1.Progression of Dermatofibrosarcoma Proruberans to Malignant Fibrous Histiocytoma: Report of a case.
Hye Rim PARK ; Eun Ha JUNG ; Jin Hee SOHN
Korean Journal of Pathology 1997;31(12):1324-1327
A 52-year-old woman was admitted with a palpable mass on the abdominal wall. This tumor had developed at the same site of a previously resected dermatofibrosarcoma protuberans. The biopsy specimen from the recurrent tumor revealed malignant fibrous histiocytoma. Immunohistochemistry with anti-CD34 antibody revealed diffuse linear positivity on the tumor cells of dermatofibrosarcoma protuberans and negativity on malignant fibrous histiocytoma. Anti CD34 antibody was valuable for a differential diagnosis of these two lesions.
Abdominal Wall
;
Biopsy
;
Dermatofibrosarcoma*
;
Diagnosis, Differential
;
Female
;
Histiocytoma, Malignant Fibrous*
;
Humans
;
Immunohistochemistry
;
Middle Aged
2.Adenoid Cystic Carcinoma of the Breast: A case report.
Eun Ha JUNG ; Hye Rim PARK ; Jin Hee SOHN
Korean Journal of Pathology 1999;33(4):299-302
Adenoid cystic carcinoma (ACC) of the breast is an uncommon carcinoma accounting for less than 1% of the breast carcinoma. This type of carcinoma has a distinctive histology, such as cylindromatous, cribriform, glandlike space and solid pattern in the variable proportion. Prognosis is favorable with rare recurrence or metastasis and the guideline for therapy is not well established. We experienced a case of ACC of right breast in the 48 year-old woman. Cytologically, it showed numerous three-dimensional, well outlined cell clusters with central core of homogeneous, eosinophilic material. The mass was well demarcated, firm and measured 2.5 2.5 2 cm. Cut surface was yellowish white and granular with focal necrosis. Histologically, the tumor was composed of cylindromatous, adenoid and solid area with marked cellular atypia. Focal invasion was identified in the adipose tissue around the tumor. Histologic and nuclear grade was III by Kleer's grade. Nodal metastasis was not found.
Adenoids*
;
Adipose Tissue
;
Breast Neoplasms
;
Breast*
;
Carcinoma, Adenoid Cystic*
;
Eosinophils
;
Female
;
Humans
;
Middle Aged
;
Necrosis
;
Neoplasm Metastasis
;
Prognosis
;
Recurrence
3.Herpes Simplex Esophagitis: A report of two cases.
Eun Ha JUNG ; Hae Kyung AHN ; Jin Hee SOHN
Korean Journal of Pathology 1999;33(4):288-291
Herpes simplex esophagitis has been recognized with increased frequency as an opportunistic infection in immunosuppressed or debilitated patients. However, it is also documented as self-limited esophagitis in apparently healthy patients. We report two cases of herpetic esophagitis diagnosed by biopsies. One case was noted in an immunocompetent patient having gastric peptic ulcer who had clinical improvement with symptomatic treatment. And the other was noted in an immunosuppressed patient having chemotherapy for gastric carcinoma who had resolution of symptoms with acyclovir therapy. Histologically, esophageal mucosa exhibited erosion and inflammatory cellular exudate with intranuclear eosinophilic inclusions in the epithelial cells. These were confirmed by the PCR and immunohistochemical stain for herpes simplex virus using a biopsy material.
Acyclovir
;
Biopsy
;
Drug Therapy
;
Eosinophils
;
Epithelial Cells
;
Esophagitis*
;
Exudates and Transudates
;
Herpes Simplex*
;
Humans
;
Mucous Membrane
;
Opportunistic Infections
;
Peptic Ulcer
;
Polymerase Chain Reaction
;
Simplexvirus
4.Clinical Experience in the Craniofacial Bone Reconstruction with Medpor(R)(Porous Polyethylene).
Dong Eun LEE ; Yong Ha KIM ; Jung Hyun SEUL
Journal of the Korean Society of Aesthetic Plastic Surgery 1998;4(1):89-98
There has been growing interest in using density porous polyethylence(Medpor) for reconstrctive facial bone surgery because of their perceived increased biocompatibility. the implant is a highly stable and somewhat flexible porous alloplast that has shown to exhibit rapid tissue ingrowth into its pores. A total of 77 Medpor implants were placed in 65 patients over a one and half year period Implants were used for orbital reconstruction, correction of craniofacial contour deformities, malar and chin area. Before operation, adequate photographic and radiologic examination was performed to carry out operation plan. Within 65 patients 38 patients were due to acute trauma, 23 patients due to posttraumatic facial deformity, and 4 patients cosmetic. the result was satisfactory: 95.4% of the patients were improved after operation. One complication occurred due to previously existed sinusitis and it was cured by conservative treatment. On the basis of our results, the Medpor implant is an excellent alternative to existing implant materials. They are easy to handle, shape, contour, position and fixate. If applied under adequate indications, the use of these implants will permit satisfactory results with little complications.
Chin
;
Congenital Abnormalities
;
Facial Bones
;
Humans
;
Orbit
;
Sinusitis
5.Effects of Resilience, Post-traumatic Stress Disorder on the Quality of Life in Patients with Breast Cancer.
Boo Young HA ; Eun Jung JUNG ; So Young CHOI
Korean Journal of Women Health Nursing 2014;20(1):83-91
PURPOSE: The purpose of this study was to identify relationships of resilience, Post-Traumatic Stress Disorder(PTSD), and quality of life of breast cancer patients. The findings from this study would provide baseline data needed for nursing intervention. METHODS: A sample of 129 breast cancer patients was recruited from three hospitals in J and C cities in Korea. The survey was conducted with participants by utilizing self-reported questionnaires. RESULTS: Quality of life showed statistically significant differences on religion (t=2.11, p=.033) and hobby (t=2.79, p=.006). Resilience and PTSD had a negative correlation (r=-.22, p=.010). Resilience and quality of life of the participants had a positive correlation (r=.58, p<.001), whereas PTSD and quality of life had a negative correlation (r=-.45, p<.001). Significant predictors of quality of life were resilience and PTSD. These variables explained 44.9% of the variance in quality of life. CONCLUSION: Findings indicate that as resilience of breast cancer patients rose higher and PTSD got lower, their quality of life increased. Based on these results, nursing interventions directed towards improving resilience and relieving PTSD is proposed.
Breast Neoplasms*
;
Breast*
;
Hobbies
;
Humans
;
Korea
;
Nursing
;
Quality of Life*
;
Surveys and Questionnaires
;
Stress Disorders, Post-Traumatic*
6.Effect of Aromatherapy Massage for the Relief of Constipation in the Elderly.
Myung Ae KIM ; Jung Kyu SAKONG ; Eun Jin KIM ; Eun Ha KIM ; Eun Ha KIM
Journal of Korean Academy of Nursing 2005;35(1):56-64
PURPOSE: The purpose of this study was to verify the effect of aromatherapy massage on constipation in the elderly. METHOD: This study for 10 day, employed a randomized control group pretest-posttest design. The experimental group received abdominal massage using essential oils with Rosemary, Lemon, and Peppermint, and the control group received a placebo massage. To evaluate the effect of aromatherapy, the degree of constipation was measured using the CAS(constipation assessment scale) and the number of bowel movements per week. Data was analyzed by repeated measures of ANOVA using the SPSS program. RESULT: The score of CAS of the experimental group was significantly lower than that of the control group. In addition the average number of bowel movements in the experimental group was higher than that of the control group. The effect of aromatherapy lasted 2 weeks after treatment, while the placebo effect lasted 7~10 days after treatment. CONCLUSION: The finding of this study showed that aromatherapy helps relieve constipation in the elderly.
Plant Oils/therapeutic use
;
Oils, Volatile/*therapeutic use
;
*Massage
;
Male
;
Humans
;
Female
;
Constipation/*therapy
;
*Aromatherapy
;
Aged, 80 and over
;
Aged
7.Diabetic Muscle Infarction in a Young Patient with Prader-Willi Syndrome and Type 2 Diabetes Mellitus
Eun-Jeong KWON ; Eun-Ji LEE ; Hak Chul JANG ; Eun Ha KANG ; Yun Jong LEE ; You-Jung HA
Journal of Korean Diabetes 2020;21(4):227-234
Diabetic muscle infarction (DMI), also known as diabetic myonecrosis, is a rare complication of diabetes mellitus (DM); hence, it is often underdiagnosed. Thus, timely diagnosis and treatment are essential for a better prognosis. We describe a 24-year-old woman with Prader-Willi syndrome and an 8-year history of uncontrolled type 2 DM, who presented with a sudden onset of fever and subacute painful swelling of her left thigh. She was finally diagnosed with DMI based on magnetic resonance imaging and muscle biopsy after excluding other infectious and inflammatory diseases of proximal muscles. The patient was treated with bed rest, strict glycemic control, and analgesics, and her symptoms gradually resolved. DMI should be considered in the differential diagnosis of patients with poorly controlled DM, who present with subacute pain and swelling of lower extremity muscles, without a history of trauma.
8.Diabetic Muscle Infarction in a Young Patient with Prader-Willi Syndrome and Type 2 Diabetes Mellitus
Eun-Jeong KWON ; Eun-Ji LEE ; Hak Chul JANG ; Eun Ha KANG ; Yun Jong LEE ; You-Jung HA
Journal of Korean Diabetes 2020;21(4):227-234
Diabetic muscle infarction (DMI), also known as diabetic myonecrosis, is a rare complication of diabetes mellitus (DM); hence, it is often underdiagnosed. Thus, timely diagnosis and treatment are essential for a better prognosis. We describe a 24-year-old woman with Prader-Willi syndrome and an 8-year history of uncontrolled type 2 DM, who presented with a sudden onset of fever and subacute painful swelling of her left thigh. She was finally diagnosed with DMI based on magnetic resonance imaging and muscle biopsy after excluding other infectious and inflammatory diseases of proximal muscles. The patient was treated with bed rest, strict glycemic control, and analgesics, and her symptoms gradually resolved. DMI should be considered in the differential diagnosis of patients with poorly controlled DM, who present with subacute pain and swelling of lower extremity muscles, without a history of trauma.
9.A case of immunologic trombocytopenic purpura in pregnancy.
Yong Eun LEE ; Seung Jin OH ; Ha Jong JANG ; Jung Sik CHO ; Huk JUNG ; Jong Il JUNG ; Sae Jun HAN
Korean Journal of Obstetrics and Gynecology 1991;34(10):1463-1469
No abstract available.
Pregnancy*
;
Purpura*
10.A Study on the Expression of p53 and nm23 Protein in the Colorectal Adenoma and Carcinoma.
Jin Hee SOHN ; Eun Ha JUNG ; Hye Rim PARK ; Young Eui PARK
Korean Journal of Pathology 1997;31(6):508-516
The expression of the nuclear phosphoprotein p53, a product of tumor suppressor gene, has been noted in a number of human tumors as a tumor suppressor. nm23 is a gene associated with low tumor metastatic potential and has been proposed to be a metastasis suppressor gene. To assess the role of p53 and nm23 expression in colorectal tumorigenesis and the association with clinicopathological parameters, an immunohistochemical study for mutant p53 and nm23 was done using mouse monoclonal antibodies in 43 colorectal carcinomas, 55 tubular adenomas and corresponding normal mucosa. In the tubular adenomas, p53 expression was significantly correlated with the degree of atypism(p<0.05) but not with other variables as well as with nm23. In the colorectal carcinoma, there were evidence of some correlation between metastasis, laterality and p53; laterality, depth of invasion and nm23 expression, but without statistical significance. Other clinicopathologic features were not significantly correlated. In the aspect of 'adenoma-carcinoma sequence', normal mucosa was totally negative for both p53 and nm23, and they were increasingly expressed through tubular adenoma to carcinoma with statistical significance(p<0.05). Therefore, it is suggested that both p53 and nm23 expressions occur in and around the time of transition to carcinoma from adenoma but are not significantly associated with the infiltrative behavior and metastasis.
Adenoma*
;
Animals
;
Antibodies, Monoclonal
;
Carcinogenesis
;
Colorectal Neoplasms
;
Genes, Tumor Suppressor
;
Genes, vif
;
Humans
;
Mice
;
Mucous Membrane
;
Neoplasm Metastasis