2.Study on the growth charateristics of in vitro cultured human epidermal cells.
Dong Chul KIM ; Young Ho LEE ; Jung Koo YOUN
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(3):390-406
No abstract available.
Humans*
3.A Case of Chronic Persistent Photosensitivity.
Jai Il YOUN ; Jin Ho JUNG ; Yoo Shin LEE
Korean Journal of Dermatology 1988;26(3):389-394
Persistent light reaction, actinic reticuloid, photosensitive eczema are three chronic photodermatoses with a feature of clinical, histological, and photobiologieal characteristics in common. These conditions were given the name of chronic persistent photosensitivity. Chronic persistent photosensitivity with the feature of photosensitive eczema developed in a 68-year-old male patient who had experienced persisited dermatitis. On phototesting the patient showed extremely severe photosensitivity to the short wave UVB. A skin biopsy showed microscopic finding of eczematous dermatitis.
Actins
;
Aged
;
Biopsy
;
Dermatitis
;
Eczema
;
Humans
;
Male
;
Radio Waves
;
Skin
4.Effect of polyadenylic.polyuridylic acid on the proliferative responsiveness of mouse thymus and spleen cells.
Bong Ki LEE ; Youn Jung YU ; Jung Koo YOUN
Yonsei Medical Journal 1990;31(2):174-181
The effects of polyadenylic.polyuridylic acid [poly(A).poly(U)] on in vitro proliferations of thymus and spleen cells from C57BL/6 mice were investigated. Mice were injected intravenously with 30 micrograms of poly(A).poly(U) or placebo. Two days later, thymus, spleen and peritoneal cells from these mice were prepared and cultured in pooled or non-pooled conditions. Cell proliferations were assessed by the technique of incorporation of tritiated thymidine. It has been revealed that the in vitro proliferations of thymus and spleen cells as well as the productions of interleukin-1 by peritoneal adhering cells and interleukin-2 by spleen cells were significantly enhanced in the cultures of cells from poly(A).poly(U)-treated mice. These enhancing effects were observed only in the cultures of pooled cells from mice whose genetic homogeneity is suspected. Furthermore, thymus cells from poly(A).poly(U)-treated mice acted as strong responder cells but not as stimulators in one way mixed cultures. Thus, the enhanced cellular responsiveness may be mediated by the increased production of cytokines and antigen recognitions of thymus-derived cells following activations via the adjuvant effect of poly(A).poly(U).
Animal
;
Cell Division/drug effects
;
Cells, Cultured
;
Female
;
Interleukin-1/biosynthesis
;
Interleukin-2/biosynthesis
;
Male
;
Mice
;
Mice, Inbred C57BL
;
Poly A-U/administration & dosage/*pharmacology
;
Spleen/*cytology
;
Support, Non-U.S. Gov't
;
Thymus Gland/*cytology
5.Intestinal Malrotation with Concurrent Portal Vein and Superior Mesenteric Vein Thromboses.
Jung Sun LEE ; In Kyu LEE ; Jungho SHIM ; Youn SI ; Yoon Suk LEE ; Seung Tack OH
Journal of the Korean Surgical Society 2010;79(Suppl 1):S37-S40
Intestinal malrotation with volvulus is generally presented as a bilious vomiting and acute intestinal obstruction in the newborn period. It could compromise vascular supply of the small bowel secondary to torsion of superior mesenteric artery (SMA) and without urgent surgical management, it could lead to detrimental outcomes such as transmural bowel infarction and sepsis. However, in chronic cases, it is rarely obstructs the vascular supply and propagates to an acute bowel infarction. Rarely, chronic malrotation with midgut volvulus may not reduce the mesenteric blood supply because of collateral vessels, and the chronically stagnated blood flow of the superior mesenteric vein (SMV) favors thrombus formation within the lumen. The recommended treatment is Ladd's procedure and anticoagulation therapy. The authors present an unusual case of intestinal malrotation with chronic volvulus resulting in superior mesenteric vein and portal vein thrombosis in a 28-year-old patient.
Adult
;
Humans
;
Infant, Newborn
;
Infarction
;
Intestinal Obstruction
;
Intestinal Volvulus
;
Mesenteric Artery, Superior
;
Mesenteric Veins
;
Portal Vein
;
Sepsis
;
Thrombosis
;
Vomiting
6.A Case of Actinic Reticuloid.
Ki Ho KIM ; Sung Moon JUNG ; Min Soo LEE ; Jung Ho YOON ; Jai Il YOUN
Annals of Dermatology 1999;11(4):240-243
Actinic reticuloid as a manifestation of chronic actinic dermatitis (CAD) is a rare dermatosis whose clinical and histologic features resemble other types of pseudolymphomas including mycosis fungoides and Jessner's lymphocytic infiltration, and it is regarded as an eventual stage of various photodermatoses like photosensitive eczema or persistent light reaction or chronic photoallergic contact dermatitis and so on. Phototests in the patients with actinic reticuloid usually reveal hypersensitivity to UVB, UVA, and sometimes to visible light. We present a case of actinic reticuloid in a 65-year-old male, whose skin lesions developed as erythematous lichenified infiltrating plaques on the face at first, and then spread themselves onto the upper trunk later. Histologically those skin lesions showed the aggregation of atypical lymphocytes and photobiologically the results of phototests revealed photosensitivity to UVB and UVA.
Actins*
;
Aged
;
Dermatitis, Photoallergic
;
Eczema
;
Humans
;
Hypersensitivity
;
Light
;
Lymphocytes
;
Male
;
Mycosis Fungoides
;
Photosensitivity Disorders
;
Pseudolymphoma
;
Skin
;
Skin Diseases
7.CT Evaluation of Nasal Cavity Masses: Differential Diagnosis between Nasal Polyps and Their Mimics.
Young Uk LEE ; Jong Dae SUH ; Eun Kyung YOUN ; Jung Hyeon KIM ; Kyeong Jae JUNG
Journal of the Korean Radiological Society 1994;31(4):633-640
PURPOSE: The purposes of this article are to identify CT findings distinguishing nasal polyps, that are the most common cause of the nasal polypiod lesions, from other nasal cavity masses and to identify differential points between benign and malignant masses of nasal cavity. MATERIALS AND METHODS: We classified 567 cases of pathologically proved nasal cavity masses into 4 different groups on CT according to the sites of origin and surrounding bone changes. RESULT: The nasal polyps were the most common cause of nasal cavity masses(515/567). Group I had a high diagnostic specificity for the nasal polyps (513/515, 99.6%) although inverted papilloma (8/522) and malignant melanoma(1/522) showed similar CT appearances. The representitive nasal mass of Group Ila was the inverted papilloma (15/24, 66.5% of the inverted papilloma). Group III pattern was seen in 3 cases of benign minor salivary gland tumor and 2 cases of pyogenic granuloma. Group IV suggested malignancy and thus was mostly observed in malignant tumors except I case of inverted papilloma and 1 case of granulomatous necrosis. CONCLUSION: The differential diagnosis between nasal polyps and the other nasal cavity masses is possible by characteristic bone changes and their sites of origin revealed on CT. In addition, it is possible to differentiate malignant masses from benign in most cases.
Diagnosis, Differential*
;
Granuloma, Pyogenic
;
Nasal Cavity*
;
Nasal Polyps*
;
Necrosis
;
Papilloma, Inverted
;
Salivary Glands, Minor
;
Sensitivity and Specificity
8.Primitive Neuroectodermal Tumor of the Ovary: A case report .
Chan Kwon JUNG ; Eun Sun JUNG ; Youn Soo LEE ; Byung Kee KIM ; Sun Moo KIM
Korean Journal of Pathology 1999;33(8):631-635
Primitive neuroectodermal tumors (PNET) of the ovary are rare tumors with an exclusive or almost exclusive malignant neuroectodermal composition, and are generally regarded as a monodermal expression of an ovarian teratoma. The tumors are basically identical with the lesions of the same name occuring typically in the central nervous system of children. These tumors consist chiefly of undifferentiated small cells resembling neuroblasts. There are also mature, well- differentiated neuroectodermal cells, such as astrocytes and ependymal cells. We report a case of ovarian PNET with glial and neuroblastic differentiation and focal teratomatous foci of non-neural tissue in a 17-year-old female.
Adolescent
;
Astrocytes
;
Central Nervous System
;
Child
;
Female
;
Humans
;
Neural Plate
;
Neuroectodermal Tumors, Primitive*
;
Ovary*
;
Teratoma
9.Congenital Pericardial Defect, A Report of Two Cases.
Young Sook LEE ; Chang Youn LEE ; Young Hwue KIM ; Jung Yun CHOI
Journal of the Korean Pediatric Society 1990;33(5):680-683
No abstract available.
10.The Application of Endoscopic Mucosectomy in Various Mucosal Lesioss of Upper Gastrointestinal Tract.
Jung Myung CHUNG ; Sang Hyuk LEE ; Youn Jae LEE ; Sang Young SEOL ; Hye Kyoung YOON
Korean Journal of Gastrointestinal Endoscopy 1996;16(3):429-434
In case of submucosal tumor, adenoma and atypism, we can't frequently use the snare polypectomy for treatment of them. Adenoma and atypism are premalignant, so other therapeutic modalities are necessary for resection of them. We have perfortned endoscopic mueosectomy such as strip biopsy, and "O"ring ligation on various mucosal lesions of upper GI tract in 23 patients(11 men, l2 women) from June 1993 to December l994. Fourteen patients wbo had adenoma were followed up endoscopically for 6 months to 24 months(mean: 14 months). The results were as follows: 23 patients(27 lesions) were enrolled in this study. Mean age was 50.3(range 32-74 years). The method of mucosectomy was strip biopsy in 19 cases(21 lesions), and "O"ring ligation in 4 cases(6 lesions). The rate of complete resection was 88.9%. If adenomas were resected incompletely, we added a laser therapy. There was no recurrence except a case in which carcinoma was detected on the other site during follow-up. No serious compication occurred such as massive bleeding or perforation. Based on the above results, the endoscopic mucosectomy is considered to be a safe and effective modality in the treatment of the flat polyps of upper GI tract and could be used for prevention of gastric cancer.
Adenoma
;
Biopsy
;
Follow-Up Studies
;
Hemorrhage
;
Humans
;
Laser Therapy
;
Ligation
;
Male
;
Polyps
;
Recurrence
;
SNARE Proteins
;
Stomach Neoplasms
;
Upper Gastrointestinal Tract*