No abstract available.
Female ; Methotrexate* ; Pregnancy ; Pregnancy, Tubal*

We report two cases of malignant schwannoma of skin in association with non-familial neurofibromatosis. Case 1, a 47 year old man, had a large subcutaneous tumor on the sacral area and case 2, a 62 year old woman, a painful, ulcerating tumor on the posterior aspect of the left arm. Both cases were histopathologically confirmed as malignant schwannomas and immunohistochemical studies showed 5-100 protein in the tumor cells. After surgical excision of the tumors, case 1 was lost to follow up, while case 2 remained without evidence of disease for more than one and half years.
Arm ; Female ; Humans ; Lost to Follow-Up ; Neurilemmoma* ; Neurofibromatoses* ; Skin ; Ulcer

BACKGROUND: Acid-base derangement are commonly encountered in critically ill patients. This study is to investigate underlying mechanisms of acid-base imbalance and also to examine whether they can predict mortality in burn patients. METHODS: We retrospectively reviewed 73 severely burned patients who had admitted to burn intensive care unit, from January to July in 2004. All the patients had inhalation injury, identified by bronchoscopic examination. We analyzed the type and nature of the acid-base imbalances from arterial blood gas analysis, electrolytes and other biological tests between survivors and non-survivors for 30 days after admission. RESULTS: Acidosis was the most common disorder during the early and late hospital periods. Large fractions of those showed decreased strong ion difference (SID), increased anion gap corrected by albumin (AGc) and [Cl-]corrected. Mixed disorder and alkalosis emerged after the 7(th) hospital day. As time went by, albumin, PaO2/FiO2 ratio, pH and SID were more decreased in non-survivors (n=28) than in survivors (n=45) while [Cl-] corrected, alveolar-arterial oxygen tension gradients, peripheral WBC counts and CRP were more increased in non-survivors than in survivors. In the area under the receiver operating characteristic curves for mortality prediction, APACHE II score and % of total body surface area (%TBSA) burn were high: 0.866 (95% CI; 0.785~0.946) for APACHE II score, 0.817 (95% CI; 0.717~0.918) for %TBSA burn. CONCLUSIONS: In burned patients with inhalation injury, various types of acid-base imbalances and electrolytes abnormalities emerged after resuscitation and so, more careful attentions pursued for correcting underlying acid-base derangement.
Acid-Base Equilibrium ; Acid-Base Imbalance* ; Acidosis ; Alkalosis ; APACHE ; Attention ; Blood Gas Analysis ; Body Surface Area ; Burns* ; Critical Illness ; Diagnosis* ; Electrolytes ; Humans ; Hydrogen-Ion Concentration ; Inhalation* ; Intensive Care Units ; Mortality* ; Oxygen ; Resuscitation ; Retrospective Studies ; ROC Curve ; Sudden Infant Death ; Survivors

No abstract available.
Leukemia, Plasma Cell* ; Plasma Cells* ; Plasma*

Gastric cancer is the most prevalent gastrointestinal tract malignancy in Korea. By the time the patient hassymptoms, these tumors are usually advanced in stage. In high risk populations,screening such as double contrastUGI or gastric endoscopy is needed and patient with vague symptoms should be studied. However, these screeningshave high diagnostic accuracy rate, only CT scan can identify accurately abnormal stomach wall thickening andintraabdominal tumor extension. And CT is important for palnning of treatment, assessing surgical resectability,postoperative evaluation and prognostic implications. Author reviewed CT scan of 67 cases of confirmed gastriccancer by double contrast UGI or endoscopic biopsy, for 29 months from March 1983 to August 1985 at Department ofRadiology, Pusan National University Hospital. The results were as follows: 1. The most frequent site ofinvolvement of gastric cancer was gastric antrum in 49.9%(33/67). 2. By CT staging, stage 3 was 40.2%(27/67) andstage 4 was 38.8%(26/67). 3. In CT scan analysis, the structures involved by diect invasion were regional lymphnodes, pancrease, and gastrocolic ligament in order of frequency. The structures involved by distant metastaseswere liver, systemic lymph nodes, and mesentery in order of requency. 4. The diagnostic accuracy of CT staging was73.9%(17/23) by correlation of surgical and pathological findings. 5. In determination of stage by CT, the rate ofin accuracy of stage 2 was highest as 33%(2/6), and that of stage 3 was 29.2%(3/11). 6. Of all misdiagnoses,83.3%(5/6) was owing to failure to differentiate lymph node invasion from reactive hyperplasia of lymph node.
Biopsy ; Busan ; Endoscopy ; Gastrointestinal Tract ; Humans ; Hyperplasia ; Korea ; Ligaments ; Liver ; Lymph Nodes ; Mesentery ; Pancreas ; Pancrelipase ; Pyloric Antrum ; Stomach ; Stomach Neoplasms ; Tomography, X-Ray Computed

In a retrospective study of 21 patients, in whom the acetabular fractures were suspected on initialradiographs, we compared and analysed the CT findings and plain radiographic findings and plain radiographicfindings. The results were as follow: 1. In patients with multiple trauma, no further change in position wasrequeired during CT examinations. 2. CT showed intraarticular loose bodies, which were invisible on plainradiographs. 3. CT was useful in detecting the fractures of acetabular rims, medial wall of acetabulum, andfemoral head. 4. CT permitted better evaluation of shape, extent, and degree of separation of fracture fragments.5. CT was helpful indetecting the associated fractures and soft tissue injuries. 6. CT also demonstrated theadequacy of reduction, the position of metallic fixation devices, and the presence or absence of remainingintraarticular osseous fragments after surgery.
Acetabulum ; Head ; Humans ; Multiple Trauma ; Retrospective Studies ; Soft Tissue Injuries

No abstract available.
Electrodiagnosis ; Hypokalemic Periodic Paralysis ; Neural Conduction* ; Paralysis* ; Thyrotoxicosis

No abstract available.
Thyroid Gland* ; Thyroiditis*

No abstract available.
Lung*

BACKGROUND: Arsenics have been used for various medical purposes. These arsenics can cause different kinds of cutaneous and internal malignancies. The arsenic-induced malignancies can be fatal or cause severe morbidity. OBJECTIVE: For early detection and prevention of the arsenic-induced malignancies, the authors analyzed the clinical characteristics of arsenic-induced skin diseases. METHODS: Medical records of 15 patients(10 males, 5 females) with arsenical keratosis(AK) during a period from September 1994 to October 1999 were reviewed. Interview, physical examinations, skin biopsy, and laboratory tests were performed. RESULTS: 14 patients used Korean proprietary pills(KPP, "Hwan-Yak"), which were suspected to contain certain amount of arsenics, as a drug for treatment of certain diseases such as vitiligo(4 patients, 26.7%), laceration, syphilis, etc. The other formulation of medication was Salvarsan injection. Age at KPP or Salvarasan medication was from seven to thirty-five years old. Duration of medication was from one month to four years. Bowen's disease(BD), squamous cell carcinoma(SCC) and basal cell carcinoma(BCC) were detected in ten(66.7%), three(20%) and one(6.7%) patients, respectively. One(6.7%) patient had lung cancer. Sites of predilection were palmoplantar area(100%) for AK, trunk(60%) for BD and lower extremities(45%) for SCC and BCC. CONCLUSION: Chronic exposure to arsenic can induce the cutaneous and systemic malignancies. To prevent these malignancies, strict managements and supervising programs on certain arsenic-containing drugs(probably KPPs) are required, and regular cutaneous and systemic examinations for the patients with AK should be performed.
Arsenic ; Arsphenamine ; Biopsy ; Humans ; Keratosis* ; Lacerations ; Lung Neoplasms ; Male ; Medical Records ; Physical Examination ; Skin ; Skin Diseases ; Skin Neoplasms ; Syphilis