1.Blood Pressure Change in the Neonates during Abdominal Examination.
Young Sun KIM ; Yoon Deok KIM ; Son Moon SHIN ; Jung Hwan CHOI ; Chong Ku YUN
Journal of the Korean Pediatric Society 1987;30(11):1201-1206
No abstract available.
Blood Pressure*
;
Humans
;
Infant, Newborn*
2.Infantile Hemangioendothelioma of the Liver: Brief case report.
Hyang Jeong JO ; Ki Jung YUN ; Jae Kyu LEE ; Ji Shin LEE ; Hyung Bae MOON
Korean Journal of Pathology 1997;31(6):586-588
Infantile hemangioendothelioma of the liver is a common vascular tumor in infancy. The tumor is usually multinodular or diffuse and classified into two types. We present a case of infantile hemangioendothelioma of the liver, which predominantly consists of type 2. A 4-month-old female was admitted for an evaulation of an abdominal distension. A CT scan of the liver showed a multinodular mass. The right lobectomy was done. Grossly, the mass consisted of round nodules ranging from 2cm to 5cm in diameter. Microscopically, the tumor revealed proliferation of small vascular channels lined by endothelial cells. Bizarre cells and mitotic cells were frequently noted. Vesicular nuclei and multilayering of the endothelial cells were also noted.
Endothelial Cells
;
Female
;
Hemangioendothelioma*
;
Humans
;
Infant
;
Liver*
;
Tomography, X-Ray Computed
3.Correlation between Expression of p53 and Bcl-2 Protein and Epstein-Barr Virus Detection in Gastric Adenocarcinoma.
Ki Jung YUN ; Weon Cheol HAN ; Hyung Bae MOON ; Sang Woo JUHNG
Korean Journal of Pathology 1998;32(8):574-580
Epstein-Barr virus (EBV) has been known to be associated with a wide variety of neoplastic conditions including nasopharyngeal carcinoma, Hodgkin's disease, and non-Hodgkin's lymphoma. Recent studies reveal the presence of EBV in certain subtypes of gastric carcinoma in which EBV appears to be pathogenetically related. To evaluate the relationship between EBV and gastric adenocarcinoma, we examined EBV DNA using direct in situ polymerase chain reaction, and expression of p53 protein and bcl-2 protein using immunohistochemical staining method on paraffin embedded tissues. The materials consisted of one hundred twenty-eight gastric adenocarcinomas and twenty benign peptic ulcers. EBV DNA was detected in 14 of 128 gastric adenocarcinomas (10.9%). p53 protein was positive in 10 of 14 EBV positive adenocarcinomas (71.4%) and in 61 of 114 EBV negative adenocarcinomas (53.5%). Bcl-2 protein was positive in 2 of 14 EBV positive adenocarcinomas (14.3%) and in 19 of 114 EBV negative adenocarcinomas (16.7%). The above results indicate that EBV is associated with gastric adenocarcinoma, and p53 protein may play a role in carcinogenesis of EBV in gastric adenocarcinoma.
Adenocarcinoma*
;
Carcinogenesis
;
DNA
;
Herpesvirus 4, Human*
;
Hodgkin Disease
;
Lymphoma, Non-Hodgkin
;
Paraffin
;
Peptic Ulcer
;
Polymerase Chain Reaction
4.Primary Malignant Melanoma arising in Mucosa of the Palatine Tonsil: A case report.
Ki Jung YUN ; Hyang Jeong JO ; Hyung Bae MOON ; Sang Won YOON
Korean Journal of Pathology 1996;30(1):65-67
Maligant melanomas of the oral or nasal cavity, and the vulvovaginal area are relatively common among the melanomas of non-ocular mucosa. But, primary malignant melanoma arising in the mucosa of the palatine tonsil is rare. We present a case of primary malignant melanoma arising in the mucosa of the palatine tonsil. A 36-year-old male was admitted for evaluation of a recurrent sore throat. Tonsillectomy was performed on the basis of clinical suspicion of chronic tonsillitis. Grossly, the left tonsil was focally dark. Microscopically, the tonsillar mucosa was diffusely infiltrated with tumor cells. Tumor cells revealed numerous melanin pigments. Intraepithelial nests of tumor cells were noted, but pagetoid spread of tumor cells was not found. Tumor cells were positive for S-100 protein and HMB45 stain. There was no evidence of melanoma in the skin or eye.
Male
;
Humans
5.Malignant Neurocutaneous Melanosis: A Case Report.
Tae Young KIM ; Kwang Soo OH ; Young Jin LEE ; Ki Jung YUN ; Jong Moon KIM
Journal of Korean Neurosurgical Society 2000;29(3):389-395
No abstract available.
Melanosis*
6.Pulmonary Air Leaks in the Newborn.
Myung Chul CHO ; Beyong Il KIM ; Son Moon SHIN ; Jung Hwan CHOI ; Chong Ku YUN
Journal of the Korean Pediatric Society 1987;30(7):727-734
No abstract available.
Humans
;
Infant, Newborn*
7.The Study of Urinary Hydroxypyridinium Crosslinks Concentrations in Patients with RA or OA , and Its Clinical Significance.
Sung Kwang JUNG ; Yun Woo LEE ; Bo Moon SHIN ; Jong Won KIM
Korean Journal of Medicine 1997;53(2):232-237
OBJECTIVES: To evaluate the urinary concentrations of hydroxyridinium crosslinks of collagen in patients with osteoarthritis(OA) or rheumatoid arthritis(RA), and to compare its clinical correlation with the classic indices of the disease activity of RA. METHODS: Concentrations of urinary pyridinoline (Pyd) and deoxypyridinoline(Dpd) were measured in urinary samples collected from 18 control patients, 35 patients with OA, 45 patients with RA by competitive enzyme immunoassay using microplate coated with monoclonal antibody. RESULTS: 1) Mean urinary concentrations of Pyd in OA patients were 33.5nmol/mmol creatinine, in RA patients were 50.0nmol/mmol creatinine which were higher than the values in controls (25.1 nmol/mmol creatinine). Also, mean concentrations of Dpd in OA patients were 9.2nmol/mmol creatinine, in RA patients were 10.1nmol/mmol creatinine which were higher than the values in controls(5.6nmol/mmol creatinine)(p<0.01). 2) Mean urinary concentration of Pyd was 50.0 nmol/mmol creatinine in RA patients, which was significantly higher than the values in OA(33.5 nnmol/mmol creatinine)(p<0.05), but the mean Dpd concentratians were not significantly different between the two groups. 3) The concentrations of urinary Pyd in RA patients was significantly correlated with the biologic markers indicating inflammatory activity such as ESR(r=0.68, p<0.001), CRP(r=0.72, p<0.001) and the number of tender joint(r=0.66, p<0.01) CONCLUSION: Urinary concentrations of Pyd and Dpd were significantly higher in OA and RA patients than in controls, Especially urinary Pyd concentrations were significantly increased in RA patients than in OA patients, and strongly correlated with disease activity index of rheumatoid arthritis. The mean Dpd concentration, bone specific analogue, in RA patients was not significantly different from that of OA patients and it was not correlated with disease activity index Thus measurement of urinary Pyd might provide a sensitive, noninvasive biochemical marker for studying activity of RA.
Arthritis, Rheumatoid
;
Biomarkers
;
Collagen
;
Creatinine
;
Humans
;
Immunoenzyme Techniques
;
Osteoarthritis
8.Usefulness of Three-phasic Bone Scan in Young Male Patients Suspected of Post-traumatic Reflex Sympathetic Dystrophy Syndrome.
Won Woo LEE ; Tae Uk KIM ; Tae Hoon KIM ; Cheoul Yun JUNG ; Jin Ho MOON
Korean Journal of Nuclear Medicine 2001;35(1):52-60
PURPOSE: In young male patients who suffered several kinds of trauma with subsequent suspicious reflex sympathetic dystrophy syndrome, we performed three-phasic bone scan in order to investigate its usefulness. MATERIALS AND METHODS: Patients with narrow range of age (21-25. mean 22.8+/-1.3, all male) were included with suspicious reflex sympathetic dystrophy syndrome of 12 feet and 5 hands. Only one was bilateral feet case and 16 were ipsilateral (Rt:13, Lt:3). The etiologic traumas were 4 fractures, 4 sprains, 3 blunt trauma, 2 cellulitis, 1 tendon tear, 1 crush injury, 1 overexercise, and 1 unknown. Radiologically 3 showed osteoporotic changes. Three-phasic bone scans were performed 21.2+/-7.3wks after trauma. RESULTS: According to symptom complex, confirmatory reflex sympathetic dystrophy syndrome 4 cases and suspicious 13 were analyzed. All confirmatory cases (100%) showed increased uptake at delay phase with periarticular accentuation. Of confirmatory 4 cases, 2 showed increased uptake in all three phases (perfusion: P, blood pool: B, and delay: D), and other 2 revealed decreased P but, both increased B and D. Of suspicious 13 cases, 9(69.2%) had increased D (4 periarticular and 5 focal), 2 decreased D, and 2 symmetric D. In 12 foot cases, so-called weight bearing patterns - increased contralateral sole at P and B - were revealed in 7(58.3%). CONCLUSION: Diffuse periarticular increased uptake at delay phase of three-phasic bone scan was a compatible finding to reflex sympathetic dystrophy syndrome in young male patients whose symptom complex strongly designated post traumatic reflex sympathetic dystrophy syndrome.
Cellulitis
;
Foot
;
Hand
;
Humans
;
Male*
;
Reflex Sympathetic Dystrophy*
;
Reflex*
;
Sprains and Strains
;
Tendons
;
Weight-Bearing
9.Risk Factors for Retinopathy of Prematurity.
Beyong Il KIM ; Jung Hwan CHOI ; Chong Ku YUN ; Jae Heung LEE ; Son Moon SHIN
Journal of the Korean Pediatric Society 1987;30(10):1092-1099
No abstract available.
Retinopathy of Prematurity*
;
Risk Factors*
10.Malignant Struma Ovarii: A case report.
Ki Jung YUN ; Hyang Jeong JO ; Weon Cheol HAN ; Hyung Bae MOON
Korean Journal of Pathology 1994;28(4):436-438
Malignant struma ovarii is a rare tumor of the ovary. This can be diagnosed by histologically when carcinomas of the thyroid gland are excluded. We present a case of malignant struma ovarii arising from cystic teratoma. A 42-year-old female was admitted for evaluation of lower abdominal mass. Hysterectomy and both adnexectomy were performed on the basis of a clinical impression of uterine leiomyoma and an ovarian mass. The uterus revealed intramural leiomyoma, measuring 8 cm in diameter. Ovarian mass was predominantly cystic and partly solid. Microscopically, thyroid tissue with papillary structures were found in the solid area Papillae were complex, branching and randomly oriented. These papillae were infiltrated in the adjacent fibrous capsule, Clinical evidence of a primary thyroid carcinoma was not found.
Female
;
Humans