A case of postradiation sarcoma, found in a 52-year-old woman, who underwent a total hystrectomy under the diagnosis of cervical cancer 12 years ago, followed by radiation therapy. The tumor invasion was extensive involving the left innominate bon and upper end of the left femur including the head and neck. Histopathological findings revealed sarcomatous change with atypical osteoid formation and stromal proliferation. The case has been followed for 2 years since February 1974 and survives today.
Diagnosis ; Female ; Femur ; Head ; Humans ; Middle Aged ; Neck ; Osteosarcoma ; Pelvic Bones ; Sarcoma ; Uterine Cervical Neoplasms

Injuries in the industries has been steadily increasing in this country in recent years. Injuries in the industries intricate in accoriance with the industrial environment, mechanism of injuries and the other factors of employees. In 6 years 201 patients with industrial injuries underwent treatment in the Department of Orthopaedic Surgery of the National Medical Center, and the result of treatment is reported in this paper. 1. 70 cases out of 201 cases were in the age group between 21 to 30 year. 186 cases were male and 15 were female. The incidence is remarkably higher in male. 2. In 80 cases the injuries were caused by machinery with pressor parts. The patients were chiefly manual workers in factories. 3. Of 280 injuries, 148 (62.8%) were upper extremities, 105 (37.5%) were lower extremities and 27 (96%) were trunks. The most common site of injuries was hand. 4 Of 146 injuries with fractures, 94 were treated by manual reduction and cast, and 52 were treated by open reduction. 5. Treatment for open wounds was debridement followed by delayed primary closure and/or skin graft. The primarily closed open wounds by local clinics were observed and treated according to wound condition. 6, 17 cases out of 22 phalangeal bone fractures were treated by manual reduction and splint. 5 cases were treated by K-wire internal fixation, among them 3 cases had to be treated by amputation. 7. Incidence of early camplication was considerably high with 137 sites out of 280 sites and the late complication was 79 sites after treatment of the early complications.
Amputation ; Debridement ; Female ; Fractures, Bone ; Hand ; Humans ; Incidence ; Lower Extremity ; Male ; Skin ; Splints ; Transplants ; Upper Extremity ; Wounds and Injuries

Malignant thymoma is usually manifested as a mediastinal mass. Occasiomally, these tumors may be associated with a variety of systemic syndromes, such as myasthenia gravis, pure red cell aplasia or hypogammaglobulinemia. However, it is generally accepted that thymomas rarely metastasize and the frequency of extrathoracic metastasis has been reported as 1 to 15%. In general, nuclear changes of tumor cells such as enlarged size, irregular shape and altered textures are determining feactors in the assessment of the grade of malignancy. We experienced a case of malignant thymoma of anterior mediastinum in a 35-year-old woman. After 3 years, she developed recurrent malignant thymoma in the right supraclavicular area, diagnosed by aspiration biopsy cytology.
Adult ; Agammaglobulinemia ; Biopsy, Fine-Needle* ; Biopsy, Needle ; Female ; Humans ; Mediastinum ; Myasthenia Gravis ; Neoplasm Metastasis ; Red-Cell Aplasia, Pure ; Thymoma*

Juvenile dermatomyositis is a common inflammatory muscle disease of childhood, characterized by weakness in proximal muscles and specific skin rash. In case of juvenile dermatomyositis without characteristic clinical features, non-invasive imaging tools such as (99m)Tc-HDP three-phase bone scan are very helpful in diagnostic workup of myopathies. We report a case of 13-year old female with juvenile dermatomyositis, in which (99m)Tc-HDP three-phase bone scan was useful in diagnosis and assessing therapy response.
Dermatomyositis ; Exanthema ; Female ; Humans ; Muscles ; Muscular Diseases ; Myositis

OBJECTIVE: Helicobacter pylori (H. pylori) has been implicated in the pathogenesis of chronic gastritis, gastric ulcer, duodenal ulcer and gastric cancer. Histological examination and culture are considered to be the most specific tests, and rapid urease test and serological test are rapid but less specific tests. 'I he aim of this study was to investigate the efficiency of the polymerase chain reaction (PCR) assay as a procedure for the diagnosis of H, pylori infection in gastric biopsy specimens. METHODS: Biopsy specimens were obtained from the gastric antrum within 2cm from the pyloric channel of 42 patients during endoscopy and submitted for the histological examination, CLO test, and PCR assay. At the same time, another biopsy specimens were obtained from the lesion for the diagnosis of the diseases. Also, blood was sampled for the measure of the value of IgM and IgG. RESULTS: As the result of the histopathological examination, chronic gastritis was diagnosed in 13 patients, gastric ulcer in 11, duodenal ulcer in H, and gastric cancer in 10. By the histological examination of the antrum, H, pylori were found in 77% of chronic gastritis, 55% of gastric ulcer, 75% of duodenal ulcer, and 40% of gastric cancer. As a whole, the bacteria was identified in 62%, 60%, 88%, 90%, 69% of patients by histological test, CLD test, IgM, IgG, and P(;R respectively. The gold standard we used for the presence of bacteria was histological examination. Sensitivity, specificity, positive predictive value, ancl negative predictive value for PCR assay were 92%, 69%, 83% and 85% respectively. The results of other test were as follows. CLO test: 89%, 88%, 92%, 82%, IgM:92%, 19%, 65%, 60%, IgG:100%, 25%, 68%, 100%. CONCLUSION: CR is a very sensitive but some- what less specific test for the detection of H. pylori. This is mainly due to the contamination of H. pylori during endoscopy and biopsy. So, minimization of the contamination would make PCR clinically useful test.
Bacteria ; Biopsy* ; Diagnosis ; Duodenal Ulcer ; Endoscopy ; Gastritis ; Helicobacter pylori* ; Helicobacter* ; Humans ; Immunoglobulin G ; Immunoglobulin M ; Polymerase Chain Reaction* ; Pyloric Antrum ; Sensitivity and Specificity ; Serologic Tests ; Stomach Neoplasms ; Stomach Ulcer ; Urease

Many disorders and abnormalities are accompanied by cavitary lesoin of the lung and one of the most common causes of cavitary lung disease are primary and metastatic lung neoplasms. but cavitary formation of primary lung cancer is not frequent and cavitary or cystic pulmonary metastases of this is also rare. We report a case of cavitary pulmonry metastases of primary lung cancer proven by bronchoscopic biopsy and chest CT. The patients was 60 year-old heavy smoker who had never been underlying lung diseases 7 years ago and complained chronic cough. The chest CT showed primary lung cancer in right low lobe with multiple cavitary or cystic metastases in both lungs and multiple lymphatic metastases.
Biopsy ; Neoplasm Metastasis ; Lung Neoplasms

Adrenal Cortex Hormones ; Autoantibodies ; Blister ; Cell Separation ; Epithelium ; Extracellular Space ; Female ; Humans ; Immunosuppressive Agents ; Keratinocytes ; Mouth Mucosa ; Oral Ulcer ; Pemphigus ; Plasminogen ; Skin

BACKGROUND/AIMS: Noncardiac chest pain (NCCP) mainly results from esophageal lesions in the developed world. By contrast, gastroesophageal reflux disease (GERD) is a less frequent cause of NCCP than peptic ulcer disease in China and Japan. Therefore, both esophageal lesions and stomach and duodenal lesions are likely to be important causes of NCCP in Korea. We used upper gastrointestinal endoscopy to evaluate lesions of the esophagus, stomach, and duodenum in NCCP patients after cardiac chest pain was ruled out by coronary angiography (CAG). METHODS: From the patients who underwent CAG between 2004 and 2008, we identified 89 patients who had normal CAG or minimal disease. We retrospectively analyzed the endoscopic findings of these 89 patients who were diagnosed with NCCP. RESULTS: At endoscopy for the 89 patients, the percentages of GERD, gastric ulcer, and duodenal ulcer were 20.2% (n=18), 14.6% (n=13), and 3.3% (n=3) respectively. Of the 16 cases diagnosed as peptic ulcer, 11 were evaluated by biopsy or the Campylobacter-like organism (CLO) test for suspected Helicobacter pylori infection. Six (54%) cases were positive for H. pylori and five (46%) were negative. CONCLUSIONS: In Korea, the incidence of peptic ulcer disease (17.9%) as a cause of NCCP is similar to that of GERD (20.2%). Consequently, we should perform endoscopy to determine the cause of NCCP.
Biopsy ; Chest Pain ; China ; Coronary Angiography ; Duodenal Ulcer ; Duodenum ; Endoscopy ; Endoscopy, Gastrointestinal ; Esophagus ; Gastroesophageal Reflux ; Helicobacter pylori ; Humans ; Incidence ; Japan ; Korea ; Peptic Ulcer ; Retrospective Studies ; Stomach ; Stomach Ulcer ; Thorax

OBJECTIVES: The in-training examination (Performance Examination, PE) for psychiatric residents in Korea was launched 5 years ago by the Korean Neuropsychiatric Association (KNPA). This article analyzes 5-year accumulated data on the PE, and tries to make some suggestions for further development of the PE. METHODS: The 5-year data, previously utilized for the generation of formal annual reports were reanalyzed, with an emphasis on longitudinal trends. RESULTS: The analyses indicated the following; 1) Higher-year residents earned definitely higher scores than their lower-year colleagues on the PE. This trend was especially prominent in the area of psychopharmacology-biological psychiatry, geriatric psychiatry, child and adolescent psychiatry, and the emergency-organic psychiatry. There was no year-related performance difference in the area of psychoses. 2) In the area of anxiety-somatization disorder, psychophysiological disorder, and geriatric psychiatry, the residents in the university-affiliated hospitals outperformed those in the specialized psychiatric hospitals. 3) Through analyzing multiple-times examinees, it was found that their first-and second-time performances were moderately correlated, and that their ranks tended to improve, demonstrating a continuously improving performance according to the training year. CONCLUSION: These result suggested that the KNPA PE is a feasible measure for the estimation of an individual resident's performance as well as the adequacy of the environment provided by the training institutes.
Academies and Institutes ; Adolescent ; Adolescent Psychiatry ; Child ; Child Psychiatry ; Geriatric Psychiatry ; Hospitals, Psychiatric ; Humans ; Korea ; Psychophysiologic Disorders ; Psychotic Disorders

Salmonella infection occurs in 5 different clinical forms; gasteroenteritis, enteric fever, bacteremia, chronic carried state and localization at one or more sites. Extraintestinal pyogenic infections caused by salmonella species include soft tissue abscesses, bone and joint infections, cholecystitis, liver abscess and splenic abscess etc. Pancreatic abscess due to Salmonella typhi is a very rare extraintestinal manifestation of salmonellosis. Infection pathways may be considered as reflux of infected bile through the pancreatic duct, hematogenous spread from a distant site or lymphatic spread from the intestinal tract. Treatment of pancreatic abscess needs surgical intervention and antibiotics therapy. We have experienced a case of a 40-years-old female with pancreatic abscess due to Salmonella typhi. She was treated with ultrasonography-guided catheter drainage and intravenous ceftriaxone for 18 days. After 14 days, the sonographic examination revealed the abscess cavity in pancreas almost disappeared. We report this case with review of literatures.
Abscess* ; Anti-Bacterial Agents ; Bacteremia ; Bile ; Catheters ; Ceftriaxone ; Cholecystitis ; Drainage ; Female ; Humans ; Joints ; Liver Abscess ; Pancreas ; Pancreatic Ducts ; Salmonella Infections ; Salmonella typhi* ; Salmonella* ; Typhoid Fever ; Ultrasonography