1.Neuroendocrine immunoperoxidase markers to predict chemotherapy response in lung cancer patients.
Hyuk JUNG ; Sang Jae LEE ; Un Sub PARK
Journal of the Korean Cancer Association 1993;25(5):664-672
No abstract available.
Drug Therapy*
;
Humans
;
Lung Neoplasms*
;
Lung*
2.The Factors Affecting The Prognosis of Arthroscopic Meniscectomy
Jung Man KIM ; Nam Yong CHOI ; Heung Sub LEE
The Journal of the Korean Orthopaedic Association 1985;20(3):439-444
Between May 1982 and October 1983, arthroscopic meniscectomy had been performed in 54 knees between ages of 11 and 70 years. There were 32 male patients and 22 female patients in this series. The mean follow-up was 20 months, ranging from 15 months to 33 months. Postoperative complications developed were retropatellar tenderness and effusion. No infection, thrombophlebitis or instability occurred postoperatively. The aim of this study was to evaluate the effect of the various possible prognostic factors upon the developtnent of the above mentioned complications. The factors included were 1) shape of tear, 2) ligamentous injury, 3) degenerative arthritia, 4) discoid lateral meniscus, 5) quadriceps atrophy, 6) sites of meniscus(medial or lateral) & extent of excision, 7) preoperative retropatellar tenderness and 8) method of rehabilitation. The findings were statistically analyzed by the Chi-square test (df-1) & Fisher's direct probability method. The results obtained were as follows; 1. The rate of development of postoperative effusion was significantly high in cases of quadriceps atrophy (P<0.01) and preoperative retropatellar tenderness(P<0.01). 2. The rate of deveopment of postoperative retropatellar tenderness was significantly high in case of discoid lateral meniscus (P <0.01). 3. There was no significant correlation between complications and other factors including shape of tear, preoperative degerative arthritis, site of meniscus & extent of excision and methods of rehabilitation.
Arthritis
;
Atrophy
;
Female
;
Follow-Up Studies
;
Humans
;
Knee
;
Ligaments
;
Male
;
Menisci, Tibial
;
Methods
;
Postoperative Complications
;
Prognosis
;
Rehabilitation
;
Tears
;
Thrombophlebitis
3.Comparison of Diagnostic Accuracy in Uterine Pathology among HSG, Hysteroscopy, and Sono-Hysterography.
Sun Hee CHA ; Jung Kyo CHOE ; You Me LEE ; Wee Hyun LEE ; Kyung Sub CHA
Korean Journal of Obstetrics and Gynecology 1997;40(8):1662-1668
Hysterosalpingography and Hysteroscopy have been used for the detection of intraute-rine pathology such as polyps, submucous myomas, intrauterine adhesion and endometrial hyperplasia or cancer. Recently the ultrasound has also been utilized for the detection of uterine pathology. Therefore the purpose of this study was to evaluate the diagnostic efficacy of SonoHysterography in detection of intrauterine pathology compared with HSG and Hysteroscopy. 32 patients underwent Sono-Hysterography and Hysteroscopy for the evaluation of the uterine pathology from september 1995 to January 1996. Nine of 32 patients had infertility problem and HSG performed prior to Sono-Hysterography and Hysteroscopy. The results are as follows : 1. The patients' ages ranged from 20 to 50 years(median 37.9). 2. All 9 patients with infertility who had positive HSG findings in uterine cavity showed the intrauterine pathology in Sono-Hysterography as well as Hysteroscopy. The detail findings are as follows :septated uterus(n=2), intrauterine adhesion :IUA(n=3), endometrial polyp(n=3), and IUA combined endmetrial hyperplasia(n=1). 3. Twenty two of 23 patients with abnormal uterine bleeding showed the intrauterne pathology and one patient had negative finding in Sono-Hysterography. However, Hysteroscopy revealed positive intrauterine pathology in 22 patients who had abnormal uterine bleeding. One patients who had positive finding in Sono-Hysterograply showed negative by Hysterography. In contrast, one patient who had negative finding in Sono-Hysterography had positive uterine pathology with polyp in Hysteroscopy. The histologic pathology in all 23 patients reported endometrial polyp(n=12), placental polyp(n=2), submucous myoma(n=1), endometrial hyperplasia(n=5), endometrial cancer(n=1), normal endometrial finding(n=2). 4. Sono-Hysterography, therefore, has a sensitivity and positive predictive value of 96.6%, 93.5% respectively. Our study showed a positive Sono-Hysterography is very predictive of the intrauterine pathology. Sono-Hysterography is safe, quick and minimal invasive procedure. So it is an invaluable technique in the evaluation of uterine cavity.
Endometrial Hyperplasia
;
Female
;
Humans
;
Hysterosalpingography
;
Hysteroscopy*
;
Infertility
;
Myoma
;
Pathology*
;
Polyps
;
Ultrasonography
;
Uterine Hemorrhage
4.Supplement of Incomplete Apoptosis Through CD8/Fas Chimeric Molecule by PMA of IFN-gamma.
Sang Kyou LEE ; Jae Hyuck SHIM ; Jung Hee LIM ; Jae Young LEE ; Young Sub SONG
Korean Journal of Immunology 1998;20(2):203-209
No abstract available.
5.Pachydermoperiostosis in a 19 Year-old Boy Presenting as an Acromegaly-like Syndrome.
Jung Sub LIM ; Jun A LEE ; Dong Ho KIM ; Kyung Jin LIM ; Dae Geun JEUN
Journal of Korean Society of Pediatric Endocrinology 2004;9(2):213-219
A nineteen year-old boy with progressive enlargement of the joints and distal extremities, clubbing, coarse facial features and hyperhidrosis was investigated. In physical examination, thickening of the scalp with furrowing (cutis verticis gyrata) and greasy thickening of skin (pachyderma) was prominent. His endocrine profile was normal. Radiological studies demonstrated bilateral symmetrical periosteal new bone formation with acroosteolysis and incidental microadenoma of pituitay gland. After extensive investigation to exclude systemic and endocrine causes, the patient was diagnosed as pachydermoperiostosis (PDP). PDP is a rare syndrome manifested clinically by finger clubbing, extremity enlargement, hypertrophic skin changes, and periosteal bone formation. The pathogenesis of the disorder has not been clarified though few endocrine abnormalities were seen. To aware of these clinical phenotype would help to differentiate PDP from acromegaly.
Acro-Osteolysis
;
Acromegaly
;
Extremities
;
Fingers
;
Humans
;
Hyperhidrosis
;
Joints
;
Male*
;
Osteoarthropathy, Primary Hypertrophic*
;
Osteogenesis
;
Phenotype
;
Physical Examination
;
Scalp
;
Skin
;
Young Adult*
6.a case of type II lissencephaly; Walker-Earburg syndrome.
Ae Yong KIM ; Jung Ho LEE ; Yong Sub KIM ; Kyeng Sook CHO ; Jong Dai JO
Journal of the Korean Pediatric Society 1991;34(11):1598-1604
No abstract available.
Lissencephaly*
;
Walker-Warburg Syndrome
7.Prevalence, Pathophysiology, Screening and Management of Osteoporosis in Gastric Cancer Patients.
Journal of Gastric Cancer 2011;11(1):7-15
Osteoporosis in gastric cancer patients is often overlooked or even neglected despite its high prevalence in these patients. Considering that old age, malnutrition, chronic disease, chemotherapy, decreased body mass index and gastrectomy are independent risk factors for osteoporosis, it is reasonable that the prevalence of osteoporosis in gastric cancer patients would be high. Many surviving patients suffer from back pain and pathological fractures, which are related to osteoporosis. Fractures have obvious associated morbidities, negative impact on quality of life, and impose both direct and indirect costs. In the era of a >55.6% 5-year survival rate of gastric cancer and increased longevity in gastric cancer patients, it is very important to eliminate common sequelae such as osteoporosis. Fortunately, the diagnosis of osteoporosis is well established and many therapeutic agents have been shown to be effective and safe not only in postmenopausal females but also in elderly males. Recently, effective treatments of gastric cancer patients with osteoporosis using bisphosphonates, which are commonly used in postmenopausal woman, were reported.
Aged
;
Back Pain
;
Body Mass Index
;
Chronic Disease
;
Diphosphonates
;
Female
;
Fractures, Spontaneous
;
Gastrectomy
;
Humans
;
Longevity
;
Male
;
Malnutrition
;
Mass Screening
;
Osteoporosis
;
Prevalence
;
Quality of Life
;
Risk Factors
;
Stomach Neoplasms
;
Survival Rate
8.A Psychiatric Study on Hahn.
Sung Kil MIN ; Jong Sub LEE ; Jung Ok HAN
Journal of Korean Neuropsychiatric Association 1997;36(4):603-611
OBJECTIVE: This study aimed at identifying the etiological background, symptomatic expressions, defense styles and coping strategies related to hahn. METHOD: The subjects were given a questionnaire for demographic data, life experiences and psychological and physical symptoms, Bond's questionnaire of defense style, and Weisman's scale for coping strategies and scales for severity of hahn and hwabyung. The subjects were 110 normal healthy adults and 151 patients with neurotic disorders, diagnosed with ICD-9. RESULTS: More vivid hahn was found in the married women, the less educated, and those from a low socio-economic state. In the area of etiological life experiences, hahn is significantly related with an unhappy and frustrated marital life, unsatisfactory filial Piety, Poor family background, poverty, little education, a hard life since childhood, betrayal, failure in business, personality problems, injustice in society and resignation to fate. Hahn, unresolved and accumulated, was believed to cause various psychological and physical illnesses. In many cases hahn was corhad been dealt with by simple suppression and being dependent on religious faith or sharing and communicating with people. More people considered hahn as one of the etiologies of hwabyung, a chronic anger syndrome. Hahn of patients with hwabyung was more serious than that of those without hwabyung. Symptoms of hahn were - in addition to various symptoms of depression, anxiety and other neurotic conditions or somatization - a mass in the epigastrium, sighing, something pushing-up in the chest, paranoid ideas and hyprochondria sis nor hygochondriacal ideas. On the other hand, hypersensitivity and irritability were less significant. Defense styles and coping strategies related with hahn were somatization, splitting-projection, passive-aggressiveness, incorporation, primitive idealization, stimulus reduction, self-pity and shared-concerns and dependency. CONCLUSION: These results suggest that hahn is an unique emotional condition which is characterized by culture-related somatization symptoms, paranoid ideas and hypochondriasis, in addition to general neurotic symptoms such as depression and anxiety and related somatic symptoms.
Adult
;
Anger
;
Anxiety
;
Commerce
;
Depression
;
Education
;
Female
;
Hand
;
Humans
;
Hypersensitivity
;
Hypochondriasis
;
International Classification of Diseases
;
Life Change Events
;
Neurotic Disorders
;
Poverty
;
Surveys and Questionnaires
;
Thorax
;
Weights and Measures
9.The May-Hegglin Anomaly in a Family.
Jung Ho LEE ; Su Yeon PARK ; Yong Sub KIM ; Jong DAI ; Byung Chang KIM
Journal of the Korean Pediatric Society 1994;37(10):1449-1452
The May-Hegglin anomaly is a rare autosomal dominant trait characterized by platelet abnormalities in the peripheral blood and large (up to 5mu) pale blue staining inclusions in the cytoplasm of neutrophils, eosinophils, basophils, and monocytes. We experienced a case of May-Hegglin anomaly in a 7 year old male and another case out of his family. His initial complaints at the admission were petechiae and intermittent epistaxis. Diagnosis was confirmed by peripheral blood smear and family study. We report the case with brief review of related literature.
Basophils
;
Blood Platelets
;
Child
;
Cytoplasm
;
Diagnosis
;
Eosinophils
;
Epistaxis
;
Humans
;
Male
;
Monocytes
;
Neutrophils
;
Purpura
10.A Clinical Observation on Neonatal Bacterial Meningitis.
Young Ju LEE ; Bu Kwun JUNG ; Soon Ok BYUN ; Myung Hi SHIN ; Ji Sub OH
Journal of the Korean Pediatric Society 1983;26(9):872-883
No abstract available.
Meningitis, Bacterial*