruritus*
;
Sleep Initiation and Maintenance Disorders