Coronary air embolism is a rare event. We report a case in which an acute myocardial infarction occurred in the region supplied by the right coronary artery after the removal of a double-lumen hemodialysis catheter. Emergent coronary angiography revealed air bubbles obstructing the mid-segment of the right coronary artery with slow flow phenomenon distally. The patient expired due to myocardial infarction.
Catheters* ; Coronary Angiography ; Coronary Vessels ; Embolism ; Embolism, Air* ; Humans ; Myocardial Infarction ; No-Reflow Phenomenon ; Renal Dialysis*

Laryngeal web is a rare congenital disease, and its incidence has been estimated to be 1 in 10,000 live births. A 4-year-old female child with laryngeal web was scheduled for laryngeal web removal. Smooth intubation without causing damages to the laryngeal web is important during induction. Also, it is very important to select the appropriate tube size during pediatric anesthesia. There is lack of a registered cuffed micro-laryngeal surgery (MLS) tube 3.5 mm inner diameter (ID) in Korea, and also our hospital did not have an uncuffed MLS tube 4.0 mm ID. Therefore we could not select the appropriate size of the laser tube. The patient's laryngeal web was slightly injured during intubation. We report a case of laryngeal web injury caused by intubation for laryngeal web removal and wish to state that there is lack of a registered laser tube in the size, such as a cuffed MLS tube 3.5 mm ID.
Anesthesia ; Child ; Child, Preschool ; Female ; Humans ; Incidence ; Intubation* ; Korea ; Lasers, Gas ; Live Birth

Paradoxical vocal fold movement (PVFM) is an uncommon upper airway disorder defined as paradoxical adduction of the vocal folds during inspiration. The etiology and treatment of PVFM are unclear. The physician should manage this condition because of the possibility of near complete airway obstruction in severe case of PVFM. We report a case of successful airway management in a patient with PVFM by applying continuous positive airway pressure (CPAP). In this case, PVFM was detected after removing an endotracheal tube from a 67-year-old male who underwent excision of a laryngeal mass. The patient recovered without complications in 1 day with support by CPAP.
Aged ; Airway Extubation* ; Airway Management ; Airway Obstruction ; Continuous Positive Airway Pressure* ; Humans ; Male ; Vocal Cords*

Background: As the number of large-scale studies involving multiple organizations producing data has steadily increased, an integrated system for a common interoperable format is needed. In response to the coronavirus disease 2019 (COVID-19) pandemic, a number of global efforts are underway to develop vaccines and therapeutics. We are therefore observing an explosion in the proliferation of COVID-19 data, and interoperability is highly requested in multiple institutions participating simultaneously in COVID-19 pandemic research. Results: In this study, a laboratory information management system (LIMS) approach has been adopted to systemically manage various COVID-19 non-clinical trial data, including mortality, clinical signs, body weight, body temperature, organ weights, viral titer (viral replication and viral RNA), and multiorgan histopathology, from multiple institutions based on a web interface. The main aim of the implemented system is to integrate, standardize, and organize data collected from laboratories in multiple institutes for COVID-19 non-clinical efficacy testings. Six animal biosafety level 3 institutions proved the feasibility of our system. Substantial benefits were shown by maximizing collaborative high-quality non-clinical research. Conclusions This LIMS platform can be used for future outbreaks, leading to accelerated medical product development through the systematic management of extensive data from non-clinical animal studies.