1.The effects of imipramine on the lymphocyte beta-adrenergic receptor binding and plasma level of 3-methoxy-4-hydroxyphenylglycol(MHPG) in rats.
Jong Inn WOO ; Chang Yoon KIM ; Jung Hie LEE
Journal of Korean Neuropsychiatric Association 1993;32(6):1036-1048
No abstract available.
Animals
;
Imipramine*
;
Lymphocytes*
;
Plasma*
;
Rats*
2.Clinical and Obstetric Outcomes of the Teenage Pregnancy.
Yoon Hyuk LEE ; Woo Chuel JUNG ; Eu Sun RO
Korean Journal of Perinatology 2001;12(2):114-121
No abstract available.
Female
;
Pregnancy
;
Pregnancy in Adolescence*
3.Changes of intercellular adhesion molecule expression and cytogenetic abnormalities during the differentiation process in human neuroblastoma cell lines.
Jong Jae KIM ; Yoon Jung CHOI ; Chul Woo KIM
Journal of the Korean Cancer Association 1993;25(4):563-571
No abstract available.
Cell Line*
;
Chromosome Aberrations*
;
Cytogenetics*
;
Humans*
;
Neuroblastoma*
4.Experimental study of interstitial Nd:YAG laser hyperthermia on rabbit tongue mucosa.
Youn Woo NAM ; Kwang Yoon JUNG ; Jong Ouck CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):977-989
No abstract available.
Fever*
;
Mucous Membrane*
;
Tongue*
5.Surgical Treatment for 3 Cases with Established Volkmann's Ischemic Contracture of the Upper Limb
Chong Il YOO ; Jung Yoon LEE ; Jong Woo LEE
The Journal of the Korean Orthopaedic Association 1977;12(3):483-488
Volkmanns ischemic contracture, despite a relatively small incidence, is one of the most devastating complications following a limb injury. The orthopedic surgeon must be equipped to recognize and effectively treat this complication. Recently the authors have managed 3 cases with V.I.C. with the following results. 1) The etiology showed CO poisoning, arterial injury, wringer injury around the elbow in each case. 2) The method of surgical treatment depended upon deformities and functional loss of individual patient. 3) The end results seemed to be proportionate to the previous deformities and functional less. 4) Early postoperative passive exercises of the digits seemed to be helpful in restoring further range of motion.
Congenital Abnormalities
;
Elbow
;
Exercise
;
Extremities
;
Humans
;
Incidence
;
Ischemic Contracture
;
Methods
;
Orthopedics
;
Poisoning
;
Range of Motion, Articular
;
Upper Extremity
6.Adenosis Tumor of the Breast: A Case Report.
Woo Hee JUNG ; Ki Keun OH ; Pyeong Ho YOON ; Mi Kyeong JUNG ; Jung Yeon SHIM
Journal of the Korean Radiological Society 1995;32(5):831-823
Adenosis tumor is a ra re tumor of the breast and primarily consists of adenosis. Authors report a case of surgically proved adenosis tumor in a 31-year-old woman. Mammogram showed a Iobulated, well-circumscribed mass with several surrounding radiolucent halos. In the center of the mass several linear radiolucent densities were seen with the appearance of a conglomerated well-circumscribed mass such as fibroadenoma. These linear radiolucent densities were consistent with the fat between the fibrous sclerosis in pathologic specimen. Ultrasonogram showed a well-circumscribed mass with homogeneous low echogenicity, partial posterior enhancement, and bilateral acoustic shadowings.
Acoustics
;
Adult
;
Breast*
;
Female
;
Fibroadenoma
;
Humans
;
Sclerosis
;
Shadowing (Histology)
;
Ultrasonography
7.Bilateral Wilms Tumor: A Case Report.
Gyung Woo JUNG ; Jin Han YOON ; Jong Byung YOON
Korean Journal of Urology 1987;28(3):419-422
A male child of 9 months with bilateral Wilms tumor was admitted to our hospital. His chief complaint was abdominal mass. Clinical examination and IVP, USG and CT-scan disclosed bilateral Wilms tumor. Right nephrectomy and left partial nephrectomy were performed. Anuria was experienced to 24 hours and so exploratory-laparotomy was done. Renal autotranplantation was performed because of the thrombosis of renal artery. But six days after operation he died.
Anuria
;
Child
;
Humans
;
Male
;
Nephrectomy
;
Renal Artery
;
Thrombosis
;
Wilms Tumor*
8.Lead Concentrations of Pigeon's Tissue as Indicator of Lead pollution in Air and Soil.
Yung Woo BYUN ; Tae Yoon HWANG ; Jung Jeung LEE ; Chang Yoon KIM ; Jong Hak CHUNG
Korean Journal of Preventive Medicine 1996;29(1):15-26
It has been studied that a variety of fauna and flora are sensitive biological indicators which reflect the severity of regional pollution of heavy metals, but in the center of part of Taegu city the controversial issue of lead poisoning attributable to the atmosphere which contains an increased concentrations of lead has been raised recently, it is usually hard to find suitable plants or animal in the areas with heavy traffic. Pigeons are ubiquitous in and around Taegu city area, inhabiting even the most densely populated areas with heavy traffic with its small body size, high metabolic turnover, and rather limited mobility, a pigeon, as a biological indicator is expected. This study was conducted to monitor lead pollution in the Taegu and kyongju city in Korea. We measured the lead content of the various tissue of three groups of feral pigeon(Columbia livia) and soil and atmospheric lead concentration. First group was obtained io heavy traffic area in Taegu City, the second group was obtained a park in Taegu city and the third group was obtained light traffic area in kyongju city. The air and soil lead concentration of heavy traffic area in Taegu city was 0.11 microgram/m2, 4.96 microgram/g, that of park in Taegu city was 0.05 microgram/m3, 2.65 microgram/g and that of light traffic area in kyonngju city was 0.03 microgram/m3, 0.01 microgram/g. The lead content of lung, blood, kidney, femur and liver of feral pigeons in heavy traffic area in Taegu city was significantly higher than pigeons obtained in a park in Taegu city and low traffic density area in Kyonfju city(p<0.01). But stomach lead content of three group did not reflect a significant difference. In this study positive correlation was found between atmospheric lead concentrations and the concentration of lead in the pigeon's lung(r=0.5040, p<0.001), blood(r=0.3322, p<0.01), kidney(r=0.4824, p<0.001), femur(r=0.7214, p<0.001) and liverer (r=0.4836, p<0.01). we can also found positive correlation between soil lead concentrations and the concentration of lead in the pigeon's femur(r=0.4850, p<0.001), kidney(r=0.4850, p<0.001) and liver(r=0.4386, p<0.01). In the pigeon`s tissue there were significant correlations between concentration of lead in the blood and kidney(r=0.4818, p<0.001), femur(r= 0.6157, p<0.001) and liver(r=0.3889, p<0.001). In conclusion, at the heavy traffic area in Taegu city, lead concentrations found in the atmosphere and soil are reflected in the lead concentrations of different tissue of urban pigeons. It is suggested that the tissue of pigeons can be good biological indicators of environmental lead pollution.
Animals
;
Atmosphere
;
Body Size
;
Columbidae
;
Daegu
;
Femur
;
Gyeongsangbuk-do
;
Kidney
;
Korea
;
Lead Poisoning
;
Liver
;
Lung
;
Metals, Heavy
;
Soil*
;
Stomach
9.An Analysis of 94 Percutaneous Renal Biopsies.
Ho Jung KANG ; Sang Woo LIM ; Joo Yeung DO ; Kyung Woo YOON
Yeungnam University Journal of Medicine 1995;12(1):84-95
A clinical and histopathological study was performed on ninety-four patients with nephrotic syndrome (91 idiopathic and 3 secondary) who were admitted to Department of Internal Medicine, Yeungnam University Hospital during the period of nine years, from January 1985 to May 1994. The results were as following. 1. the ratio of male to female was 1.76:1. In young age group, minimal change was the most predominant type. In old age group, membranous glomerulonephritis and focal glomerulosclerosis were predominant types. 2.- The primary nephrotic syndromes were 96.8% and secondary nephrotic syndromes were 3.2%. Histopathologic findings of 94 renal biopsy tissue were classified into minimal change (43.6%) mesangial proliferative glomerulonephritis (29.8%), membranous glomerulonephritis (12.8%), Typel membranous proliferative glomerulonephritis (4.3%), focal glomerulosclerosis (3.2%) .and others (6.4%). 3. The response of eighty-six patients treated with steroid showed complete remission in 51.2%, partial remission in 20.9%, steroid dependent in 2.3%, and no effect in 25.6% of cases respectively. The response to steroid therapy was most effective in the patients with minimal change lesion. 4. In the patient with membranous proliferative glomerulonephlitis, long-term angiotensin converting enzyme inhibitor treatment showed less deterioration of renal function.
Biopsy*
;
Female
;
Glomerulonephritis
;
Glomerulonephritis, Membranous
;
Glomerulosclerosis, Focal Segmental
;
Humans
;
Internal Medicine
;
Male
;
Nephrotic Syndrome
;
Peptidyl-Dipeptidase A
10.Expression of Matrix Metalloproteinase and Tissue Inhibitor of Metallproteinase in Breast Carcinoma Related to Angiogenesis and Invasion.
Yoon Jung CHOI ; Woo Hee JUNG ; Hy De LEE ; Kwang Gil LEE
Korean Journal of Pathology 2000;34(9):652-664
Among the enzymes which are responsible for basement membrane breakdown, matrix metalloproteinases (MMP) form a family of neutral proteases that are regulated at the levels of gene transcription, proenzyme activation by the cleavage of protein, and the inhibition of the active enzyme by tissue inhibitors of matrix metalloproteinases (TIMP). Recent reports have demonstrated that the expression of these proteolytic enzymes are elevated in several solid tumors and that it can be associated with invasiveness and poor prognosis. We examined the expression of MMP-2, MMP-9, TIMP-1 and TIMP-2 by immunohistochemistry in 160 cases of infiltrating ductal carcinoma. And we compared these data with the established prognostic parameters - tumor size, nodal status, clinical stage, hormonal receptor status, microvessel density, and TGF-beta1 expression in order to evaluate how MMP and TIMP expression are associated with breast cancer progression and prognosis. Microvessel density in invasive breast carcinoma was significantly correlated with tumor size and recurrence (p<0.05). The immunohistochemical expression of TGF-beta1 was significantly associated with tumor size, lymph node metastasis, and clinical stage (p<0.05). The microvessel density was significantly correlated with TGF-beta1 expression in more than 50% of tumor cells. The immunohistochemical expression of MMP-2 and MMP-9 were significantly correlated with nodal metastasis and absence of immunoreactivity for estrogen and progesterone receptors. The immunohistochemical expression of TIMP-1 was inversely correlated with clinical stage and microvessel density while that of TIMP-2 was inversely correlated with clinical stage (p<0.05). Small size of tumor, presence of progesterone receptor, highly differentiated histologic grade, and absence of immunoreactivity for MMP-9 were significantly associated with higher survival rate, but in multivariate analysis only tumor size and MMP-9 expression appeared to affect survival independently.
Basement Membrane
;
Breast Neoplasms*
;
Breast*
;
Carcinoma, Ductal
;
Estrogens
;
Humans
;
Immunohistochemistry
;
Lymph Nodes
;
Matrix Metalloproteinases
;
Microvessels
;
Multivariate Analysis
;
Neoplasm Metastasis
;
Peptide Hydrolases
;
Prognosis
;
Receptors, Progesterone
;
Recurrence
;
Survival Rate
;
Tissue Inhibitor of Metalloproteinase-1
;
Tissue Inhibitor of Metalloproteinase-2
;
Transforming Growth Factor beta1