1.Signet Ring Cell Variant of Invasive Lobular Carcinoma of Male Breast.
Seung Sam PAIK ; Seok Hoon JEON ; Moon Hyang PARK ; Pa Jong JUNG ; Jung Dal LEE
Korean Journal of Pathology 1997;31(2):179-181
Lobular carcinoma of the male breast is very rare, because of the absence of lobules in the normal male breast. Herein, a case of lobular carcinoma of the male breast with cellular features of signet ring cells is described. A 57-year-old man presented with a left breast mass. Histologic examination showed classic invasive lobular carcinoma with in situ component. Most infiltrating tumor cells had a prominent signet ring cell appearance. The patient was phenotypically male and had fathered children. There was no history of predisposing factors to breast lesion, such as hormone use or gynecomastia.
Breast*
;
Carcinoma, Lobular*
;
Causality
;
Child
;
Fathers
;
Gynecomastia
;
Humans
;
Male*
;
Middle Aged
2.Signet Ring Cell Variant of Invasive Lobular Carcinoma of Male Breast.
Seung Sam PAIK ; Seok Hoon JEON ; Moon Hyang PARK ; Pa Jong JUNG ; Jung Dal LEE
Korean Journal of Pathology 1997;31(2):179-181
Lobular carcinoma of the male breast is very rare, because of the absence of lobules in the normal male breast. Herein, a case of lobular carcinoma of the male breast with cellular features of signet ring cells is described. A 57-year-old man presented with a left breast mass. Histologic examination showed classic invasive lobular carcinoma with in situ component. Most infiltrating tumor cells had a prominent signet ring cell appearance. The patient was phenotypically male and had fathered children. There was no history of predisposing factors to breast lesion, such as hormone use or gynecomastia.
Breast*
;
Carcinoma, Lobular*
;
Causality
;
Child
;
Fathers
;
Gynecomastia
;
Humans
;
Male*
;
Middle Aged
3.A Case of Hereditary Anhidrotic Ectodermal Dysplasia.
Jong Won LEE ; Jin Kyung JUNG ; Jin Gun BANG ; Jin Sam RHO ; Jung Hee PARK
Journal of the Korean Pediatric Society 1994;37(10):1453-1456
Hereditary anhidrotic ectodermal dysplasia is a rare condition characterized by underdeveloped ectodermal structure including the skin, teeth or skin appendages. The patient has characteristic feature of anhidrosis, hypotrichosis and defective dentition. We experienced a case of hereditary anhidrotic ectodermal dysplasia in a l-month-old male infant who had unexplained recurring fever, anhidrosis and characteristic facial feature, so we established the diagnosis with clinical feature and skin biopsy.
Biopsy
;
Dentition
;
Diagnosis
;
Ectoderm
;
Ectodermal Dysplasia*
;
Fever
;
Humans
;
Hypohidrosis
;
Hypotrichosis
;
Infant
;
Male
;
Skin
;
Tooth
4.Ureteral Fibroepithelial Polyp: A report of four cases (One case with nephrogenic adenoma).
Won Mee LEE ; Seung Sam PAIK ; Eun Kyung HONG ; Moon Hyang PARK ; Jung Dal LEE
Korean Journal of Pathology 1996;30(8):715-720
Fibroepithelial polyps of the ureter are usually acquired rather than congenital. Most polyps are hamartomatous growths which tend to arise in the proximal portion of the left ureter. Most patients exibit either hematuria or persistent flank pain secondary to partial ureteral obstruction. Because of false positivity of urine cytology, as well as intravenous pyelogram, the correct diagnosis is confused with malignancy. Herein we report four cases of ureteral fibroepithelial polyp, which are associated with stones resulting in partial obstruction of the ureter. One of the four cases is associated with nephrogenic adenoma in the lamina propria of the adjacent ureter. The following report describes clinicopathologic findings of fibroepithelial polyp with review of literatures.
Adenoma
5.Histological Study of Ductus Arteriosus Affected by Indomethacin in the Fetal Rates.
Young Sook JANG ; Chang Yeoul JEON ; Heon Sook LEE ; Jung Soo KIM ; Moo Sam LEE
Journal of the Korean Pediatric Society 1983;26(8):770-777
No abstract available.
Ductus Arteriosus*
;
Indomethacin*
6.The effects of oophorectomy and hysterectomy on rat spine and tibia.
Soo Hyun CHO ; Jung Kwon CUNG ; Kyung Tai KIM ; Sam Hyun CHO ; Jai Auk LEE
Korean Journal of Obstetrics and Gynecology 1993;36(11):3784-3791
No abstract available.
Animals
;
Female
;
Hysterectomy*
;
Ovariectomy*
;
Rats*
;
Spine*
;
Tibia*
7.Ossifying Fibromyxoid Tumor of Soft Parts.
Seok Hoon JEON ; Seung Sam PAIK ; Eun Kyung HONG ; Moon Hyang PARK ; Jung Dal LEE
Korean Journal of Pathology 1997;31(2):174-178
An ossifying fibromyxoid tumor of soft parts is a rare, recently described, fibro-osseous neoplasm of uncertain histogenesis. It occurs most frequently within the subcutis or skeletal muscle of the extremities. Its biologic behavior is generally regarded as benign with at worst a locally aggressive clinical course. But, atypical and malignant variants have been recently reported. Herein we report a case of a benign ossifying fibromyxoid tumor which occurred in the left upper back of 41-year-old man. The tumor is composed of uniformly round or polygonal cells arranged in cords or nests which are separated by myxoid and hyalinzed fibrous matrix and associated with irregular bony trabeculae. The tumor cells are strong positive for vimentin. Ultrastructural findings and a review of literatures are added.
Adult
;
Extremities
;
Humans
;
Muscle, Skeletal
;
Vimentin
8.Ossifying Fibromyxoid Tumor of Soft Parts.
Seok Hoon JEON ; Seung Sam PAIK ; Eun Kyung HONG ; Moon Hyang PARK ; Jung Dal LEE
Korean Journal of Pathology 1997;31(2):174-178
An ossifying fibromyxoid tumor of soft parts is a rare, recently described, fibro-osseous neoplasm of uncertain histogenesis. It occurs most frequently within the subcutis or skeletal muscle of the extremities. Its biologic behavior is generally regarded as benign with at worst a locally aggressive clinical course. But, atypical and malignant variants have been recently reported. Herein we report a case of a benign ossifying fibromyxoid tumor which occurred in the left upper back of 41-year-old man. The tumor is composed of uniformly round or polygonal cells arranged in cords or nests which are separated by myxoid and hyalinzed fibrous matrix and associated with irregular bony trabeculae. The tumor cells are strong positive for vimentin. Ultrastructural findings and a review of literatures are added.
Adult
;
Extremities
;
Humans
;
Muscle, Skeletal
;
Vimentin
9.Clear Cell Islet Cell Tumor of the Pancreas: An Immunohistochemical and Ultrastructural study.
Seung Sam PAIK ; Young Ha OH ; Eun Kyung HONG ; Moon Hyang PARK ; Jung Dal LEE
Korean Journal of Pathology 1997;31(2):162-166
A clear cell islet cell tumor of the pancreas is extremely rare and characterized by extensive clear cell components. Electron microscopic and immunohistochemical findings are essential to prove that the mass with clear cells is an unusual manifestation of an islet cell tumor. Herein, we report a case of clear cell islet cell tumor of a 54-year-old woman with abdominal pain. The tumor was composed of polygonal clear cells arranged in nests, trabeculae, and ribbon pattern with the extensively fibrous stroma. These tumor cells showed strong reactivity for chromogranin and weak reactivity for somatostatin and glucagon. An electron microscope revealed that the important contributing factor of the clear cytoplasmic change was mainly due to an accumulation of lipid droplets, coupled with cytoplasmic swelling in some areas. Some tumor cells showed many endosecretory granules ranging from 111 to 297nm in diameter. In the clinical and immunohistochemical findings these granules were consistent with somatostatin granules in morphology and size.
Abdominal Pain
;
Adenoma, Islet Cell*
;
Cellular Structures
;
Cytoplasm
;
Female
;
Glucagon
;
Humans
;
Islets of Langerhans*
;
Middle Aged
;
Pancreas*
;
Somatostatin
10.Clear Cell Islet Cell Tumor of the Pancreas: An Immunohistochemical and Ultrastructural study.
Seung Sam PAIK ; Young Ha OH ; Eun Kyung HONG ; Moon Hyang PARK ; Jung Dal LEE
Korean Journal of Pathology 1997;31(2):162-166
A clear cell islet cell tumor of the pancreas is extremely rare and characterized by extensive clear cell components. Electron microscopic and immunohistochemical findings are essential to prove that the mass with clear cells is an unusual manifestation of an islet cell tumor. Herein, we report a case of clear cell islet cell tumor of a 54-year-old woman with abdominal pain. The tumor was composed of polygonal clear cells arranged in nests, trabeculae, and ribbon pattern with the extensively fibrous stroma. These tumor cells showed strong reactivity for chromogranin and weak reactivity for somatostatin and glucagon. An electron microscope revealed that the important contributing factor of the clear cytoplasmic change was mainly due to an accumulation of lipid droplets, coupled with cytoplasmic swelling in some areas. Some tumor cells showed many endosecretory granules ranging from 111 to 297nm in diameter. In the clinical and immunohistochemical findings these granules were consistent with somatostatin granules in morphology and size.
Abdominal Pain
;
Adenoma, Islet Cell*
;
Cellular Structures
;
Cytoplasm
;
Female
;
Glucagon
;
Humans
;
Islets of Langerhans*
;
Middle Aged
;
Pancreas*
;
Somatostatin