1.Serum Levels of ICAM-1(In tercelluar Adhesion Molecule-1) in Invasive Cervical Cancer.
Yong Min KIM ; Yoon Jung CHO ; Kyu Wan LEE
Korean Journal of Gynecologic Oncology and Colposcopy 1999;10(3):258-263
ICAM-l(Intercellular adhesion molecule-1) is an important early marker of immune activation and response. ICAM-1 is expressed on varous cell types and observed in a variety of diseases, including patients with asthma, melanoma, prostatic cancer, ovarian and colon cancer. Some authors demonstrated the expression of ICAM-1 protein in high-grade intraepithelial squamous neoplasia of cervix by immunohistochemistry and suggested that the expression was related to human papillomavirus infection. The aim of this study was to determine the serum levels of soluble intercellular adhesion molecule-1(sICAM-1) in patients with squamous cell carcinoma of the cervix, Serum levels of sICAM-1 were measured by enzyme-linked immunosorbent assay(ELISA), We evaluate invasive squamous cell carcinoma of the cervix (40), carcinoma in situ (16) and control (15) patients. Serum levels of sICAM-1 in healthy volunteers, in parients with carcinoma in situ and invasive cervical cancer were 150.1+/-41.3, 182.7+/-105.9, 189.8+/-60.0 ng/ml, respectively. Although the serum levels of sICAM-1 in patients with carcinoma in situ did not increase, serum levels of ICAM-1 in patients with invasive cervical cancer were significantly increased (control vs invasive cervical cancer, p < 0,05). From the above results, sICAM-1 is shed from the cancerous tissue in patients with squamous cell carcinoma of the cervix.
Asthma
;
Carcinoma in Situ
;
Carcinoma, Squamous Cell
;
Cervix Uteri
;
Colonic Neoplasms
;
Enzyme-Linked Immunosorbent Assay
;
Female
;
Healthy Volunteers
;
Humans
;
Immunohistochemistry
;
Intercellular Adhesion Molecule-1
;
Melanoma
;
Papillomavirus Infections
;
Prostatic Neoplasms
;
Uterine Cervical Neoplasms*
2.The film thickness and retention of cast crown using adhesive resin cements.
Young Wan JUNG ; Hye Won CHO ; Tai Ho JIN
The Journal of Korean Academy of Prosthodontics 1992;30(3):437-443
No abstract available.
Adhesives*
;
Crowns*
;
Resin Cements*
3.A study on the presence of anti-HBs at 4 years after hepatitis-B vaccination.
You Lan PYEON ; Wan Shin KIM ; Jung Jin CHO
Journal of the Korean Academy of Family Medicine 1992;13(1):35-41
No abstract available.
Vaccination*
4.A Comparative Study of Mental Health between the Laid-Off and the Employed Worker in the Similar Industry.
Sung Ae CHO ; Jin Joo JUNG ; Jung Wan KOO
Korean Journal of Occupational and Environmental Medicine 2003;15(4):335-343
OBJECTIVES: This study was conducted to examine the mental health status of the laid off by comparing the unemployed with the employed. METHODS: A survey questionnaire was used to investigate the mental health status of the laidoff in comparison with that of the employed. The study sample consisted of 247 laid-off people formerly employed in A auto factory and 167 employees working in B auto factory. RESULTS: The proportion exercising regularly was 20.2% for the laid-off and 34.8% for the employed and the proportion having regular meals was 10.9% and 50.6%, respectively. In addition, the frequency and amount of alcohol consumption and smoking of the laid-off were higher than those of the employed. Among the laid-off, 69.4% responded that they spent less time in talking to their spouse, and 65.4% also reported reduced sexual activities with their spouse. Because of unemployment, 41.8% of the laid-off experienced conflicts with their children, and 53.5% also perceived that they were stigmatized and treated badly by their neighbors, friends and relatives. Mean IFR in the laid-off was 22.9, which was much higher than the 15.3 recorded in the employed. The mean PWI-SF was 24.2 for the laid-off and 13.0 for the employed, which indicates the lower psychological health status of the laid-off than that of the employed. Age, annual salary, family relationship, regular exercise, regular diets, possibility to return to work and perception of the future were related to mental health status for the laid-off. Stepwise multiple regression analysis showed that the most important factor influencing mental health status for the laid-off was family relationships. CONCLUSIONS: According to the above results, the mental health of the laid-off is worse than that of the employed. Based on this study, a follow-up study focusing on the mental health status of the reemployed to the same factory, is needed to understand the direct mental health effect on the laid-off.
Alcohol Drinking
;
Child
;
Diet
;
Family Relations
;
Friends
;
Humans
;
Meals
;
Mental Health*
;
Questionnaires
;
Return to Work
;
Salaries and Fringe Benefits
;
Sexual Behavior
;
Smoke
;
Smoking
;
Spouses
;
Unemployment
5.Binding of fibronectin to staphylococcus aureus.
Jung Wan KIM ; Sang Hwa LEE ; Yoo Chul LEE ; Sung Yong SEOL ; Dong Taek CHO
Journal of the Korean Society for Microbiology 1993;28(6):431-441
No abstract available.
Fibronectins*
;
Staphylococcus aureus*
;
Staphylococcus*
6.The Clinical Significance of Absence of Umbilical Artery End-Diastolic Flow in Severe Pre-Eclampsia and Eclampsia.
Kook LEE ; Yong Seon CHO ; Lee Suk PARK ; Chul Wan JUNG ; Kyung SEO ; Jae Wook KIM
Korean Journal of Obstetrics and Gynecology 1999;42(8):1796-1801
To determine the perinatal mortality and morbidity of fetuses with absent end-diastolic velocities (AEDV) of the umbilical artery in severe pre-eclampsia and eclampsia, the outcome of 5 fetuses with AEDV was compared with that of 35 fetuses with positive end-diastolic velocities (PEDV). The study population comprised 38 cases of severe pre-eclampsia and 2 cases of eclampsia with structurally normal singletons, who had had umbilical artery Doppler velocimetry weekly from admission to delivery. The Doppler velocimetry result was not used for the clinical management. Perinatal death and neonatal morbidity from both groups were further examined in gestational age category to control the influence of preterm births. The incidence of AEDV of the umbilical artery Doppler velocimetry in severe pre-eclampsia and eclampsia was 12.5% (5/40). The AEDV group had a significantly higher incidence than the PEDV group in terms of ceasarean section due to fetal distress (60% : 17%), Apgar score < 7 at 5 minutes (60% : 14%), perinatal death (25% : 0%) and assisted mechanical ventilation (67% : 9%) both at 32-36 weeks. Time intervals from the detection of AEDV to delivery of live neonates varied from the day to 15 days. In conclusion, AEDV in the umbilical artery might be of clinical value in routine surveillance of pregnancies complicated by severe pre-eclampsia and eclampsia, and predict hypoxic fetal condition which needs operative interventions before or during labor and mechanical ventilation after birth.
Apgar Score
;
Cesarean Section
;
Dystocia
;
Eclampsia*
;
Female
;
Fetal Distress
;
Fetus
;
Gestational Age
;
Humans
;
Incidence
;
Infant, Newborn
;
Maternal Death
;
Mortality
;
Parturition
;
Parturition*
;
Perinatal Mortality
;
Pre-Eclampsia*
;
Pregnancy
;
Premature Birth
;
Respiration, Artificial
;
Rheology
;
Trial of Labor
;
Umbilical Arteries*
;
Uterine Rupture
7.Normal Fetal Echocardiography.
Seok Joong YOON ; Sung Jin HONG ; Hyung Gu CHO ; Jung Wan YOO ; Dong Chul PARK
Journal of the Korean Pediatric Society 1994;37(5):606-611
Fetal echocardiography is used by means of decleration of fetal cardiac anaztomy, to estabilish the diagnosis of congenital heart disease in utero. We attemped fetal echocardiography to ninty three pregnant women after intra uterine period 24 weeks, and estimated cardiac circumference, cardiac axis, pulmonary atery root diameter, arortic root diameter, diameter of inferior vena cava, diameter of superior ve studied how these estimates associate with following gestational na cava, and fractional shortening of ventricles. We ages. Cardiac axis was on the average 37.28 degree and cardiac apex was located in anterior left side of chest area. Aortic root diameter was 0.227 GA-0.043mm (GA=gestational age) at systolic phase, 0.203 GA+0.421mm at diastolic phase. Pulmonaly root diameter was 0.271 GA-0.029mm at systolic phase, 0.251 GA-0.067mm at diastolic phase. Thoracic aorta diameter was 0.195 GA+0.109mm at systolic phase, 0.198 GA+0.794mm at diastolic phase. Fractional shortening was 0.24 (1 Standard Deviation=0.11) in right ventricle, 0.23(1 SD=0.154) at left ventricle, and so ratio of right and left ventricle was 1.04(1 SD=0.51). Once normal fetal cardiac anatomy is understood, structural defects and/or alternation of function can be evaluated antenatally.
Aorta, Thoracic
;
Axis, Cervical Vertebra
;
Diagnosis
;
Echocardiography*
;
Female
;
Heart Defects, Congenital
;
Heart Ventricles
;
Humans
;
Pregnant Women
;
Thorax
;
Vena Cava, Inferior
8.Prophylaxis of fungal infection with fluconazole in neutropenic patients.
Jung Baik KIM ; Wan Kyoo EO ; Shi Young KIM ; Hwi Joong YOON ; Kyung Sam CHO
Korean Journal of Infectious Diseases 1993;25(1):45-49
No abstract available.
Fluconazole*
;
Humans
9.Serum Epeidermal Growth Factor Receptor (EGFR) in Cervical Cancer.
Chung Hyun LIM ; Yong Ho LEE ; Yoon Jung CHO ; Nak Woo LEE ; Young Tae KIM ; Kyu Wan LEE
Korean Journal of Gynecologic Oncology and Colposcopy 2000;11(1):67-75
Epidermal growth factor receptor (EGFR) is overexpressed in various malignancies including carcinoma of the breast, lung, esophagus, cervix, and stomach. In patients with cervical carcinoma, its overexpression may be associated with advanced stage and poor prognosis. So, we evaluated the levels of serum EGFR in patients with cervical carcinoma. The level of EGFR extracellular domain was determined in serum from 57 cervical carcinoma patients(adenocarcinoma: 2, squamous cell carcinoma: 39, carcinoma in situ(CIS): 16) and 28 cases of healthy control using enzyme-linked immunosorbent assay(Calbiochem). In invasive carcinoma, serum EGFR level was measured in 11 cases of Stage Ia, 9 cases of Stage Ib, 4 cases of Stage IIa, 15 cases of Stage IIb, 2 cases of stage III patients. The mean ages of the healthy controls, of the wome with carcinoma in situ(CIS), and with invasive cervical carcinoma were not different(49.3, 44,4, 49.5, respectively, p 0.241). The mean serum level of EGFR in healthy control(n 28), carcinoma in situ(CIS)(n 16), and invasive carcinoma patients(n=41) were not significantly different(71.4+/-12.8fmol/ml, 79.2+/-26.8fmol/ml, 61.8+/- 18.4 fmol/ml, respectively, p=0.071). In conclusion, the expression of EGFR was not increased in patients with cervical cancer compared with normal women. And no significant differences were found depending on the clinical stage.
Breast
;
Carcinoma, Squamous Cell
;
Cervix Uteri
;
Enzyme-Linked Immunosorbent Assay
;
Esophagus
;
Female
;
Humans
;
Lung
;
Prognosis
;
Receptor, Epidermal Growth Factor
;
Stomach
;
Uterine Cervical Neoplasms*
10.EFECTS OF LATERAL GUIDANCE AND CHEWING PATTERN ON MASTICATORY MUSCLE ACTIVITY AND OCCLUSAL CONTACT.
Joon Won KOH ; Young Wan JUNG ; Ifye Won CHO ; Tae Ho JIN
The Journal of Korean Academy of Prosthodontics 1998;36(4):598-614
This study was performed to investigate the influence of lateral guidance pattern and chewing pattern on masticatory muscle activity and occlusal contact pattern. Twenty-five patients with temporomandibular disorders and thirty students without temporomandibular disorders were selected for this study. Electromyographic examination and occlusal contact examination were performed simultaneously with Bio-Pak System(Bioresearch Inc.,U.S.A.) and T-Scan System(Tekscan Co., USA). The obtained results were as follows : 1. The EMG activity of masseter and anterior temporal muscle in patient group with canine guidance was higher than with non-canine guidance, but there was no significant difference(p>0.05). 2. The EMG activity of anterior temporal muscle in normal group with non-canine guidance was higher at preferred chewing side than at opposite side(p<0.05). 3. The EMG activity of masseter muscle was higher in normal group than in patient group (p<0.05). 4. The number of occlusal contact in patient group with canine guidance was higher than with non-canine guidance, but there was no significant difference(p>0.05). 5. The occlusal contact force at preferred chewing side was higher in patient group than in normal group(p<0.05).
Dental Occlusion
;
Humans
;
Masseter Muscle
;
Mastication*
;
Masticatory Muscles*
;
Temporal Muscle
;
Temporomandibular Joint Disorders