The exact etiology and pathogenesis of myopia are not known yet, although various studies of the development of myopia in experimental animals have been made. Authors attemtped whether rabbits developed axial myopia by fusing their lids at birth in one eye, or not. The monocular vision was deprived by suture of upper and lower lids in 12 rabbits which were 5 day-old. The other eye was unsutured as the control. Ten months later, we assessed refractive error, corneal curvature, axial length, and intraocular pressure and enucleation was done. We observed the histologic change of sclera with light microscope. The eyes with lid suture were more myopic(-3.35 +/- 0.99D) than the controlled eyes(-0.21 +/- 0.46D) (p<0.01). The corneal curvature and intraocular pressure were not significantly different between two groups. The axial lengths of the sutured eves were increased(21.27 +/- 1.70mm) in comparison with those of the controlled(17.39 +/- 1.83mm)(p<0.01). We conclude the difference in axial length was caused by the elongation of the posterior segment of eyeball. since lens thickness, depth of anterior chamber, and corneal curvature were identical in both groups. These were correlated with histologic change that showed thinner posterior parts of sclera of the sutured eyes than those of the controlled eyes. The results of this study demonstrate that monocular lid fusion in rabbits produced an expenmental axial myopia.
Animals ; Anterior Chamber ; Eyelids* ; Intraocular Pressure ; Myopia* ; Parturition ; Rabbits* ; Refractive Errors ; Sclera ; Sutures* ; Vision, Monocular

PURPOSE: To determine the amount of additional surgery required for patients with consecutive esotropia, who had an esodeviation angle similar to their pre-operative exodeviation angle, following bilateral lateral rectus recession surgery for intermittent exotropia. METHODS: The medical records of 29 patients who underwent surgery for intermittent exotropia from 1998 through 2013 were reviewed. These patients had consecutive esotropia with an unchanged postoperative esodeviation angle. Thirteen patients underwent esotropia surgery with the aim of full correction (Group A), while 16 patients underwent esotropia surgery with the aim of partial correction (Group B). The postoperative ocular alignment and stereopsis of both groups were compared. RESULTS: A total of 29 patients were evaluated including 13 patients in Group A and 16 patients in Group B. At the final follow-up visit, at least 24 months post procedure, Group B had a significantly greater success rate than Group A (62.5% vs. 23.1%, p = 0.039). Over-correction rates were higher in Group A than Group B (76.9% vs. 37.5%, p = 0.039). The changes during the follow-up period (6 months to their last follow-up) showed that the over-correction rate had increased from 30.8% to 76.9% in Group A (p = 0.034) and from 12.5% to 37.5% in Group B (p = 0.046). CONCLUSIONS: Consecutive esotropia surgery with the aim of partial correction showed favorable motor and sensory outcomes in patients who had a postoperative esodeviation angle similar to that of their pre-operative exodeviation. This strategy may also be helpful in preventing long-term postoperative over-correction in patients presenting with consecutive esotropia.
Depth Perception ; Esotropia ; Exotropia ; Follow-Up Studies ; Humans ; Medical Records

Fibroepithelial polyps of the ureter are usually acquired rather than congenital. Most polyps are hamartomatous growths which tend to arise in the proximal portion of the left ureter. Most patients exibit either hematuria or persistent flank pain secondary to partial ureteral obstruction. Because of false positivity of urine cytology, as well as intravenous pyelogram, the correct diagnosis is confused with malignancy. Herein we report four cases of ureteral fibroepithelial polyp, which are associated with stones resulting in partial obstruction of the ureter. One of the four cases is associated with nephrogenic adenoma in the lamina propria of the adjacent ureter. The following report describes clinicopathologic findings of fibroepithelial polyp with review of literatures.
Adenoma

To investigate the relationship between peripheral retinal degeneration and axial length, we conducted a clinical study on 254 subjectives (508 eyes) whose age lie between 19-25 years and who had no other ocular disease nor any previous eye surgery. Axial length was measured with A-scan ultrasonography and retinal periphery was inspected by 360 degrees biomicroscopic examination with Goldmann three-mirror lens. The recorded degenerative peripheral retinal lesions were; lattice degeneration, pigmentary degeneration, cystoid degeneration, white without pressure, retinal hole or tears, retinal detachment, posterior vitreous detachment. The statistical analysis was done by using the chi-square test. The mean axial length was 24.01 +/- 1.08mm with a range of 21.8 to 27.9mm. The overall prevalence of the peripheral retinal degenerations increased as axial length did. Specially, that of pigmentary, cystoid, lattice degeneration was significantly related with long axial length individually for each lesion(p<0.01). However, there was a significantly greater percentage(53.37%) of all lesions in 23.0 - 24.9mm axial length group. These results suggest that the frequency of peripheral retinal degeneration increased with axial length but there was a posibility that the peripheral retinal degenerative lesions can be found in eyes of the mean and the shorter axial length.
Prevalence ; Retinal Degeneration* ; Retinal Perforations ; Retinaldehyde* ; Ultrasonography ; Vitreous Detachment

PURPOSE: This study is to determine actor and partner effects of stress coping on quality of life (QoL) of cancer patients and their primary caregivers using an actor-partner independence model (APIM). METHODS: The subjects of this study were adults aged 19 years and over who visited a hospital. They were diagnosed with cancer and were treated with chemotherapy, radiotherapy, and hematopoietic stem cell transplantation. 137 patients with cancer and 137 caregivers were included in the study. RESULTS: Cancer patient stress had a direct effect on their stress coping (β=.42, p=.004). Primary caregiver stress also had a direct effect on their stress coping (β=.41, p < .001). Factors significantly affecting cancer patients' QoL were patient stress (β=−.14, p=.002), stress coping (β=.24, p < .001), and primary caregiver stress coping (β=.11, p=.021). Factors significantly affecting primary caregiver QoL were primary caregiver stress (β=−.22, p < .001) and their stress coping (β=.14, p=.009). CONCLUSION: In order to improve the quality of life of cancer patients and caregivers, it is necessary to consider cancer patients and caregivers as a unit when constructing intervention programs for stress management.
Adult ; Caregivers* ; Drug Therapy ; Hematopoietic Stem Cell Transplantation ; Humans ; Quality of Life* ; Radiotherapy

It has been reported that risperidone, an atypical antipsychotic drug, is less likely to induce neurologic side effects than conventional antipsychotics. However, long-term administration of risperidone has been reported to produce severe irreversible neurologic side effects, such as tardive dyskinesia. Tardive dystonia has been suggested as a distinct movement disorder different from tardive dyskinesia and a few cases of risperidone-induced tardive dystonia were reported recently. We experienced two cases of tardive dystonia, which developed in association with the long-term administration of risperidone, and the symptoms of tardive dystonia were slightly subsided after discontinuation of risperidone. It is necessary to be cautious of dystonic symptoms during long-term administration of risperidone.
Antipsychotic Agents ; Movement Disorders* ; Risperidone

PURPOSE: To evaluate the central corneal thickness (CCT) and corneal endothelial cell density (ENDO) in pseudoexfoliation syndrome. METHODS: Medical records of patients who underwent a preoperative examination for cataract surgery and an examination for glaucoma were retrospectively reviewed. The present study included 44 patients (59 eyes) and age- and sex-matched controls. The total pseudoexfoliation patients divided into 2 groups, such as pseudoexfoliation syndrome (28 eyes) and pseudoexfoliative glaucoma (21 eyes) .The intraocular pressure (IOP), CCT, ENDO, corneal curvature (CC) and axial length (AL) were measured. RESULTS: The total pseudoexfoliation group showed significantly higher IOP (p = 0.001), thinner CCT (p = 0.003) and lower ENDO (p = 0.037). The pseudoexfoliation syndrome group showed significantly thinner CCT (p = 0.010) and lower EDNO (p = 0.041), but no significant difference in IOP (p = 0.941). There was no significant difference in CCT (p = 0.060) and ENDO (p = 0.171) between the pseudoexfoliative glaucoma group and controls, but the pseudoexfolliative glaucoma group showed significantly higher IOP (p < 0.001). CONCLUSIONS: The pseudoexfoliation group showed thinner CCT which should be taken into consideration when evaluating IOP with the applanation tonometer and diagnosing glaucoma, especially in pseudoexfoliation syndrome patients.
Cataract ; Endothelial Cells ; Exfoliation Syndrome ; Glaucoma ; Humans ; Intraocular Pressure ; Medical Records ; Retrospective Studies

Title change to "Factors Relating with the Resolution of Primary Vesicoureteral Reflux in Infants with Urinary Tract Infection"

BACKGROUND/AIMS: Stones remaining after endoscopic treatment of common bile duct (CBD) stones may evolve into recurrent CBD stones or serve as nuclei for the growth of new CBD stones. The aim of the present study was to identify risk factors for the presence of residual stones after endoscopic treatment of CBD stones. METHODS: We performed a retrospective case-control study; 55 patients with residual stones were enrolled as the case group and 281 patients without such stones served as a control group. We collected information on age, sex, stone characteristics, laboratory findings, the presence/absence of a periampullary diverticulum, use of mechanical lithotripsy, use of (single-procedure) endoscopic papillary balloon dilatation (EPBD), presence/absence of multiple CBD stones, CBD stone size, CBD stone diameter, whether CBDs were associated with gall bladder stones, and histories of prior cholecystectomy and cholecystectomy performed after endoscopic treatment. RESULTS: Upon univariate analysis, mechanical lithotripsy, single-procedure EPBD, the presence of multiple CBD stones (more than four), and CBD stone diameter greater than 1 cm were risk factors for the presence of residual stones. Upon multivariate analysis, single-procedure EPBD (odds ratio [OR], 3.174; 95% confidence interval [CI], 1.68-6.00; p = 0.000), and more than four CBD stones (OR, 2.459; 95% CI, 1.24-4.86; p = 0.010), were significant risk factors for the presence of residual stones. CONCLUSIONS: Single-procedure EPBD and the presence of more than four CBD stones were independent risk factors for the presence of residual stones. Particular care, featuring meticulous inspection, is necessary when treating patients with these risk factors. A second procedure, endoscopic retrograde cholangiopancreatography, may be required.
Bile Ducts* ; Case-Control Studies ; Cholangiopancreatography, Endoscopic Retrograde ; Cholecystectomy ; Common Bile Duct* ; Dilatation ; Diverticulum ; Gallstones ; Humans ; Lithotripsy ; Multivariate Analysis ; Retrospective Studies ; Risk Factors* ; Urinary Bladder Calculi