PURPOSE: We studied prevention effects of vertical transmission of Hepatitis B with follow-up, through the change of Anti-HBs titers during 9 months after injection of Hepatitis B immunoglobulin (HBIG) and Hepatitis B vaccine (HBV) at birth in newborn delivered from Hepatitis antigen carrier mothers. METHODS: This study was performed on newborn delivered from HBsAg carrier mothers at Hae Sung Hospital from Feb. 1995 to May 1996. These newborn were injected intramuscularly with HBV and HBIG after evaluation of HBsAg and Anti-HBs titer directly at birth. Regular Hepatitis vaccination was given at 1 month, 6 months as well as HBsAg and Anti-HBs titer were evaluated at 24 hours, 1 month, 3 months, 6 months, and 9 months. RESULTS: The incidence of Hepatitis B carrier mothers is 5.6%, and newborn babies born to HBsAg carrier mothers showed HBsAg in 10.6%. In most newborn, Anti-HBs titer maintained in 100-1,000mIU/ml after injection of HBIG and HBV at birth, and mean Anti-HBs titer decreased a little at 1 month, but therafter increased gradually by regular Hepatitis vaccination. HBsAg positive newborn maintained mean HBsAg titers below 2 (S/N) until 9 months old after injection of HBIG and HBV. CONCLUSIONS: A screening test for Hepatitis B must be performed on all pregnant women, and that infants of Hepatitis B carrier mothers must be immunized by HBIG and HBV directly at birth.
Female ; Follow-Up Studies ; Hepatitis ; Hepatitis B ; Hepatitis B Surface Antigens* ; Hepatitis B Vaccines ; Humans ; Immunoglobulins ; Incidence ; Infant ; Infant, Newborn* ; Mass Screening ; Mothers* ; Parturition ; Pregnant Women ; Vaccination

The purpose of this study were to examine the effects of the speed of sidestep in a specific direction on the kinematic variables of the lower extremities and to provide basic information on sidestep. The subjects of this study were eight students at Hanseo University who did not have a problem in lower extremity alignment. Biomechanical data were collected using a motion analysis system and force plate and Kruskal-Wallis test was performed in order to test differences according to speed. The results of this study were as follow. First, as to hip joint angle according to speed, when the speed increased, in the sagittal view, the maximum flexion angle decreased, the range of motion (ROM) decreased, and the flexion angle at the highest ground reaction force decreased, and in the transverse view, the internal rotation angle at the highest ground reaction force increased. Second, as to knee joint angle according to speed, when the speed increased, in the sagittal view, the maximum flexion angle decreased, the ROM decreased, and the flexion angle at the highest ground reaction force decreased, and in the coronal view, the maximum varus angle decreased, and the ROM decreased. Third, as to ankle joint angle according to speed, when the speed increased, in the sagittal view, the ROM decreased, and the dorsiflexion angle at the highest ground reaction force decreased, and in the coronal view, the minimum inversion angle increased. This suggests that high-speed sidestep during a game increases the risk of injury and degenerative arthritis among athletes.
Ankle Joint ; Athletes ; Biomechanical Phenomena ; Genu Varum ; Hip Joint ; Humans ; Joints* ; Knee Joint ; Lower Extremity* ; Osteoarthritis ; Range of Motion, Articular

No abstract available.
Adenocarcinoma* ; Fallopian Tubes* ; Female

No abstract available.
Hemoptysis*

PURPOSE: To investigate the effects of Anti-TNF-alpha (infliximab, Remicade(R), Shering-Plough) on refractory uveitis. METHODS: A retrospective observational survey was conducted on 12 eyes of 10 patients with refractory uveitis. These patients had no response to immunosuppresants or systemic steroid therapy and were intolerable due to drug toxicity. After an intravenous injection of Anti-TNF-alpha, best corrected visulal acuity was measured. Improvement in inflammation was then observed at the first, third and last month of follow-up. RESULTS: Patients were observed for a mean period of 15 months. They received anti-TNF-alpha intravenously, ranging from one to eleven infusions. After infusion with Anti-TNF-alpha, remission of intraocular inflammation was evident in all patients within 9.7 days. Best corrected visual acuity also improved at the first, third, and last month of follow-up. Two patients were infected by tuberculosis and mumps respectively. CONCLUSIONS: There was an effect on refractory uveitis with anti-TNF-alpha therapy. Many participants may also require further evaluation after treatment.
Drug-Related Side Effects and Adverse Reactions ; Follow-Up Studies ; Humans ; Inflammation ; Injections, Intravenous ; Mumps ; Retrospective Studies ; Tuberculosis ; Uveitis* ; Visual Acuity

PURPOSE: To establish the CT findings and clinical characteristics of colorectal mucinous adenocarcinoma. MATERIALS AND METHODS: The CT features of 26 surgically proven cases of colorectal mucinous adenocarcinoma were reviewed. The subjects were selected from among 262 patients with colorectal cancer, of whom 40 with non-mucinous adenocarcinoma were included as a control group. Contrast-enhaneed CT images were analyzed for tumor location, the presence or absence of tumoral calcification, tumor shape (circumferential or eccentric, polypoid or infiltrative), tumor thickness-to-length ratio, and attenuation and homogeneity. In each group, the TNM stage of pathologic specimens was compared. During follow-up, the incidence of recurrence, and outcome, were also compared. RESULTS: CT images of mucinous adenocarcinoma revealed intratumoral calcification in three patients (12%, p < 0.01). Tumors were eccentric and polypoid-shaped, with a high tumoral thickness/length ratio (p < 0.01). On contrast-enhanced images, most were seen as a heterogenous hypoattenvuted mass. No differences in T-NM stage were found in surgical specimens. In patients with mucinous adenocarcinoma, recurrence during the early follow-up period is more common than in patients with non-mucinous cancer. CONCLUSION: Contrast-enhanced CT reveals mucinous adenocarcinoma as an eccentric polypoid mass with heterogeneous hypoattenuation. In patients with mucinous colorectal cancer, careful follow-up is required because tumors tend to recur early in the follow-up period.
Adenocarcinoma ; Adenocarcinoma, Mucinous* ; Colorectal Neoplasms ; Follow-Up Studies ; Humans ; Incidence ; Mucins* ; Recurrence ; Tomography, X-Ray Computed

PURPOSE: To establish the CT findings and clinical characteristics of colorectal mucinous adenocarcinoma. MATERIALS AND METHODS: The CT features of 26 surgically proven cases of colorectal mucinous adenocarcinoma were reviewed. The subjects were selected from among 262 patients with colorectal cancer, of whom 40 with non-mucinous adenocarcinoma were included as a control group. Contrast-enhaneed CT images were analyzed for tumor location, the presence or absence of tumoral calcification, tumor shape (circumferential or eccentric, polypoid or infiltrative), tumor thickness-to-length ratio, and attenuation and homogeneity. In each group, the TNM stage of pathologic specimens was compared. During follow-up, the incidence of recurrence, and outcome, were also compared. RESULTS: CT images of mucinous adenocarcinoma revealed intratumoral calcification in three patients (12%, p < 0.01). Tumors were eccentric and polypoid-shaped, with a high tumoral thickness/length ratio (p < 0.01). On contrast-enhanced images, most were seen as a heterogenous hypoattenvuted mass. No differences in T-NM stage were found in surgical specimens. In patients with mucinous adenocarcinoma, recurrence during the early follow-up period is more common than in patients with non-mucinous cancer. CONCLUSION: Contrast-enhanced CT reveals mucinous adenocarcinoma as an eccentric polypoid mass with heterogeneous hypoattenuation. In patients with mucinous colorectal cancer, careful follow-up is required because tumors tend to recur early in the follow-up period.
Adenocarcinoma ; Adenocarcinoma, Mucinous* ; Colorectal Neoplasms ; Follow-Up Studies ; Humans ; Incidence ; Mucins* ; Recurrence ; Tomography, X-Ray Computed

BACKGROUND: Pleural eosinophilia is rare and commonly considered to be an indicator of good prognosis. The diagnostic significance of eosinophilic pleural effusions remains controversial despite a century of observation and discussion. This study was conducted to assess the prevalence of eosinophilia in 446 consecutive samples of pleural fluid, to review the cause of eosinophilic pleural effusion and to determine whether the presence of eosinophils increases the likehood of benign conditions. METHOD: A retrospective analysis was performed upon patients that underwent first thoracentesis due to pleural effusion between January 1999 and December 1999. RESULTS: Eosinophilic pleural effusions were identified in 24 of the 446 patients (5.4%). Malignancy, parapneumonic effusion and tuberculosis were determined the major causes of pleural effusion (80.6%). Malignancy was diagnosed as frequently in eosinophilic effusions as in non-eosinophilic effusions (54.2% vs 50.5%, p=0.725). No difference was found in the prevalence of eosinophilic and non-eosinophilic effusion according to the etiology. The mean blood eosinophil ratio in patients with eosinophilic pleural effusion was 5.4% and no significant correlation existed between the blood and pleural eosinophilic count. CONCLUSION: Pleural eosinophilia is not helpful for differentiating benign and malignant etiology and is not related with blood eosinophilia or repeated tapping.
Eosinophilia ; Eosinophils* ; Humans ; Pleural Effusion* ; Prevalence ; Prognosis ; Retrospective Studies ; Tuberculosis

PURPOSE: To assess the usefulness of percutaneous drainage of abscess in the treatment of emphysematous pyelonephritis. MATERIALS AND METHODS: Ten cases of nine patients with emphysematous pyelonephritis were percutaneously drained. All were suffering from diabetes mellitus. The procedure was performed under fluoroscopic guidance in nine cases and US guidance in one case in which bilateral multiloculated abscesses were present in the perirenal spaces. The results were classified as cure, partial success, recurrence, or failure. The mean drainage period and complication were analyzed. RESULTS: Eight cases were cured, and there was one partial success. In one case, who had diffuse renal parenchymal destruction without perirenal fluid collection, the treatment failed. The longest drainage period was 45 days, in a case of re-insertion due to incidental catheter removal ; the mean was 23 days. Bacteremia in one case was cured with antibiotic therapy which lasted two days. CONCLUSION: In diabetic patients, percutaneous drainage of abscess is thought to be a safe and effective method for the treatment of emphysematous pyelonephritis, and is one that does not involve diffuse destruction of renal parenchyma.
Abscess* ; Bacteremia ; Catheters ; Diabetes Mellitus ; Drainage* ; Humans ; Pyelonephritis* ; Recurrence

Primary CNS lymphoma (PCNSL) which is localized in the cauda equina of the spinal cord is very rare. A 75-year-old man had pain in both legs and gait disturbance for the last 45 days. Painful paresthesia and weakness in both legs worsened during a one month period and he was unable to stand up by himself. In a physical examination, lym-phadenopathy nor organomegaly was found. A neurological examination revealed a dominantly proximal muscle weak-ness of the lower extremities. All modalities of sensation were decreased in both legs and a Romberg test was found positive. A CSF cytology demonstrated a large B-cell lymphoma. Following an extensive evaluation of the patient, the lymphoma was found to be limited in the cauda equina. The patient was treated with systemic dexamethasone. After the treatment, his symptoms were improved and a follow up lumbar spine MRI showed shrunken cauda equina lesions.
Aged ; Cauda Equina* ; Dexamethasone ; Follow-Up Studies ; Gait ; Humans ; Leg ; Lower Extremity ; Lymphoma* ; Lymphoma, B-Cell ; Magnetic Resonance Imaging ; Neurologic Examination ; Paresthesia ; Physical Examination ; Polyradiculopathy* ; Sensation ; Spinal Cord ; Spine