The histochemical study, especially the demonstration of alkaline phosphatase and acid phosphatase was carried out in order to differentiate ascarides of human and pigs. The experimental material were obtained from naturally contaminated men and pigs. As the histochemical staining methods the Gomori's was applied for acid phosphatase and Takeuchi and Takami's for alkaline phosphatase. The results obtained were summerized as follows : In the pig's ascarides, alkaline phosphatase was richly found in the subcuticular tissue, lateral line, median line, strial zone and epithelial cells of the intestine, epithelial cell and basal membrane of the ovary, the same part of the uterus and also in eggs. Acid phosphatase in the pig's ascarides were distributed in the same part as alkaline phosphatase. It, however, was darker brown in the soft tissue of the lateral line, epithelium of excretory canal, median bundle, whole zone of the intestine and intestinal contents. In the human ascarides, the alkaline phosphatase was distributed in the testes and the parts where the acid phosphatase was found in the pig ascarides. The acid phosphatase in the human ascarides was demonstrated in the subcuticular tissue, soft tissue of lateral line, epithelium of excretory cells, strial zone, transparent zone, granular zone and epithelial zone of esophagus and intestine, ovary, ova in the uterus, epithelial cell and basal membrane of the uterus and in testes. In the pig's ascarides, the area of distribution of alkaline phosphatase was restricted, but that of acid phosphatase was wider. In human ascarides, the area of distribution of alkaline phosphatase and acid phosphatase was not significantly different, but in some part showed slight difference. Above mentioned finding suggest that the distribution of phosphatase could be utilized for the differentiation of ascarides of human and pig.
parasitology-helminth-nematode-Ascaris lumbricoides ; Ascaris suum ; histochemistry ; differentiation ; alkaline phosphatase ; acid phosphatase ; animal ; human ; pig

Disseminated superficial actinic porokeratosis (DSAP) is one of the recently found skin disorderes, which was differentiated from classicaI porokeratosis (Mibelli) and senile keratosis etc. in view of clinical features and hietogenesis by Marvin E. Chernosky on 1967. The one was 60 years old female patient, who had been suffered from multiple dark-brownish keratotic uniform minute papules on dorsa of the hands, forearms and neck with accompanying itching sensation since about 20 year's old of her age. The another one was 38years old housewffe, wha had been suffered from same lesions of the former on the face, neck, extremities especially sun-light exposed area. In both cases, skin lesions were exacerbated during each summer season and increase in numbers of the skin lesions with more severe itching sensation. Chernosky postulated none of a dark-sklnned race affording natural protection against sun-light had skin lesion of D S A P, we were abIe to find out two cases of typical D S A P ih the Korea.
Continental Population Groups ; Extremities ; Female ; Forearm ; Hand ; Humans ; Keratosis ; Korea ; Middle Aged ; Neck ; Porokeratosis* ; Pruritus ; Seasons ; Sensation ; Skin

No abstract available.
Animals ; Gene Expression* ; Genes, Immediate-Early* ; Rats*

Sixty four leprous claw hands had been operated on for intrinsic replacement extensor-extensor many tailed at the Department of Orthopedic Surgery, Kyungpook National University Hospital during the period from 1966 to 1970. The follow up study was carried out for fourty-one hands from one year to four years and nine months after operation, and evaluated by the following assessments. 1. Fully open hand assessment 2. Lumbrical position assessment 3. Hook position assessment 4. Closed fist assessment 5. Mechanics of closing 6. Separate finger movement in lumbrical position The results obtained were as follows: 1. The most of the cases were median-ulnar palsy. 2. The majority of them were in third decade young men. 3. Satisfactory result was 63.5% in appearance, 70.8% in function, 62.8% according to the patients statement, and 61.1% in overall total assessment. 4. As complication two cases of severe adhesion of the grafted tendons and significant lateral deviation on nine fingers were noted. 5. Preoperative and postoperative physiotherapy contributed a important roll in the end results.
Animals ; Fingers ; Follow-Up Studies ; Gyeongsangbuk-do ; Hand ; Hoof and Claw ; Humans ; Male ; Mechanics ; Orthopedics ; Paralysis ; Tail ; Tendons ; Transplants

Biopsy has proved to be of value in the diagnosis of many inflammatory and malignant diseases, and needle biopsy of the synovial membrane in arthritis is well established and often employed as the final diagnostic aid in patient with joint disease. Authors have carried out synovial needle biopsy in 76 joints with Franklin-Silverman needle used commonly in liver biopsy. The results obtained were as followa; 1) Of seventy five biopsies attempted, adequate amount of tiasue was obtained in 51 of 53 knee cases (96.2%), 11 of 14 wrists (78.6%). 3 of 5 elbows (60%), 1 of 3 ankles (33.3%). Adequate amount of tissue was obtained in 66 cases and the overall succese rate was 88%. 2) Histopathological diagnosis was made in 53 of 75 cases (70.7%). In 12 cases, correct specimens were obtained but proved to be incompatible with the diagnosis done by either clinical data or open biopsy. 3) Histopathological diagnoses were made in 25 of 35 cases of rheumatoid arthritis (71.4%) 14 of 18 cases of tuberculous arthritis (77.8%), 7 of 13 cases of degenerative arthritis (53,8%), 4 of 6 cases of suppurative arthritis (66.7%), 2 cases of traumatic arthritis (100%), and one case of villonodular synovitis (100%). 4) The complications resulting from this proedure were pare; mild transient hemarthrosis was found in only 5 cases We also discovered that for an accurate diagnosis multiple specimens should be obtained because otherwise the specimens were too small to interprete histopathologically. In addition we concluded that the success rate depended not upon the sorts of needle used but rather more upon the biopsy technique. Franklin-Silverman needle biopsy proved to be a simple, safe and reliable procedure for diagnosis of the synovial diseases in which conventional arthrotomy is inadvisable and other diagnostic procedures are inadequate.
Ankle ; Arthritis ; Arthritis, Infectious ; Arthritis, Rheumatoid ; Biopsy ; Biopsy, Needle ; Diagnosis ; Elbow ; Hemarthrosis ; Humans ; Joint Diseases ; Joints ; Knee ; Liver ; Needles ; Osteoarthritis ; Synovial Membrane ; Synovitis ; Wrist

Glomus tumor is a painful small subcutaneous mass as described by William Wood in 1812. Although seen infrequently and difficult to diagnose, the tumor has been interest to the profession for many years. The normal glomus is an end-organ apparatus which is a remarkable arteriovenous anastomosis functioning without an intermediary capillary bed. Distributed widely over the surface of the body in the deepest layer of the corium or in the stratum reticuiare of the skin, it is most abundant at the distal ends of the extremities. The main function of the glomus body is to aid in the regulation of the skin circulation and, therefore, the peripheral blood pressure and temperature. Glomus tumor represents a hypertrophy of the normal glomus. The gross appearance is that of small soft encapsulated tumor, pink or purple in color, almost always less than one centimeter in diameter if it is located subungually. The microscopic appearance of the tumor closely resembles that of normal glomus, the principal difference being a marked increase in the number of glomal cells (epithelioid cells) and nonmyelinated nerves. Glomus tumor may occur at any age but is most frequent in the middle age of life. Pain, tenderness and temperature sensitivity are the classic triad of symptoms. Complete surgical excision is the treatment of choice for the glomus tumors. Successful removal of the tumor leads to complete relief of pain and return to normal function. This paper is aimed to report on our experience with 3 cases of subungual glomus tumor which were successfully treated by complete excision and to review the literature.
Arteriovenous Anastomosis ; Blood Pressure ; Capillaries ; Dermis ; Extremities ; Glomus Tumor ; Humans ; Hypertrophy ; Middle Aged ; Skin ; Wood

No abstract available.
Animals ; Liposarcoma* ; Mice ; Mice, Nude*

No abstract available.
Hemophilia A* ; Humans ; Intussusception*

Congenital pseudarthrosis is frequently associated with various stigmata of neurofibromatosis, particularly Cafe-Au-Lait spots and,subcutaneous nodules and in these patients, it is noteworthy that the treatment is very difficult even with extensive operative approach. Also it is interesting to find many controversies on etiological relation between neurofibroma and pseudarthrosis, per se and even the existance of nerve element in and around the tissue of pseudarthrosis. A thirteen years old female patient with definite neurofibromatosis associated with congenital tibial pseudarthrosis treated by intramedullary nailing and massive bone graft is reported.
Cafe-au-Lait Spots ; Christianity ; Female ; Fracture Fixation, Intramedullary ; Humans ; Neurofibroma ; Neurofibromatoses ; Pseudarthrosis ; Transplants

We herein report a case of transient acrodermatitis enteropathica in a 3-month-old, breast-fed, full-term infant. The patient was presented with a 2-month history of diarrhea and crusted erythema- tous patches on the periorificial area. Similar lesions were seen in his siblings. His serum zinc level and the zinc level in his mother's breast milk were markedly reduced. Diarrhea and skin lesions disappeared promptly with oral zinc supplementation and did not recur when zinc was discontinued after three weeks. Our case indicates that even full-term infants, who feed excl-usively on mothers milk, run a risk of developing zinc deficiency, if the concentration of zinc in the breast milk is very low.
Acrodermatitis* ; Diarrhea ; Humans ; Infant* ; Milk ; Milk, Human ; Mothers ; Siblings ; Skin ; Zinc