1.Neuroendocrine immunoperoxidase markers to predict chemotherapy response in lung cancer patients.
Hyuk JUNG ; Sang Jae LEE ; Un Sub PARK
Journal of the Korean Cancer Association 1993;25(5):664-672
No abstract available.
Drug Therapy*
;
Humans
;
Lung Neoplasms*
;
Lung*
2.The Factors Affecting The Prognosis of Arthroscopic Meniscectomy
Jung Man KIM ; Nam Yong CHOI ; Heung Sub LEE
The Journal of the Korean Orthopaedic Association 1985;20(3):439-444
Between May 1982 and October 1983, arthroscopic meniscectomy had been performed in 54 knees between ages of 11 and 70 years. There were 32 male patients and 22 female patients in this series. The mean follow-up was 20 months, ranging from 15 months to 33 months. Postoperative complications developed were retropatellar tenderness and effusion. No infection, thrombophlebitis or instability occurred postoperatively. The aim of this study was to evaluate the effect of the various possible prognostic factors upon the developtnent of the above mentioned complications. The factors included were 1) shape of tear, 2) ligamentous injury, 3) degenerative arthritia, 4) discoid lateral meniscus, 5) quadriceps atrophy, 6) sites of meniscus(medial or lateral) & extent of excision, 7) preoperative retropatellar tenderness and 8) method of rehabilitation. The findings were statistically analyzed by the Chi-square test (df-1) & Fisher's direct probability method. The results obtained were as follows; 1. The rate of development of postoperative effusion was significantly high in cases of quadriceps atrophy (P<0.01) and preoperative retropatellar tenderness(P<0.01). 2. The rate of deveopment of postoperative retropatellar tenderness was significantly high in case of discoid lateral meniscus (P <0.01). 3. There was no significant correlation between complications and other factors including shape of tear, preoperative degerative arthritis, site of meniscus & extent of excision and methods of rehabilitation.
Arthritis
;
Atrophy
;
Female
;
Follow-Up Studies
;
Humans
;
Knee
;
Ligaments
;
Male
;
Menisci, Tibial
;
Methods
;
Postoperative Complications
;
Prognosis
;
Rehabilitation
;
Tears
;
Thrombophlebitis
3.Supplement of Incomplete Apoptosis Through CD8/Fas Chimeric Molecule by PMA of IFN-gamma.
Sang Kyou LEE ; Jae Hyuck SHIM ; Jung Hee LIM ; Jae Young LEE ; Young Sub SONG
Korean Journal of Immunology 1998;20(2):203-209
No abstract available.
4.Comparison of Diagnostic Accuracy in Uterine Pathology among HSG, Hysteroscopy, and Sono-Hysterography.
Sun Hee CHA ; Jung Kyo CHOE ; You Me LEE ; Wee Hyun LEE ; Kyung Sub CHA
Korean Journal of Obstetrics and Gynecology 1997;40(8):1662-1668
Hysterosalpingography and Hysteroscopy have been used for the detection of intraute-rine pathology such as polyps, submucous myomas, intrauterine adhesion and endometrial hyperplasia or cancer. Recently the ultrasound has also been utilized for the detection of uterine pathology. Therefore the purpose of this study was to evaluate the diagnostic efficacy of SonoHysterography in detection of intrauterine pathology compared with HSG and Hysteroscopy. 32 patients underwent Sono-Hysterography and Hysteroscopy for the evaluation of the uterine pathology from september 1995 to January 1996. Nine of 32 patients had infertility problem and HSG performed prior to Sono-Hysterography and Hysteroscopy. The results are as follows : 1. The patients' ages ranged from 20 to 50 years(median 37.9). 2. All 9 patients with infertility who had positive HSG findings in uterine cavity showed the intrauterine pathology in Sono-Hysterography as well as Hysteroscopy. The detail findings are as follows :septated uterus(n=2), intrauterine adhesion :IUA(n=3), endometrial polyp(n=3), and IUA combined endmetrial hyperplasia(n=1). 3. Twenty two of 23 patients with abnormal uterine bleeding showed the intrauterne pathology and one patient had negative finding in Sono-Hysterography. However, Hysteroscopy revealed positive intrauterine pathology in 22 patients who had abnormal uterine bleeding. One patients who had positive finding in Sono-Hysterograply showed negative by Hysterography. In contrast, one patient who had negative finding in Sono-Hysterography had positive uterine pathology with polyp in Hysteroscopy. The histologic pathology in all 23 patients reported endometrial polyp(n=12), placental polyp(n=2), submucous myoma(n=1), endometrial hyperplasia(n=5), endometrial cancer(n=1), normal endometrial finding(n=2). 4. Sono-Hysterography, therefore, has a sensitivity and positive predictive value of 96.6%, 93.5% respectively. Our study showed a positive Sono-Hysterography is very predictive of the intrauterine pathology. Sono-Hysterography is safe, quick and minimal invasive procedure. So it is an invaluable technique in the evaluation of uterine cavity.
Endometrial Hyperplasia
;
Female
;
Humans
;
Hysterosalpingography
;
Hysteroscopy*
;
Infertility
;
Myoma
;
Pathology*
;
Polyps
;
Ultrasonography
;
Uterine Hemorrhage
5.A Study of Murder in Schizophrenic Patients Characteristics of the murders of family and nonfamily homicides.
Hyun Jung LEE ; Kwon Soo PARK ; Sang Sub CHOI
Korean Journal of Legal Medicine 1999;23(2):37-41
Sixty schizophrenia patients who committed homicide and detained after January 1, 1993 were divided in two groups, depending on whether their victim was a family member or not. Below conclusions were deduced from the comparison of the two groups in terms including demographic characteristics, onset and duration of illness, IQ score, suicidal attempts, history of alcohol/drug abuse or past crime, neuropsychiatric ward admission history, living circumstance, conflict with the victim, and adolescent conducting behavior. 1. More in the family homiciding patients (FHP) group lived alone due their unmarried, divorced, or separated marital status than those in the non-family homiciding patients (NFHP) group. More in the FHP group were in married state than those in NFHP group. 2. More in the NFHP group stayed alone apart from their family, while more in the FHP group lived with their family. 3. Those in the NFHP group show more frequent suicidal attempts than those in the FHP group, implying they have difficulties in the control of their impulsive behaviors. 4. To prevent the crime, it is essential for the government to practice the systematic support and care of the schizophrenia patients who are living alone, especially those without relative.
Adolescent
;
Crime
;
Divorce
;
Homicide*
;
Humans
;
Impulsive Behavior
;
Marital Status
;
Schizophrenia
;
Single Person
6.Body Composition Changes in Korean Children and Adolescents.
Journal of Korean Society of Pediatric Endocrinology 2010;15(1):7-13
The term body composition describes the percentages of fat, bone, and muscle in the human body; it reflects the nutritional or growth status in children and adolescents. Further, its evaluation is clinically important to assess the nutritional abnormalities, growth failure, progress of chronic diseases, or treatment measures for these conditions. Body composition parameters such as total body fat and fat distribution are risk factors for metabolic disease not only in adults but also in children and adolescents. Inadequate bone mineral acquisition and failure to achieve peak bone mass is a risk for subsequent osteoporosis. Therefore, measuring the body composition is important to ascertain the natural course of metabolic diseases and to develop strategies for their prevention because the body composition of children and adolescents is predictive of their body composition as adults. This article will review the basic concept and methods of measuring body composition. This review also deals with the evaluation of body composition in Korean children and adolescents. Because the body composition of individuals differs with age, body weight, puberty, sex, race, and ethnicity, it is important for pediatricians to know the characteristics of the body composition change in Korean children and adolescents.
Adipose Tissue
;
Adolescent
;
Adult
;
Body Composition
;
Body Weight
;
Child
;
Chronic Disease
;
Continental Population Groups
;
Humans
;
Metabolic Diseases
;
Muscles
;
Osteoporosis
;
Puberty
;
Risk Factors
7.Tracking the Fate of Muscle-derived Stem Cells: an Insight into the Distribution and Mode of Action.
Hyung Sub PARK ; Geum Hee CHOI ; Soli HAHN ; Young Sun YOO ; In Mok JUNG ; Taeseung LEE
Vascular Specialist International 2014;30(1):11-18
PURPOSE: To examine the fate of muscle-derived stem cells (MDSC) after injection into different host conditions and provide an insight for their mechanism of action. MATERIALS AND METHODS: MDSCs differentiated in vitro towards the endothelial lineage and transfected with lentivirus tagged with green fluorescent protein (GFP) were injected into two animal models mimicking vascular diseases: hindlimb ischemia and carotid injury models. Injected cells were tracked at the site of injection and in remote organs by harvesting the respective tissues at different time intervals and performing immunofluorescent histological analyses. Stem cell survival was quantified at the site of injection for up to 4 weeks. RESULTS: MDSCs were successfully tagged with fluorescent material GFP and showed successful implantation into the respective injection sites. These cells showed a higher affinity to implant in blood vessel walls as shown by double fluorescent co-stain with CD31. Quantification of stem cell survival showed a time-dependent decrease from day 3 to 4 weeks (survival rate normalized against day 3 was 72.0% at 1 week, 26.8% at 2 weeks and 2.4% at 4 weeks). Stem cells were also fo und in distant organs, especially the kidneys and liver, which survived up to 4 weeks. CONCLUSION: MDSCs were successfully tracked in different vascular disease models, and their fate was assessed in terms of cell survival and distribution. Better understanding of the donor cell properties, including their interaction with the host conditions and their mechanism of action, are needed to enhance cell survival and achieve improved outcomes.
Adult Stem Cells
;
Animals
;
Blood Vessels
;
Cell Survival
;
Hindlimb
;
Humans
;
Ischemia
;
Kidney
;
Lentivirus
;
Liver
;
Models, Animal
;
Stem Cell Niche
;
Stem Cells*
;
Tissue Donors
;
Vascular Diseases
8.Three Cases of Rotor Syndrome in Monozygotic Twin Brothers and Their Sister.
Jin Hwa JUNG ; Jeong Ho LEE ; Yong Sub KIM ; Jon Dae JO
Journal of the Korean Pediatric Society 1995;38(9):1270-1275
No abstract available.
Humans
;
Hyperbilirubinemia, Hereditary*
;
Siblings*
;
Twins, Monozygotic*
9.A Psychiatric Study on Hahn.
Sung Kil MIN ; Jong Sub LEE ; Jung Ok HAN
Journal of Korean Neuropsychiatric Association 1997;36(4):603-611
OBJECTIVE: This study aimed at identifying the etiological background, symptomatic expressions, defense styles and coping strategies related to hahn. METHOD: The subjects were given a questionnaire for demographic data, life experiences and psychological and physical symptoms, Bond's questionnaire of defense style, and Weisman's scale for coping strategies and scales for severity of hahn and hwabyung. The subjects were 110 normal healthy adults and 151 patients with neurotic disorders, diagnosed with ICD-9. RESULTS: More vivid hahn was found in the married women, the less educated, and those from a low socio-economic state. In the area of etiological life experiences, hahn is significantly related with an unhappy and frustrated marital life, unsatisfactory filial Piety, Poor family background, poverty, little education, a hard life since childhood, betrayal, failure in business, personality problems, injustice in society and resignation to fate. Hahn, unresolved and accumulated, was believed to cause various psychological and physical illnesses. In many cases hahn was corhad been dealt with by simple suppression and being dependent on religious faith or sharing and communicating with people. More people considered hahn as one of the etiologies of hwabyung, a chronic anger syndrome. Hahn of patients with hwabyung was more serious than that of those without hwabyung. Symptoms of hahn were - in addition to various symptoms of depression, anxiety and other neurotic conditions or somatization - a mass in the epigastrium, sighing, something pushing-up in the chest, paranoid ideas and hyprochondria sis nor hygochondriacal ideas. On the other hand, hypersensitivity and irritability were less significant. Defense styles and coping strategies related with hahn were somatization, splitting-projection, passive-aggressiveness, incorporation, primitive idealization, stimulus reduction, self-pity and shared-concerns and dependency. CONCLUSION: These results suggest that hahn is an unique emotional condition which is characterized by culture-related somatization symptoms, paranoid ideas and hypochondriasis, in addition to general neurotic symptoms such as depression and anxiety and related somatic symptoms.
Adult
;
Anger
;
Anxiety
;
Commerce
;
Depression
;
Education
;
Female
;
Hand
;
Humans
;
Hypersensitivity
;
Hypochondriasis
;
International Classification of Diseases
;
Life Change Events
;
Neurotic Disorders
;
Poverty
;
Surveys and Questionnaires
;
Thorax
;
Weights and Measures
10.The May-Hegglin Anomaly in a Family.
Jung Ho LEE ; Su Yeon PARK ; Yong Sub KIM ; Jong DAI ; Byung Chang KIM
Journal of the Korean Pediatric Society 1994;37(10):1449-1452
The May-Hegglin anomaly is a rare autosomal dominant trait characterized by platelet abnormalities in the peripheral blood and large (up to 5mu) pale blue staining inclusions in the cytoplasm of neutrophils, eosinophils, basophils, and monocytes. We experienced a case of May-Hegglin anomaly in a 7 year old male and another case out of his family. His initial complaints at the admission were petechiae and intermittent epistaxis. Diagnosis was confirmed by peripheral blood smear and family study. We report the case with brief review of related literature.
Basophils
;
Blood Platelets
;
Child
;
Cytoplasm
;
Diagnosis
;
Eosinophils
;
Epistaxis
;
Humans
;
Male
;
Monocytes
;
Neutrophils
;
Purpura