1.Correlation of multidrug resistance gene expression with hestologic grade in locally advanced breast cancer.
Jung Won BAE ; In Sun KIM ; Jung Woong HWANG
Journal of the Korean Cancer Association 1993;25(3):376-382
No abstract available.
Breast Neoplasms*
;
Breast*
;
Drug Resistance, Multiple*
;
Genes, MDR*
2.Arthroscopic Decompression of an Inferior Paralabral Cyst of the Shoulder in an Elderly Patient: A Case Report.
Ju Oh KIM ; Ki Yong AN ; Hwang Se BONG ; Kyu Jung LEE ; Woong Bae MIN
Clinics in Shoulder and Elbow 2015;18(4):266-268
The widespread use of diagnostic radiography, especially using magnetic resonance imaging, has helped to increase the diagnosis of paralabral cysts in patients with chronic shoulder pain. These paralabral cysts are frequent in the anterior, the superior, and the posterior compartment of the shoulder joint but are rare in the inferior compartment. Paralabral cysts in the shoulder appear particularly in men in their third and fourth decades but rarely in elderly patients. We report a case of an inferior paralabral cyst in an elderly patient whom we treated through arthroscopic decompression.
Aged*
;
Arthroscopy
;
Decompression*
;
Diagnosis
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Radiography
;
Shoulder Joint
;
Shoulder Pain
;
Shoulder*
3.Changes of Plasma Inactive Renin in Newborn Infant and Children.
Pyoung Han HWANG ; Woong Kyou PARK ; Heon Sook LEE ; Jung Soo KIM ; Kyung Woo CHO
Journal of the Korean Pediatric Society 1984;27(9):872-876
No abstract available.
Child*
;
Humans
;
Infant, Newborn*
;
Plasma*
;
Renin*
4.Significance of thymidine kinase activity in the gastrointestinal cancers.
Sung Kyun ROH ; Yeon Woong CHUNG ; Jae Hwang KIM ; Soo Jung LEE ; Koing Bo KWUN
Journal of the Korean Cancer Association 1991;23(2):230-236
No abstract available.
Gastrointestinal Neoplasms*
;
Thymidine Kinase*
;
Thymidine*
5.Global Renal Cell Carcinoma Research Trends Over 30 Years: A PRISMA-Compliant Bibliometric Analysis
Jung Hoon KIM ; Ji Woong HWANG
Journal of Urologic Oncology 2024;22(1):42-51
Purpose:
Renal cell carcinoma (RCC) is a relatively common malignancy of the urinary tract. Over the past few decades, methodologies for diagnosing and managing patients with RCC have shown various developmental stages. This study was designed to provide insights into RCC research trends over that period.
Materials and Methods:
To understand RCC research trends over the past 30 years, we conducted a bibliometric analysis, an appropriate method for evaluating scholarly output. Data were acquired by searching the Web of Science for articles published between 1991 and 2020. Bibliometric analysis and VOSviewer were used to visualize and statistically analyze the research trends.
Results:
A total of 18,172 articles were identified. The most productive country was the United States (n=4,461, 26.5%), followed by China (n=3,503, 19.9%), and Japan (n=1,950, 11.9%). During keyword analysis, 3 clusters were identified, relating to gene expression, surgical outcomes, and immunotherapy. Over the last 10 years, research has mostly focused on emerging immunotherapy-related drugs.
Conclusions
Our bibliometric analysis has explained the characteristics of RCC research trends over the past 30 years.
6.Lymphangitic Carcinomatosis of the Lung: Serial Changes on High-Resolution CT.
Jae Woong HWANG ; Yookyung KIM ; Jung Hwa HWANG ; Tae Sung KIM ; Duk Woo RO ; Kyung Soo LEE
Journal of the Korean Radiological Society 1997;37(6):1051-1057
PURPOSE: To present initial and follow-up HRCT findings of lymphangitic carcinomatosis of the lung. MATERIALS AND METHODS: Both initial and follow-up HRCT scans were obtained in 18 patients with lymphangitic carcinomatosis of the lung. After dividing the patients into two groups (with anticancer chemotherapy (n=12) and without chemotherapy (n=6), changes of pulmonary parenchymal abnormalities (percentile increase or decrease in the extent of each pattern) were assessed and compared on initial and follow-up HRCTs. RESULTS: Findings on initial CT were interlobular septal thickening (n=18) (smooth in 15 and mixed smooth and nodular in three), thickening of bronchovascular bundles (n=17), areas of ground-glass opacity (n=15), polygonal lines (n=15), and nodules (n=10). With chemotherapy, the finding of polygonal lines decreased by 20/3%, while findings of ground-glass opacity, bronchovascular bundle thickening, septal thickening, and nodules remained stable. Without chemotherapy, all CT patterns of abnormalities except nodules increased by 45-88%. In three patients who did not undergo chemotherapy, smooth interlobular septal thickening changed to nodular thickening. CONCLUSION: Lymphangitic carcinomatosis of the lung manifests initially as smooth thickening of the interlobular septae, bronchovascular bundle thickening,areas of ground-glass opacity, and polygonal lines, as seen on HRCT. Without chemotherapy, the extent of CT findings increases and there is a tendency for smooth septal thickening to change to nodular thickening. Chemotherapy induces improvement or cessation of the progression of CT findings.
Carcinoma*
;
Drug Therapy
;
Follow-Up Studies
;
Humans
;
Lung*
7.The effects of polishing technique and brushing on the surface roughness of acrylic resin.
Ju Ri LEE ; Cheol Ho JEONG ; Jung Han CHOI ; Jae Woong HWANG ; Dong Hwan LEE
The Journal of Korean Academy of Prosthodontics 2010;48(4):287-293
PURPOSE: This study evaluated the effect of polishing techniques on surface roughness of polymethyl methacrylate (PMMA), as well as the influence of light-cured surface glaze and subsequent brushing on surface roughness. MATERIALS AND METHODS: A total of 60 PMMA specimens (10x10x5 mm) were made and then divided into 6 groups of 10 each according to the polymerization methods (under pressure or atmosphere) and the surface polishing methods (mechanical or chemical polishing) including 2 control groups. The mechanical polishing was performed with the carbide denture bur, rubber points and then pumice and lathe wheel. The chemical polishing was performed by applying a light-cured surface glaze (Plaquit(R); Dreve-Dentamid GmbH). Accura 2000(R), a non-contact, non-destructive, optical 3-dimensional surface analysis system, was used to measure the surface roughness (Ra) and 3-dimensional images were acquired. The surface roughness was again measured after ultrasonic tooth brushing in order to evaluate the influence of brushing on the surface roughness. The statistical analysis was performed with Mann-Whitney test and t-test using a 95% level of confidence. RESULTS: The chemically polished group showed a statistically lower mean surface roughness in comparison to the mechanically polished group (P = .0045) and the specimens polymerized under the atmospheric pressure presented a more significant difference (P = .0138). After brushing, all of the groups, except the mechanically polished group, presented rougher surfaces and showed no statistically significant differences between groups. CONCLUSION: Although the surface roughness increased after brushing, the chemical polishing technique presented an improved surface condition in comparison to the mechanical polishing technique.
Atmospheric Pressure
;
Dentures
;
Polymerization
;
Polymers
;
Polymethyl Methacrylate
;
Rubber
;
Silicates
;
Tooth
;
Ultrasonics
8.Detorque values of abutment screws in a multiple implant-supported prosthesis.
Ju Ri LEE ; Dong Hwan LEE ; Jae Woong HWANG ; Jung Han CHOI
The Journal of Korean Academy of Prosthodontics 2010;48(4):280-286
PURPOSE: This study evaluated the detorque values of screws in a multiple implant-supported superstructure using stone casts made with 2 different impression techniques. MATERIAL AND METHODS: A fully edentulous mandibular master model and a metal framework directly connected to four implants (Branemark System(R); Nobel Biocare AB) with a passive fit to each other were fabricated. Six experimental stone casts (Group 1) were made with 6 non-splinted impressions on a master cast and another 6 experimental casts (Group 2) were made with 6 acrylic resin splinted impressions. The detorque values of screws (TorqTite(R) GoldAdapt Abutment Screw; Nobel Biocare AB) were measured twice after the metal framework was fastened onto each experimental stone cast with 20 Ncm torque. Detorque values were analyzed using the mixed model with the fixed effect of screw and reading and the random effect of model for the repeated measured data at a .05 level of significance. RESULTS: The mean detorque values were 7.9 Ncm (Group 1) and 8.1 Ncm (Group 2), and the mean of minimum detorque values were 6.1 Ncm (Group 1) and 6.5 Ncm (Group 2). No statistically significant differences between 2 groups were found and no statistically significant differences among 4 screws were found for detorque values. No statistically significant differences between 2 groups were also found for minimum detorque values. CONCLUSION: In a multiple external hexagon implant-supported prosthesis, no significant differences between 2 groups were found for detorque values and for minimum detorque values. There seems to be no significant differences in screw joint stability between 2 stone cast groups made with 2 different impression techniques.
Joints
;
Prostheses and Implants
;
Splints
;
Torque
9.Development and Application of the RFID System for Patient Safety.
Eun young JUNG ; Rae Woong PARK ; Yong Su LIM ; Heejung HWANG ; Young Ho LEE ; Kug Sang JEONG ; Dong Kyun PARK
Journal of Korean Society of Medical Informatics 2009;15(4):433-444
OBJECTIVE: A system for reinforcing the patient safety has been established based on RFID (Radio Frequency Identification) technology in order to minimize a variety of potential medical errors which can take place in hospitals. The system is intended to prevent simple errors or misunderstandings attributed to manifold surgery, transfusion, and medication errors. METHODS: The RFID system was developed and established in one general hospital. The system was applied to managing the patient in the run-up to surgery during anesthesia preparation, transfusion, and anticancer medications, of which procedure information and the patient information are rechecked for assurance, respectively. RESULTS: With regard to the technological aspects, the system used 13.56 MHz of spectrum bandwidth and tags complying with ISO 15693 standard. The tag readers varied with the work, PDAs in the intensive care unit, and laptop computers in the anesthesiology department and on the general wards. After applying the system, we surveyed user's usage and satisfaction. CONCLUSION: The results of our survey indicated a high level of satisfaction with the RFID system in terms of reinforcing the patient's safety in medical environments. Respondents stated that patients were likely to wear an electronic bracelet, even if inconvenient, with their information revealed on the wrist and while going through extended medical procedures. Nurses had intentions to utilize the RFID system for managing hospital assets and tracking patients. A revitalization of the RFID system would be network stability, including the network environment, as well as quantitative effectiveness analysis.
Anesthesia
;
Anesthesiology
;
Surveys and Questionnaires
;
Electronics
;
Electrons
;
Hospitals, General
;
Humans
;
Hypogonadism
;
Intensive Care Units
;
Intention
;
Medical Errors
;
Medication Errors
;
Mitochondrial Diseases
;
Ophthalmoplegia
;
Patient Safety
;
Patients' Rooms
;
Radio Frequency Identification Device
;
Track and Field
;
Wrist
10.Clinical Factors Related With Response to Anti-epileptics in Temporal Lobe Epilepsy With Hippocampal Sclerosis.
Hyun Woo YANG ; Woong LEE ; Yong Tae JUNG ; Tae Gyu HWANG ; Sung Eun KIM
Journal of the Korean Neurological Association 2008;26(2):104-109
BACKGROUNDS: Temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) is not always intractable to antiepileptic drugs (AEDs). To identify the responsiveness to AEDs and related clinical factors in TLE-HS, we performed this study. METHODS: Consecutive 100 (51 men, mean age=30.2+/-6.6, age range=19-50) patients with TLE-HS were divided into two groups by their responsiveness to AEDs. Intractable TLE-HS was defined if they had any seizures for the preceding year with at least two AEDs. Clinical factors were analyzed to find the association of the responsiveness to AEDs. RESULTS: Intractable TLE-HS was found in 68% of patients. The younger age of onset (12+/-4 vs. 31+/-8 years, p<0.0001), longer duration of epilepsy (17+/-6 vs. 2+/-1 years, p<0.0001), more than five tonic-clonic seizures (GTCs) with secondary generalization (29.4 vs. 6.3%, p=0.0009) and bilateral epileptiform abnormalities on EEG (30.9 vs 6.3%, p=0.0054) were significantly correlated with the intractable TLE-HS. According to multiple logistic regression analysis, bilateral epileptiform abnormalities on EEG (adjusted OR=9.4, 95% CI: 1.98~44.76) and more than five GTC (adjusted OR=7.7, 95% CI: 1.60~33.39) were independently related with poor responsiveness to AEDs in TLE-HS. CONCLUSIONS: The presence of hippocampal sclerosis does not necessarily mean intractability to AEDs. The clinical variables related with the poor response to ADEs in TLE-HS are more than five GTCs and bilateral epileptiform abnormalities on EEG.
Age of Onset
;
Anticonvulsants
;
Electroencephalography
;
Epilepsy
;
Epilepsy, Temporal Lobe
;
Generalization (Psychology)
;
Humans
;
Logistic Models
;
Male
;
Sclerosis
;
Seizures
;
Temporal Lobe