No abstract available.
Dermatitis, Atopic*

In atopic dermatitis, genetic factor undoubtedly involved, but precise mode of tra- nsmission is not yet clear. Since the true incidence and mode af transmission requires a large scale prospective study, they are very difficult to determine. This study was performed in order to elucidate incidence and hereditary backgro- und of atpoic dermatitis in the selected and secluded urban area where relatively an inbred population lived, because of substantially less immigration from other area. Investigation of this study were carried out among infants and children under 6 year old, The results were as follows 1) A total of 516 infants and children under 6 year nld were examined (male 267, female 249) 2) The incidence of atopic dermatitis was ll.2% (58/516). 3) 67. 3% of patients with atopic dermatitis (39/58) had a family history of atopic dermitis, urticaria and asthma. 4) Frequent clinical features of these patients were pruritus (93. 1%), dry or coarse skin (85. SF), and facial and extensor involvement of the skin (82.7%). 5) Molluscum contagisum (9 cases), impetigo(7 cases, strophuius (4 cases), and.. uzticaria (2 cases), were combined. with atopic dermatitis.
Asthma ; Child ; Dermatitis ; Dermatitis, Atopic* ; Emigration and Immigration ; Female ; Humans ; Incidence* ; Infant ; Pruritus ; Skin ; Urticaria

Infantile hypertrophic pyloric stenosis (IHPS) is the most common condition requiring abdominal surgery in early infancy, and is caused by hypertrophied pyloric muscle. The development of successful surgical treatment in the early 1900s by Fredet and Ramstedt made it possible for infants worldwide to survive. Modern pediatric anesthetic techniques have virtually eliminated mortality from surgical management. Atropine sulfate is a cholinergic blocking agent with potent antimuscarinic activity that decreases peristaltic contractions by relaxing smooth muscles. We treated two cases of IHPS with incomplete pyloromyotomy in 3-month-old and 5-month-old male infants by administering atropine sulfate intravenously. They were free from vomiting after 5 days of intravenous atropine sulfate treatment. In these rare cases of persistent vomiting or refractory emesis following incomplete pyloromyotomy, there may be a role for atropine sulfate.
Atropine* ; Constriction, Pathologic* ; Humans ; Infant ; Male ; Mortality ; Muscle, Smooth ; Pyloric Stenosis, Hypertrophic ; Vomiting*

This study was conducted in order to find out the attitude of housewives toward the home attendants system, the type of institute managing home attendants, the education for home attendants, the basic requisites for home attendants, and home nursing education, and identify the factors influencing on the housewives's attitude. The data were collected through questionnaires obtained from 401 housewives from March 1 to March 31, 1988. The results summarized were as follows; 1) 90.2 percent of total housewives favored the home attendants system, and housewives who had have their family member with health problem especially showed favorable response. 2) The favored types of institution managing home attendants appeared to be private social work agency(33.0%), half-private and half-public agency(32.2%), government agency(19.9%) and profit agency(2.2%). In particular, housewives who had experienced nursing favored half-private and half-public agency(37.6%). 3) As the basic requisites for home attendants, housewives wanted service attitude(37.2%), nursing education(34.4%) and nursing experience(28.4%). But, housewives with nursing experience favored nursing education rather than service attitude. 4) 91.1% of total housewives favored the home nursing education. In particular, housewives of high education level and nursing experience showed more favorable response to the home nursing education.
Education* ; Education, Nursing ; Home Nursing* ; Humans ; Nursing ; Surveys and Questionnaires ; Social Work

Chronic anteromedial rotatory instability has not been demonstrated to have a satisfactory solution and we have experienced recurrence of the instability after operations. So the authors devised a new operative technique for the TCL (Tibial collateral ligament), that is, burying of the torn end of the ligament beneath the “ㄷ” shaped bony flap. It would better be called advancement and bony reinsertion operation. And we performed modifed MacIntosh tenodesis for the torn anterior cruciate ligament. The results were as follows: l. Of six knees, four (66.6%) rated “good”, two (33.3%) “fair”, and none (O%) “poor” (follow-up period; at least 6 months). 2. The technical problem of the advancement and bony reinsertion operation was discussed.
Anterior Cruciate Ligament ; Knee ; Ligaments ; Medial Collateral Ligament, Knee ; Methods ; Recurrence ; Tenodesis

PURPOSE: The aim of the present study was to investigate the effect of single dose imipramine on nocturnal urine output in patients with nocturnal enuresis. METHODS:A total of 6 monosymptomatic enuretic patients of more than 5 years of age were enrolled in this study. We measured nocturnal urine output, urine osrnolality, creatinine clearance, osmolal clearance, excretion rate of solutes, fractional excretion of sodium and potassium, and plasma vasopressin with and without a single oral dose of imipramine(lmg/kg of body weight) at 8 p.m. RESULTS: The administration of imipramine was followed by a significant decrease in noctumal urine output(P=0.02). Urine osmolality was not significantly increased(P>0.05), but osmolal clearance was significantly decreased during imipramine medication(P=0.03). Urinary excretion rate of sodium and potassium showed a statistically insignificant trend toward lower values during imipramine administration in nocturnal enuretics. Fractional urinary excretion of sodium and potassium was significantly decreased during imipramine medication(P<0.05). There was no significant difference in plasma vasopressin level and creatinine clearance in nocturnal enuretics after imipramine. CONCLUSION: Imipramine has a vasopressin independent antidiuretic effect in patients with nocturnal enuresis. The antidiuretic effect of imipramine can be attributed prirnarily to increased a-adrenergic stimulation in the proximal tubules with secondary increased urea and water reabsorption more distally in the nephron. (J Korean Pediatr Soc 2000;43:792 - 797)
Antidiuretic Agents ; Creatinine ; Enuresis ; Humans ; Imipramine* ; Nephrons ; Nocturnal Enuresis* ; Osmolar Concentration ; Plasma ; Potassium ; Sodium ; Urea ; Vasopressins

Vitamin A is a fat-soluble, unssturated, long-chain isoprenoid an4 classic active- form found in mammalian tissue is the all-trans alcohol vitamin A (vitamin A alcohol or retinol). Vitamin A acid (VAA) represents the terminal product of vitamin A oxidation. Harris et al in 1332, first proposed the term "antikeraStinizing effect" to expression of tne effect of vitamin A on various epithelia. In 1943, Straufjord,over-enth usiastically reported tbat oral use of vitamin A also had a beneficial effect on acn . Kligman, in 1969, reported that VAA produce peeling effect and fabourable results with topically applied UAA in acne vulgaris. Many investigators reported that VAA was effective in man hyperkeratotic disorders, including psoriasis, senile comedon, verruca plana, keratosis palmaris et plantaris, plantar wart etc. Mode of actio. of VAA is unclear as yet. But, it is obserbed that continued susceptibility of skin to VAA is related to labilize lysosomes, thereby releasing prot.olytic and hydrolytic enzyme capable of inciting inflammatory reaction; VAA accelerates tum over of homey cells and converted hard keratin into soft keratin, so lessening of the coheiveness of homey cells is implied. Thus the effect of VAA in acne treatment are that VAA inhibits the formation of comedon and existing comedones tend to be extruded by the increased production of noncoherent homey cells and acceleration of the flow of cells out of the sebaceous glands. For this study, 52 patients were treated with application of topical VAA alone and 9 patients concurrently with topical VAA anl comedon extraction. The results were as follows: 1. The 43 patients treated with topical VAA alone showed significant improvement up to 70% at the end of third week. In this group, closed comedon, papules, pustules are progressively reduced during the first week but the number of open comedon transiently increased (34%) during first week of treatment, decreased after that. 2. The 9 pa.tients treated with topical VAA and co nedon extraction showed similar effect(80%) at the third week of treatment. But no sign of increase of open comedon was not shown in first week of treatment. 3. Discomfortable clinical effects such as scaling, buming, tightness were seen up to 83%, occassionally pruritus, pain edema., contact dermatitis, lichenifcation were seen.
Acceleration ; Acne Vulgaris* ; Dermatitis, Contact ; Edema ; Humans ; Keratoderma, Palmoplantar ; Lysosomes ; Pruritus ; Psoriasis ; Research Personnel ; Sebaceous Glands ; Skin ; Tretinoin ; Vitamin A ; Vitamins* ; Warts

No abstract available.
Melanoma* ; Proliferating Cell Nuclear Antigen*

No abstract available.
Breast Neoplasms* ; Breast* ; Drug Resistance, Multiple* ; Genes, MDR*

We experienced a cose of occupational asthma induced by the tobacco leaf in 49-year old man. He has worked at the Korean Tobacco and Ginseng company for 23 years but suffered from the intermittent mild wheezing and dyspnea since 6 years ago. He has not involved in the process making the tobacco directly, but just managed it at the storage barn. He showed a whole negative reaction to 55 inhalant allergens(Bencard, UK) and the allergen extracted from the yellow Korean tobacco leaf, but showed the dual asthmatic respose to the allergen bronchial provocation test with it. His basal PC is 6.35 mg/ml with methacholine inhalation challenge. Now he changed the workplace far away from the barn at the same company and is treated with bronchodilator and anti-asthmatic inhaler.
Asthma, Occupational* ; Bronchial Provocation Tests ; Dyspnea ; Humans ; Inhalation ; Methacholine Chloride ; Middle Aged ; Nebulizers and Vaporizers ; Panax ; Respiratory Sounds ; Tobacco*