BACKGROUND: There has been little research done on the factors associated with snoring among adults in Korea. METHODS: Subjects for this cross-sectional study were 1940 adults aged 20 to 80 years who had visited the health promotion center at one university hospital in Chungcheongnam-do for general health check-ups. Standard interviews, anthropometrics, and biochemical studies were conducted. Habitual snoring was defined as snoring more than 4 days per week. Multiple logistic regression analysis was used to evaluate the associations between habitual snoring and age, sex, smoking, alcohol consumption, body mass index (BMI), waist circumference, hypertension, diabetes mellitus and dyslipidemia. RESULTS: The prevalence of habitual snoring was 13.9%. The proportion of problem drinkers, current smokers, BMI equal to or greater than 25 kg/m2, abdominal obesity, hypertension, diabetes mellitus, hypercholesterolemia, hypertriglyceridemia and low HDL-cholesterolemia increased significantly with increasing frequency in snoring (P<0.05). Multiple logistic regression analysis revealed that habitual snoring was independently associated with the 50-59 years age group, male, current smokers, abdominal obesity, hypertension and low HDL-cholesterolemia (P<0.05). CONCLUSIONS: These findings show that habitual snorers are at increased risk for individual risk factors associated with cardiovascular diseases. Prospective studies are needed to further examine the causal relationship between habitual snoring and cardiovascular diseases.
Adult ; Aged ; Alcohol Drinking ; Body Mass Index ; Cardiovascular Diseases ; Cross-Sectional Studies ; Diabetes Mellitus ; Health Promotion ; Humans ; Hypercholesterolemia ; Hypertension ; Hypertriglyceridemia ; Logistic Models ; Male ; Obesity, Abdominal ; Prevalence ; Risk Factors ; Smoke ; Smoking ; Snoring ; Waist Circumference

PURPOSE: The purpose of this study was to investigate the effect of parenting stress and acculturative stress on the parenting efficacy of Vietnamese married migrant women. METHODS: A total of 130 Vietnamese married immigrant women were recruited from the Multicultural Family Support Center in U-city. Data were collected using self-report questionnaires and analyzed using descriptive statistics of a t-test, one-way ANOVA, Pearson's correlation coefficient, and multiple regression analysis with the SPSS 21.0 program. RESULTS: The scores of parenting and acculturative stress level were 2.62 and 2.87, parenting efficacy level was 2.98. The Aculturative stress experience was positively correlated with parenting stress (r=0.547, p < 0.001), Parenting stress experience was negatively correlated with parenting efficacy (r=-0.486, p < 0.001), and, acculturative stress experience was negatively correlated with parenting efficacy (r=-0.460, p < 0.001). The multiple regression analysis of acculturative (t=-2.891, p=0.005) and parenting stress (t=-3.818, p < 0.001) showed a significant number of factors that explain parenting efficacy. The model included the two independent variables of acculturation stress and parenting stress which were statistically significant (F=24.966, p < 0.001), and had a descriptive result of 28.5%. CONCLUSION: The results of this study suggest the need for development and implementation of mediation measures such as substantial, cooperative, and systematic parenting programs for women in Vietnam to promote regional community support.
Acculturation ; Asian Continental Ancestry Group ; Emigrants and Immigrants ; Female ; Humans ; Negotiating ; Parenting ; Parents ; Transients and Migrants ; Vietnam

PURPOSE: This study aimed to examine the effects of subjective memory complaints, depression and cognitive function on performance of activities of daily living (ADL) in individuals with mild cognitive impairment (MCI). METHODS: A total sample consisted of 250 MCI patients diagnosed within one year. All participants were assessed with a battery of standardized neuropsychological tests, self-report measures of subjective memory complaints and depression, and performance of basic and instrumental ADL. Correlational and multiple linear regression analyses were conducted to identify the factors associated with performance of basic and instrumental ADL, respectively. RESULTS: Executive function and depression explained 9.4% of the variance in basic ADL. Reduced executive function and greater depressed mood were associated with worse performance on basic ADL. Executive function, subjective memory complaints, and time since onset of cognitive symptoms accounted for 22.2% of the variance in instrumental ADL in individuals with MCI. Lower executive function (t=−2.02, p=.044), greater memory complaints (t=5.36, p<.001), and longer periods of experiencing cognitive symptoms (t=2.24, p=.026) were associated with worse instrumental ADL performance. CONCLUSION: These results may help healthcare professionals develop interventions to improve cognitive outcomes with better understanding of the relationship among cognition, mood, and behavioral performance in individuals with MCI.
Activities of Daily Living ; Cognition ; Delivery of Health Care ; Depression ; Executive Function ; Humans ; Linear Models ; Memory Disorders ; Memory ; Mild Cognitive Impairment ; Neurobehavioral Manifestations ; Neuropsychological Tests

Intracranial vasculitis is a rare and disastrous complication of tuberculous meningitis if not treated properly. Focal neurologic deficits according to the vessels involved are common manifestation. Here, we report a 29-year-old man who suffered abrupt, bizarre behavioral changes caused by vasculitis complicating tuberculous meningoencephalitis. The diagnosis of tuberculous meningitis is based upon both the CSF findings and a chest X-ray. His systemic symptoms disappeared by after being administered antituberculous medication but various psychotic features such as hypersomnia, hyperphagia and aggressivebehavior continued. A brain MRI showed multiple small parenchymal tuberculous nodules, and the brain MR angiography revealed a narrowing of the proimal middle cerebral arteries and a reduced visualization of the cerebral vessels, suggesting widespread vasculitis. Intravenous dexamethasone successfully ameliorated his behavioral changes. In addition both the follow up brain MRI and angiography showed a normalization of the previous findings.
Adult ; Angiography ; Brain ; Dexamethasone ; Diagnosis ; Disorders of Excessive Somnolence ; Follow-Up Studies ; Humans ; Hyperphagia ; Magnetic Resonance Imaging ; Meningoencephalitis* ; Middle Cerebral Artery ; Neurologic Manifestations ; Thorax ; Tuberculosis ; Tuberculosis, Meningeal ; Vasculitis

PURPOSE: The purpose of this study is to clarify attributes, antecedents, and consequences of married immigrant women acculturation to Korean culture. METHODS: According to the procedure that Walker and Avant presented, the concept of married immigrant women's acculturation to Korea culture is analyzed. RESULTS: The defining attributes of married immigrant women acculturation to Korean culture are good communication, family and social support, mothers parenting capacity, and acceptance of mutual culture. The antecedents are interracial marriage, moving to Korea and prejudice against married immigrant women. The consequences are psychological well-being and satisfaction with family life. CONCLUSION The cultural adaptation process for the stable settlement of married women in Korean society has 4 attributes: good communication, family and social support, mothers parenting capacity, and acceptance of mutual culture. Therefore, this application will help people in the cultural adaptation process especially when they approach married women.

No abstract available.
Pregnancy* ; Purpura*

No abstract available.
Aged ; Anti-Bacterial Agents/administration & dosage ; Drainage ; Gases ; Humans ; Klebsiella pneumoniae/isolation & purification ; Liver Abscess, Pyogenic/microbiology/*radiography/therapy ; Male ; Tomography, X-Ray Computed ; Treatment Outcome

Objective: To investigate imaging biomarkers of microperfusion in contrast-induced nephropathy (CIN) using contrastenhanced ultrasound (CEUS). Materials and Methods: The CIN model was fabricated by administering indomethacin (10 mg/kg), L-NAME (15 mg/kg), and iopamidol (10 mL/kg) to Sprague-Dawley rats. After 24 hours, CEUS was performed on CIN (n = 6) and control (n = 6) rats with sulphur hexafluoride microbubbles (SonoVue). From time-intensity curves obtained from the kidney arriving time (AT), acceleration time (AC), time to peak (TTP), and peak enhancement (PE) were measured and compared between the groups. After CEUS, the rats were sacrificed, and cell apoptosis markers were evaluated to confirm the development of CIN. Results: Among CEUS parameters, AT (7.8 ± 1.6 vs. 4.2 ± 0.5 s, p = 0.002), AC (4.7 ± 1.4 vs. 2.0 ± 0.4 s, p = 0.002), and TTP (12.5 ± 2.9 vs. 6.2 ± 0.6 s, p = 0.002) were significantly prolonged in the CIN group compared to controls. PE was significantly higher in the control group than in the CIN group (17.1 ± 1.9 vs. 12.2 ± 2.0 dB, p = 0.004). In kidney tissue, mRNA and protein levels of the apoptotic makers were significantly higher in the CIN group than in the control group (p = 0.003 and p = 0.002). Conclusion CEUS parameters can be used as imaging biomarkers for microperfusion in CIN. In rats with CIN, AT, AC, and TTP were significantly prolonged, while PE was significantly lower compared to controls.

Objective: To investigate imaging biomarkers of microperfusion in contrast-induced nephropathy (CIN) using contrastenhanced ultrasound (CEUS). Materials and Methods: The CIN model was fabricated by administering indomethacin (10 mg/kg), L-NAME (15 mg/kg), and iopamidol (10 mL/kg) to Sprague-Dawley rats. After 24 hours, CEUS was performed on CIN (n = 6) and control (n = 6) rats with sulphur hexafluoride microbubbles (SonoVue). From time-intensity curves obtained from the kidney arriving time (AT), acceleration time (AC), time to peak (TTP), and peak enhancement (PE) were measured and compared between the groups. After CEUS, the rats were sacrificed, and cell apoptosis markers were evaluated to confirm the development of CIN. Results: Among CEUS parameters, AT (7.8 ± 1.6 vs. 4.2 ± 0.5 s, p = 0.002), AC (4.7 ± 1.4 vs. 2.0 ± 0.4 s, p = 0.002), and TTP (12.5 ± 2.9 vs. 6.2 ± 0.6 s, p = 0.002) were significantly prolonged in the CIN group compared to controls. PE was significantly higher in the control group than in the CIN group (17.1 ± 1.9 vs. 12.2 ± 2.0 dB, p = 0.004). In kidney tissue, mRNA and protein levels of the apoptotic makers were significantly higher in the CIN group than in the control group (p = 0.003 and p = 0.002). Conclusion CEUS parameters can be used as imaging biomarkers for microperfusion in CIN. In rats with CIN, AT, AC, and TTP were significantly prolonged, while PE was significantly lower compared to controls.

Peripheral insulin resistance in obese/type II diabetes animals results from an impairment of insulin-stimulated glucose uptake into skeletal muscle. Insulin stimulate the translocation of GLUT4 from intracellular location to the plasma membrane. Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) is implicated in mediation of fusion of GLUT4-containing vesicle with the plasma membrane. Present study investigated regulatory effects of Rhodiola sachalinensis administration and exercise training on the expression of GLUT4 protein and SNAREs protein in skeletal muscles of obese Zucker rats. Experimental animals were randomly assigned into one of five groups ; lean control (LN), obese control (OB), exercise-treated (EXE), Rhodiola sachalinensis-treated (Rho), combine of Rho & EXE (Rho-EXE). All animals of exercise training (EXE, Rho-EXE) performed treadmill running for 8 weeks, and animals of Rho groups (Rho, Rho-EXE) were dosed daily by gastric gavage during the same period. After experiment, blood were taken for analyses of glucose, insulin, and lipids levels. Mitochondrial oxidative enzyme (citrate synthase, CS ; beta-hydroxyacyl-CoA dehydrogenase, beta-HAD) activity were analysed. Skeletal muscles were dissected out for analyses of proteins (GLUT4, VAMP2, syntaxin4, SNAP23). Results are as follows. Exercise and/or Rhodiola sachalinensis administration significantly reduced body weight and improved blood lipids (TG, FFA), and increased insulin sensitivity. Endurance exercise significantly increased the activity of mitochondrial enzymes and the expression of GLUT4 protein, however, administration of Rhodiola sachalinensis did not affect them. The effect of exercise and/or Rhodiola sachalinensis administration on the expression of SNARE proteins was unclear. Our study suggested that improvement insulin sensitivity by exercise and/or Rhodiola sachalinensis administration in obese Zucker rats is independent of expression of SNARE proteins.
Animals ; Body Weight ; Cell Membrane ; Glucose Transporter Type 4 ; Glucose* ; Insulin Resistance* ; Insulin* ; Muscle, Skeletal* ; Negotiating ; Obesity ; Oxidoreductases ; Rats* ; Rats, Zucker ; Rhodiola* ; Running ; SNARE Proteins ; Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins ; Vesicle-Associated Membrane Protein 2