1.Clinical Experience of Complete Neurologic Recovery from Severe Hypoxic Ischemic Encephalopathy after Cardiac Arrest.
Kyu Nam PARK ; Se Min CHOI ; Woon Jung LEE ; Ju Rang HAN ; Seung Hyun PARK ; Se Kyung KIM
Journal of the Korean Society of Emergency Medicine 1999;10(1):133-139
Prediction of individual outcome after cardiopulmonary resuscitation is of major medical, ethical, and socioeconomic interest but uncertain. We experienced the case thats the patient got complete neurologic recovery after the 123th day firm cardiac arrest, who had been suspected to go with poor prognosis because she got the findings of Glasgow Coma Scale 4, severe diffuse encephalopathy on encephalogram and generalized tonic-clonic seizure at the 4th day. Recently, a 29 year-old women who sustained from respiratory arrest induced presumably by sedative and anticonvulsant therapy for control of seizure that happened during local lidocaine anesthesia far mamoplasty was transfered to our emergency medical center from local private plastic office. Arrest time was about 20 minutes. On hospital arrival, she had a pulseless bradyasystole and no respiration, but spontaneous circulation was restored at 10 minutes artier CPR started. We started cerebral oriented resuscitation including mild hypothermia(34degrees C), hemodilution, calcium channel blocker infusion. On hospital day 4, patient's glasgow coma scale(GCS) was 4. On hospital clay 7, Brain Magnetic Resonance Imaging(MRI) showed high signal intensity on T2WI, involving the bilateral basal ganglia. After contrast administraton, marked enhancement can be seen at the lesion site. Patient's glasgow coma scale(GCS) increased step by step to 5 on 8th day, 7 on 14th day, 10 on 15th day, 13 on 17th day, 15 on 20th day. 40 days later the patient was discharged with minor neurologic abnormality including hand tremor, dysphonia, amenorrhea and Mini Mental State Examination(MMSE) score(26). Long-term Follow up revealed that all neurologic functional abnormality inducting hand tremor, dysphonia, amenorrhea and MMSE score(26) is completely recovered on 123th day after episode of cardiopulmonary arrest.
Adult
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Amenorrhea
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Anesthesia
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Basal Ganglia
;
Brain
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Calcium Channels
;
Cardiopulmonary Resuscitation
;
Coma
;
Dysphonia
;
Emergencies
;
Female
;
Follow-Up Studies
;
Glasgow Coma Scale
;
Hand
;
Heart Arrest*
;
Hemodilution
;
Humans
;
Hypoxia-Ischemia, Brain*
;
Lidocaine
;
Plastics
;
Prognosis
;
Respiration
;
Resuscitation
;
Seizures
;
Tremor
2.Prognostic Factors of Percutaneous Radiofrequency Neurotomy for Chronic Low Back Pain.
Hoon JOY ; Jung Yul PARK ; Se Hoon KIM ; Dong Joon LIM ; Jung Keun SUH
Journal of the Korean Geriatrics Society 2002;6(2):155-163
BACKGROUNDS: Percutaneous radiofrequency neurotomy of posterior primary ramus has been in use as a treatment for persistent, mechanical low back pain for two decades. However, there has been limited studies regarding to prognostic factors related to outcome. We report our experience with at least 2-year follow up with special aftention on prognostic factors. METHODS: Of total 228 patients who underwent percutaneous radiofrequency neurotomy (PRN) of posterior primary ramus for refractory low back pain during last 3 years, 128 patients whose pain was considered to be originated from facets joints or their surrounding soft tissue and responded to temporary blocks were assigned to a group II. All patients had more than 6 months of pain. These patients were compared with 100 patients to whom PRN were provided for chronic nonspecific low back pain without all inclusion criteria (Group I). RF procedures were done under local anesthesia with C-arm intensifier guidance. Pain reliefs were estimated at 1week, 1month, 6months and 2 years using visual analog scale(VAS). For patients with more that 50% reduction of previous pain was regarded as positive responder. Various clinical variables such as age, sex, symptom duration, types of pain, bilaterality, and previous surgery were studied for prognostic factors. RESULTS: Positive responders were 56% at 1week, 46% at lmonth, 18% at 6months, and 13% at 2years after PRN in group I, and 78.9% at lweek, 75.4% at lmonth, 62.5% at 6months, and 54.7% at 2years in group II. Some variables were found to be significantly related to outcome including prominent local tenderness, percussion tenderness, combination of symptoms with pain on gefting up, extension, transitional movement, pain radiating to buttock and/or posterior thigh, and good immediate response. Age, sex, symptom duration, bilaterality, imaging study results, previous lumbar surgery, and degrees of pain relief from diagnostic block were not related to outcome. CONCLUSIONS: These results indicate that PRN of posterior primary ramus has a moderate overall long-term beneficial effect, with no morbidity in our series. But, the long-term good results will be anticipated only in properly selected patients with low back pain originating from facet joints and surrounding structures.
Anesthesia, Local
;
Buttocks
;
Follow-Up Studies
;
Humans
;
Joints
;
Low Back Pain*
;
Percussion
;
Thigh
;
Zygapophyseal Joint
3.5alpha-Reductase.
Jung Se PARK ; Min Chul CHO ; Jae Seung PAICK
Korean Journal of Andrology 2012;30(1):1-12
Androgen acts via the androgen receptor and can play a critical role in the development and growth of the prostate and the pathophysiology of prostatic diseases. Testosterone is the most abundant circulating androgen and is converted to dihydrotestosterone (DHT), a more potent androgen, by steroid 5alpha-reductase. There are two 5alpha-reductase isoenzymes, type 1 and type 2, in humans and animals. Type 2 5alpha-reductase predominates in the prostate. While deficiency of type 2 5alpha-reductase causes male pseudohermaphroditism, increased DHT has been implicated in benign prostatic hyperplasia and prostate cancer. The aim of this article is to highlight the significance of 5alpha-reductase in the development and growth of the prostate and pathogenesis of prostatic diseases.
46, XY Disorders of Sex Development
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Animals
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Dihydrotestosterone
;
Growth and Development
;
Humans
;
Isoenzymes
;
Prostate
;
Prostatic Diseases
;
Prostatic Hyperplasia
;
Prostatic Neoplasms
;
Receptors, Androgen
;
Sexual Development
;
Testosterone
4.Cardiac Fibroma of the Ventricular Septum: A case report.
Byung Tae PARK ; Se Jin JANG ; Moon Hyang PARK ; Jung Dal LEE ; Hyo Jin LEE
Korean Journal of Pathology 1991;25(1):37-41
This is an autopsy case of a 6 month old girl who suddenly died of respiratory distress during sleep. She had suffered from mild but frequent episodes of common cold and was treated for eczema for several days. At autopsy, the heart was enlarged and weighed 100 gm. A firm and gray-white tumor, measuring 4.5 x 3.8 x 2.8 cm, was located in the interventricular septum and encroached upon the wall of left ventricle. The mass was well demarcated but was not encapsulated. Neither necrosis nor calcification was present. Microscopically the tumor was composed of haphazardly arranged bundles of collagen fibers and fibroblasts. Myocardial cells are intermingled with the fibroblasts at the margin of the tumor. Massive edema of the lung and congestion of the liver and spleen were pronounced.
5.Evaluation of hepatic pliability using supine and erect abdominal x-rays
Se Young JUNG ; Cheol Kyu PARK ; Seog Hee PARK ; Choon Yul KIM ; Yong Whee BAHK
Journal of the Korean Radiological Society 1986;22(4):499-502
Although many approaches have been attempted in the evaluation of liver size such as measurement of length,area and volume, the linear measurements have been used most frequently because of simplicity. We measured theliver size using 4 linear measurements for evaluation of hepatic pliability on plain abdominal film in the erectand the supine position. Our cases consisted of 125 persons who have no symptom or signs clinically and havenormal liver function test. The results were as follows: 1. The measurements of the liver size using diagonaldiameter(DD), oblique diameter of right lobe(OD), midline vertical diameter(MD) and height of right dome of theliver(HD) were ; 19.6+-1.8cm, 13.7+-1.6cm, 2.03+-0.4cm in the supine position; and 20.5+-2.1cm, 21.9+-2.1cm,15.4+-2.1cm, 1.87+-0.4cm in the erect position, respectively. 2. The differences of each diameter between erectand supine position were 0.9+-1.0cm in DD, 0.9+-1.0cm in OD and 1.7+-1.4cm in MD, and they were longer in thesupine position (p<0.001). 3. The HD was slinghtly longer in the supine position than in the erect position(p<0.001). 4. Among the 4 measurements, the largest difference of linear diameter between the erect and the supineposition was by MD. 5. We found the change or size and shape of the normal liver in the different position.
Humans
;
Liver
;
Liver Function Tests
;
Pliability
;
Supine Position
6.A Case of Bilateral Duplicating Systems Associated with Bilateral Ureteroceles.
Jung Se PARK ; Se Jin OH ; Kwang Sae KIM ; Sung Choon LEE
Korean Journal of Urology 1982;23(6):865-868
Ureteral duplication is the most common developmental abnormality of the upper urinary tract. The upper pole ureter is often associated with a ureterocele and the lower pole ureter, the V-U reflux. A case of bilateral double collecting system associated with bilateral ureteroceles in a 6-month old Korean male is presented with review of literature.
Humans
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Infant
;
Male
;
Ureter
;
Ureterocele*
;
Urinary Tract
7.Two Cases of Hemolytic Disease of Newborn due to Anti-E.
Se Won PARK ; Young Sun KIM ; Jung Hwan CHOI ; Hyo Seop AHN ; Chong Ku YUN
Journal of the Korean Pediatric Society 1986;29(2):85-90
No abstract available.
Erythroblastosis, Fetal*
;
Infant, Newborn
8.Prophylactic Treatment of Bladder Tumors by Thio-TEPA Instillations (II).
Korean Journal of Urology 1982;23(4):436-441
Study group consists of 30 cases whose follow-up period is over 6 months among 32 cases of bladder tumors treated with thio-TEPA instillation following TUR during the period from January, 1978 through June, 1981. Control group consists of 25 cases whose follow-up period is over 6 months among 33 cases of bladder tumors treated by TUR only during the period from January, 1971 through December, 1977. Following results were obtained: 1. Recurrence rate: In study group, 30% In control group, 64% 2. Interval between TUR & the first recurrence: In study group, average 8.1 months In control group, average 7.1 months 3. Number of tumors at first recurrence: In study group: 89%: under 2 11%: over 3 In control group: 25%: under 2 75%: over 3
Follow-Up Studies
;
Recurrence
;
Thiotepa*
;
Urinary Bladder Neoplasms*
;
Urinary Bladder*
9.Circulating immune complex in syphilis.
Min Geol LEE ; Ho KWAHCK ; Joo Young PARK ; Se Jong KIM ; Jung Bock LEE
Korean Journal of Dermatology 1991;29(4):481-490
No abstract available.
Antigen-Antibody Complex*
;
Syphilis*
10.Inhibitory effects of several drugs to intestinal secretory stimulation of heat-stable enterotoxin produced by enterotoxigenic E. coli.
Nam Ung YANG ; Jung Pyong PARK ; Hyun Kook RHEE ; Se Hyuk JU
Journal of the Korean Society for Microbiology 1991;26(3):223-231
No abstract available.
Enterotoxigenic Escherichia coli*
;
Enterotoxins*