No abstract available.
Breast Neoplasms* ; Breast* ; Drug Resistance, Multiple* ; Genes, MDR*

No abstract available.
Child* ; Humans ; Infant, Newborn* ; Plasma* ; Renin*

No abstract available.
Gastrointestinal Neoplasms* ; Thymidine Kinase* ; Thymidine*

The widespread use of diagnostic radiography, especially using magnetic resonance imaging, has helped to increase the diagnosis of paralabral cysts in patients with chronic shoulder pain. These paralabral cysts are frequent in the anterior, the superior, and the posterior compartment of the shoulder joint but are rare in the inferior compartment. Paralabral cysts in the shoulder appear particularly in men in their third and fourth decades but rarely in elderly patients. We report a case of an inferior paralabral cyst in an elderly patient whom we treated through arthroscopic decompression.
Aged* ; Arthroscopy ; Decompression* ; Diagnosis ; Humans ; Magnetic Resonance Imaging ; Male ; Radiography ; Shoulder Joint ; Shoulder Pain ; Shoulder*

PURPOSE: To present initial and follow-up HRCT findings of lymphangitic carcinomatosis of the lung. MATERIALS AND METHODS: Both initial and follow-up HRCT scans were obtained in 18 patients with lymphangitic carcinomatosis of the lung. After dividing the patients into two groups (with anticancer chemotherapy (n=12) and without chemotherapy (n=6), changes of pulmonary parenchymal abnormalities (percentile increase or decrease in the extent of each pattern) were assessed and compared on initial and follow-up HRCTs. RESULTS: Findings on initial CT were interlobular septal thickening (n=18) (smooth in 15 and mixed smooth and nodular in three), thickening of bronchovascular bundles (n=17), areas of ground-glass opacity (n=15), polygonal lines (n=15), and nodules (n=10). With chemotherapy, the finding of polygonal lines decreased by 20/3%, while findings of ground-glass opacity, bronchovascular bundle thickening, septal thickening, and nodules remained stable. Without chemotherapy, all CT patterns of abnormalities except nodules increased by 45-88%. In three patients who did not undergo chemotherapy, smooth interlobular septal thickening changed to nodular thickening. CONCLUSION: Lymphangitic carcinomatosis of the lung manifests initially as smooth thickening of the interlobular septae, bronchovascular bundle thickening,areas of ground-glass opacity, and polygonal lines, as seen on HRCT. Without chemotherapy, the extent of CT findings increases and there is a tendency for smooth septal thickening to change to nodular thickening. Chemotherapy induces improvement or cessation of the progression of CT findings.
Carcinoma* ; Drug Therapy ; Follow-Up Studies ; Humans ; Lung*

BACKGROUNDS: Temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) is not always intractable to antiepileptic drugs (AEDs). To identify the responsiveness to AEDs and related clinical factors in TLE-HS, we performed this study. METHODS: Consecutive 100 (51 men, mean age=30.2+/-6.6, age range=19-50) patients with TLE-HS were divided into two groups by their responsiveness to AEDs. Intractable TLE-HS was defined if they had any seizures for the preceding year with at least two AEDs. Clinical factors were analyzed to find the association of the responsiveness to AEDs. RESULTS: Intractable TLE-HS was found in 68% of patients. The younger age of onset (12+/-4 vs. 31+/-8 years, p<0.0001), longer duration of epilepsy (17+/-6 vs. 2+/-1 years, p<0.0001), more than five tonic-clonic seizures (GTCs) with secondary generalization (29.4 vs. 6.3%, p=0.0009) and bilateral epileptiform abnormalities on EEG (30.9 vs 6.3%, p=0.0054) were significantly correlated with the intractable TLE-HS. According to multiple logistic regression analysis, bilateral epileptiform abnormalities on EEG (adjusted OR=9.4, 95% CI: 1.98~44.76) and more than five GTC (adjusted OR=7.7, 95% CI: 1.60~33.39) were independently related with poor responsiveness to AEDs in TLE-HS. CONCLUSIONS: The presence of hippocampal sclerosis does not necessarily mean intractability to AEDs. The clinical variables related with the poor response to ADEs in TLE-HS are more than five GTCs and bilateral epileptiform abnormalities on EEG.
Age of Onset ; Anticonvulsants ; Electroencephalography ; Epilepsy ; Epilepsy, Temporal Lobe ; Generalization (Psychology) ; Humans ; Logistic Models ; Male ; Sclerosis ; Seizures ; Temporal Lobe

Seminal vesicle cysts combined with ipsilateral renal agenesis represent a rare urologic anomaly. This urogenital malformation is explained as a developmental failure in the same mesodermal region. We report a case of seminal vesicle cyst, ipsilateral dilated ureter and renal agenesis which was treated by surgical excision. And we searched the literature to review the clinical presentation, diagnosis and treatment options of this anomaly.
Diagnosis ; Mesoderm ; Seminal Vesicles* ; Ureter*

The effects of fentanyl pretreatment on controlling the hemodynamic changes during induc- tion have been compared in 58 adult normotensive patients undergoing elective operation. Two groups of 29 patients were observed. Patients were randomly assigned to receive thiopental 5 mg/kg alone(control group) or fentanyl 8 ug/kg pretreatment with thiopental 3 mg/kg (fentanyl group) for induction of anesthesia. The changes of mean arterial pressure(MAP), heart rate(HR), peak flow index(PFI), ejection Fraction(EF), end diastolic index(EDI), cardiac indx(CI) and stroke index(SI) were checked and compared with preinduction control values. The results were compared between two groups. The results were as follows. MAP and HR 1 minute after intubation increased significantly compared with preinduction values(p<0.001) in control group but showed minimal changes in the fentanyl group. The changes of PFI, EF, EDI, CI and SI showed decreasing tendencies after 30 seconds of thiopental injection in both groups, but the changes were small in the fentanyl group. Sinus tachycardia, premature ventricu1ar contraction, bigeminy were observed in both groups but the incidences were very low in the fentanyl group. It is suggested from the above results that fentanyl pretreatment(8ug/kg) reduces the hemo- dynamic changes during induction of general anesthesia and is more safe method for induction of cardiac or cerebrovascular disease patients.
Adult ; Anesthesia ; Anesthesia, General* ; Fentanyl* ; Heart ; Hemodynamics* ; Humans ; Incidence ; Intubation ; Stroke ; Tachycardia, Sinus ; Thiopental

BACKGROUND: The major value of mammography lies in the detection of nonpalpable breast carcinomas and the mammographic appearance of clustered microcalcifications, and its predictive value in carcinomas of the breast has long been a subject of interest. Since the introduction of the fine needle localization biopsy, surgeons have performed biopsies for nonpalpable breast lesions, but there are many controversies over determining the guidelines for biopsy with only the findings of mammography. METHODS: We reviewed the correlations between the type of mammographic appearance and the histopathologic diagnosis in 74 women who had nonpalpable breast lesions that appeared only as microcalcifications on the mammograms. We subdivided the types of microcalcifications into a casting type, a crushed-stone-like type and an amorphous type. The casting type has linear and branching patterns of microcalcifications, the crushed-stone-like type has clusters of granular microcalcifications, and the amorphous type has small punctuate powdery microcalcifications arranged irregularly. RESULTS: The patients ages ranges from 25 to 82 years and 15 cases (20.3%) of breast cancer were detected among the 74 cases. Four (4) cases (28.6%) of breast carcinoma were detected in the 14 casting type cases, 8 (24.2%) in the 33 crushed-stone-like type cases, and 3 cases (11.1%) in the 27 amorphous type cases. The mean sizes of the benign and the malignant lesions were 13.11+/-11.72 mm and 12.47+/-9.46 mm, respectively, but there was no difference in size between breast carcinomas and benign lesions. CONCLUSION: We conclude that women who have microcalcifications on their mammography should undergo biopsy, especially in cases of casting type or crushed-stone-like type microcalcifications to detect breast carcinomas at an early stage.
Biopsy ; Breast Neoplasms* ; Breast* ; Diagnosis ; Female ; Humans ; Incidence* ; Mammography ; Needles

BACKGROUND: The aim of this study was to compare breast and cervical cancer screening rates between female cancer survivors and a population without cancer to identify factors related to cervical and breast cancer screening in cancer survivors. METHODS: We included 17,765 adults (738 cancer survivors and 17,027 individuals without cancer) in this study, all of whom who were 30 years of age or older and participated in the Fourth and Fifth Korean National Health and Nutritional Examination Surveys from 2007–2012. Multiple logistic regression analysis was performed to identify factors related to cervical and breast cancer screening uptake in female cancer survivors. RESULTS: The screening rate for breast cancer was 56.6%, which was higher than that in the non-cancer control group (P=0.001). The screening rate for cervical cancer was 51.4%, which was not different from that of the non-cancer control group. In terms of breast cancer screening, cancer survivors showed no significant difference in the rate of screening 5 years after their cancer diagnosis. However, cervical cancer survivors were less likely to have cervical cancer screening 10 years after their cancer diagnosis. There was no significant association between cancer screening and sociodemographic factors. CONCLUSION: Breast and cervical cancer screening rates in Korean female cancer survivors are low. Secondary primary cancer screening of female cancer survivors needs to be planned in a comprehensive manner, with the consideration of influences beyond sociodemographic factors.
Adult ; Breast Neoplasms ; Breast* ; Diagnosis ; Early Detection of Cancer ; Female* ; Humans ; Korea* ; Logistic Models ; Mass Screening* ; Nutrition Surveys* ; Survivors* ; Uterine Cervical Neoplasms*