2.Clinical Manifestation of Human Metapneumovirus Infection in Korean Children.
Jung Min AHN ; Seong Yeol CHOI ; Dong Soo KIM ; Ki Hwan KIM
Korean Journal of Pediatric Infectious Diseases 2013;20(1):28-35
PURPOSE: The aim of this study was to determine the frequency, epidemiology and the clinical manifestation of human metapneumovirus (hMPV) infection in Korean children. METHODS: From February 2010 to January 2012, we collected nasopharyngeal aspiration from 1,554 children who were hospitalized for acute lower respiratory tract infections at the Department of Pediatrics, Severance Children's Hospital. hMPV was detected by performing reverse transcriptase-polymerase chain reaction (RT-PCR). The medical records of the patients with positive results were retrospectively reviewed. RESULTS: We detected hMPV in 99 of the 1,554 hospitalized children. The mean age of the hMPV infected children was 25 months, and 87% of the illnesses occurred between April and June. The most common diagnoses were pneumonia (73%) and bronchiolitis (16%). The clinical manifestations included cough, fever, respiratory distress, hoarseness, tachypnea, and wheezing. Coinfection with other respiratory viruses was found in 43 children (43%). CONCLUSION: hMPV is one of the major virus causing acute respiratory tract infection in the age between 13 months and 48 months old with peaks during April to June. Reports of hMPV in Korea has been increasing but additional studies are required to define the epidemiology and the extent of disease caused by hMPV to determine future development of this illness in Korean children.
Bronchiolitis
;
Child
;
Child, Hospitalized
;
Coinfection
;
Cough
;
Fever
;
Hoarseness
;
Humans
;
Korea
;
Medical Records
;
Metapneumovirus
;
Pediatrics
;
Pneumonia
;
Respiratory Sounds
;
Respiratory Tract Infections
;
Retrospective Studies
;
Tachypnea
;
Viruses
3.Prevalence of Tardive Dyskinesia in Inpatients Using Antipsychotics.
Jung Yeol YOON ; Dong Yul OH ; Jong Hyuck CHOI
Korean Journal of Psychopharmacology 2004;15(3):305-311
OBJECTIVE: This study was to investigate the prevalence of tardive dyskinesia (TD) in Korean inpatients using antipsychotics and the relationship between TD and sociodemographic, clinical variables. METHODS: This study was done from January to Feburary, 2003, at the Seoul National Mental Hospital. A cross-sectional assessment of randomly selected inpatients (n=324;mean age=39.73+/-9.63years) with DSM-IV schizophrenia, schizoaffective, bipolar disorder was performed with standard rating instrument for TD and extrapyramidal symptoms. The relations between the prevalence of TD and sex, age, length of medication and dosage of antipsychotics, clozapine, and other psychotropic medication, EPS were analyzed with Chi-square test or t-test. RESULTS: Using Schooler and Kane's criteria, 20 subjects (6.17%) had TD. TD was significantly less prevalent in patients receiving clozapine. There was no other significant difference between the TD and without TD groups with respect to type of antipsychotics, other psychotropic drug, antiparkinsonian drug, mood stabilizer augmentation. CONCLUSION: The result of this study have confirmed the lower prevalence of TD among inpatients using antipsychotics compared to previous investigations. The study has also replicated the association of TD with older age. Clozapine use was associated with lower prevalence rate of TD.
Antipsychotic Agents*
;
Bipolar Disorder
;
Clozapine
;
Diagnostic and Statistical Manual of Mental Disorders
;
Hospitals, Psychiatric
;
Humans
;
Inpatients*
;
Movement Disorders*
;
Prevalence*
;
Schizophrenia
;
Seoul
4.Clinical review of adrenal tumors.
Hee Yeol BAE ; Jae Jung LEE ; Ki Chu LEE ; Chang Sig CHOI ; Soo Tong PAI
Journal of the Korean Surgical Society 1992;42(1):101-113
No abstract available.
5.Two cases of Aplastic Anemia Following Hepatitis.
Chang Yeol JEON ; Beyung Sang CHOI ; Hyeon Sook LEE ; Jung Soo KIM
Journal of the Korean Pediatric Society 1985;28(1):73-77
No abstract available.
Anemia, Aplastic*
;
Hepatitis*
6.Histologic Changes of Rabbit Skin Induced by Progressive Tissue Expansion.
Jae Ho JEONG ; Ki Yeol KIM ; See Ho CHOI ; Jung Hyun SEUL
Yeungnam University Journal of Medicine 1988;5(2):25-30
Soft-tissue expansion is a new surgical technique of providing donor tissue in modern reconstructive surgery. This technique provides a quantity of tissue of similar color, texture, and hair-bearing qualities for reconstruction of adjacent defects. It is known that the expanded skin shows several constant histologic changes including the increase in collagen fibers and vascularity within dermis, and thinning of subcutaneous tissue and dermis. In this study, the author observed serial histologic changes of rabbit skin induced by progressive tissue expansion up to excessive expansion of 6 times. The results are as follows: 1. Changes in the thickness of the epidermis was minimal until 3 times of expansion, but slight thinning was observed at excessive expansion state. 2. The thickness of the dermis was progressively decreased, and collagen fibers in the dermis was rapidly increased in early phase of expansion. 3. The vascularity in the dermis was also progressively increased. 4. The skin appendages showed no structural changes even in excessive expansion. 5. The panniculus carnosus showed no atrophic changes and the thickness was maintained in excessive expansion.
Collagen
;
Dermis
;
Epidermis
;
Humans
;
Skin*
;
Subcutaneous Tissue
;
Tissue Donors
;
Tissue Expansion*
7.Prevalence of asymptomatic hematuria, proteinemia and glucosuria in primary school children in Chonju area.
Jin Oh KIM ; Joseph CHOI ; Soo Cheol CHO ; Dae Yeol LEE ; Jung Soo KIM
Journal of the Korean Pediatric Society 1991;34(2):223-229
No abstract available.
Child*
;
Hematuria*
;
Humans
;
Jeollabuk-do*
;
Prevalence*
8.Endogenous Digoxin-like Substance in Neonatal Serum, Pregnant Women and Placental Extracts.
Heon Seob SONG ; In Soo CHOI ; Dae Yeol LEE ; Jung Soo KIM
Journal of the Korean Pediatric Society 1986;29(9):12-19
No abstract available.
Female
;
Humans
;
Placental Extracts*
;
Pregnant Women*
10.Congenital Cytomegalovirus Infection in Pregnancy: A Case Report with Sequential Fetal Brain Changes and the Latest Information on Diagnosis, Treatment and Prevention
Journal of the Korean Society of Maternal and Child Health 2021;25(2):142-151
Congenital cytomegalovirus (CMV) infection is the most common nongenetic cause of sensorineural hearing loss and a major cause of visual, intellectual, and neurodevelopmental impairment worldwide. The seroprevalence of CMV among women of childbearing age in developing countries reaches almost 100%, and the incidence of CMV infection in neonates is 1%–2%. Approximately 87% of the infected neonates are asymptomatic at birth and 13% of them have permanent sequelae. The burden of congenital malformations due to congenital CMV infection is higher than that due to Down syndrome, fetal alcohol syndrome, and spina bifida. Nevertheless, there is little knowledge regarding congenital CMV pathogenesis, diagnosis, treatment, and prevention. In this study, we report a case that showed sequential changes of fetal brain following CMV infection in pregnancy. Additionally, we reviewed the latest information on the diagnosis, treatment, and prevention of congenital CMV infection.